Crick F. Central dogma of molecular biology. Nature. 1970;227(5258):561–3.

Article  CAS  PubMed  Google Scholar 

Li GW, Xie XS. Central dogma at the single-molecule level in living cells. Nature. 2011;475(7356):308–15.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jordan I, Lipkin WI. Borna disease virus. Rev Med Virol. 2001;11(1):37–57.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kruger K, et al. Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena. Cell. 1982;31(1):147–57.

Article  CAS  PubMed  Google Scholar 

Esteller M. Epigenetics in cancer. N Engl J Med. 2008;358(11):1148–59.

Article  CAS  PubMed  Google Scholar 

Parmar JJ, Padinhateeri R. Nucleosome positioning and chromatin organization. Curr Opin Struct Biol. 2020;64:111–8.

Article  CAS  PubMed  Google Scholar 

Casado-Pelaez M, Bueno-Costa A, Esteller M. Single cell cancer epigenetics. Trends Cancer. 2022;8(10):820–38.

Article  CAS  PubMed  Google Scholar 

Dawson MA, Kouzarides T. Cancer epigenetics: from mechanism to therapy. Cell. 2012;150(1):12–27.

Article  CAS  PubMed  Google Scholar 

Xiao K, et al. mRNA-based chimeric antigen receptor T cell therapy: basic principles, recent advances and future directions. Interdiscipl Med. 2024;2(1): e20230036.

Article  Google Scholar 

Reuter JA, Spacek DV, Snyder MP. High-throughput sequencing technologies. Mol Cell. 2015;58(4):586–97.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu Z, et al. Genomic characterization of peritoneal lavage cytology-positive gastric cancer. Chin J Cancer Res. 2024;36(1):66–77.

Article  PubMed  PubMed Central  Google Scholar 

Feng DC, Zhu WZ, Wang J, Li DX, Shi X, Xiong Q, You J, Han P, Qiu S, Wei Q, Yang L. The implications of single-cell RNA-seq analysis in prostate cancer: unraveling tumor heterogeneity, therapeutic implications and pathways towards personalized therapy. Mil Med Res. 2024;11(1):21. https://doi.org/10.1186/s40779-024-00526-7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Du H, et al. Single-cell RNA-seq and bulk-seq identify RAB17 as a potential regulator of angiogenesis by human dermal microvascular endothelial cells in diabetic foot ulcers. Burns & Trauma. 2023;11: tkad020.

Article  Google Scholar 

Wang S-W, et al. Current applications and future perspective of CRISPR/Cas9 gene editing in cancer. Mol Cancer. 2022;21(1):57.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dong M, et al. CRISPR/CAS9: a promising approach for the research and treatment of cardiovascular diseases. Pharmacol Res. 2022;185: 106480.

Article  CAS  PubMed  Google Scholar 

Zhao LY, et al. Mapping the epigenetic modifications of DNA and RNA. Protein Cell. 2020;11(11):792–808.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Roundtree IA, et al. Dynamic RNA modifications in gene expression regulation. Cell. 2017;169(7):1187–200.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ghidotti P, Petraroia I, Fortunato O, Pontis F. Immunomodulatory role of EV-derived non-coding RNA in lung cancer. Extracell Vesicles Circ Nucleic Acids. 2023;4(1):59-71. https://doi.org/10.20517/evcna.2022.42.

Li C, et al. N6-Methyladenosine in vascular aging and related diseases: clinical perspectives. Aging Dis. 2023. https://doi.org/10.14336/AD.2023.0924-1.

Article  PubMed  PubMed Central  Google Scholar 

Thompson MG, Sacco MT, Horner SM. How RNA modifications regulate the antiviral response. Immunol Rev. 2021;304(1):169–80.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zou D, et al. Single-cell and spatial transcriptomics reveals that PTPRG activates the m6A methyltransferase VIRMA to block mitophagy-mediated neuronal death in Alzheimer’s disease. Pharmacol Res. 2024;201: 107098.

Article  CAS  PubMed  Google Scholar 

Jin H, et al. m(1)A RNA modification in gene expression regulation. Genes. 2022;13(5):910.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yuan L, Mao L-H, Li J-Y. CAG repeat expansions increase N1-methyladenine to Alter TDP-43 phase separation: lights up therapeutic intervention for neurodegeneration. Aging Dis. 2024. https://doi.org/10.14336/AD.2024.0110.

Article  PubMed  PubMed Central  Google Scholar 

Guan Q, et al. Variant rs8400 enhances ALKBH5 expression through disrupting miR-186 binding and promotes neuroblastoma progression. Chin J Cancer Res. 2023;35(2):140–62.

Article  CAS  PubMed  PubMed Central  Google Scholar 

You K, et al. RRP8, associated with immune infiltration, is a prospective therapeutic target in hepatocellular carcinoma. J Cancer Res Clin Oncol. 2024;150(5):245.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Peifer C, et al. Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA. Nucleic Acids Res. 2013;41(2):1151–63.

Article  CAS  PubMed  Google Scholar 

Zhu C, et al. Erroneous ribosomal RNAs promote the generation of antisense ribosomal siRNA. Proc Natl Acad Sci USA. 2018;115(40):10082–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang L, et al. Nucleolar repression facilitates initiation and maintenance of senescence. Cell Cycle. 2015;14(22):3613–23.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Feng D, et al. A pan-cancer analysis of the oncogenic role of leucine zipper protein 2 in human cancer. Exp Hematol Oncol. 2022;11(1):55.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Goldman MJ, et al. Visualizing and interpreting cancer genomics data via the Xena platform. Nat Biotechnol. 2020;38(6):675–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu, J., et al., An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics. Cell, 2018. 173(2): p. 400–416 e11.

Cortese G, Scheike TH, Martinussen T. Flexible survival regression modelling. Stat Methods Med Res. 2010;19(1):5–28.

Article  PubMed