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A novel tramadol–polycaprolactone implant could palliate heroin conditioned place preference and withdrawal in rats: behavioral and neurochemical study
A novel tramadol–polycaprolactone implant could palliate heroin conditioned place preference and withdrawal in rats: behavioral and neurochemical study
Drug dependence is a chronic brain disease characterized by craving and recurrent episodes of relaps
Opioid receptor antagonists reduce motivated wheel-running behavior in mice
Opioid receptor antagonists reduce motivated wheel-running behavior in mice
We hypothesized that opioid receptor antagonists would inhibit motivated behavior produced by a natu
Neuronal nicotinic acetylcholine receptor of the central amygdala modulates the ethanol-induced tolerance to anxiolysis and withdrawal-induced anxiety in male rats
Neuronal nicotinic acetylcholine receptor of the central amygdala modulates the ethanol-induced tolerance to anxiolysis and withdrawal-induced anxiety in male rats
The nicotine acetylcholinergic receptor (nAchR) in the central nucleus of the amygdala (CeA) is know
Intra-accumbal orexinergic system contributes to the stress-induced antinociceptive behaviors in the animal model of acute pain in rats
Intra-accumbal orexinergic system contributes to the stress-induced antinociceptive behaviors in the animal model of acute pain in rats
Stress and pain are interleaved at numerous levels - influencing each other. Stress can increase the
Positive modulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors differentially alters spatial learning and memory in juvenile rats younger and older than three weeks
Positive modulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors differentially alters spatial learning and memory in juvenile rats younger and older than three weeks
Remarkable performance improvements occur at the end of the third postnatal week in rodents tested i
Contingency learning in zebrafish exposed to apomorphine- and levetiracetam
Contingency learning in zebrafish exposed to apomorphine- and levetiracetam
Cognitive rigidity (CR) refers to inadequate executive adaptation in the face of changing circumstan
Heterozygous and homozygous gene knockout of the 5-HT1B receptor have different effects on methamphetamine-induced behavioral sensitization
Heterozygous and homozygous gene knockout of the 5-HT1B receptor have different effects on methamphetamine-induced behavioral sensitization
The psychostimulant drug methamphetamine (METH) causes euphoria in humans and locomotor hyperactivit
Anorectic effect of COR659 in a rat model of overeating
Anorectic effect of COR659 in a rat model of overeating
COR659 is a new compound, the action of which is exerted via a dual mechanism: positive allosteric m
Can we change automatic processes: the influence of social priming on alcohol attentional bias
Can we change automatic processes: the influence of social priming on alcohol attentional bias
The Stroop Effect has been linked to social concept priming, suggesting that the latter may trigger
Serial feature positive and feature negative discrimination learning in a taste avoidance preparation: implications for interoceptive control of behavior
Serial feature positive and feature negative discrimination learning in a taste avoidance preparation: implications for interoceptive control of behavior
Background Psychoactive drugs produce interoceptive stimuli that can guide appropriate behaviors
Liver tryptophan 2,3-dioxygenase: a determinant of anxiety-like behaviour – studies with chronic nicotine administration in rats
Liver tryptophan 2,3-dioxygenase: a determinant of anxiety-like behaviour – studies with chronic nicotine administration in rats
Deletion of the tryptophan 2,3-dioxygenase (TDO2) gene induces an anxiolytic-like behaviour in mice
The mGlu2/3 agonist LY379268 reduces sucrose taking, seeking, and motivation in male and female rats
The mGlu2/3 agonist LY379268 reduces sucrose taking, seeking, and motivation in male and female rats
Objectives The mGlu2/3 receptor agonist LY379268 reduces sucrose-seeking, but not sucrose-taking,
Creatine supplementation protects spatial memory and long-term potentiation against chronic restraint stress
Creatine supplementation protects spatial memory and long-term potentiation against chronic restraint stress
Stress contributes to numerous psychopathologies, including memory impairment, and threatens one’s w
Propranolol blocks the unconditioned and conditioned hyperactive effects of methamphetamine in CD-1 mice
Propranolol blocks the unconditioned and conditioned hyperactive effects of methamphetamine in CD-1 mice
The present experiment examined the contribution of the β-adrenergic receptor system in mediating th
Zymosan A produces a rapid and sustained antidepressant effect in chronically stressed mice by stimulating hippocampal microglia
Zymosan A produces a rapid and sustained antidepressant effect in chronically stressed mice by stimulating hippocampal microglia
Recent studies had reported that compounds that stimulate microglia could be developed as potential
Estradiol enhances the mirtazapine effects on the expression of cocaine-induced locomotor sensitization in female rats
