Adhikari N, Amin SA, Trivedi P, Jha T, Ghosh B (2018) HDAC3 is a potential validated target for cancer: an overview on the benzamide-based selective HDAC3 inhibitors through comparative SAR/QSAR/QAAR approaches. Eur J Med Chem 157:1127–1142

Article  CAS  PubMed  Google Scholar 

Chen YQ, Cipriano SC, Arenkiel JM, Miller FR (1995) Tumor suppression by p21WAF1. Cancer Res 55:4536–4539

CAS  PubMed  Google Scholar 

Chen L, Zhang X, Liu G, Chen S, Zheng M, Zhu S, Zhang S (2023) Fibroblast growth factor 3 promotes spontaneous mammary tumorigenesis in Tientsin albino 2 mice via the FGF3/FGFR1/STAT3 pathway. Front Oncol 13:1161410

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chi F, Griffiths JI, Nath A, Bild AH (2024) Paradoxical cancer cell proliferation after FGFR inhibition through decreased p21 signaling in FGFR1-amplified breast cancer cells. Breast Cancer Res 26:54

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dailey L, Ambrosetti D, Mansukhani A, Basilico C (2005) Mechanisms underlying differential responses to FGF signaling. Cytokine Growth Factor Rev 16:233–247

Article  CAS  PubMed  Google Scholar 

Douanne T, Andre-Gregoire G, Thys A, Trillet K, Gavard J, Bidere N (2019) CYLD regulates centriolar satellites proteostasis by counteracting the E3 ligase MIB1. Cell Rep 27(1657–1665):e1654

Google Scholar 

Eichner LJ, Curtis SD, Brun SN, McGuire CK, Gushterova I, Baumgart JT, Trefts E, Ross DS, Rymoff TJ, Shaw RJ (2023) HDAC3 is critical in tumor development and therapeutic resistance in Kras-mutant non-small cell lung cancer. Sci Adv 9:eadd3243

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gordziel C, Bratsch J, Moriggl R, Knosel T, Friedrich K (2013) Both STAT1 and STAT3 are favourable prognostic determinants in colorectal carcinoma. Br J Cancer 109:138–146

Article  CAS  PubMed  PubMed Central  Google Scholar 

Javidi-Sharifi N, Martinez J, English I, Joshi SK, Scopim-Ribeiro R, Viola SK, Edwards DK, Agarwal A, Lopez C, Jorgens D, Tyner JW, Druker BJ, Traer E (2019) Correction: FGF2-FGFR1 signaling regulates release of leukemia-protective exosomes from bone marrow stromal cells. Elife. https://doi.org/10.7554/eLife.47174

Article  PubMed  PubMed Central  Google Scholar 

Johnson MR, Valentine C, Basilico C, Mansukhani A (1998) FGF signaling activates STAT1 and p21 and inhibits the estrogen response and proliferation of MCF-7 cells. Oncogene 16:2647–2656

Article  CAS  PubMed  Google Scholar 

Kang K, Lee D, Hong S, Park SG, Song MR (2013) The E3 ligase Mind bomb-1 (Mib1) modulates Delta-Notch signaling to control neurogenesis and gliogenesis in the developing spinal cord. J Biol Chem 288:2580–2592

Article  CAS  PubMed  Google Scholar 

Kim HS, Lee MS (2007) STAT1 as a key modulator of cell death. Cell Signal 19:454–465

Article  CAS  PubMed  Google Scholar 

Koo BK, Lim HS, Song R, Yoon MJ, Yoon KJ, Moon JS, Kim YW, Kwon MC, Yoo KW, Kong MP et al (2005) Mind bomb 1 is essential for generating functional Notch ligands to activate Notch. Development 132:3459–3470

Article  CAS  PubMed  Google Scholar 

Koromilas AE, Sexl V (2013) The tumor suppressor function of STAT1 in breast cancer. JAKSTAT 2:e23353

PubMed  PubMed Central  Google Scholar 

Li X, Inks ES, Li X, Hou J, Chou CJ, Zhang J, Jiang Y, Zhang Y, Xu W (2014) Discovery of the first N-hydroxycinnamamide-based histone deacetylase 1/3 dual inhibitors with potent oral antitumor activity. J Med Chem 57:3324–3341

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li B, Yu L, Liu D, Yang X, Zheng Y, Gui Y, Wang H (2018) MIB1 mutations reduce Notch signaling activation and contribute to congenital heart disease. Clin Sci (Lond) 132:2483–2491

