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Perifollicular concentric granulomas: A clue to IgG4-related lymphadenopathy
Perifollicular concentric granulomas: A clue to IgG4-related lymphadenopathy
A 69-year-old with well-controlled HIV was evaluated for persistent cough, in the context of years of fatigue and...
Follicular dendritic cell sarcoma involving the parotid gland with expression of the melanocytic marker PRAME
Follicular dendritic cell sarcoma involving the parotid gland with expression of the melanocytic marker PRAME
Follicular dendritic cell sarcoma is a rare mesenchymal neoplasm arising from follicular dendritic cells (FDC) of lymphoid...
Paraneoplastic glomerulonephritis and kidney infiltration by mantle cell lymphoma: A diagnostic challenge
Paraneoplastic glomerulonephritis and kidney infiltration by mantle cell lymphoma: A diagnostic challenge
Mantle cell lymphoma (MCL) is a rare and aggressive type of lymphoma that can affect the kidneys. The disease can lead to ...
Bridging dermatology and hematology: a case of lepromatous leprosy with bone marrow involvement and pancytopenia
Bridging dermatology and hematology: a case of lepromatous leprosy with bone marrow involvement and pancytopenia
Leprosy, caused by Mycobacterium leprae (M. leprae), primarily manifests with cutaneous and peripheral nerve invo...
Navigating diagnostic dilemmas: a rare presentation of extramedullary T-lymphoblastic leukemia/lymphoma with chronic myeloid leukemia
Navigating diagnostic dilemmas: a rare presentation of extramedullary T-lymphoblastic leukemia/lymphoma with chronic myeloid leukemia
Chronic myeloid leukemia (CML) typically presents in the chronic phase. The blast crisis phase in CML predominantly compri...
Systemic ALK-negative anaplastic large cell lymphoma with NPM1::TYK2 rearrangement
Systemic ALK-negative anaplastic large cell lymphoma with NPM1::TYK2 rearrangement
Anaplastic large cell lymphoma (ALCL) is a rare subtype of non-Hodgkin lymphoma, with most cases harboring ALK gene rearra...
Primary gastric T-cell lymphoma presenting with perforation: a case report and review of the literature
Primary gastric T-cell lymphoma presenting with perforation: a case report and review of the literature
Primary gastric T-cell lymphomas (PGTL) are exceedingly rare with an estimated incidence of 0.0091 per 100,000 person-year...
CD3/CD20/CD45 negative leukemia cutis
CD3/CD20/CD45 negative leukemia cutis
A 56-year-old male presented to the clinic with complaints of multiple skin lesions. A complete blood count (CBC) was not ...
Correction to: CD3/CD20/CD45 negative leukemia cutis
Correction to: CD3/CD20/CD45 negative leukemia cutis
A skin punch biopsy showed fragments of skin with extensive lymphoid infiltrates (Fig.1, A; x20 objective, hematoxylin and...
Secondary plasma cell leukaemia (PCL) with plasmablastic morphology
Secondary plasma cell leukaemia (PCL) with plasmablastic morphology
A 71-year-old female with relapsed IgA lambda myeloma developed progressive cytopenia. The peripheral blood film showed 5%...
Gamma-delta T-cell acute lymphoblastic lymphoma/leukemia: a report of a rare entity
Gamma-delta T-cell acute lymphoblastic lymphoma/leukemia: a report of a rare entity
Gamma delta (γδ) T-cell acute lymphoblastic leukemia/lymphoma (T-ALL) is a rare, aggressive subtype of T-lymphoi...
What is new in the 5th edition of the World Health Organization classification of mature B and T/NK cell tumors and stromal neoplasms?
What is new in the 5th edition of the World Health Organization classification of mature B and T/NK cell tumors and stromal neoplasms?
The classification of tumors is essential in the diagnosis and clinical management of patients with malignant neoplasms. T...
ALK-positive large B-cell lymphoma (ALK + LBCL) with aberrant CD3 expression
ALK-positive large B-cell lymphoma (ALK + LBCL) with aberrant CD3 expression
ALK-positive ( +) large B cell lymphoma (ALK + LBCL) is a rare distinct subtype of diffuse large B cell ...
In memorium: Dr. Zeba Singh
In memorium: Dr. Zeba Singh
We are deeply saddened by the recent passing of Dr. Zeba Singh, who left us in Novem...
Cytogenetic and pathologic characterization of MYC-rearranged B-cell lymphomas in pediatric and young adult patients
Cytogenetic and pathologic characterization of MYC-rearranged B-cell lymphomas in pediatric and young adult patients
MYC-rearranged B-cell lymphoma (BCL) in the pediatric/young adult (YA) age group differs substantially in disease composit...
Isolated Langerhans cell histiocytosis in the stomach of adults: four-case series and literature review
Isolated Langerhans cell histiocytosis in the stomach of adults: four-case series and literature review
Langerhans cell histiocytosis (LCH) of the stomach is rare. Moreover, it is usually found in pediatric patients with syste...
AI-based computational H&E staining in lymphomas
AI-based computational H&E staining in lymphomas
Ethical approval For this type of study, formal consent is not requ...
Transdifferentiation of diffuse large B-cell lymphoma to a poorly differentiated neoplasm following CAR T-cell therapy
Transdifferentiation of diffuse large B-cell lymphoma to a poorly differentiated neoplasm following CAR T-cell therapy
Chimeric antigen receptor T-cell (CAR-T) therapy is a recent advancement in precision medicine with promising results for ...
Molecular characterization of a rare case of high-grade B-cell lymphoma with MYC, BCL2, BCL6, and CCND1 rearrangements
Molecular characterization of a rare case of high-grade B-cell lymphoma with MYC, BCL2, BCL6, and CCND1 rearrangements
Quadruple-hit lymphomas are extremely rare non-Hodgkin lymphomas with a reported dismal prognosis in the few reported case...