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Modulation of HIF1α/CXCR4 by CDDP, acetazolamide, and salidroside in early lung injury caused by acute high-altitude hypoxia
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Dihydromyricetin exerts dual anti-acne actions by suppressing propionibacterium acnes proliferation and host inflammatory responses via TLR2/NF-κB/MAPK pathway inhibition
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Modulating monoaminergic systems: A study on 3,5-dimethyl-1-phenyl-4-(phenylselenyl)-1H-pyrazole in lipopolysaccharide-induced depressive-like symptoms in mice
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Forskolin alleviates cholestatic liver disease by inhibiting the Hippo/YAP-mediated ductular reaction and fibrosis progression
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Lactobacillus reuteri attenuates methotrexate-induced liver injury via modulation of oxidative stress and inflammation through HO-1/GPX4 and NF-κB/NLRP3 pathways
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Design, synthesis, and preclinical evaluation of novel 1-benzylpiperidine derivatives as multitarget agents against Alzheimer's disease
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Phospholysine phosphohistidine inorganic pyrophosphate phosphatase suppresses glycolysis and proliferation of pulmonary artery smooth muscle cells in hypoxic pulmonary hypertension via inhibition of lactate dehydrogenase A
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Varenicline as a cardioprotective agent against doxorubicin-induced toxicity: A study on apoptotic, TLR4/NF-κB, and inflammasome/caspase-1/IL-1β pathway modulation in a rat model
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Remimazolam alleviates intracerebral hemorrhage outcomes by suppressing neuronal ferroptosis
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Preclinical study on cynaroside as a selective granzyme B inhibitor in the treatment of atopic dermatitis
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Quercetin attenuates busulfan-induced testicular and epididymal toxicity via modulation of oxidative stress, inflammatory cytokines, and apoptotic markers in rats
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HEC95468, a novel soluble guanylate cyclase stimulator, shows protection in the Dahl model of cardiorenal disorder
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8-epi-Helenalin suppresses tumorigenesis and metastasis by modulating the STAT3/FAK signaling axis
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Research progress of lung organoids in infectious respiratory diseases
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Salicylic acid inhibits Mas-related G protein-coupled receptor X2-mediated mast cell 2 activation and mitigates cutaneous pseudo-allergic reactions
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Sirtuin 6-driven ASC deacetylation confers hepatoprotection: A promising approach to inflammasome inhibition in experimental NASH
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The anticonvulsant activity of trace amine-associated receptor 1 (TAAR1) agonists involves GABAB receptors in mice
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Mapping the evolving landscape of lecanemab research in Alzheimer's Disease: A bibliometric analysis
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Exploring Prima-1MET as a single agent or in combination with tamoxifen in breast cancer cells in vitro
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Protective effects of acemannan-enriched Aloe polysaccharide J2 against UVA-induced autophagic cell death in retinal pigment epithelial cells
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Sodium-glucose cotransporter 2 inhibitor empagliflozin enhances autophagy and reverses remodeling in hearts with large, old myocardial infarctions
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Disulfiram alleviates immune-mediated liver injury by inhibiting pyroptosis in hepatocytes through the NF-κB pathway
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Hydrogen-rich water ameliorates imiquimod-induced psoriasis-like skin lesions and regulates macrophage polarization in dyslipidemic ApoE-deficient mice
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The diabetes medication Canagliflozin attenuates alcoholic liver disease by reducing hepatic lipid accumulation via SIRT1-AMPK-mTORC1 signaling pathway
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Protective effects of atorvastatin on testicular dysfunction and reduced sperm quality induced by high-fat diet in mice: The inhibitory mechanism of oxidative stress
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Agmatine mitigates hyperexcitability of ventral tegmental area dopaminergic neurons in prenatally stressed male offspring
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Current applications, future Perspectives and challenges of Organoid technology in oral cancer research
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4-Hydroxyestrogen metabolites strongly prevent chemically-induced ferroptotic hepatocyte injury in vitro and in vivo
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A novel neural network-based nearest neighbor approach for drug function prediction from chemical structures
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Safety, tolerability and pharmacokinetic profile of the low-impact ampakine CX717 in young healthy male subjects and elderly healthy male and female subjects
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