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Keratinocytes – Amplifiers of Immune Responses in Systemic Lupus Erythematosus
Keratinocytes – Amplifiers of Immune Responses in Systemic Lupus Erythematosus
Epithelial cells have been acknowledged as important players in autoimmune diseases by directing and enhancing inflammator...
Unveiling the Potential of Probiotics in Osteoarthritis Management
Unveiling the Potential of Probiotics in Osteoarthritis Management
Osteoarthritis (OA), a highly prevalent degenerative joint disease, is of increasing concern due to its debilitating natur...
Immune Checkpoint Inhibitor Associated Rheumatoid Arthritis
Immune Checkpoint Inhibitor Associated Rheumatoid Arthritis
Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy over the past decade. Unfortunately, immune related ...
Recent Updates on the Pathogenesis of Inflammatory Myopathies
Recent Updates on the Pathogenesis of Inflammatory Myopathies
This review aims to provide a comprehensive and updated overview of autoimmune myopathies, with a special focus on the lat...
Treatment of Reactive Arthritis with Biological Agents
Treatment of Reactive Arthritis with Biological Agents
Reactive arthritis (ReA) is an inflammatory joint condition triggered by an infection elsewhere in the body, and this revi...
Digital Health and Self-Management in Idiopathic Inflammatory Myopathies: A Missed Opportunity?
Digital Health and Self-Management in Idiopathic Inflammatory Myopathies: A Missed Opportunity?
This paper explored the potential of digital health in idiopathic inflammatory myopathies (IIMs), with a focus on self-man...
How to Distinguish Non-Inflammatory from Inflammatory Pain in RA?
How to Distinguish Non-Inflammatory from Inflammatory Pain in RA?
Managing non-inflammatory pain in rheumatoid arthritis (RA) can be a huge burden for the rheumatologist. Pain that persist...
Classification Criteria for ANCA Associated Vasculitis – Ready for Prime Time?
Classification Criteria for ANCA Associated Vasculitis – Ready for Prime Time?
This review aims to summarize the evolution and recent developments in the classification of ANCA associated vasculitis (A...
Gaining Insight into Updated MR Imaging for Quantitative Assessment of Cartilage Injury in Knee Osteoarthritis
Gaining Insight into Updated MR Imaging for Quantitative Assessment of Cartilage Injury in Knee Osteoarthritis
Knee Osteoarthritis (KOA) entails progressive cartilage degradation, reviewed via MRI for morphology, biochemical composit...
Male Fertility in Spondyloarthritis: from Clinical Issues to Cytokines Milieu. A Narrative Review
Male Fertility in Spondyloarthritis: from Clinical Issues to Cytokines Milieu. A Narrative Review
Male fertility is an emergent issue that should be considered in clinical practice, when dealing with chronic inflammatory...
Calcium Pyrophosphate Crystal Formation and Deposition: Where Do we Stand and What Does the Future hold?
Calcium Pyrophosphate Crystal Formation and Deposition: Where Do we Stand and What Does the Future hold?
Although calcium pyrophosphate deposition (CPPD) has been known since the 1960s, our understanding of its pathogenesis rem...
JAK-STAT Signaling and Beyond in the Pathogenesis of Spondyloarthritis and Their Clinical Significance
JAK-STAT Signaling and Beyond in the Pathogenesis of Spondyloarthritis and Their Clinical Significance
Janus kinase–signal transducers and activators of transcription cell signaling proteins (JAK-STATs) play a key regul...
From Psoriasis to Psoriatic Arthritis: Ultrasound Insights Connecting Psoriasis with Subclinical Musculoskeletal Inflammation and the Path to Psoriatic Arthritis
From Psoriasis to Psoriatic Arthritis: Ultrasound Insights Connecting Psoriasis with Subclinical Musculoskeletal Inflammation and the Path to Psoriatic Arthritis
This review summarizes the literature about the transition from psoriasis to psoriatic arthritis (PsA), focusing on muscul...
Microbial Mechanisms of Rheumatoid Arthritis Pathogenesis
Microbial Mechanisms of Rheumatoid Arthritis Pathogenesis
Host-microbiome interactions have been implicated in the pathophysiology of rheumatoid arthritis (RA), but the data linkin...
Broadening the Scope of Resilience in Chronic Pain: Methods, Social Context, and Development
Broadening the Scope of Resilience in Chronic Pain: Methods, Social Context, and Development
A wellspring of new research has offered varying models of resilience in chronic pain populations; however, resilience is ...
