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Intradermal and transdermal absorption of beta-naphthylamine and N-Phenyl-beta-naphthylamine in a viable human skin model
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Ex vivo skin diffusion and decontamination studies of titanium dioxide nanoparticles
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Can TK-TD modelling bridge the gap between in vitro and in vivo mammalian toxicity data?
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Reliability and relevance of the ES®-RHE model for in vitro skin irritation test application
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Applying cell painting in non-tumorigenic breast cells to understand impacts of common chemical exposures
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The role of efflux transporters in cytotoxicity and intracellular concentration of chlorpyrifos and chlorpyrifos oxon in human cell lines
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Evaluation of a New In Chemico Skin Corrosion Test
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Cigarette smoke extract decreases human bone marrow mesenchymal stromal cell adipogenic differentiation
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Effect of curcumin on the embryotoxic effect of ethanol in a zebrafish model
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Go with the flow: An in vitro model of a mature endothelium for the study of the bioresponse of IV injectable nanomedicines
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A high throughput screening assay for human Thyroperoxidase inhibitors
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Assessment of ursolic acid effect on in vitro model of cardiac fibrosis
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Corrigendum to “Novel Diphenyl urea derivative serves as an inhibitor on human lung cancer cell migration by disrupting EMT via Wnt/β-catenin and PI3K/Akt signaling” [Toxicology in Vitro 69 (2020) 105000]
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NDMA enhances claudin-1 and -6 expression viaCYP2E1/ROS in AGS cells
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Dihydrotanshinone I induces necroptosis and cell cycle arrest in gastric cancer through the PTPN11/p38 pathway
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Curcumin-loaded emulsome nanoparticles induces apoptosis through p53 signaling pathway in pancreatic cancer cell line PANC-1
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Heat shock protein HSPA8 impedes hemin-induced cellular-toxicity in liver
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Food grade titanium dioxide induced endoplasmic reticulum stress in colon cells: Comparison between normal and colorectal carcinoma cells
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Anticancer activity of EMD37 against human head and neck cancer: Impact on apoptotic and inflammatory machineries
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Integration of MUTZ-Langerhans cells into a 3D full-thickness skin equivalent and influences of serum reduction and undefined medium supplements on differentiation
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Gill epithelial cell line ASG-10 from Atlantic salmon as a new research tool for solving water quality challenges in aquaculture
Gill epithelial cell line ASG-10 from Atlantic salmon as a new research tool for solving water quality challenges in aquaculture
Here we evaluated the gill epithelial cell line ASG-10 from Atlantic salmon, as an in vitro model for research on known wa...
Fragrances as a trigger of immune responses in different environments
Fragrances as a trigger of immune responses in different environments
Fragrances are mixtures of organic molecules, including esters, aldehydes and alcohols present in a plethora of products (...
ESTIV 2022: Key enabling non-animal technologies for research, education and testing
ESTIV 2022: Key enabling non-animal technologies for research, education and testing
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
A comparison of dermal toxicity models; assessing suitability for safe(r)-by-design decision-making and for screening nanomaterial hazards
A comparison of dermal toxicity models; assessing suitability for safe(r)-by-design decision-making and for screening nanomaterial hazards
KeywordsNanomaterialSafe-by-designHazard screeningDermal toxicityNew approach methodologies (NAMs)Data availabilityIt is p...
Using cell culture systems from the Persian Gulf Arabian yellowfin sea bream, Acanthopagrus arabicus, to assess the effects of dexamethasone on gonad and brain aromatase activity and steroid production
Using cell culture systems from the Persian Gulf Arabian yellowfin sea bream, Acanthopagrus arabicus, to assess the effects of dexamethasone on gonad and brain aromatase activity and steroid production
>4000 pharmaceutical compounds (PCs) up to hundreds of tons are commercially produced, many of which are designed to im...
Characterization of palmitic acid toxicity induced insulin resistance in HepG2 cells.
Characterization of palmitic acid toxicity induced insulin resistance in HepG2 cells.
Insulin is a peptide hormone that plays an important role in the regulation of carbohydrate, fat, and protein metabolism (...
Lovastatin impairs cellular proliferation and enhances hyaluronic acid production in fibroblast-like synoviocytes
Lovastatin impairs cellular proliferation and enhances hyaluronic acid production in fibroblast-like synoviocytes
Cholesterol metabolism is involved in the pathogenesis of osteoarthritis (OA), and a high cholesterol level has been ident...
Simulated gastric leachate of 3D printer metal-fill filaments induces cytotoxic effects in rat and human intestinal models
Simulated gastric leachate of 3D printer metal-fill filaments induces cytotoxic effects in rat and human intestinal models
Three-dimensional (3D) printing, also termed additive manufacturing, has advanced from a commercial industrial process to ...
Perfluorooctanoic acid inhibits cell proliferation through mitochondrial damage
Perfluorooctanoic acid inhibits cell proliferation through mitochondrial damage
Since its first production in 1947, perfluorooctanoic acid (PFOA) has been applied in extensive industrial fields, includi...
In vitro immunotoxicity effects of carbendazim were inhibited by n-acetylcysteine in microglial BV-2 cells
In vitro immunotoxicity effects of carbendazim were inhibited by n-acetylcysteine in microglial BV-2 cells
Among glial cells, microglia are major component of the central nervous system (CNS), and play central roles in neuroimmun...
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