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Embracing an era of targeted combination therapy for heart failure with preserved ejection fraction
Embracing an era of targeted combination therapy for heart failure with preserved ejection fraction
The concept of quadruple therapy as a "one-size-fit-all" approach is effective among all eligible patients with ...
Artificial intelligence and myocarditis—a systematic review of current applications
Artificial intelligence and myocarditis—a systematic review of current applications
Myocarditis, marked by heart muscle inflammation, poses significant clinical challenges. This study, guided by PRISMA guid...
Contemporary clinical role of echocardiography in patients with advanced heart failure
Contemporary clinical role of echocardiography in patients with advanced heart failure
Echocardiography represents an essential tool for imagers and clinical cardiologists in the management of patients with he...
Pharmacological management of heart failure in adults with congenital heart disease
Pharmacological management of heart failure in adults with congenital heart disease
Congenital heart disease (CHD) is the most common global congenital defect affecting over 2.4 million individuals in the U...
Treating heart failure by targeting the vagus nerve
Treating heart failure by targeting the vagus nerve
Increased sympathetic and reduced parasympathetic nerve activity is associated with disease progression and poor outcomes ...
Peripartum cardiomyopathy: a comprehensive and contemporary review
Peripartum cardiomyopathy: a comprehensive and contemporary review
Cardiovascular disease is a major non-communicable disease globally, with increasing prevalence, posing a significant publ...
Clinical and utilization outcomes with short stay units vs hospital admission for lower risk decompensated heart failure: a systematic review and meta-analysis
Clinical and utilization outcomes with short stay units vs hospital admission for lower risk decompensated heart failure: a systematic review and meta-analysis
With over 1 million primary heart failure (HF) hospitalizations annually, nearly 80% of patients who present to the emerge...
Congestion/decongestion in heart failure: what does it mean, how do we assess it, and what are we missing?—is there utility in measuring volume?
Congestion/decongestion in heart failure: what does it mean, how do we assess it, and what are we missing?—is there utility in measuring volume?
Clinical congestion remains a major cause of hospitalization and re-hospitalizations in patients with chronic heart failur...
Adrenal crisis-induced cardiogenic shock (ACCS): a comprehensive review
Adrenal crisis-induced cardiogenic shock (ACCS): a comprehensive review
Adrenal insufficiency (AI) is a disorder in which inadequate glucocorticoid and mineralocorticoid hormone production leads...
The road to renal denervation for hypertension and beyond (HF): two decades of failed, succeeded, and to be determined
The road to renal denervation for hypertension and beyond (HF): two decades of failed, succeeded, and to be determined
Activation of the sympathetic nervous system has been attributed to the development of hypertension. Two established appro...
Sodium-glucose co-transporter 2 inhibitors in left ventricular assist device and heart transplant recipients: a mini-review
Sodium-glucose co-transporter 2 inhibitors in left ventricular assist device and heart transplant recipients: a mini-review
In recent years, sodium-glucose co-transporter 2 inhibitors (SGLT2i) emerged as promising therapeutic agents in managing h...
Diagnosis and management of hypertrophic cardiomyopathy: European vs. American guidelines
Diagnosis and management of hypertrophic cardiomyopathy: European vs. American guidelines
Hypertrophic cardiomyopathy (HCM) is the most common genetic heart disease, affecting 1:200 to 1:500 individuals worldwide...
Maternal heart failure: state-of-the-art review
Maternal heart failure: state-of-the-art review
Pregnancy is a period of substantial changes to the body’s normal physiology, and the failure to adapt to these chan...
Could SGLT2 inhibitors improve outcomes in patients with heart failure and significant valvular heart disease? Need for action
Could SGLT2 inhibitors improve outcomes in patients with heart failure and significant valvular heart disease? Need for action
Delivering valvular intervention for all eligible patients with valvular heart disease (VHD) in a timely manner remains a ...
Epigenetics of cardiomyopathies: the next frontier
Epigenetics of cardiomyopathies: the next frontier
Cardiomyopathies (CMP) are a diverse group of myocardial diseases that cause structural, functional, and pathological chan...
