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Membranous-like glomerulopathy with masked IgG-k deposits in a pediatric patient with juvenile idiopathic arthritis
Membranous-like glomerulopathy with masked IgG-k deposits in a pediatric patient with juvenile idiopathic arthritis
Membranous-like glomerulopathy with masked IgG-kappa deposits (MGMID) is a rare entity described primarily among young fem...
AI-powered insights in pediatric nephrology: current applications and future opportunities
AI-powered insights in pediatric nephrology: current applications and future opportunities
Artificial intelligence (AI) is rapidly emerging as a transformative force in pediatric nephrology, enabling improvements ...
Progression of the estimated glomerular filtration rate in asphyxiated neonates undergoing therapeutic hypothermia during the first 10 days of life
Progression of the estimated glomerular filtration rate in asphyxiated neonates undergoing therapeutic hypothermia during the first 10 days of life
Serum creatinine (Scr) centile values were recently described in a cohort of 1136 (near)-term neonates that underwent ther...
Macrophage migration inhibitory factor and angiopoietin-like protein 4 as markers for steroid response in children with idiopathic nephrotic syndrome
Macrophage migration inhibitory factor and angiopoietin-like protein 4 as markers for steroid response in children with idiopathic nephrotic syndrome
Idiopathic nephrotic syndrome (INS) is a significant kidney disorder in pediatrics. Early diagnosis of minimal change dise...
Health-related quality of life, mental health and caregiver burden in children with autosomal recessive polycystic kidney disease
Health-related quality of life, mental health and caregiver burden in children with autosomal recessive polycystic kidney disease
Pediatric chronic kidney disease (CKD) causes significantly impaired health-related quality of life (hrQOL) and caregiver ...
Comparison of different equations for estimating the glomerular filtration rate in pediatric kidney transplant recipients
Comparison of different equations for estimating the glomerular filtration rate in pediatric kidney transplant recipients
Accurate glomerular filtration rate estimation (eGFR) is essential for managing pediatric kidney transplant recipients. Gi...
Adequacy and safety of pediatric native kidney biopsy using 16- and 18-gauge needles
Adequacy and safety of pediatric native kidney biopsy using 16- and 18-gauge needles
The native kidney biopsy is an important diagnostic procedure in pediatric nephrology. Recent meta-analyses did not find t...
A 1-year-old boy with MIRAGE syndrome and nephrotic syndrome, whose kidney histopathology revealed membranous nephropathy-like findings: a case report
A 1-year-old boy with MIRAGE syndrome and nephrotic syndrome, whose kidney histopathology revealed membranous nephropathy-like findings: a case report
MIRAGE syndrome is a rare multisystem disorder caused by gain-on-function SAMD9 variants. Kidney biopsies in some MIRAGE s...
Early fluid status and severe intraventricular hemorrhage or death in extremely preterm infants
Early fluid status and severe intraventricular hemorrhage or death in extremely preterm infants
Measures of early postnatal fluid balance may be associated with severe intraventricular hemorrhage (sIVH) and/or death in...
Correlation between polymorphisms of the gene and peritoneal function in children on chronic peritoneal dialysis
Correlation between polymorphisms of the gene and peritoneal function in children on chronic peritoneal dialysis
Aquaporins (AQPs) are a class of proteins that transport water molecules across membranes, which can promote water transpo...
New prognostic markers for IgA nephropathy in children
New prognostic markers for IgA nephropathy in children
IgA nephropathy (IgAN) is the most common glomerulonephritis worldwide, with significant implications for adults and child...
Urinary periostin as a novel non-invasive biomarker for kidney scarring in pediatric vesicoureteral reflux patients
Urinary periostin as a novel non-invasive biomarker for kidney scarring in pediatric vesicoureteral reflux patients
Vesicoureteral reflux (VUR) is a common pediatric urological condition associated with kidney scarring, which can lead to ...
Urinary leukotriene E4 for predicting steroid sensitivity in children with nephrotic syndrome: an observational cohort study
Urinary leukotriene E4 for predicting steroid sensitivity in children with nephrotic syndrome: an observational cohort study
Nephrotic syndrome (NS) is a common pediatric kidney disorder characterized by proteinuria, hypoalbuminemia, and edema. Le...
Emphysematous pyelonephritis and infection-related calculi
Emphysematous pyelonephritis and infection-related calculi
Emphysematous pyelonephritis (EPN) is a critical and life-threatening necrotizing urinary tract infection, marked by gas f...
Impact of urinary extravasation in posterior urethral valves: clinical implications of urinomas and ascites on kidney function
Impact of urinary extravasation in posterior urethral valves: clinical implications of urinomas and ascites on kidney function
Urinary extravasation (UE) in patients with posterior urethral valves (PUV), in the form of urinomas or urinary ascites, i...
Comparative efficacy of alteplase and urokinase in pharmacomechanical thrombolysis of permanent double lumen hemodialysis catheters in children
Comparative efficacy of alteplase and urokinase in pharmacomechanical thrombolysis of permanent double lumen hemodialysis catheters in children
Thrombotic occlusion of permanent double lumen catheters (PDLC) in hemodialysis has traditionally been treated with urokin...
