Baird L, Yamamoto M (2020) The molecular mechanisms regulating the KEAP1-NRF2 pathway. Mol Cell Biol. https://doi.org/10.1128/MCB.00099-20
Article PubMed PubMed Central Google Scholar
Bloom DA, Jaiswal AK (2003) Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression. J Biol Chem 278:44675–44682
Article CAS PubMed Google Scholar
Chang HC, Huang DY, Wu MS, Chu CL, Tzeng SJ, Lin WW (2017) Spleen tyrosine kinase mediates the actions of EPO and GM-CSF and coordinates with TGF-beta in erythropoiesis. Biochim Biophys Acta Mol Cell Res 1864:687–696
Article CAS PubMed Google Scholar
Chen YQ, Zheng L, Aldarouish M, Zhou ZH, Pan N, Liu JQ, Chen FX, Wang LX (2018) Wnt pathway activator TWS119 enhances the proliferation and cytolytic activity of human gammadeltaT cells against colon cancer. Exp Cell Res 362:63–71
Article CAS PubMed Google Scholar
de Semir D, Bezrookove V, Nosrati M, Dar AA, Wu C, Shen J, Rieken C, Venkatasubramanian M, Miller JR 3rd, Desprez PY et al (2018) PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer. Proc Natl Acad Sci U S A 115:E5766–E5775
Article PubMed PubMed Central Google Scholar
Gao L, Gao S, Shan H, Wu Y, Zhou Q (2024) GSK-3beta inhibitor TWS119 promotes neuronal differentiation after hypoxic-ischemic brain damage in neonatal rats. NeuroReport 35:200–207
Article CAS PubMed PubMed Central Google Scholar
Giarratana MC, Kobari L, Lapillonne H, Chalmers D, Kiger L, Cynober T, Marden MC, Wajcman H, Douay L (2005) Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells. Nat Biotechnol 23:69–74
Article CAS PubMed Google Scholar
Honma Y, Okabe-Kado J, Hozumi M, Uehara Y, Mizuno S (1989) Induction of erythroid differentiation of K562 human leukemic cells by herbimycin A, an inhibitor of tyrosine kinase activity. Cancer Res 49:331–334
Ingley E (2012) Integrating novel signaling pathways involved in erythropoiesis. IUBMB Life 64:402–410
Article CAS PubMed Google Scholar
Jang SM, Zhang Y, Utani K, Fu H, Redon CE, Marks AB, Smith OK, Redmond CJ, Baris AM, Tulchinsky DA et al (2018) The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin. Nat Commun 9:2782
Article PubMed PubMed Central Google Scholar
Jang SM, Nathans JF, Fu H, Redon CE, Jenkins LM, Thakur BL, Pongor LS, Baris AM, Gross JM, O’Neill MJ et al (2020) The RepID-CRL4 ubiquitin ligase complex regulates metaphase to anaphase transition via BUB3 degradation. Nat Commun 11:24
Article CAS PubMed PubMed Central Google Scholar
Ji X, Dadon DB, Abraham BJ, Lee TI, Jaenisch R, Bradner JE, Young RA (2015) Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions. Proc Natl Acad Sci U S A 112:3841–3846
Article CAS PubMed PubMed Central Google Scholar
Jo JH, Park JU, Kim YM, Ok SM, Kim DK, Jung DH, Kim HJ, Seong HA, Cho HJ, Nah J et al (2023) RepID represses megakaryocytic differentiation by recruiting CRL4A-JARID1A at DAB2 promoter. Cell Commun Signal 21:219
Article CAS PubMed PubMed Central Google Scholar
Kang CD, Do IR, Kim KW, Ahn BK, Kim SH, Chung BS, Jhun BH, Yoo MA (1999) Role of Ras/ERK-dependent pathway in the erythroid differentiation of K562 cells. Exp Mol Med 31:76–82
Article CAS PubMed Google Scholar
Kim DK, Redon CE, Aladjem MI, Kim HK, Jang SM (2021) Molecular double clips within RepID WD40 domain control chromatin binding and CRL4-substrate assembly. Biochem Biophys Res Commun 567:208–214
Article CAS PubMed PubMed Central Google Scholar
