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Role of early growth response-1 as a tumor suppressor in oral squamous cell carcinoma
Role of early growth response-1 as a tumor suppressor in oral squamous cell carcinoma
Oral squamous cell carcinoma (OSCC) exhibits pronounced local invasiveness and a propensity for lymph node metastasis. Giv...
Anti-tumor activity of butorphanol in colorectal cancer via targeting SIGMAR1
Anti-tumor activity of butorphanol in colorectal cancer via targeting SIGMAR1
Colorectal cancer (CRC) stands for a prevailing gastrointestinal neoplasm, concomitant with considerable occurrence and le...
Prognostic alternative splicing and multi-omics characteristics reveal FTCD is a potential target of hepatocellular carcinoma
Prognostic alternative splicing and multi-omics characteristics reveal FTCD is a potential target of hepatocellular carcinoma
This research aimed to identify alternative splicing (AS) variants in hepatocellular carcinoma (HCC) and assess their prog...
Type 2 diabetes and colorectal cancer: genetic causality explored via Mendelian randomization
Type 2 diabetes and colorectal cancer: genetic causality explored via Mendelian randomization
The global burden of type 2 diabetes (T2D) and colorectal cancer (CRC) continues to rise. Observational studies have sugge...
Improved lymph node detection in minimally invasive radical surgery for colorectal cancer using nanocarbon tracer
Improved lymph node detection in minimally invasive radical surgery for colorectal cancer using nanocarbon tracer
To investigate the influencing factors of lymph node detection after minimally invasive radical surgery in patients with c...
Comprehensive characterization of neddylation related genes in cutaneous melanoma identified a novel prognostic signature for treatment outcomes, immune landscape
Comprehensive characterization of neddylation related genes in cutaneous melanoma identified a novel prognostic signature for treatment outcomes, immune landscape
Neddylation, as a post-translational modification, has garnered significant attention in various tumor types recently. Few...
Novel signature of ferroptosis-related long non-coding RNA to predict lower-grade glioma overall survival
Novel signature of ferroptosis-related long non-coding RNA to predict lower-grade glioma overall survival
Ferroptosis is a novel type of programmed cell death in various tumors; however, underlying mechanisms remain unclear. We ...
Exon 1 methylation status of CDH13 is associated with decreased overall survival and distant metastasis in patients with postoperative colorectal cancer
Exon 1 methylation status of CDH13 is associated with decreased overall survival and distant metastasis in patients with postoperative colorectal cancer
Cadherin 13 (CDH13) is a member of the cadherin superfamily that exerts tumor-suppressive effects on cancers derived from ...
New direction: identification of immunoinflammatory subtypes and potential therapeutic targets for cholangiocarcinoma
New direction: identification of immunoinflammatory subtypes and potential therapeutic targets for cholangiocarcinoma
Cholangiocarcinoma (CHOL) is a rare cancer with low survival rates. Despite advances in precision medicine targeting molec...
Integrated analysis of disulfidptosis-related genes SLC7A11, SLC3A2, RPN1 and NCKAP1 across cancers
Integrated analysis of disulfidptosis-related genes SLC7A11, SLC3A2, RPN1 and NCKAP1 across cancers
Disulfidptosis, a newly identified form of regulated cell death associated with disruption of disulfide bond formation in ...
The effect and mechanism of IL-37d on neutrophil recruitment in the early stage of tumor metastasis in the lungs
The effect and mechanism of IL-37d on neutrophil recruitment in the early stage of tumor metastasis in the lungs
Chronic inflammation plays a pivotal role in cancer progression, with tumor-associated neutrophils (TANs) actively shaping...
Identification of genetic and immune mechanisms linking preeclampsia and endometrial cancer: a prognostic model for survival and treatment response
Identification of genetic and immune mechanisms linking preeclampsia and endometrial cancer: a prognostic model for survival and treatment response
Preeclampsia (PE) and endometrial cancer (EC) are two distinct conditions that share common genetic and molecular mechanis...
Recent advances on biogenesis, functions and therapeutic potential of long noncoding RNAs in T cell acute lymphoblastic leukemia
Recent advances on biogenesis, functions and therapeutic potential of long noncoding RNAs in T cell acute lymphoblastic leukemia
T-cell Acute Lymphoblastic Leukemia (T-ALL) is a highly aggressive form of ALL with at least 25% relapse rates. The high r...
The immune cells causative role in lung cancer: Mendelian randomization study
The immune cells causative role in lung cancer: Mendelian randomization study
Lung cancer (LC) is the leading cause of cancer-related deaths in China, with its incidence and mortality rates rising ann...
Evaluating KLHDC8A as a biomarker for glioma: impact on survival and proliferation through the Wnt/β-catenin pathway
Evaluating KLHDC8A as a biomarker for glioma: impact on survival and proliferation through the Wnt/β-catenin pathway
Glioma is one of the most common malignant tumors and shows a high metastasis rate and poor prognosis. KLHDC8A has been im...
