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Analysis of the causal relationship between immune cells and rheumatoid arthritis from the perspective of genetic variation: a bidirectional two-sample Mendelian randomization study
Analysis of the causal relationship between immune cells and rheumatoid arthritis from the perspective of genetic variation: a bidirectional two-sample Mendelian randomization study
Immune factors are crucial in the pathogenesis of rheumatoid arthritis (RA), and immune cells play a key role in the devel...
Treatment with tofacitinib attenuates muscle loss through myogenin activation in the collagen-induced arthritis
Treatment with tofacitinib attenuates muscle loss through myogenin activation in the collagen-induced arthritis
Sarcopenia is a muscle disease characterized by reduction of muscle strength and muscle mass. In RA, 25.9 to 43.3% of the ...
Role of type 2 ryanodine receptor stabilisation in autoimmune cell modulation
Role of type 2 ryanodine receptor stabilisation in autoimmune cell modulation
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Targeting Bruton’s tyrosine kinase (BTK) as a signaling pathway in immune-mediated diseases: from molecular mechanisms to leading treatments
Targeting Bruton’s tyrosine kinase (BTK) as a signaling pathway in immune-mediated diseases: from molecular mechanisms to leading treatments
Bruton’s tyrosine kinase (BTK), a nonreceptor tyrosine kinase, plays a remarkable role in the transmission and ampli...
Inflammatory turmoil within: an exploration of autoinflammatory disease genetic underpinnings, clinical presentations, and therapeutic approaches
Inflammatory turmoil within: an exploration of autoinflammatory disease genetic underpinnings, clinical presentations, and therapeutic approaches
Systemic autoinflammatory diseases (SAIDs) arise from dysregulated innate immune system activity, which leads to systemic ...
Challenges in implementing treat-to-target in rheumatoid arthritis: a perspective from Brazilian rheumatologists
Challenges in implementing treat-to-target in rheumatoid arthritis: a perspective from Brazilian rheumatologists
Patient management in rheumatoid arthritis (RA) has evolved to a “treat-to-target” (T2T) approach, which entai...
Determining the accuracy of the leukocyte esterase reagent strip test in the rapid diagnosis of adult septic arthritis
Determining the accuracy of the leukocyte esterase reagent strip test in the rapid diagnosis of adult septic arthritis
Septic arthritis is a dangerous disease that occurs when microorganisms enter synovial fluid. It needs fast and accurate m...
The influence of environmental factors related to Juvenile Dermatomyositis (JDM), its course and refractoriness to treatment
The influence of environmental factors related to Juvenile Dermatomyositis (JDM), its course and refractoriness to treatment
To evaluate the influence of environmental factors and prematurity relating to juvenile dermatomyositis (JDM), its course ...
Hyperuricemia and intravenous fat emulsion are risk factors for gout flares during active gastrointestinal bleeding: a case control study
Hyperuricemia and intravenous fat emulsion are risk factors for gout flares during active gastrointestinal bleeding: a case control study
It is well-established that patients with a history of gout are more susceptible to experiencing gastrointestinal bleeding...
Subclinical joint inflammation in rheumatoid arthritis: comparing thermal and ultrasound imaging at the metacarpophalangeal joint
Subclinical joint inflammation in rheumatoid arthritis: comparing thermal and ultrasound imaging at the metacarpophalangeal joint
While ultrasound and MRI are both superior to clinical examination in the detection of joint inflammation, there is presen...
Presentation of enthesitis-related arthritis and juvenile-onset spondyloarthritis: a cross-sectional study in a pediatric and adult clinic
Presentation of enthesitis-related arthritis and juvenile-onset spondyloarthritis: a cross-sectional study in a pediatric and adult clinic
Juvenile idiopathic arthritis (JIA) comprises a whole spectrum of chronic arthritis starting before 16 years of age. The s...
Effect of multidimensional physiotherapy on non-specific chronic low back pain: a randomized controlled trial
Effect of multidimensional physiotherapy on non-specific chronic low back pain: a randomized controlled trial
Many people with non-specific chronic low back pain (NSCLBP) do not recover with current conventional management. Systemat...
HLA-B27 did not protect against COVID-19 in patients with axial spondyloarthritis – data from the ReumaCov-Brasil Registry
HLA-B27 did not protect against COVID-19 in patients with axial spondyloarthritis – data from the ReumaCov-Brasil Registry
Some studies have suggested the HLA-B27 gene may protect against some infections, as well as it could play a benefit role ...
Safety and immunogenicity of influenza A(H3N2) component vaccine in juvenile systemic lupus erythematosus
Safety and immunogenicity of influenza A(H3N2) component vaccine in juvenile systemic lupus erythematosus
Seasonal influenza A (H3N2) virus is an important cause of morbidity and mortality in the last 50 years in popula...
Gamma-glutamyl transpeptidase and indirect bilirubin may participate in systemic inflammation of patients with psoriatic arthritis
Gamma-glutamyl transpeptidase and indirect bilirubin may participate in systemic inflammation of patients with psoriatic arthritis
Previous studies have suggested that systemic metabolic abnormalities are closely related to psoriatic arthritis (PsA). Ga...