Kolonics A, Apati A, Janossy J, Brozik A, Gati R, Schaefer A, Magocsi M (2001) Activation of Raf/ERK1/2 MAP kinase pathway is involved in GM-CSF-induced proliferation and survival but not in erythropoietin-induced differentiation of TF-1 cells. Cell Signal 13:743–754
Article CAS PubMed Google Scholar
Lee KK, Workman JL (2007) Histone acetyltransferase complexes: one size doesn’t fit all. Nat Rev Mol Cell Biol 8:284–295
Article CAS PubMed Google Scholar
Lewis JL, Marley SB, Ojo M, Gordon MY (2004) Opposing effects of PI3 kinase pathway activation on human myeloid and erythroid progenitor cell proliferation and differentiation in vitro. Exp Hematol 32:36–44
Article CAS PubMed Google Scholar
Liang R, Ghaffari S (2016) Advances in understanding the mechanisms of erythropoiesis in homeostasis and disease. Br J Haematol 174:661–673
Article CAS PubMed PubMed Central Google Scholar
Lumelsky NL, Schwartz BS (1997) Protein kinase C in erythroid and megakaryocytic differentiation: possible role in lineage determination. Biochim Biophys Acta 1358:79–92
Article CAS PubMed Google Scholar
Macari ER, Lowrey CH (2011) Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway. Blood 117:5987–5997
Article CAS PubMed PubMed Central Google Scholar
Moras M, Lefevre SD, Ostuni MA (2017) From Erythroblasts to mature red blood cells: organelle clearance in mammals. Front Physiol 8:1076
Article PubMed PubMed Central Google Scholar
Morgan MAJ, Rickels RA, Collings CK, He X, Cao K, Herz HM, Cozzolino KA, Abshiru NA, Marshall SA, Rendleman EJ et al (2017) A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation. Genes Dev 31:2003–2014
Article CAS PubMed PubMed Central Google Scholar
Morgan MAJ, Popova IK, Vaidya A, Burg JM, Marunde MR, Rendleman EJ, Dumar ZJ, Watson R, Meiners MJ, Howard SA et al (2021) A trivalent nucleosome interaction by PHIP/BRWD2 is disrupted in neurodevelopmental disorders and cancer. Genes Dev 35:1642–1656
Article CAS PubMed PubMed Central Google Scholar
Murphy ZC, Murphy K, Myers J, Getman M, Couch T, Schulz VP, Lezon-Geyda K, Palumbo C, Yan H, Mohandas N et al (2021) Regulation of RNA polymerase II activity is essential for terminal erythroid maturation. Blood 138:1740–1756
Article CAS PubMed PubMed Central Google Scholar
Myklebust JH, Blomhoff HK, Rusten LS, Stokke T, Smeland EB (2002) Activation of phosphatidylinositol 3-kinase is important for erythropoietin-induced erythropoiesis from CD34(+) hematopoietic progenitor cells. Exp Hematol 30:990–1000
Article CAS PubMed Google Scholar
Neri LM, Bortul R, Tabellini G, Borgatti P, Baldini G, Celeghini C, Capitani S, Martelli AM (2002) Erythropoietin-induced erythroid differentiation of K562 cells is accompanied by the nuclear translocation of phosphatidylinositol 3-kinase and intranuclear generation of phosphatidylinositol (3,4,5) trisphosphate. Cell Signal 14:21–29
Article CAS PubMed Google Scholar
Park JI, Choi HS, Jeong JS, Han JY, Kim IH (2001) Involvement of p38 kinase in hydroxyurea-induced differentiation of K562 cells. Cell Growth Differ 12:481–486
Popova EY, Krauss SW, Short SA, Lee G, Villalobos J, Etzell J, Koury MJ, Ney PA, Chasis JA, Grigoryev SA (2009) Chromatin condensation in terminally differentiating mouse erythroblasts does not involve special architectural proteins but depends on histone deacetylation. Chromosome Res 17:47–64
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