Hyperkalemia management: a multidisciplinary expert panel’s perspective on the role of new potassium binders
Hyperkalemia management: a multidisciplinary expert panel’s perspective on the role of new potassium binders
Hyperkalemia is a potentially life-threatening condition frequently encountered in clinical practice, particularly among p...
Potential effects of beta-blockers in HFpEF
Potential effects of beta-blockers in HFpEF
Heart failure with preserved ejection fraction (HFpEF) poses a significant challenge in contemporary medicine, characteriz...
A causal association between chemokines and the risk of lung cancer: a univariate and multivariate mendelian randomization study
A causal association between chemokines and the risk of lung cancer: a univariate and multivariate mendelian randomization study
Observational studies and experimental evidence have shown that chemokines play important roles in lung cancer development...
Prognostic impact of the metabolic syndrome and its components in acute type a aortic dissection after surgery: a retrospective study
Prognostic impact of the metabolic syndrome and its components in acute type a aortic dissection after surgery: a retrospective study
This study aimed to explore whether metabolic syndrome (MetS) and its components are associated with poor outcomes in pati...
LncRNA CASC9 facilitates papillary thyroid cancer development and doxorubicin resistance via miR-28-3p/BCL-2 axis and PI3K/AKT signaling pathway
LncRNA CASC9 facilitates papillary thyroid cancer development and doxorubicin resistance via miR-28-3p/BCL-2 axis and PI3K/AKT signaling pathway
Papillary thyroid cancer (PTC) is a malignant tumor that poses a serious threat to human health. LncRNA CASC9 serves as an...
The effect of cardiac rehabilitation prescription on medication complications and ET-1, WMSI in elderly patients with coronary heart disease
The effect of cardiac rehabilitation prescription on medication complications and ET-1, WMSI in elderly patients with coronary heart disease
To explore the effects of cardiac rehabilitation prescriptions on medication complications, Endothelin 1 (ET-1), and Wall ...
National outcomes for dementia patients undergoing cardiac surgery in a pre-structural era
National outcomes for dementia patients undergoing cardiac surgery in a pre-structural era
With an aging population and higher prevalence of dementia, there is a paucity of data regarding dementia patients undergo...
Interplay of the heart, spleen, and bone marrow in heart failure: the role of splenic extramedullary hematopoiesis
Interplay of the heart, spleen, and bone marrow in heart failure: the role of splenic extramedullary hematopoiesis
Improvements in therapies for heart failure with preserved ejection fraction (HFpEF) are crucial for improving patient out...
Biosensors with left ventricular assist devices
Biosensors with left ventricular assist devices
Heart failure imposes a significant global health burden, standing as a primary contributor to mortality. Various indicato...
STEP HFpEF DM: a sweet sequel
STEP HFpEF DM: a sweet sequel
Kosiborod MN, Petrie MC, Borlaug BA et al (2024) Semaglutide in patients with obesity-related heart failure and type 2 dia...
Selective aldose reductase inhibition as a treatment for diabetic cardiomyopathy: summary of the ARISE-HF trial
Selective aldose reductase inhibition as a treatment for diabetic cardiomyopathy: summary of the ARISE-HF trial
Conflict of interest Drs. MS Khan, Ambrosy, and Greene are ...
Evaluating the role of interatrial shunt devices in heart failure management: insights from the RELIEVE-HF trial
Evaluating the role of interatrial shunt devices in heart failure management: insights from the RELIEVE-HF trial
McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M et al (2021) 2021 ESC Guidelines for the diagnosis and treat...
Extended thromboprophylaxis in heart failure patients; the unmet need
Extended thromboprophylaxis in heart failure patients; the unmet need
Heart failure (HF) is considered one of a leading cause of cardiovascular morbidity and mortality worldwide. The associati...
New insights gained from cellular landscape changes in myocarditis and inflammatory cardiomyopathy
New insights gained from cellular landscape changes in myocarditis and inflammatory cardiomyopathy
Advances in the etiological classification of myocarditis and inflammatory cardiomyopathy (ICM) have reached a consensus. ...
High-intensity care for GDMT titration
High-intensity care for GDMT titration
Heart failure (HF) is a systemic disease associated with a high risk of morbidity, mortality, increased risk of hospitaliz...
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