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Gout-associated SNP at the IL1RN-IL1F10 region is associated with altered cytokine production in PBMCs of patients with gout and controls
Gout-associated SNP at the IL1RN-IL1F10 region is associated with altered cytokine production in PBMCs of patients with gout and controls
Gout is caused by the response of the innate immune system to monosodium urate (MSU) crystals. A recent gout GWAS identifi...
Genetically predicted metabolite mediates the causal relationship between immune cells and autoimmune diseases
Genetically predicted metabolite mediates the causal relationship between immune cells and autoimmune diseases
This study investigates the causal role of metabolites mediating immune cells in rheumatoid arthritis (RA) and ankylosing ...
Correction: Longitudinal assessment of reactivity and affinity profile of anti-Jo1 autoantibodies to distinct HisRS domains and a splice variant in a cohort of patients with myositis and anti-synthetase syndrome
Correction: Longitudinal assessment of reactivity and affinity profile of anti-Jo1 autoantibodies to distinct HisRS domains and a splice variant in a cohort of patients with myositis and anti-synthetase syndrome
Antonella Notarnicola, Charlotta Preger, Ingrid E. Lundberg and Cátia Fernandes-Cerqueira contributed equally to this work...
Impact of the digital health application ViViRA on spinal mobility, physical function, quality of life and pain perception in spondyloarthritides patients: a randomized controlled trial
Impact of the digital health application ViViRA on spinal mobility, physical function, quality of life and pain perception in spondyloarthritides patients: a randomized controlled trial
Spondyloarthritides (SpAs) are a group of common rheumatic diseases that often cause limited mobility and lower back pain....
Impact of systemic inflammation and disease activity on the incidence of interstitial lung disease in patients with rheumatoid arthritis – a nested case-control study within the German biologics register RABBIT
Impact of systemic inflammation and disease activity on the incidence of interstitial lung disease in patients with rheumatoid arthritis – a nested case-control study within the German biologics register RABBIT
To investigate the association between the development of incident interstitial lung disease (ILD) in patients with rheuma...
A versatile role for lung ultrasound in systemic autoimmune rheumatic diseases related pulmonary involvement: a narrative review
A versatile role for lung ultrasound in systemic autoimmune rheumatic diseases related pulmonary involvement: a narrative review
Systemic autoimmune rheumatic diseases (SARDs) related pulmonary disease is highly prevalent, with variable clinical prese...
Use of belimumab in treating patients with systemic lupus erythematosus: a single-center, real-world retrospective study
Use of belimumab in treating patients with systemic lupus erythematosus: a single-center, real-world retrospective study
To investigate the efficacy and safety of belimumab in the treatment of systemic lupus erythematosus (SLE) in a real-world...
Serum syndecan1 has the potential to reflect activity at diagnosis and predict death during follow-up in patients with ANCA-associated vasculitis
Serum syndecan1 has the potential to reflect activity at diagnosis and predict death during follow-up in patients with ANCA-associated vasculitis
This study investigated whether serum syndecan1 at diagnosis reflects activity at diagnosis and predicts poor outcomes dur...
Increased predictive value of optical spectral transmission in early rheumatoid arthritis through use of patient-adjusted cut-off scores
Increased predictive value of optical spectral transmission in early rheumatoid arthritis through use of patient-adjusted cut-off scores
The aims of this study were to suggest patient-adjusted optical spectral transmission (OST) cut-off values for the first t...
The prognosis and management of reclassified systemic lupus erythematosus associated pulmonary arterial hypertension according to 2022 ESC/ERS guidelines
The prognosis and management of reclassified systemic lupus erythematosus associated pulmonary arterial hypertension according to 2022 ESC/ERS guidelines
The 2022 European Society of Cardiology/European Respiratory Society (ESC/ERS) guideline has recently revised the hemodyna...
Epidemiological trends in psoriatic arthritis: a comprehensive population-based study
Epidemiological trends in psoriatic arthritis: a comprehensive population-based study
Psoriatic arthritis (PsA) is a chronic, potentially debilitating inflammatory arthritis often associated with psoriasis. U...
Investigating protease-mediated peptides of inflammation and tissue remodeling as biomarkers associated with flares in psoriatic arthritis
Investigating protease-mediated peptides of inflammation and tissue remodeling as biomarkers associated with flares in psoriatic arthritis
Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. PsA disease involves flares, which are a...
Microstructural changes of the white matter in systemic lupus erythematosus patients without neuropsychiatric symptoms: a multi-shell diffusion imaging study
Microstructural changes of the white matter in systemic lupus erythematosus patients without neuropsychiatric symptoms: a multi-shell diffusion imaging study
Diffusion kurtosis imaging (DKI) and neurite orientation dispersion and density imaging (NODDI) provide more comprehensive...
MiR-653-5p drives osteoarthritis pathogenesis by modulating chondrocyte senescence
MiR-653-5p drives osteoarthritis pathogenesis by modulating chondrocyte senescence
Due to the unclear pathogenesis of osteoarthritis (OA), effective treatment for this ailment is presently unavailable. Acc...
