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Septic Coagulopathy: Pathophysiology, Diagnosis, and Therapeutic Strategies
Septic Coagulopathy: Pathophysiology, Diagnosis, and Therapeutic Strategies
Septic coagulopathy is a complex disorder linked with multiple organ dysfunction and increased mortality, and definitive t...
Contemporary Management of Pediatric Invasive Fungal Rhinosinusitis
Contemporary Management of Pediatric Invasive Fungal Rhinosinusitis
Pediatric invasive fungal sinusitis is a devasting disease that classically affects pediatric hematology/oncology patients...
Gastrointestinal Manifestation of MPox
Gastrointestinal Manifestation of MPox
Mpox, formerly known as monkeypox, is a zoonotic illness caused by a virus that is part of the Orthopoxvirus family. Origi...
Highly Pathogenic Avian Influenza A (H5N1) Virus Outbreak in Ecuador in 2022–2024
Highly Pathogenic Avian Influenza A (H5N1) Virus Outbreak in Ecuador in 2022–2024
Highly pathogenic avian flu viruses (HPAIVs) are considered one of the main candidates for the next pandemic due to its cu...
Defining International Critical Care Pharmacist Contributions to Sepsis and Exploring Variability
Defining International Critical Care Pharmacist Contributions to Sepsis and Exploring Variability
To define international clinical pharmacist contributions to managing sepsis in critically unwell patients and explore var...
An Update on Suppurative Tenosynovitis
An Update on Suppurative Tenosynovitis
Suppurative tenosynovitis is a serious infection mostly affecting the flexor tendons of the hand and is considered a medic...
HBV Reactivation in Patients Receiving Bruton Tyrosine Kinase Inhibitors (BTKIs): a Systematic Review and Meta-Analysis
HBV Reactivation in Patients Receiving Bruton Tyrosine Kinase Inhibitors (BTKIs): a Systematic Review and Meta-Analysis
Bruton tyrosine kinase inhibitors (BTKIs) are immunosuppressive cancer therapies approved for the treatment of various mat...
Long Story Short: Establishing Breakpoints for Antimicrobials and 2023 Updates
Long Story Short: Establishing Breakpoints for Antimicrobials and 2023 Updates
This review outlines the process of setting and revising Clinical and Laboratory Standards Institute (CLSI) breakpoints an...
Recent Advancements in the Therapeutic Development for Marburg Virus: Updates on Clinical Trials
Recent Advancements in the Therapeutic Development for Marburg Virus: Updates on Clinical Trials
We aim to provide valuable insights into the current state of therapeutic development for the deadly Marburg virus and gui...
Subtleties and differences of managing ICU patients across South Africa, Australia and UK
Subtleties and differences of managing ICU patients across South Africa, Australia and UK
Sepsis remains one of the greatest global healthcare burdens, with an estimated greater mortality rate from sepsis in Afri...
Difficult to Treat Gram-Negative Bacteria—The Indian Scenario
Difficult to Treat Gram-Negative Bacteria—The Indian Scenario
Over 50% of the infections in most ICUs in tertiary care centres in India are caused by difficult to treat (DTR) gram-nega...
Antibiotic Use at Hospital Discharge and Outpatient Antimicrobial Stewardship
Antibiotic Use at Hospital Discharge and Outpatient Antimicrobial Stewardship
Inappropriate and unnecessary antibiotic prescriptions are common in the outpatient setting and as patients transition fro...
Complex Outpatient Antimicrobial Therapy: Alternative Management Strategies and Outcomes
Complex Outpatient Antimicrobial Therapy: Alternative Management Strategies and Outcomes
Outpatient parenteral antibiotic therapy (OPAT) faces challenges requiring alternative solutions to long-term OPAT and ski...
Rebuilding for Tomorrow’s Outbreak: The State of Special Pathogen Preparedness in the USA in the Wake of COVID-19
Rebuilding for Tomorrow’s Outbreak: The State of Special Pathogen Preparedness in the USA in the Wake of COVID-19
Special pathogens require unique planning care capabilities within healthcare facilities and can pose significant public h...
Infection Prevention in Remote or Resource-Limited Settings: Deploying Technology While Preserving the Human Touch
Infection Prevention in Remote or Resource-Limited Settings: Deploying Technology While Preserving the Human Touch
Infection prevention (IP) programs face limited funding despite the COVID-19 pandemic and the continued threat of other no...
