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Comparative evaluation of different oral iron salts in the management of iron deficiency anemia
Comparative evaluation of different oral iron salts in the management of iron deficiency anemia
Anemia affects one-fourth of the world's population and is caused mostly by iron deficiency. Iron supplementation is t...
Toxicological effect of acetaminophen, metamizole, and nimesulide cocktail on early development of zebrafish
Toxicological effect of acetaminophen, metamizole, and nimesulide cocktail on early development of zebrafish
Several countries’ most incorrectly discarded medicines are acetaminophen (ACM), metamizole (MTZ), and nimesulide (N...
One-pot synthesis of polysaccharide/gelatin amorphous hydrogels impregnated with a bioflavonoid derived from Elaeis guineensis leaf: wound healing and drug release properties
One-pot synthesis of polysaccharide/gelatin amorphous hydrogels impregnated with a bioflavonoid derived from Elaeis guineensis leaf: wound healing and drug release properties
Amorphous hydrogel is a strategic wound healing dressings that comprised of water, polymers and excipients with no shape. ...
A synthetic curcumin-like diarylpentanoid analog inhibits rhinovirus infection in H1 hela cells via multiple antiviral mechanisms
A synthetic curcumin-like diarylpentanoid analog inhibits rhinovirus infection in H1 hela cells via multiple antiviral mechanisms
Rhinovirus (RV) infection is a major cause of common colds and asthma exacerbations, with no antiviral drug available. Cur...
Targeting resistant breast cancer stem cells in a three-dimensional culture model with oleuropein encapsulated in methacrylated alginate microparticles
Targeting resistant breast cancer stem cells in a three-dimensional culture model with oleuropein encapsulated in methacrylated alginate microparticles
Cancer stem cells (CSCs) are a subpopulation of cancer cells that are believed to be responsible for tumor initiation, pro...
Dry powder inhaler design and particle technology in enhancing Pulmonary drug deposition: challenges and future strategies
Dry powder inhaler design and particle technology in enhancing Pulmonary drug deposition: challenges and future strategies
The efficient delivery of drugs from dry powder inhaler (DPI) formulations is associated with the complex interaction betw...
Structure-activity relationship of pharmacophores and toxicophores: the need for clinical strategy
Structure-activity relationship of pharmacophores and toxicophores: the need for clinical strategy
Sometimes clinical efficacy and potential risk of therapeutic and toxic agents are difficult to predict over a long period...
Glatiramer acetate in situ forming gel, a new approach for multiple sclerosis treatment
Glatiramer acetate in situ forming gel, a new approach for multiple sclerosis treatment
Glatiramer acetate (GA), a commonly used treatment for multiple sclerosis (MS), requires long-term frequent injections to ...
Ameliorative effect of Melatonin on 5-Fluorouracil-induced reproductive toxicity in male rats
Ameliorative effect of Melatonin on 5-Fluorouracil-induced reproductive toxicity in male rats
5-Fluorouracil (5-FU) is an antimetabolite chemotherapeutic agent that can cause oxidative stress and complications in nor...
Repurposing metformin as a potential anticancer agent using in silico technique
Repurposing metformin as a potential anticancer agent using in silico technique
The focus on repurposing readily available, well-known drugs for new, creative uses has grown recently. One such medicatio...
Structure based exploration of mitochondrial alpha carbonic anhydrase inhibitors as potential leads for anti-obesity drug development
Structure based exploration of mitochondrial alpha carbonic anhydrase inhibitors as potential leads for anti-obesity drug development
Obesity has emerged as a major health challenge globally in the last two decades. Dysregulated fatty acid metabolism and d...
A review of the ethnomedicinal, phytochemical, and pharmacological properties of the Ferulago genus based on Structure–Activity Relationship (SAR) of coumarins
A review of the ethnomedicinal, phytochemical, and pharmacological properties of the Ferulago genus based on Structure–Activity Relationship (SAR) of coumarins
The Ferluago W.D.J. Koch genus includes 48 accepted perennial herbs that are distributed in the Mediterranean region, Sout...
Prediction of naloxone dose in opioids toxicity based on machine learning techniques (artificial intelligence)
Prediction of naloxone dose in opioids toxicity based on machine learning techniques (artificial intelligence)
Treatment management for opioid poisoning is critical and, at the same time, requires specialized knowledge and skills. Th...
Dispersive micro-solid phase extraction based on two MOFs as highly effective adsorbents for analysis of nilotinib in plasma and wastewater
Dispersive micro-solid phase extraction based on two MOFs as highly effective adsorbents for analysis of nilotinib in plasma and wastewater
Nilotinib (NIL) is a prescription medication employed in the treatment of specific types of leukemia, namely chronic myelo...
Investigation of the relationship between inflammation and microbiota in the intestinal tissue of female and male rats fed with fructose: Modulatory role of metformin
Investigation of the relationship between inflammation and microbiota in the intestinal tissue of female and male rats fed with fructose: Modulatory role of metformin
It has been reported that High-Fructose (HF) consumption, considered one of the etiological factors of Metabolic Syndrome ...
Public interest in drug-related problems reflected in information search trends: an infodemiological study
Public interest in drug-related problems reflected in information search trends: an infodemiological study
The analysis of how people search and “navigate” the internet to obtain health-related information and how the...
