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The thiodiketopiperazine derivatives shovelmycin A–B and ansamycin derivative divergolide X from the cold-seep-derived Streptomyces olivaceus HDN22-001
The thiodiketopiperazine derivatives shovelmycin A–B and ansamycin derivative divergolide X from the cold-seep-derived Streptomyces olivaceus HDN22-001
Three new compounds including two thiodiketopiperazine derivatives shovelmycins A–B (1–2), and one ansamycin d...
Correction: New potentiators of amphotericin B activity, shodoamides A to C produced by Pseudophialophora sp. BF-0158
Correction to: The Journal of AntibioticsThe authors of the above article no...
Remembering Professor Kazuo Umezawa (6 December 1946– 12 January 2024)
Remembering Professor Kazuo Umezawa (6 December 1946– 12 January 2024)
Professor Kazuo UmezawaProfessor Kazuo Umezawa passed away on January 12, 20...
Bioactive hydrogenated azaphilones from acid-tolerant fungus Penicillium purpureum OUCMDZ-019
Bioactive hydrogenated azaphilones from acid-tolerant fungus Penicillium purpureum OUCMDZ-019
Two new hydrogenated azaphilones (1 and 2), together with the known azaphilone (3) were isolated from the red soil-derived...
Sporogen-AO1 inhibits eukaryotic translation elongation
Sporogen-AO1 inhibits eukaryotic translation elongation
Sporogen-AO1, a sporulation-promoting substance of Aspergillus oryzae was found to be a nonspecific translation inhibitor ...
Terramide A: a novel ironophore targeting Acinetobacter baumannii with mechanistic insights into bacterial iron deprivation
Terramide A: a novel ironophore targeting Acinetobacter baumannii with mechanistic insights into bacterial iron deprivation
Acetobacter baumannii poses escalating clinical challenges due to its exceptional adaptability, demanding innovative antim...
Biosynthesis of antibiotics with sulfonamide and azaindane moieties
Biosynthesis of antibiotics with sulfonamide and azaindane moieties
As research into the biosynthesis of natural products has matured, the biosynthetic pathways of common skeletons have been...
Drimane sesquiterpene esters produced by Aspergillus insuetus BF-1613 as inhibitors of sterol O-acyltransferase
Drimane sesquiterpene esters produced by Aspergillus insuetus BF-1613 as inhibitors of sterol O-acyltransferase
A new drimane sesquiterpene ester, designated insuetusolate (1), and four reported ones (2–5) were isolated from a c...
Correction: Synthesis and antibacterial action of 3’,6’-disubstituted spectinomycins
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Exploration of vanoxerine analogues as antibacterial agents
Exploration of vanoxerine analogues as antibacterial agents
Mycobacterium tuberculosis is a bacterial pathogen, responsible for approximately 1.3 million deaths in 2022 through tuber...
Resistance to linezolid in Staphylococcus aureus by mutation, modification, and acquisition of genes
Resistance to linezolid in Staphylococcus aureus by mutation, modification, and acquisition of genes
Linezolid binds to the 50S subunit of the bacterial ribosome, inhibiting bacterial protein synthesis by preventing the for...
Streptomyces yaizuensis sp. nov., a berninamycin C-producing actinomycete isolated from sponge
Streptomyces yaizuensis sp. nov., a berninamycin C-producing actinomycete isolated from sponge
While screening for antibiotics in a marine sample, we discovered a berninamycin C-producing actinomycete, designated YSPA...
Sinulariapeptide F, a new peptide from culture broth of marine-derived fungus Simplicillium sp. SCSIO 41222
Sinulariapeptide F, a new peptide from culture broth of marine-derived fungus Simplicillium sp. SCSIO 41222
One new compound named sinulariapeptide F (1) together with one known butyrolactone (2) and seven known peptides (3–...
Thiazoplanomicin, a new thiazolyl peptide antibiotic from the leaf-litter actinomycete Actinoplanes sp. MM794L-181F6
Thiazoplanomicin, a new thiazolyl peptide antibiotic from the leaf-litter actinomycete Actinoplanes sp. MM794L-181F6
A new bioactive substance was identified from a leaf-litter actinomycete strain by screening for antibacterial activity ag...
Antimicrobial activity of α/β hybrid peptides incorporating tBu-β3,3Ac6c against methicillin-resistant Staphylococcus aureus
Antimicrobial activity of α/β hybrid peptides incorporating tBu-β3,3Ac6c against methicillin-resistant Staphylococcus aureus
The incorporation of β-amino acids into peptides is a promising approach to develop proteolytically stable therapeuti...
Correlation between the spread of IMP-producing bacteria and the promoter strength of blaIMP genes
Correlation between the spread of IMP-producing bacteria and the promoter strength of blaIMP genes
The first report of transmissible carbapenem resistance encoded by blaIMP-1 was discovered in Pseudomonas aeruginosa GN172...