Understanding Spondyloarthritis Pathogenesis: The Promise of Single-Cell Profiling
Understanding Spondyloarthritis Pathogenesis: The Promise of Single-Cell Profiling
Single-cell profiling, either in suspension or within the tissue context, is a rapidly evolving field. The purpose of this...
Erosive Hand Osteoarthritis: Recent Advances and Future Treatments
Erosive Hand Osteoarthritis: Recent Advances and Future Treatments
Erosive hand osteoarthritis (EHOA) is an aggressive form of hand osteoarthritis that leads to significant disability, and ...
Sequence of Events in the Pathogenesis of Axial Spondyloarthritis: A Current Review—2023 SPARTAN Meeting Proceedings
Sequence of Events in the Pathogenesis of Axial Spondyloarthritis: A Current Review—2023 SPARTAN Meeting Proceedings
Over the past two decades, significant progress has been made to untangle the etiology of inflammation and new bone format...
AA Amyloidosis: A Contemporary View
AA Amyloidosis: A Contemporary View
Amyloid A (AA) amyloidosis is an organ- or life-threatening complication of chronic inflammatory disorders. Here, we revie...
Decoding the Intricacies of Statin-Associated Muscle Symptoms
Decoding the Intricacies of Statin-Associated Muscle Symptoms
Hyperlipidemia is the major cardiovascular morbidity and mortality risk factor. Statins are the first-line treatment for h...
Antiphospholipid Patients Admitted in the Intensive Care Unit: What Must The Rheumatologist Know?
Antiphospholipid Patients Admitted in the Intensive Care Unit: What Must The Rheumatologist Know?
Antiphospholipid syndrome (APS) is a rare systemic autoimmune disorder that can escalate into a 'thrombotic storm'...
Current perspective on infections and mitigation strategies in primary systemic vasculitis
Current perspective on infections and mitigation strategies in primary systemic vasculitis
The purpose of this review is to summarize and evaluate most recent evidence on the epidemiology of infections and associa...
Thrombin Generation Assay in Antiphospholipid Antibodies Positive Subjects as a Personalized Thrombotic Risk Assessment: State of the Art and Perspectives
Thrombin Generation Assay in Antiphospholipid Antibodies Positive Subjects as a Personalized Thrombotic Risk Assessment: State of the Art and Perspectives
Thrombotic risk assessment in antiphospholipid positive (aPL +) subjects is a major challenge, and the study of in v...
How to Monitor Disease Activity of Axial Spondyloarthritis in Clinical Practice
How to Monitor Disease Activity of Axial Spondyloarthritis in Clinical Practice
Treatment guided by periodic and quantitative data assessment results in better outcomes compared to using clinical gestal...
Year in Review in Axial Spondyloarthritis Clinical Research and Guidelines: SPARTAN 2023 Annual Meeting Proceedings
Year in Review in Axial Spondyloarthritis Clinical Research and Guidelines: SPARTAN 2023 Annual Meeting Proceedings
To highlight high impact clinical publications in spondyloarthritis from May 2022 to April 2023 that were summarized and p...
Kidney Failure in Pauci-immune Crescentic Glomerulonephritis: Rationale for Immunosuppression to Improve Kidney Outcome
Kidney Failure in Pauci-immune Crescentic Glomerulonephritis: Rationale for Immunosuppression to Improve Kidney Outcome
Pauci-immune crescentic glomerulonephritis is the hallmark finding in ANCA-associated vasculitis (AAV) when the kidneys ar...
Review: The Role of Dual-Energy Computed Tomography in Detecting Monosodium Urate Deposits in Vascular Tissues
Review: The Role of Dual-Energy Computed Tomography in Detecting Monosodium Urate Deposits in Vascular Tissues
To highlight novel findings in the detection of monosodium urate deposits in vessels using dual energy computed tomography...
Calcinosis in Juvenile Dermatomyositis—Epidemiology, Pathogenesis, Clinical Features, and Treatment: A Systematic Review
Calcinosis in Juvenile Dermatomyositis—Epidemiology, Pathogenesis, Clinical Features, and Treatment: A Systematic Review
We performed a systematic review of the literature on the epidemiology, pathogenesis, clinical and laboratory characteriza...
Role of IFN-α in Rheumatoid Arthritis
Role of IFN-α in Rheumatoid Arthritis
Type 1 interferons (IFN-I) are of increasing interest across a wide range of autoimmune rheumatic diseases. Historically, ...
Cardiovascular Disease in Anti-neutrophil Cytoplasm Antibody-Associated Vasculitis
Cardiovascular Disease in Anti-neutrophil Cytoplasm Antibody-Associated Vasculitis
Anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) is a rare, multisystem, autoimmune disease character...
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