Population Pharmacokinetics of Loxoprofen and its alcoholic metabolites in healthy Korean men
Population Pharmacokinetics of Loxoprofen and its alcoholic metabolites in healthy Korean men
Loxoprofen has been actively used clinically to relieve musculoskeletal pain and inflammatory symptoms. However, there are...
Evaluating the effect of sodium alginate and sodium carboxymethylcellulose on pulmonary delivery of levofloxacin spray-dried microparticles
Evaluating the effect of sodium alginate and sodium carboxymethylcellulose on pulmonary delivery of levofloxacin spray-dried microparticles
Patients with cystic fibrosis commonly suffer from lung infections caused by Pseudomonas aeruginosa. Recently, the Levoflo...
Pharmacogenetic DPYD allele variant frequencies: A comprehensive analysis across an ancestrally diverse Iranian population
Pharmacogenetic DPYD allele variant frequencies: A comprehensive analysis across an ancestrally diverse Iranian population
Cancer treatment has improved over the past decades, but many cancer patients still experience adverse drug reactions (ADR...
Evaluation of time-to-onset and outcome of cardiac adverse events related to pembrolizumab using post-marketing surveillance in Japanese patients
Evaluation of time-to-onset and outcome of cardiac adverse events related to pembrolizumab using post-marketing surveillance in Japanese patients
Pembrolizumab has been widely used in patients since its release, but information on cardiac Adverse Events (AEs) related ...
Imiquimod as a new treatment in refractory idiopathic granulomatous mastitis: report of two cases
Imiquimod as a new treatment in refractory idiopathic granulomatous mastitis: report of two cases
Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory lesion of the breast that mimics breast cancer or i...
Cost minimization analysis of subcutaneous trastuzumab versus intravenous biosimilar trastuzumab: policy recommendations for breast cancer treatment in Malaysia
Cost minimization analysis of subcutaneous trastuzumab versus intravenous biosimilar trastuzumab: policy recommendations for breast cancer treatment in Malaysia
Current clinical practice recommends switching innovator intravenous trastuzumab (IV-TZMi) to subcutaneous trastuzumab (SC...
Oral regimen for high dose methotrexate urine alkalinization: a systematic review and meta-analysis
Oral regimen for high dose methotrexate urine alkalinization: a systematic review and meta-analysis
Urine alkalinization prevents nephrotoxicity in patients receiving high-dose methotrexate (HDMTX). While the standard appr...
Dexmedetomidine alleviates Hypoxia/reoxygenation-induced mitochondrial dysfunction in cardiomyocytes via activation of Sirt3/Prdx3 pathway
Dexmedetomidine alleviates Hypoxia/reoxygenation-induced mitochondrial dysfunction in cardiomyocytes via activation of Sirt3/Prdx3 pathway
Myocardial ischemia/reperfusion injury (MIRI) seriously threatens the health of people. The mitochondrial dysfunction in c...
New amide and diterpene alkaloids with anticholinesterase activity from Delphinium cyphoplectrum roots
New amide and diterpene alkaloids with anticholinesterase activity from Delphinium cyphoplectrum roots
The cholinergic hypothesis posits a robust correlation between the onset of Alzheimer’s disease and a pronounced def...
Developing an AI-based prediction model for anaphylactic shock from injection drugs using Japanese real-world data and chemical structure-based analysis
Developing an AI-based prediction model for anaphylactic shock from injection drugs using Japanese real-world data and chemical structure-based analysis
This study aims to develop an AI-based prediction model for injection drugs that cause anaphylactic shock using Japanese R...
Activity of zinc oxide and zinc borate nanoparticles against resistant bacteria in an experimental lung cancer model
Activity of zinc oxide and zinc borate nanoparticles against resistant bacteria in an experimental lung cancer model
Recent research indicates a prevalence of typical lung infections, such as pneumonia, in lung cancer patients. Klebsiella ...
Deciphering the similarities and disparities of molecular mechanisms behind respiratory epithelium response to HCoV-229E and SARS-CoV-2 and drug repurposing, a systems biology approach
Deciphering the similarities and disparities of molecular mechanisms behind respiratory epithelium response to HCoV-229E and SARS-CoV-2 and drug repurposing, a systems biology approach
Identifying the molecular mechanisms behind SARS-CoV-2 disparities and similarities will help find new treatments. The pre...
Evaluation of 1,10-phenanthroline-based hydroxamate derivative as dual histone deacetylases/ribonucleotide reductase inhibitor with antitumor activities
Evaluation of 1,10-phenanthroline-based hydroxamate derivative as dual histone deacetylases/ribonucleotide reductase inhibitor with antitumor activities
Aberrant expression of histone deacetylases (HDACs) and ribonucleotide reductase (RR) enzymes are commonly observed in var...
The association between anti-diabetic agents and osteoporosis, sarcopenia, and osteosarcopenia among Iranian older adults; Bushehr Elderly Health (BEH) program
The association between anti-diabetic agents and osteoporosis, sarcopenia, and osteosarcopenia among Iranian older adults; Bushehr Elderly Health (BEH) program
Various risk factors are mentioned for osteoporosis, sarcopenia, and osteosarcopenia. Our aim is to assess the impacts of ...
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