Bagcchi S. Who’s global tuberculosis report 2022. Lancet Microb. 2023;4(1):e20.
Alvarez AH, Flores-Valdez MA. Can immunization with bacillus calmette-guerin be improved for prevention or therapy and elimination of chronic mycobacterium tuberculosis infection? Expert Rev Vaccines. 2019;18(12):1219–27.
Article CAS PubMed Google Scholar
Lovey A, Verma S, Kaipilyawar V, et al. Early alveolar macrophage response and il-1r-dependent t cell priming determine transmissibility of mycobacterium tuberculosis strains. Nat Commun. 2022;13(1):884.
Article CAS PubMed PubMed Central Google Scholar
Paik S, Kim KT, Kim IS, et al. Mycobacterial acyl carrier protein suppresses tfeb activation and upregulates mir-155 to inhibit host defense. Front Immunol. 2022;13:946929.
Article CAS PubMed PubMed Central Google Scholar
Su H, Zhu S, Zhu L, et al. Recombinant lipoprotein rv1016c derived from mycobacterium tuberculosis is a tlr-2 ligand that induces macrophages apoptosis and inhibits mhc ii antigen processing. Front Cell Infect Microbiol. 2016;6:147.
Article PubMed PubMed Central Google Scholar
Hwang SA, Ali Y, Fedotova E, et al. Morphoproteomics identifies the foamy alveolar macrophage as an m2 phenotype with pd-l1 expression in the early lesion of post-primary tuberculosis: Implications for host immune surveillance and therapy. Ann Clin Lab Sci. 2020;50(4):429–38.
Wang L, Otkur W, Wang A, et al. Norcantharidin overcomes vemurafenib resistance in melanoma by inhibiting pentose phosphate pathway and lipogenesis via downregulating the mtor pathway. Front Pharmacol. 2022;13:906043.
Article CAS PubMed PubMed Central Google Scholar
Wei M, Jiang Y, Sun R, et al. Self-assembly of a linear-dendritic polymer containing cisplatin and norcantharidin into raspberry-like multimicelle clusters for the efficient chemotherapy of liver cancer. ACS Appl Mater Interfaces. 2023;15(11):14664–77.
Zhai BT, Sun J, Shi YJ, et al. Review targeted drug delivery systems for norcantharidin in cancer therapy. J Nanobiotechnology. 2022;20(1):509.
Article PubMed PubMed Central Google Scholar
Xiao S, Wang Y, Ma W, et al. Intraperitoneal administration of thermosensitive hydrogel co-loaded with norcantharidin nanoparticles and oxaliplatin inhibits malignant ascites of hepatocellular carcinoma. Drug Delivery. 2022;29(1):2713–22.
Article CAS PubMed PubMed Central Google Scholar
Zhou J, Ren Y, Tan L, et al. Norcantharidin: Research advances in pharmaceutical activities and derivatives in recent years. Biomed Pharmacother. 2020;131:110755.
Article CAS PubMed Google Scholar
Zhao Q, Qian Y, Li R, et al. Norcantharidin facilitates lps-mediated immune responses by up-regulation of akt/nf-kappab signaling in macrophages. PLoS ONE. 2012;7(9):e44956.
Article CAS PubMed PubMed Central Google Scholar
Liu XH, Blazsek I, Comisso M, et al. Effects of norcantharidin, a protein phosphatase type-2a inhibitor, on the growth of normal and malignant haemopoietic cells. Eur J Cancer. 1995;31A(6):953–63.
Article CAS PubMed Google Scholar
Zheng J, Qian ZM, Sun YX, et al. Downregulation of hepcidin by norcantharidin in macrophage. Nat Prod Res. 2023;38(4):1–6.
Zheng J, Wang JJ, Ma HM, et al. Norcantharidin down-regulates iron contents in the liver and spleen of lipopolysaccharide-treated mice. Redox Rep. 2022;27(1):119–27.
Article CAS PubMed PubMed Central Google Scholar
Han Z, Li B, Wang J, et al. Norcantharidin inhibits sk-n-sh neuroblastoma cell growth by induction of autophagy and apoptosis [J]. Technol Cancer Res Treat. 2017;16(1):33–44.