Next Steps: Studying Diabetic Foot Infections with Next-Generation Molecular Assays
Next Steps: Studying Diabetic Foot Infections with Next-Generation Molecular Assays
In 2019, the International Working Group on the Diabetic Foot voiced six concerns regarding the use of molecular microbiol...
Should We Tap That? Aspirates and Antibiotics: An Update on Septic Bursitis
Should We Tap That? Aspirates and Antibiotics: An Update on Septic Bursitis
Septic bursitis is a relatively common condition that causes substantial morbidity, but there is no universally accepted a...
The Opportunities and Challenges for Artificial Intelligence to Improve Sepsis Outcomes in the Paediatric Intensive Care Unit
The Opportunities and Challenges for Artificial Intelligence to Improve Sepsis Outcomes in the Paediatric Intensive Care Unit
To describe existing applications of artificial intelligence (AI) in sepsis management and the opportunities and challenge...
One Small Step (Down) for Antibiotics, One Giant Leap for Outpatient Therapy: The Role of Oral Antibiotics in Serious Bacterial Infections
One Small Step (Down) for Antibiotics, One Giant Leap for Outpatient Therapy: The Role of Oral Antibiotics in Serious Bacterial Infections
Stepping down to oral antibiotic therapy after a period of IV lead-in would eliminate most of the untoward effects of long...
What is New in Augmented Renal Clearance in Septic Patients?
What is New in Augmented Renal Clearance in Septic Patients?
In this narrative review encompassing relevant scientific publications regarding critically ill patients in the last 5&...
Challenges Facing PICUs in Low- and Middle-Income Countries in the Treatment of Emerging Multidrug-Resistant Organisms: a Review and Perspective from a South African PICU
Challenges Facing PICUs in Low- and Middle-Income Countries in the Treatment of Emerging Multidrug-Resistant Organisms: a Review and Perspective from a South African PICU
Antimicrobial resistance continues to increase throughout the world, with the impact on critically ill children in low- an...
Exploiting Electronic Data to Advance Knowledge and Management of Severe Infections
Exploiting Electronic Data to Advance Knowledge and Management of Severe Infections
To identify opportunities and recent advances in the use of multicentric digital data sources and networks to investigate ...
Monkeypox 2022 vs. COVID-19: a Review on a National Health Emergency with Emphasis on Cutaneous Manifestations
Monkeypox 2022 vs. COVID-19: a Review on a National Health Emergency with Emphasis on Cutaneous Manifestations
Monkeypox virus (Mpox), a rare viral zoonotic disease, has recently resurfaced as a public health emergency of internation...
Mpox in 2023: Current Epidemiology and Management
Mpox in 2023: Current Epidemiology and Management
The 2022 global mpox outbreak is a significant public health challenge. This review provides a summary of recent advanceme...
Ebola and Marburg Virus Infections in Resource-Rich Countries: Implications for Future Outbreaks
Ebola and Marburg Virus Infections in Resource-Rich Countries: Implications for Future Outbreaks
Ebolavirus and Marburgvirus are Filoviruses that cause an extremely virulent hemorrhagic fever syndrome. Most Ebolavirus (...
New Vaccines on the Immediate Horizon for Travelers: Chikungunya and Dengue Vaccines
New Vaccines on the Immediate Horizon for Travelers: Chikungunya and Dengue Vaccines
Both chikungunya and dengue virus infections are frequent in international travelers to endemic areas. More than 11 chikun...
Airport COVID-19 Testing of Travelers: An Island Destination Perspective
Airport COVID-19 Testing of Travelers: An Island Destination Perspective
To highlight recent literature on airport COVID-19 testing studies among travelers at international borders and to identif...
Prevalence and Resistance Patterns of Streptococcus pneumoniae Recovered from Children in Western Asia
Prevalence and Resistance Patterns of Streptococcus pneumoniae Recovered from Children in Western Asia
Despite the available pneumococcal conjugate vaccination (PCV), children in developing countries suffer significant morbid...
Human Papilloma Virus Related Cancers in People Living with HIV
Human Papilloma Virus Related Cancers in People Living with HIV
The burden of HPV co-infection in people living with HIV is high leading to increase incidence of HPV-related malignancies...
Japanese Encephalitis: Emergence in Australia
Japanese Encephalitis: Emergence in Australia
Recent changes in Japanese encephalitis (JE) distribution, including its emergence in mainland Australia, call for a revie...
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