Clinical phenotypes and prognoses of microscopic polyangiitis based on kidney biopsies
Clinical phenotypes and prognoses of microscopic polyangiitis based on kidney biopsies
To classify the different clinical phenotypes and compare the distinct prognoses of microscopic polyangiitis (MPA). A retr...
Pathological progress and remission strategies of osteoarthritic lesions caused by long-term joint immobilization
Pathological progress and remission strategies of osteoarthritic lesions caused by long-term joint immobilization
While joint immobilization is a useful repair method for intra-articular ligament injury and periarticular fracture, prolo...
Efficient delivery of the lncRNA LEF1-AS1 through the antibody LAIR-1 (CD305)-modified Zn-Adenine targets articular inflammation to enhance the treatment of rheumatoid arthritis
Efficient delivery of the lncRNA LEF1-AS1 through the antibody LAIR-1 (CD305)-modified Zn-Adenine targets articular inflammation to enhance the treatment of rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by synovial hyperplasia. Maintaining ...
Prokineticin 2 is a catabolic regulator of osteoarthritic cartilage destruction in mouse
Prokineticin 2 is a catabolic regulator of osteoarthritic cartilage destruction in mouse
Our preliminary study indicates that the multi-functional protein, prokineticin 2 (Prok2), is upregulated in osteoarthriti...
Fructose-bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3)
Fructose-bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3)
To identify the role of gluconeogenesis in chondrocytes in osteoarthritis (OA). Cartilage samples were collected from OA p...
Machine learning and molecular subtype analyses provide insights into PANoptosis-associated genes in rheumatoid arthritis
Machine learning and molecular subtype analyses provide insights into PANoptosis-associated genes in rheumatoid arthritis
PANoptosis represents a newly identified form of programmed cell death that plays a significant role in the autoimmune dis...
Age-dependent genetic regulation of osteoarthritis: independent effects of immune system genes
Age-dependent genetic regulation of osteoarthritis: independent effects of immune system genes
Osteoarthritis (OA) is a joint disease with a heritable component. Genetic loci identified via genome-wide association stu...
Alterations in lipidome profiles distinguish early-onset hyperuricemia, gout, and the effect of urate-lowering treatment
Alterations in lipidome profiles distinguish early-onset hyperuricemia, gout, and the effect of urate-lowering treatment
Currently, it is not possible to predict whether patients with hyperuricemia (HUA) will develop gout and how this progress...
Resatorvid alleviates experimental inflammatory TMJOA by restraining chondrocyte pyroptosis and synovial inflammation
Resatorvid alleviates experimental inflammatory TMJOA by restraining chondrocyte pyroptosis and synovial inflammation
Innate immunity plays a significant role in the pathogenesis of temporomandibular joint osteoarthritis (TMJOA), which is c...
The relation between synovitis of individual finger joints and grip force over the first 5 years in early rheumatoid arthritis — a cohort study
The relation between synovitis of individual finger joints and grip force over the first 5 years in early rheumatoid arthritis — a cohort study
The objective of this study was to investigate the relation between swelling and tenderness of individual finger joints an...
Characterization of human placenta-derived exosome (pExo) as a potential osteoarthritis disease modifying therapeutic
Characterization of human placenta-derived exosome (pExo) as a potential osteoarthritis disease modifying therapeutic
Human placenta-derived exosomes (pExo) were generated, characterized, and evaluated as a therapeutic candidate for the tre...
Long-term follow-up of children with chronic non-bacterial osteomyelitis—assessment of disease activity, risk factors, and outcome
Long-term follow-up of children with chronic non-bacterial osteomyelitis—assessment of disease activity, risk factors, and outcome
Chronic non-bacterial osteomyelitis (CNO) is an autoinflammatory bone-disease of unknown origin. The National Pediatric Rh...
Differential expression pattern of Bcl-2 family members in B and T cells in systemic lupus erythematosus and rheumatoid arthritis
Differential expression pattern of Bcl-2 family members in B and T cells in systemic lupus erythematosus and rheumatoid arthritis
This study aimed to evaluate the expression level of anti-apoptotic Bcl-2 family proteins in B and T cells in patients wit...
Assessing clusters of comorbidities in rheumatoid arthritis: a machine learning approach
Assessing clusters of comorbidities in rheumatoid arthritis: a machine learning approach
Comorbid conditions are very common in rheumatoid arthritis (RA) and several prior studies have clustered them using machi...
Assessment of axial spondyloarthritis activity using a magnetic resonance imaging-based multi-region-of-interest fusion model
Assessment of axial spondyloarthritis activity using a magnetic resonance imaging-based multi-region-of-interest fusion model
Identifying axial spondyloarthritis (axSpA) activity early and accurately is essential for treating physicians to adjust t...
Impact of IL6R genetic variants on treatment efficacy and toxicity response to sarilumab in rheumatoid arthritis
Impact of IL6R genetic variants on treatment efficacy and toxicity response to sarilumab in rheumatoid arthritis
Sarilumab, an IL-6 receptor antagonist, is a first-line biologic disease-modifying anti-rheumatic drug for rheumatoid arth...
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