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Identification of proteome-wide and functional analysis of lysine crotonylation in multiple organs of the human fetus
Identification of proteome-wide and functional analysis of lysine crotonylation in multiple organs of the human fetus
Lysine crotonylation (Kcr) is a novel post-translational modification that is important in functional studies. However, ou...
Identification of noval diagnostic biomarker for HFpEF based on proteomics and machine learning
Identification of noval diagnostic biomarker for HFpEF based on proteomics and machine learning
Heart failure with preserved ejection fraction (HFpEF) is a complex syndrome that currently lacks effective biomarkers for...
Plasma proteome analysis of rheumatic patients reveals differences in fingerprints based on cardiovascular history: a pilot study
Plasma proteome analysis of rheumatic patients reveals differences in fingerprints based on cardiovascular history: a pilot study
The risk of cardiovascular disease (CVD) in patients with rheumatoid arthritis (RA) is much higher than that in the genera...
Mass-spectrometry based metabolomics: an overview of workflows, strategies, data analysis and applications
Mass-spectrometry based metabolomics: an overview of workflows, strategies, data analysis and applications
Metabolomics, a burgeoning field within systems biology, focuses on the comprehensive study of small molecules present in ...
To explore the molecular mechanism of IRF7 involved in acute kidney injury in sepsis based on proteomics
To explore the molecular mechanism of IRF7 involved in acute kidney injury in sepsis based on proteomics
Acute kidney injury is a common complication of sepsis, and its mechanism is very complicated. The purpose of this study w...
Mechanism of the cardioprotective effect of empagliflozin on diabetic nephropathy mice based on the basis of proteomics
Mechanism of the cardioprotective effect of empagliflozin on diabetic nephropathy mice based on the basis of proteomics
Diabetic nephropathy affects a significant proportion of individuals with diabetes, and its progression often leads to car...
Genome-wide computational analysis of the dirigent gene family in Solanum lycopersicum
Genome-wide computational analysis of the dirigent gene family in Solanum lycopersicum
Dirigent (DIR) genes play a key role in the development of organic products in plants. They confer conformational influenc...
Multi-targeted olink proteomics analyses of cerebrospinal fluid from patients with aneurysmal subarachnoid hemorrhage
Multi-targeted olink proteomics analyses of cerebrospinal fluid from patients with aneurysmal subarachnoid hemorrhage
The complexity of delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH) may require the simultan...
Identification of mRNA biomarkers in extremely early hypertensive intracerebral hemorrhage (HICH)
Identification of mRNA biomarkers in extremely early hypertensive intracerebral hemorrhage (HICH)
Hypertensive intracerebral hemorrhage (HICH) stands out as a critical complication of primary hypertension. Consequently, ...
LC–MS-based quantitation of proteomic changes induced by Norcantharidin in MTB-Treated macrophages
LC–MS-based quantitation of proteomic changes induced by Norcantharidin in MTB-Treated macrophages
Tuberculosis drug resistance contributes to the spread of tuberculosis. Immunotherapy is an effective strategy for treatin...
Spatial proteomics: unveiling the multidimensional landscape of protein localization in human diseases
Spatial proteomics: unveiling the multidimensional landscape of protein localization in human diseases
Spatial proteomics is a multidimensional technique that studies the spatial distribution and function of proteins within c...
Methionine enkephalin (MENK) protected macrophages from ferroptosis by downregulating HMOX1 and ferritin
Methionine enkephalin (MENK) protected macrophages from ferroptosis by downregulating HMOX1 and ferritin
The aim of this work was to investigate the immunological effect of MENK by analyzing the protein spectrum and bioinformat...
Comparative proteomics reveals different protein expression in platelets in patients with alcoholic liver cirrhosis
Comparative proteomics reveals different protein expression in platelets in patients with alcoholic liver cirrhosis
The role of platelets in disease progression as well as the function of platelets as part of the haemostatic and immunolog...
Exosome proteomes reveal glycolysis-related enzyme enrichment in primary canine mammary gland tumor compared to metastases
Exosome proteomes reveal glycolysis-related enzyme enrichment in primary canine mammary gland tumor compared to metastases
Numerous evidence has highlighted the differences between primary tumors and metastases. Nonetheless, the differences in e...
A methodological exploration of distinguishing hair quality based on hair proteomics
A methodological exploration of distinguishing hair quality based on hair proteomics
Hair is an advantageous biological sample due to its recordable, collectable, and storable nature. Hair's primary comp...
iTRAQ-based proteomic study on monocyte cell model discovered an association of LAMP2 downregulation with HIV-1 latency
iTRAQ-based proteomic study on monocyte cell model discovered an association of LAMP2 downregulation with HIV-1 latency
Patients with immunodeficiency virus-1 (HIV-1) infection are challenging to be cured completely due to the existence of HI...