Structure of prolylrapamycin: confirmation through a revised and detailed NMR assignment study
Structure of prolylrapamycin: confirmation through a revised and detailed NMR assignment study
A complete and detailed characterization of Rapamycin (1) and Prolylrapamycin (2) has been conducted by homo- and hetero-n...
Uncovering the potentiality of quinazoline derivatives against Pseudomonas aeruginosa with antimicrobial synergy and SAR analysis
Uncovering the potentiality of quinazoline derivatives against Pseudomonas aeruginosa with antimicrobial synergy and SAR analysis
Antimicrobial resistance has emerged as a covert global health crisis, posing a significant threat to humanity. If left un...
Okichromanone, a new antiviral chromanone from a marine-derived Microbispora
Okichromanone, a new antiviral chromanone from a marine-derived Microbispora
Okichromanone (1), a new chromanone, was isolated from the culture extract of a sponge-derived actinomycete Microbispora, ...
Three new phthalide derivatives from culture broth of Dentipellis fragilis and their cytotoxic activities
Three new phthalide derivatives from culture broth of Dentipellis fragilis and their cytotoxic activities
Three new phthalide derivatives (1‒3) together with two known compounds, erinaceolactone B (4) and hericerin III (5)...
Actinomycetospora termitidis sp. nov., an insect-derived actinomycete isolated from termite (Odontotermes formosanus)
Actinomycetospora termitidis sp. nov., an insect-derived actinomycete isolated from termite (Odontotermes formosanus)
Strain Odt1-22T, an insect-derived actinomycete was isolated from a termite (Odontotermes formosanus) that was collected f...
Tumescenamide C, a cyclic lipodepsipeptide from Streptomyces sp. KUSC_F05, exerts antimicrobial activity against the scab-forming actinomycete Streptomyces scabiei
Tumescenamide C, a cyclic lipodepsipeptide from Streptomyces sp. KUSC_F05, exerts antimicrobial activity against the scab-forming actinomycete Streptomyces scabiei
The antimicrobial activity of tumescenamide C against the scab-forming S. scabiei NBRC13768 was confirmed with a potent IC...
New polycyclic tetramate macrolactams with antimycobacterial activity produced by marine-derived Streptomyces sp. KKMA-0239
New polycyclic tetramate macrolactams with antimycobacterial activity produced by marine-derived Streptomyces sp. KKMA-0239
During our screening for anti-mycobacterial agents against Mycobacterium avium complex (MAC), two new polycyclic tetramate...
Anti-microbial efficacy of l-glutaminase (EC 3.5.1.2) against multidrug-resistant Pseudomonas aeruginosa infection
Anti-microbial efficacy of l-glutaminase (EC 3.5.1.2) against multidrug-resistant Pseudomonas aeruginosa infection
The aims of this study were isolation-purification and characterization of l-glutaminase from L. gasseri BRLHM clinical is...
Antimicrobial resistance rates of urogenital Mycoplasma hominis and Ureaplasma species before and during the COVID-19 pandemic: results from a Greek survey, 2014 to 2022
Antimicrobial resistance rates of urogenital Mycoplasma hominis and Ureaplasma species before and during the COVID-19 pandemic: results from a Greek survey, 2014 to 2022
The prevalence of antibiotic-resistant urogenital mycoplasmas and ureaplasmas has been gradually increasing over the years...
Remembering Dr. Shinichi Kondo (15 June 1928–8 October 2022)
Remembering Dr. Shinichi Kondo (15 June 1928–8 October 2022)
Dr. Shinichi Kondo, an Emeritus Member of the Journal of Antibiotics, died on October 8, 2022 at his ...
Chromatin-modifying protein 4C (CHMP4C) affects breast cancer cell growth and doxorubicin resistance as a potential breast cancer therapeutic target
Chromatin-modifying protein 4C (CHMP4C) affects breast cancer cell growth and doxorubicin resistance as a potential breast cancer therapeutic target
Breast cancer (BCa) is one of the common malignancies among women. Doxorubicin (Dox), a type of anthracycline anti-tumor d...
Retraction Note: Molecular docking simulation, drug-likeness assessment, and pharmacokinetic study of some cephalosporin analogues against a penicillin-binding protein of Salmonella typhimurium
Retraction to: The Journal of AntibioticsThe Editor-in-chief has retracted this article because after the publication of t...
Two new adenopeptins B and C inhibit sphere formation of pancreatic cancer cells
Two new adenopeptins B and C inhibit sphere formation of pancreatic cancer cells
Cancer remains one of the leading causes of death worldwide, particularly pancreatic cancer being lethal because of its ag...
Evaluation of A-ring hydroxymethylene-amino- triterpenoids as inhibitors of SARS-CoV-2 spike pseudovirus and influenza H1N1
Evaluation of A-ring hydroxymethylene-amino- triterpenoids as inhibitors of SARS-CoV-2 spike pseudovirus and influenza H1N1
A set of triterpene A-ring hydroxymethylene-amino-derivatives was synthesized and their antiviral activity was studied. Th...
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