Ferroptosis-related lncRNA AL136084.3 is associated with NUPR1 in bladder cancer
Ferroptosis-related lncRNA AL136084.3 is associated with NUPR1 in bladder cancer
LncRNAs are critical regulators of bladder cancer (BLCA), and ferroptosis is a newly discovered cell death responsible for...
Treatment of metastatic breast cancer by stereotactic body radiotherapy (SBRT) and stereotactic radiosurgery (SRS)
Treatment of metastatic breast cancer by stereotactic body radiotherapy (SBRT) and stereotactic radiosurgery (SRS)
The role of local ablative radiotherapy (stereotactic body radiotherapy (SBRT)/stereotactic radiosurgery (SRS)) in the man...
Investigating the biomarker value of circRNAs in the diagnosis of colorectal cancer: a systematic review
Investigating the biomarker value of circRNAs in the diagnosis of colorectal cancer: a systematic review
Circular RNAs (circRNAs) has recently been considered a class of endogenous RNAs that form a continuous closed loop with a...
Does circulating tumor DNA apply as a reliable biomarker for the diagnosis and prognosis of head and neck squamous cell carcinoma?
Does circulating tumor DNA apply as a reliable biomarker for the diagnosis and prognosis of head and neck squamous cell carcinoma?
Oral cavity cancer is the most common type of head and neck cancer. There is no definitive standard diagnosis, prognosis, ...
Deciphering the impact of aggregated autophagy-related genes TUBA1B and HSP90AA1 on colorectal cancer evolution: a single-cell sequencing study of the tumor microenvironment
Deciphering the impact of aggregated autophagy-related genes TUBA1B and HSP90AA1 on colorectal cancer evolution: a single-cell sequencing study of the tumor microenvironment
Colorectal cancer (CRC) is the third most prevalent cancer worldwide, with the tumor microenvironment (TME) playing a cruc...
A new exploration: characterization of the differentiation trajectory of prostate cancer cells
A new exploration: characterization of the differentiation trajectory of prostate cancer cells
Prostate cancer is one of the most common malignant tumors in men, and in-depth study of its gene expression patterns is c...
The impact of everolimus on hematologic parameters in patients with renal angiomyolipoma associated with tuberous sclerosis complex
The impact of everolimus on hematologic parameters in patients with renal angiomyolipoma associated with tuberous sclerosis complex
Everolimus is an effective treatment for renal angiomyolipoma associated with TSC (TSC-RAML). However, its impact on hemat...
A scoring model for the expression of genes related to programmed cell death predicts immunotherapy response and prognosis in lung adenocarcinoma
A scoring model for the expression of genes related to programmed cell death predicts immunotherapy response and prognosis in lung adenocarcinoma
Lung adenocarcinoma (LUAD) continues to be the leading cause of cancer death worldwide, driven by environmental factors li...
Pan-cancer analysis of m1A writer gene RRP8: implications for immune infiltration and prognosis in human cancers
Pan-cancer analysis of m1A writer gene RRP8: implications for immune infiltration and prognosis in human cancers
Ribosomal RNA Processing 8 (RRP8) is a gene associated with RNA modification and has been implicated in the development of...
Exploring the relationship between the interleukin family and lung adenocarcinoma through Mendelian randomization and RNA sequencing analysis
Exploring the relationship between the interleukin family and lung adenocarcinoma through Mendelian randomization and RNA sequencing analysis
Lung adenocarcinoma (LUAD) is still one of the most prevalent malignancies. Interleukin factors are closely associated wit...
LncRNA DNAH17-AS1 promotes gastric cancer proliferation and radioresistance by sponging miR-202-3p to upregulate ONECUT2
LncRNA DNAH17-AS1 promotes gastric cancer proliferation and radioresistance by sponging miR-202-3p to upregulate ONECUT2
Long noncoding RNAs (lncRNAs) are frequently dysregulated in malignancies and serve as significant regulators of tumorigen...
Identifying hub genes for chemo-radiotherapy sensitivity in cervical cancer: a bi-dataset in silico analysis
Identifying hub genes for chemo-radiotherapy sensitivity in cervical cancer: a bi-dataset in silico analysis
To identify the hub genes that associated with chemo-radiotherapy sensitivity for cervical cancer and to explore the relat...
Latrophilin-3 as a downstream effector of the androgen receptor induces bladder cancer progression
Latrophilin-3 as a downstream effector of the androgen receptor induces bladder cancer progression
Emerging evidence indicates that androgen receptor (AR) signaling plays a critical role in the pathogenesis of male-domina...
Unveiling the impact of cell death-related genes and immune dynamics on drug resistance in lung adenocarcinoma: a risk score model and functional insights
Unveiling the impact of cell death-related genes and immune dynamics on drug resistance in lung adenocarcinoma: a risk score model and functional insights
Lung adenocarcinoma (LUAD), characterized by its heterogeneity and complex pathogenesis, is the focus of this study which ...
New findings on the incidence and management of CNS adverse reactions in ALK-positive NSCLC with lorlatinib treatment
New findings on the incidence and management of CNS adverse reactions in ALK-positive NSCLC with lorlatinib treatment
To explore the presentation and control of CNS adverse reactions in patients with ALK-positive NSCLC treated with lorlatin...
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