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Multiplex quantification of endocrine proteins in volumetric dried blood spots
Multiplex quantification of endocrine proteins in volumetric dried blood spots
Circulating proteins are routinely quantified from liquid biopsies to deduce health and disease. Among these are endocrine...
Comprehensive analysis of chronic hepatitis B concurrent with non-alcoholic fatty liver disease: a proteomics report based on clinical liver samples
Comprehensive analysis of chronic hepatitis B concurrent with non-alcoholic fatty liver disease: a proteomics report based on clinical liver samples
In recent years, the prevalence of non-alcoholic fatty liver disease (NAFLD) has risen among patients with chronic hepatit...
From blood drops to biomarkers: a scoping review of microsampling in mass spectrometry-based proteomics
From blood drops to biomarkers: a scoping review of microsampling in mass spectrometry-based proteomics
Microsamples are simple blood sampling procedures utilizing small blood draws. Although microsamples are regularly used in...
Integrating multimodal data to predict the progression of hormone-sensitive prostate cancer
Integrating multimodal data to predict the progression of hormone-sensitive prostate cancer
Identifying the population at risk of rapid progression from hormone-sensitive prostate cancer (HSPC) to lethal castration...
Proteomic analysis of plasma exosomes in patients with metastatic colorectal cancer
Proteomic analysis of plasma exosomes in patients with metastatic colorectal cancer
The diagnosis and treatment of colorectal cancer (CRC), especially metastatic colorectal cancer (mCRC), is a major priorit...
Identification of novel proteins in inflammatory bowel disease based on the gut-brain axis: a multi-omics integrated analysis
Identification of novel proteins in inflammatory bowel disease based on the gut-brain axis: a multi-omics integrated analysis
The gut-brain axis has garnered increasing attention, with observational studies suggesting its involvement in the disease...
SPOT: spatial proteomics through on-site tissue-protein-labeling
SPOT: spatial proteomics through on-site tissue-protein-labeling
Spatial proteomics seeks to understand the spatial organization of proteins in tissues or at different subcellular localiz...
Serum proteomics for the identification of biomarkers to flag predilection of COVID19 patients to various organ morbidities
Serum proteomics for the identification of biomarkers to flag predilection of COVID19 patients to various organ morbidities
COVID19 is a pandemic that has affected millions around the world since March 2020. While many patients recovered complete...
Changes in amino acid concentrations and the gut microbiota composition are implicated in the mucosal healing of ulcerative colitis and can be used as noninvasive diagnostic biomarkers
Changes in amino acid concentrations and the gut microbiota composition are implicated in the mucosal healing of ulcerative colitis and can be used as noninvasive diagnostic biomarkers
Mucosal healing is the therapeutic target for ulcerative colitis (UC). While amino acids (AAs) and the gut microbiota are ...
ESF1 and MIPEP proteins promote estrogen receptor-positive breast cancer proliferation and are associated with patient prognosis
ESF1 and MIPEP proteins promote estrogen receptor-positive breast cancer proliferation and are associated with patient prognosis
Estrogen receptor-positive (ER+) breast cancer accounts for two-thirds of all breast cancers, and its early and late recur...
Quantitative proteomics reveals serum proteome alterations during metastatic disease progression in breast cancer patients
Quantitative proteomics reveals serum proteome alterations during metastatic disease progression in breast cancer patients
Tumor recurrence and metastatic progression remains the leading cause for breast cancer related mortalities. However, the ...
Application of urine proteomics in the diagnosis and treatment effectiveness monitoring of early-stage Mycosis Fungoides
Application of urine proteomics in the diagnosis and treatment effectiveness monitoring of early-stage Mycosis Fungoides
Mycosis fungoides (MF) is the most common type of cutaneous T cell lymphoma. As the early clinical manifestations of MF ar...
Using established biorepositories for emerging research questions: a feasibility study
Using established biorepositories for emerging research questions: a feasibility study
Proteomics and metabolomics offer substantial potential for advancing kidney transplant research by providing versatile op...
Simultaneous targeted and discovery-driven clinical proteotyping using hybrid-PRM/DIA
Simultaneous targeted and discovery-driven clinical proteotyping using hybrid-PRM/DIA
Clinical samples are irreplaceable, and their transformation into searchable and reusable digital biobanks is critical for...
The relationship between serum astroglial and neuronal markers and AQP4 and MOG autoantibodies
The relationship between serum astroglial and neuronal markers and AQP4 and MOG autoantibodies
Certain demyelinating disorders, such as neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycopr...