Upregulation of S100A8 in peripheral blood mononuclear cells from patients with depression treated with SSRIs: a pilot study
Upregulation of S100A8 in peripheral blood mononuclear cells from patients with depression treated with SSRIs: a pilot study
Major depressive disorder (MDD) affects more than 350 million people worldwide, and there is currently no laboratory test ...
Systematic proteomics profiling of lysine crotonylation of the lung at Pseudoglandular and Canalicular phases in human fetus
Systematic proteomics profiling of lysine crotonylation of the lung at Pseudoglandular and Canalicular phases in human fetus
Lung tissue is an important organ of the fetus, and genomic research on its development has improved our understanding of ...
TMT quantitative proteomics reveals key proteins relevant to microRNA-1-mediated regulation in osteoarthritis
TMT quantitative proteomics reveals key proteins relevant to microRNA-1-mediated regulation in osteoarthritis
Osteoarthritis (OA) is the second-commonest arthritis, but pathogenic and regulatory mechanisms underlying OA remain incom...
Quantitative proteomics analysis reveals the key proteins related to semen quality in Niangya yaks
Quantitative proteomics analysis reveals the key proteins related to semen quality in Niangya yaks
Proteins related to sperm motility and sperm morphology have an important impact on sperm function such as metabolism, mot...
Label-free quantitative proteomic analysis of serum exosomes in mice with thoracic aortic aneurysm
Label-free quantitative proteomic analysis of serum exosomes in mice with thoracic aortic aneurysm
Thoracic aortic aneurysm (TAA) is a cardiovascular disease with high morbidity and mortality. However, the causes and mech...
Integrated proteome and malonylome analyses reveal the potential meaning of TLN1 and ACTB in end-stage renal disease
Integrated proteome and malonylome analyses reveal the potential meaning of TLN1 and ACTB in end-stage renal disease
End-stage renal disease (ESRD) is a condition that is characterized by the loss of kidney function. ESRD patients suffer f...
Proteomic analysis of neonatal mouse hearts shows PKA functions as a cardiomyocyte replication regulator
Proteomic analysis of neonatal mouse hearts shows PKA functions as a cardiomyocyte replication regulator
The ability of the adult mammalian heart to regenerate can save the cardiac muscle from a loss of function caused by injur...
Effects of µ-Conotoxin GIIIB on the cellular activity of mouse skeletal musculoblast: combined transcriptome and proteome analysis
Effects of µ-Conotoxin GIIIB on the cellular activity of mouse skeletal musculoblast: combined transcriptome and proteome analysis
µ-Conotoxin GIIIB (µ-CTX GIIIB) is a polypeptide containing three disulfide bridges, produced by the sea snail C...
Proteomic analysis of ceftazidime and meropenem-exposed Pseudomonas aeruginosa ATCC 9027
Proteomic analysis of ceftazidime and meropenem-exposed Pseudomonas aeruginosa ATCC 9027
Pseudomonas aeruginosa is well known for its intrinsic ability to resist a wide range of antibiotics, thus complicates tre...
Analysis of differential membrane proteins related to matrix stiffness-mediated metformin resistance in hepatocellular carcinoma cells
Analysis of differential membrane proteins related to matrix stiffness-mediated metformin resistance in hepatocellular carcinoma cells
Our previous work shows that increased matrix stiffness not only alters malignant characteristics of hepatocellular carcin...
Insight into the underlying molecular mechanism of dilated cardiomyopathy through integrative analysis of data mining, iTRAQ-PRM proteomics and bioinformatics
Insight into the underlying molecular mechanism of dilated cardiomyopathy through integrative analysis of data mining, iTRAQ-PRM proteomics and bioinformatics
DCM is a common cardiomyopathy worldwide, which is characterized by ventricular dilatation and systolic dysfunction. DCM i...
PRM-based quantitative proteomics analysis of altered HSP abundance in villi and decidua of patients with early missed abortion
PRM-based quantitative proteomics analysis of altered HSP abundance in villi and decidua of patients with early missed abortion
In this study, we aimed to identify differentially expressed heat shock protein (HSP) profiles in the villi and decidua fr...
Serum proteomic identification and validation of two novel atherosclerotic aortic aneurysm biomarkers, profilin 1 and complement factor D
Serum proteomic identification and validation of two novel atherosclerotic aortic aneurysm biomarkers, profilin 1 and complement factor D
Effective diagnostic biomarkers for aortic aneurysm (AA) that are detectable in blood tests are required because early det...
Altered levels of transthyretin in human cerebral microdialysate after subarachnoid haemorrhage using proteomics; a descriptive pilot study
Altered levels of transthyretin in human cerebral microdialysate after subarachnoid haemorrhage using proteomics; a descriptive pilot study
Subarachnoid haemorrhage (SAH) is one of the most severe forms of stroke in which delayed cerebral ischemia is one of the ...
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