Article CAS PubMed Google Scholar
Du LJ, Feng YX, He ZX, et al. Norcantharidin ameliorates the development of murine lupus via inhibiting the generation of il-17 producing cells. Acta Pharmacol Sin. 2022;43(6):1521–33.
Article CAS PubMed Google Scholar
Qiu P, Wang S, Liu M, et al. Norcantharidin inhibits cell growth by suppressing the expression and phosphorylation of both egfr and c-met in human colon cancer cells. BMC Cancer. 2017;17(1):55.
Article PubMed PubMed Central Google Scholar
Zhang Z, Sun B, Lu J, et al. Norcantharidin inhibits the malignant progression of cervical cancer by inducing endoplasmic reticulum stress. Mol Med Rep. 2024;29(5):71.
Article CAS PubMed PubMed Central Google Scholar
Li XP, Jing W, Sun JJ, et al. A potential small-molecule synthetic antilymphangiogenic agent norcantharidin inhibits tumor growth and lymphangiogenesis of human colonic adenocarcinomas through blocking vegf-a,-c,-d/vegfr-2,-3 “multi-points priming” mechanisms in vitro and in vivo. BMC Cancer. 2015;15:527.
Article PubMed PubMed Central Google Scholar
Gao Y, Li W, Liu R, et al. Norcantharidin inhibits il-6-induced epithelial-mesenchymal transition via the jak2/stat3/twist signaling pathway in hepatocellular carcinoma cells. Oncol Rep. 2017;38(2):1224–32.
Article CAS PubMed Google Scholar
Chen YC, Chang SC, Wu MH, et al. Norcantharidin reduced cyclins and cytokines production in human peripheral blood mononuclear cells. Life Sci. 2009;84(7–8):218–26.
Article CAS PubMed Google Scholar
Li B, Wang W, Zhao L, et al. Photothermal therapy of tuberculosis using targeting pre-activated macrophage membrane-coated nanoparticles. Nat Nanotechnol. 2024;19(6):834–45.
Article CAS PubMed Google Scholar
Gupta A, Thirunavukkarasu S, Rangel-Moreno J, et al. Phospholipase c epsilon-1 (plce1) mediates macrophage activation and protection against tuberculosis. Infect Immun. 2024;92(4):e0049523.
Park JY, Kim HD, Abekura F, et al. A novel mycobacterium tuberculosis antigen, mtb48 enhances inflammatory response in lps-induced raw 264.7 macrophage immune cells. Mol Immunol. 2024;166:50–7.
Article CAS PubMed Google Scholar
Mwebaza I, Shaw R, Li Q, et al. Impact of mycobacterium tuberculosis glycolipids on the cd4+ t cell-macrophage immunological synapse. J Immunol. 2023;211(9):1385–96.
Article CAS PubMed PubMed Central Google Scholar
Ge B. Mycobacterium tuberculosis suppresses host DNA repair to boost its intracellular survival. Cell Host Microbe. 2023;2023(31):1–17.
Bedard M, van der Niet S, Bernard EM, et al. A terpene nucleoside from m. Tuberculosis induces lysosomal lipid storage in foamy macrophages. J Clin Invest. 2023;133(6):e161944.
Article CAS PubMed PubMed Central Google Scholar
Maglione PJ, Xu J, Casadevall A, et al. Fc gamma receptors regulate immune activation and susceptibility during mycobacterium tuberculosis infection [J]. J Immunol. 2008;180(5):3329–38.
Article CAS PubMed Google Scholar
Cox DJ, Coleman AM, Gogan KM, et al. Inhibiting histone deacetylases in human macrophages promotes glycolysis, il-1beta, and t helper cell responses to mycobacterium tuberculosis. Front Immunol. 2020;11:1609.
Article CAS PubMed PubMed Central Google Scholar
Zhang S, Zhou X, Ou M, et al. Berbamine promotes macrophage autophagy to clear mycobacterium tuberculosis by regulating the ros/ca(2+) axis. mBio. 2023;14(4):e0027223.
Gupta PK, Jahagirdar P, Tripathi D, et al. Macrophage targeted polymeric curcumin nanoparticles limit intracellular survival of mycobacterium tuberculosis through induction of autophagy and augment anti-tb activity of isoniazid in raw 264.7 macrophages. Front Immunol. 2023;14:1233630.
Comments (0)