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The Impact of Obesity on Pressure–Volume Relationship in Ambulatory Heart Failure
The Impact of Obesity on Pressure–Volume Relationship in Ambulatory Heart Failure
Assessment of volume status is essential in heart failure (HF) management, yet the relationship between cardiac filling pr...
Machine Learning-based Prediction of Temporal Velocity-Informatics (TVI) Variables for Accelerated Characterization of Intracranial Aneurysms’ Rupture Status
Machine Learning-based Prediction of Temporal Velocity-Informatics (TVI) Variables for Accelerated Characterization of Intracranial Aneurysms’ Rupture Status
Temporal velocity-informatics (TVI) is a novel technique utilizing spatial analysis of time-resolved 3D velocity fields to...
Preclinical Assessment of a Novel Polymer-Free Hybrid Drug Eluting Stent
Preclinical Assessment of a Novel Polymer-Free Hybrid Drug Eluting Stent
We aimed to evaluate a novel polymer-free hybrid drug eluting stent (DES) relative to benchmark devices and speci...
Roles of Long Non-Coding RNAs in the Pathogenesis of Cardiovascular Disorders: Challenges and Opportunities
Roles of Long Non-Coding RNAs in the Pathogenesis of Cardiovascular Disorders: Challenges and Opportunities
Cardiovascular disease (CVD) is a prominent contributor to global mortality rates, and its prevalence is consistently on t...
Reprogramming of Mitochondrial and Cellular Energy Metabolism in Fibroblasts and Cardiomyocytes: Mechanisms and Therapeutic Strategies in Cardiac Fibrosis
Reprogramming of Mitochondrial and Cellular Energy Metabolism in Fibroblasts and Cardiomyocytes: Mechanisms and Therapeutic Strategies in Cardiac Fibrosis
Cardiac fibrosis, marked by excessive extracellular matrix accumulation, is a key endpoint in various cardiac diseases and...
VEGFR1 as a Target for Cardiovascular Gene Therapy
VEGFR1 as a Target for Cardiovascular Gene Therapy
Vascular endothelial growth factor receptor 1 (VEGFR1) is a key regulator of endothelial function, angiogenesis, inflammat...
Advances in Acute Myocardial Infarction (AMI) Diagnostics: Classical Biomarkers, Emerging Tools, and the Rise of Non-Invasive Sampling
Advances in Acute Myocardial Infarction (AMI) Diagnostics: Classical Biomarkers, Emerging Tools, and the Rise of Non-Invasive Sampling
Acute myocardial infarction (AMI) remains a leading cause of mortality worldwide, highlighting the need for improved diagn...
Platelet Reactivity and Fibrin Clot-Strength as assessed by TEG in Patients with Atrial Fibrillation undergoing Percutaneous Coronary Intervention
Platelet Reactivity and Fibrin Clot-Strength as assessed by TEG in Patients with Atrial Fibrillation undergoing Percutaneous Coronary Intervention
Platelet reactivity (PR) in clopidogrel-treated patients undergoing percutaneous coronary syndrome (PCI) associat...
Diammonium Glycyrrhizinate Alleviated Myocardial Fibrosis Induced by Isoprenaline Via Modulation of STAT/Smad3 Pathway
Diammonium Glycyrrhizinate Alleviated Myocardial Fibrosis Induced by Isoprenaline Via Modulation of STAT/Smad3 Pathway
Myocardial fibrosis (MF) severely impairs the heart structure and function post-myocardial infarction. The study investiga...
Characterization of Neutrophil Extracellular Traps in Acute Myocardial Infarction: A Translational Study
Characterization of Neutrophil Extracellular Traps in Acute Myocardial Infarction: A Translational Study
Neutrophil extracellular traps (NETs) are implicated in thrombosis and inflammation during acute myocardial infarction (AM...
Long Non-coding RNA Based Therapy for Cardiovascular Disease
Long Non-coding RNA Based Therapy for Cardiovascular Disease
Cardiovascular diseases (CVDs) remain a leading cause of morbidity and mortality worldwide, necessitating innovative thera...