Estradiol enhances the mirtazapine effects on the expression of cocaine-induced locomotor sensitization in female rats
Epidemiological studies have mentioned that cocaine use disorder (CUD) has increased in the last dec
Use of drug purchase tasks in medications development research: orexin system regulation of cocaine and drug demand
Use of drug purchase tasks in medications development research: orexin system regulation of cocaine and drug demand
Commodity purchase tasks provide a useful method for evaluating behavioral economic demand in the hu
The M1-muscarinic acetylcholine receptor subtype may play a role in learning and memory performance in the hippocampus of neonatal monosodium glutamate-obese rats
The M1-muscarinic acetylcholine receptor subtype may play a role in learning and memory performance in the hippocampus of neonatal monosodium glutamate-obese rats
Here, we investigate the effects of obesity induced by monosodium glutamate (MSG) on cognitive impai
Effect of l-Dopa in acute temozolomide-induced cognitive impairment in male mice: a possible antineuroinflammatory role
Effect of l-Dopa in acute temozolomide-induced cognitive impairment in male mice: a possible antineuroinflammatory role
Temozolomide is used commonly in the treatment of some types of cancers, but it may also result in c
Menstrual cycle influences on cue-induced smoking cravings and heart rate variability
Menstrual cycle influences on cue-induced smoking cravings and heart rate variability
Women experience greater difficulties in quitting smoking than men, though the hormonal factors cont
Agmatine prevents the memory impairment and the dysfunction of hippocampal GSK-3β and ERK signaling induced by aluminum nanoparticle in mice
Agmatine prevents the memory impairment and the dysfunction of hippocampal GSK-3β and ERK signaling induced by aluminum nanoparticle in mice
The growing usage of aluminum nanoparticles (Al-NP) and their exposure may influence body function.
The role of lateral habenula NMDA receptors in tramadol-induced conditioning
The role of lateral habenula NMDA receptors in tramadol-induced conditioning
The role of the lateral habenula (LHb) as a hub for receiving and relaying signals from the limbic s
Pharmacological evaluation of lateral habenula and rostromedial tegmental nucleus in the expression of ethanol-induced place preference
Pharmacological evaluation of lateral habenula and rostromedial tegmental nucleus in the expression of ethanol-induced place preference
Although ethanol administration produces a range of physiological effects, the rewarding aspect asso
The effect of early and long-term propranolol therapy on learning and memory in mice
The effect of early and long-term propranolol therapy on learning and memory in mice
Propranolol is the treatment of choice for infantile hemangioma. We investigated the effects of long
Behavioral effects induced by the cannabidiol analogs HU-502 and HU-556
Behavioral effects induced by the cannabidiol analogs HU-502 and HU-556
Cannabidiol is a phytocannabinoid that lacks the psychotomimetic properties of Δ9-tetrahydrocannabin
Maternal treatment with aripiprazole prevents the development of a valproic acid-induced autism-like phenotype in juvenile male mice
Maternal treatment with aripiprazole prevents the development of a valproic acid-induced autism-like phenotype in juvenile male mice
Autism spectrum disorder (ASD) describes a heterogeneous group of neurodevelopmental conditions char
Announcement of two Special Issues:‘Behavioural pharmacology of pain’ and ‘Sex differences in behavioural pharmacology’
Announcement of two Special Issues:‘Behavioural pharmacology of pain’ and ‘Sex differences in behavioural pharmacology’
Pain (Spring 2024) Pain is as diverse as it is ubiquitous. It is perhaps the health condition that most people ...
Long-term follow-up of intracerebroventricular injection of streptozotocin-inducing pain sensitization
Long-term follow-up of intracerebroventricular injection of streptozotocin-inducing pain sensitization
Age is known to be the major risk factor for both pain sensation and sporadic Alzheimer’s disease (s
Aldehyde dehydrogenase 2–associated changes in pharmacokinetics, locomotor function and peripheral glutamic acid and gamma-aminobutyric acid levels during acute alcohol intoxication in male mice
Aldehyde dehydrogenase 2–associated changes in pharmacokinetics, locomotor function and peripheral glutamic acid and gamma-aminobutyric acid levels during acute alcohol intoxication in male mice
The insufficiency of human aldehyde dehydrogenase 2 (ALDH2) has been consistently associated with hi
Preclinical comparison of antinociceptive effects between ibuprofen, diclofenac, naproxen, and acetaminophen on acid-stimulated body stretching and acid-depressed feeding behaviors in rats
Preclinical comparison of antinociceptive effects between ibuprofen, diclofenac, naproxen, and acetaminophen on acid-stimulated body stretching and acid-depressed feeding behaviors in rats
Pain is a major problem that burdens the health and economy of societies worldwide. Nonsteroidal ant
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