Plasma proteomic characterization of colorectal cancer patients with FOLFOX chemotherapy by integrated proteomics technology
Plasma proteomic characterization of colorectal cancer patients with FOLFOX chemotherapy by integrated proteomics technology
Colorectal Cancer (CRC) is a prevalent form of cancer, and the effectiveness of the main postoperative chemotherapy treatm...
Proteomics study of primary and recurrent adamantinomatous craniopharyngiomas
Proteomics study of primary and recurrent adamantinomatous craniopharyngiomas
Adamantinomatous craniopharyngiomas (ACPs) are rare benign epithelial tumours with high recurrence and poor prognosis. Bio...
Multiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders
Multiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders
Cardio-metabolic disorders (CMDs) are common in aging people and are pivotal risk factors for cardiovascular diseases (CVD...
sBioSITe enables sensitive identification of the cell surface proteome through direct enrichment of biotinylated peptides
sBioSITe enables sensitive identification of the cell surface proteome through direct enrichment of biotinylated peptides
Cell surface proteins perform critical functions related to immune response, signal transduction, cell–cell interact...
Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissue
Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissue
Metabolic associated fatty liver disease (MAFLD) has become the most common chronic liver disease worldwide, and it is als...
Proteomic analysis of chromophobe renal cell carcinoma and benign renal oncocytoma biopsies reveals shared metabolic dysregulation
Proteomic analysis of chromophobe renal cell carcinoma and benign renal oncocytoma biopsies reveals shared metabolic dysregulation
This study investigates the proteomic landscapes of chromophobe renal cell carcinoma (chRCC) and renal oncocytomas (RO), t...
Validation of the novel GLAS algorithm as an aid in the detection of liver fibrosis and cirrhosis based on GP73, LG2m, age, and sex
Validation of the novel GLAS algorithm as an aid in the detection of liver fibrosis and cirrhosis based on GP73, LG2m, age, and sex
Diagnosis of liver disease at earlier stages can improve outcomes and reduce the risk of progression to malignancy. Liver ...
Development of a predictive model to distinguish prostate cancer from benign prostatic hyperplasia by integrating serum glycoproteomics and clinical variables
Development of a predictive model to distinguish prostate cancer from benign prostatic hyperplasia by integrating serum glycoproteomics and clinical variables
Prostate Cancer (PCa) represents the second leading cause of cancer-related death in men. Prostate-specific antigen (PSA) ...
Comparison of in-gel and in-solution proteolysis in the proteome profiling of organ perfusion solutions
Comparison of in-gel and in-solution proteolysis in the proteome profiling of organ perfusion solutions
The organ perfusion solution (perfusate), collected at clinically and temporally significant stages of the organ preservat...
Candidate biomarkers for treatment benefit from sunitinib in patients with advanced renal cell carcinoma using mass spectrometry-based (phospho)proteomics
Candidate biomarkers for treatment benefit from sunitinib in patients with advanced renal cell carcinoma using mass spectrometry-based (phospho)proteomics
The tyrosine kinase inhibitor sunitinib is an effective first-line treatment for patients with advanced renal cell carcino...
A pathway activity-based proteomic classifier stratifies prostate tumors into two subtypes
A pathway activity-based proteomic classifier stratifies prostate tumors into two subtypes
Prostate cancer (PCa) is the second most common cancer in males worldwide. The risk stratification of PCa is mainly based ...
Change of histone H3 lysine 14 acetylation stoichiometry in human monocyte derived macrophages as determined by MS-based absolute targeted quantitative proteomic approach: HIV infection and methamphetamine exposure
Change of histone H3 lysine 14 acetylation stoichiometry in human monocyte derived macrophages as determined by MS-based absolute targeted quantitative proteomic approach: HIV infection and methamphetamine exposure
Histones posttranslational modification represent an epigenetic mechanism that regulate gene expression and other cellular...
Comment on “Cerebrospinal fluid camk2a levels at baseline predict long-term progression in multiple sclerosis. Clinical Proteomics”
Comment on “Cerebrospinal fluid camk2a levels at baseline predict long-term progression in multiple sclerosis. Clinical Proteomics”
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Mass spectrometry quantifies target engagement for a KRASG12C inhibitor in FFPE tumor tissue
Mass spectrometry quantifies target engagement for a KRASG12C inhibitor in FFPE tumor tissue
Quantification of drug-target binding is critical for confirming that drugs reach their intended protein targets, understa...
Glial cell proteome using targeted quantitative methods for potential multi-diagnostic biomarkers
Glial cell proteome using targeted quantitative methods for potential multi-diagnostic biomarkers
Glioblastoma is one of the most malignant primary brain cancer. Despite surgical resection with modern technology followed...
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