COVID-19 vaccination of patients with chronic immune-mediated inflammatory disease
COVID-19 vaccination of patients with chronic immune-mediated inflammatory disease
This study aimed to analyze the safety and efficacy of COVID-19 vaccines among patients with chronic immune-mediated infla...
The use of high-sensitivity cardiac troponin I in assessing cardiac involvement and Disease prognosis in idiopathic inflammatory myopathy
The use of high-sensitivity cardiac troponin I in assessing cardiac involvement and Disease prognosis in idiopathic inflammatory myopathy
Cardiac involvement is one of the most serious complications of idiopathic inflammatory myopathy (IIM) that indicates poor...
Efficacy and safety of different Janus kinase inhibitors combined with methotrexate for the treatment of rheumatoid arthritis: a single-center randomized trial
Efficacy and safety of different Janus kinase inhibitors combined with methotrexate for the treatment of rheumatoid arthritis: a single-center randomized trial
To compare the efficacy and safety between baricitinib (BARI) and tofacitinib (TOFA) for the treatment of the rheumatoid a...
The effect of PD-1/PD-L1 signaling axis on the interaction between CD19+B cells and CD4+T cells in peripheral blood of patients with systemic lupus erythematosus
The effect of PD-1/PD-L1 signaling axis on the interaction between CD19+B cells and CD4+T cells in peripheral blood of patients with systemic lupus erythematosus
The defect of B cell self-tolerance and the continuous antigen presentation by T cells (TCs) mediated by autoreactive B ce...
The roles of immune cells in Behçet’s disease
The roles of immune cells in Behçet’s disease
Behçet’s disease (BD) is a systemic vasculitis that can affect multiple systems, including the skin, mucous mem...
Could ultrasound and muscle elastography be associated with clinical assessment, laboratory and nailfold capillaroscopy in juvenile dermatomyositis patients?
Could ultrasound and muscle elastography be associated with clinical assessment, laboratory and nailfold capillaroscopy in juvenile dermatomyositis patients?
Juvenile Dermatomyositis (JDM) is the most common idiopathic inflammatory myopathy in children. Imaging exams are useful f...
Epidemiological analysis of patients with psoriatic arthritis in follow-up at the brazilian Unified Health System
Epidemiological analysis of patients with psoriatic arthritis in follow-up at the brazilian Unified Health System
Psoriatic arthritis (PsA) is a chronic multisystem osteoarticular disease that requires specialized care. Most Brazilians ...
Correction to: Baricitinib improves pulmonary fibrosis in mice with rheumatoid arthritis-associated interstitial lung disease by inhibiting the Jak2/Stat3 signaling pathway
Correction to: Baricitinib improves pulmonary fibrosis in mice with rheumatoid arthritis-associated interstitial lung disease by inhibiting the Jak2/Stat3 signaling pathway
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Baricitinib improves pulmonary fibrosis in mice with rheumatoid arthritis-associated interstitial lung disease by inhibiting the Jak2/Stat3 signaling pathway
Baricitinib improves pulmonary fibrosis in mice with rheumatoid arthritis-associated interstitial lung disease by inhibiting the Jak2/Stat3 signaling pathway
The study explored improvements in pulmonary inflammation and fibrosis in a bovine type II collagen-induced rheumatoid art...
Extra-musculoskeletal manifestations driving the therapeutic decision-making in patients with Spondyloarthritis: a 12-month follow-up prospective cohort study
Extra-musculoskeletal manifestations driving the therapeutic decision-making in patients with Spondyloarthritis: a 12-month follow-up prospective cohort study
The extra-musculoskeletal manifestations (EMMs) such as recurrent acute anterior uveitis (rAAU), psoriasis (Ps), and infla...
TP53 and p21 (CDKN1A) polymorphisms and the risk of systemic lupus erythematosus
TP53 and p21 (CDKN1A) polymorphisms and the risk of systemic lupus erythematosus
The p53 and p21 proteins are important regulators of cell cycle and apoptosis and may contribute to autoimmune diseases, s...
Risk factors of systemic lupus erythematosus: an overview of systematic reviews and Mendelian randomization studies
Risk factors of systemic lupus erythematosus: an overview of systematic reviews and Mendelian randomization studies
The etiology of systemic lupus erythematosus is complex and incurable. A large number of systematic reviews have studied t...
Prevalence of subclinical systolic dysfunction in Takayasu’s arteritis and its association with disease activity: a cross-sectional study
Prevalence of subclinical systolic dysfunction in Takayasu’s arteritis and its association with disease activity: a cross-sectional study
Takayasu’s arteritis (TA) is a vasculitis that affects the aorta and its branches and causes stenosis, occlusion, an...
CD4 T lymphocyte subsets display heterogeneous susceptibility to apoptosis induced by serum from patients with systemic lupus erythematosus
CD4 T lymphocyte subsets display heterogeneous susceptibility to apoptosis induced by serum from patients with systemic lupus erythematosus
Serum from systemic lupus erythematosus (SLE) patients has been shown to induce T-lymphocyte (TL) apoptosis. Given that di...
Comparison of the different monosodium urate crystals in the preparation process and pro-inflammation
Comparison of the different monosodium urate crystals in the preparation process and pro-inflammation
The deposition of monosodium urate (MSU) crystals within synovial joints and tissues is the initiating factor for gout art...
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