Molecular Mechanisms of Perivascular Macrophages in Alzheimer’s Disease: Insights from Single-Cell Sequencing and Mendelian Randomization
Molecular Mechanisms of Perivascular Macrophages in Alzheimer’s Disease: Insights from Single-Cell Sequencing and Mendelian Randomization
Alzheimer’s disease (AD) is a leading cause of dementia characterized by neuroinflammation and immune dysregulation....
Molecular Consequences of a Missense Variant, c.1285G > A, Associated With Syndromic Neurodevelopmental Disorder
Molecular Consequences of a Missense Variant, c.1285G > A, Associated With Syndromic Neurodevelopmental Disorder
PHF21A is a histone reader protein that recognizes unmethylated H3 lysine 4 and binds to DNA through its AT-hook motif. PH...
Inhibition of P2Y6 Receptor-Mediated Microglia Phagocytosis Aggravates Brain Injury in Mice of Intracerebral Hemorrhage
Inhibition of P2Y6 Receptor-Mediated Microglia Phagocytosis Aggravates Brain Injury in Mice of Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) is a devastating stroke subtype leading to severe sensorimotor dysfunction. Many studies sh...
The Role of Estrogen in Mitochondrial Disease
The Role of Estrogen in Mitochondrial Disease
This review aims to investigate the potential role of estrogen in various mitochondrial diseases, such as Leber’s He...
A Technical Assessment of a Commercial GFAP Lateral Flow Assay to Establish Proof-of-Concept for Use in Traumatic Brain Injury
A Technical Assessment of a Commercial GFAP Lateral Flow Assay to Establish Proof-of-Concept for Use in Traumatic Brain Injury
Glial fibrillary acidic protein (GFAP) is an emerging biomarker for the detection of acute intracranial pathology followin...
Targeting Neuronal Alpha7 Nicotinic Acetylcholine Receptor Upregulation in Age-Related Neurological Disorders
Targeting Neuronal Alpha7 Nicotinic Acetylcholine Receptor Upregulation in Age-Related Neurological Disorders
The multifunctional roles of alpha7 nicotinic acetylcholine receptors (α7nAChRs), ranging from cognitive enhancement,...
MicroRNAs as Diagnostic Biomarkers of Myasthenia Gravis: A Systematic Review and Meta-Analysis
MicroRNAs as Diagnostic Biomarkers of Myasthenia Gravis: A Systematic Review and Meta-Analysis
Myasthenia gravis (MG) is an autoimmune neuromuscular disorder characterized by fluctuating muscle weakness. MicroRNAs (mi...
Sex-Specific Neuropsychiatric Effects of Subanesthetic Ketamine Exposure in Pregnant Mice and Their Offspring
Sex-Specific Neuropsychiatric Effects of Subanesthetic Ketamine Exposure in Pregnant Mice and Their Offspring
Depression during pregnancy is often overlooked and undertreated. Ketamine has been shown to exert prompt and sustained an...
The Crosstalk Between Ferritinophagy and Ferroptosis in Ischemic Stroke: Regulatory Mechanisms and Therapeutic Implications
The Crosstalk Between Ferritinophagy and Ferroptosis in Ischemic Stroke: Regulatory Mechanisms and Therapeutic Implications
Ischemic stroke is a common cerebrovascular disease accompanied by a large number of neuronal death and severe functional ...
Kynurenine Pathway Modulation by Exercise in Multiple Sclerosis: Implications for Neuroprotection and Inflammation
Kynurenine Pathway Modulation by Exercise in Multiple Sclerosis: Implications for Neuroprotection and Inflammation
Multiple Sclerosis (MS) is a chronic, inflammatory, and neurodegenerative disease of the Central Nervous System (CNS) that...
Neural Circuit Mapping and Neurotherapy-Based Strategies
Neural Circuit Mapping and Neurotherapy-Based Strategies
Recent developments in neural circuit mapping and neurotherapy are changing our understanding of the dynamic network struc...
Identification of Novel Scaffolds Against GSK-3 for Targeting Alzheimer’s Disease Through Molecular Modeling Techniques
Identification of Novel Scaffolds Against GSK-3 for Targeting Alzheimer’s Disease Through Molecular Modeling Techniques
Alzheimer’s disease (AD) is one of the most common causes of dementia in elderly populations. A multifactorial and c...
Role of Repressive Histone Lysine Demethylases and Methylases in Susceptibility to Depression Using a Novel Progressive Social Defeat Stress Mouse Model
Role of Repressive Histone Lysine Demethylases and Methylases in Susceptibility to Depression Using a Novel Progressive Social Defeat Stress Mouse Model
Major depressive disorder (MDD) results from repeated and constant exposure to stress over prolonged periods. The highly v...
The Cerebral Lymphatic System: Function, Controversies, and Therapeutic Approaches for Central Nervous System Diseases
The Cerebral Lymphatic System: Function, Controversies, and Therapeutic Approaches for Central Nervous System Diseases
The meninges serve as critical barriers that maintain immune homeostasis in the central nervous system (CNS) and play vita...
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