The Use of the Medina Coronary Bifurcation Classification has Led to Confusion and Missing One Third of True Bifurcation Lesions. The Movahed Bifurcation Classification Should be the Preferred Classification as it Categorizes All True Bifurcation Lesions in One Simple Category B2 Lesions with Limitless Suffixes that Can be Added if Needed
The Use of the Medina Coronary Bifurcation Classification has Led to Confusion and Missing One Third of True Bifurcation Lesions. The Movahed Bifurcation Classification Should be the Preferred Classification as it Categorizes All True Bifurcation Lesions in One Simple Category B2 Lesions with Limitless Suffixes that Can be Added if Needed
Rahimi F, Löffelhardt N, Minners J, Breitbart P, Franke K, Hartikainen TS, Valina C, Mühlen CVZ, Nührenberg T, Kastrati A,...
Circulating as a Diagnostic Biomarker of Early Endothelial Dysfunction in Young Dyslipidemic Individuals
Circulating as a Diagnostic Biomarker of Early Endothelial Dysfunction in Young Dyslipidemic Individuals
Diagnostic potential of sialin in identifying endothelial dysfunction is explored. 50 CAD patients, 50 young (20–35&...
Cardioplegic Machine Perfusion of Hearts Donated after Circulatory Death
Cardioplegic Machine Perfusion of Hearts Donated after Circulatory Death
We compared the effects of ex-vivo machine perfusion (EVMP) of hearts donated after circulatory death (DCD) with the singl...
Hypoxia Aggravates Myocardial Ischemia/Reperfusion Injury Through the Promotion of Ferroptosis via ACSL4 Lactylation
Hypoxia Aggravates Myocardial Ischemia/Reperfusion Injury Through the Promotion of Ferroptosis via ACSL4 Lactylation
Myocardial ischemia/reperfusion injury (MIRI) worsens ischemic damage, with ferroptosis as a key mediator of this iron-dep...
Network Medicine-Based Repurposing of Mesalazine for Atherosclerosis Treatment
Network Medicine-Based Repurposing of Mesalazine for Atherosclerosis Treatment
Atherosclerosis remains a leading cause of cardiovascular disease and mortality worldwide, despite advancements in statin ...
Maternal diet shapes infant microbiota and defensive capacity against infections in early life via differential human milk composition
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Rapid, sensitive, and species-independent detection of Crimean Congo hemorrhagic fever virus nucleoprotein and GP38 antibodies
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The effect of amycretin, a unimolecular glucagon-like peptide-1 and amylin receptor agonist, on body weight and metabolic dysfunction in mice and rats
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The sodium-glutamate antagonist riluzole improves outcome after acute spinal cord injury: results from the RISCIS randomised controlled trial analysed using a global statistical analytic technique
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Quantitative lung ultrasound to guide surfactant retreatment in preterm neonates born at ≤30 weeks’ gestation: a multicentre retrospective non-inferiority diagnostic accuracy study
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The association between circulating SIGLEC6 and preeclampsia: observational studies of seven cohorts
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Post COVID 19 resurgence of diphtheria in Kano, Nigeria: analysis of 18,320 cases
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Plasma proteomic signatures of dual cognitive and mobility decline in older adults
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Discovery and validation of biomarkers for Parkinson’s disease from human cerebrospinal fluid using mass spectrometry-based proteomics analysis
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Artificial intelligence for prediction of atrial fibrillation in the stroke unit: a retrospective derivation validation cohort study
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HLA-A∗03:01 as predictive genetic biomarker for glatiramer acetate treatment response in multiple sclerosis: a retrospective cohort analysis
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Tandem CD19/CD22 CAR T-cells as potential therapy for children and young adults with high-risk r/r B-ALL
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Skeletal muscle, neuromuscular organoids and assembloids: a scoping review
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Viral and non-viral vectors in gene therapy: current state and clinical perspectives
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