Article  CAS  PubMed  Google Scholar 

Li P, Huang T, Zou Q, Liu D, Wang Y, Tan X, Wei Y, Qiu H (2019) FGFR2 promotes expression of PD-L1 in colorectal cancer via the JAK/STAT3 signaling pathway. J Immunol 202:3065–3075

Article  CAS  PubMed  Google Scholar 

Mouron S, Manso L, Caleiras E, Rodriguez-Peralto JL, Rueda OM, Caldas C, Colomer R, Quintela-Fandino M, Bueno MJ (2021) FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer: rationale for a triple blockade of ER, CDK4/6, and FGFR1. Breast Cancer Res 23:21

Article  CAS  PubMed  PubMed Central  Google Scholar 

Park J, Kim JY, Park JW, Kang JY, Oh H, Hahm JY, Chae YC, Chakravarti D, Seo SB (2023) INHAT subunit SET/TAF-Ibeta regulates PRC1-independent H2AK119 mono-ubiquitination via E3 ligase MIB1 in colon cancer. NAR Cancer 5:zcad050

Article  PubMed  PubMed Central  Google Scholar 

Saha S, Huang SN, Yang X, Saha LK, Sun Y, Khandagale P, Jenkins LM, Pommier Y (2023) The TDRD3-USP9X complex and MIB1 regulate TOP3B homeostasis and prevent deleterious TOP3B cleavage complexes. Nat Commun 14:7524

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schneider CA, Rasband WS, Eliceiri KW (2012) NIH Image to ImageJ: 25 years of image analysis. Nat Methods 9:671–675

Article  CAS  PubMed  PubMed Central  Google Scholar 

Seo JY, Kang JS, Kim YL, Jo YW, Kim JH, Hann SH, Park J, Park I, Park H, Yoo K et al (2021) Maintenance of type 2 glycolytic myofibers with age by Mib1-Actn3 axis. Nat Commun 12:1294

Article  CAS  PubMed  PubMed Central  Google Scholar 

Servetto A, Kollipara R, Formisano L, Lin CC, Lee KM, Sudhan DR, Gonzalez-Ericsson PI, Chatterjee S, Guerrero-Zotano A, Mendiratta S et al (2021) Nuclear FGFR1 regulates gene transcription and promotes antiestrogen resistance in ER(+) breast cancer. Clin Cancer Res 27:4379–4396

Article  CAS  PubMed  PubMed Central  Google Scholar 

Terai H, Soejima K, Yasuda H, Nakayama S, Hamamoto J, Arai D, Ishioka K, Ohgino K, Ikemura S, Sato T et al (2013) Activation of the FGF2-FGFR1 autocrine pathway: a novel mechanism of acquired resistance to gefitinib in NSCLC. Mol Cancer Res 11:759–767

Article  CAS  PubMed  Google Scholar 

Touat M, Ileana E, Postel-Vinay S, Andre F, Soria JC (2015) Targeting FGFR signaling in cancer. Clin Cancer Res 21:2684–2694

Article  CAS  PubMed  Google Scholar 

Xiao L, Naganawa T, Obugunde E, Gronowicz G, Ornitz DM, Coffin JD, Hurley MM (2004) Stat1 controls postnatal bone formation by regulating fibroblast growth factor signaling in osteoblasts. J Biol Chem 279:27743–27752

Article  CAS  PubMed  Google Scholar 

Xie Y, Su N, Yang J, Tan Q, Huang S, Jin M, Ni Z, Zhang B, Zhang D, Luo F et al (2020) FGF/FGFR signaling in health and disease. Signal Transduct Target Ther 5:181

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xu G, Zhao L, Hua Q, Wang L, Liu H, Lin Z, Jin M, Wang J, Zhou P, Yang K et al (2023) CEMIP, acting as a scaffold protein for bridging GRAF1 and MIB1, promotes colorectal cancer metastasis via activating CDC42/MAPK pathway. Cell Death Dis 14:167

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yin F, Zhao R, Gorja DR, Fu X, Lu N, Huang H, Xu B, Chen H, Shim JH, Liu K et al (2022) Novel dual inhibitor for targeting PIM1 and FGFR1 kinases inhibits colorectal cancer growth in vitro and patient-derived xenografts in vivo. Acta Pharm Sin B 12:4122–4137

Article  CAS  PubMed  PubMed Central