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Effect of changes in skin properties due to diabetes mellitus on the titration period of transdermal fentanyl: single-center retrospective study and diabetic animal model study
Effect of changes in skin properties due to diabetes mellitus on the titration period of transdermal fentanyl: single-center retrospective study and diabetic animal model study
In the dose titration of transdermal fentanyl to prevent unrelieved pain, it is important to consider not only dose adjust...
Clinical characteristics of patients requiring emergency hospitalization due to immune-related adverse events: a retrospective study
Clinical characteristics of patients requiring emergency hospitalization due to immune-related adverse events: a retrospective study
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, offering hope for various malignancies by enhanc...
Comparison of continuous subcutaneous hydromorphone hydrochloride and morphine hydrochloride injection on skin disorders incidence: a retrospective study
Comparison of continuous subcutaneous hydromorphone hydrochloride and morphine hydrochloride injection on skin disorders incidence: a retrospective study
Continuous subcutaneous administration of injectable opioids is simple and effective; however, skin disorders may occur wh...
Influence of loop diuretics on denosumab-induced hypocalcaemia in osteoporosis: a retrospective observational analysis
Influence of loop diuretics on denosumab-induced hypocalcaemia in osteoporosis: a retrospective observational analysis
We examined whether denosumab-induced hypocalcaemia is evident in osteoporosis when given loop diuretics that pro...
Impact of automated pop-up alerts on simultaneous prescriptions of antimicrobial agents and metal cations
Impact of automated pop-up alerts on simultaneous prescriptions of antimicrobial agents and metal cations
Antimicrobial agents (AMAs) are essential for treating infections. A part of AMAs chelate with metal cations (MCs), reduci...
Assessing the effects of interprofessional education by hospital pharmacists on pharmaceutical students using a self-evaluation scale
Assessing the effects of interprofessional education by hospital pharmacists on pharmaceutical students using a self-evaluation scale
Understanding the roles and competencies of professions outside of one’s specialty is essential for providing effici...
Usefulness of driver’s eye movement measurement to detect potential risks under combined conditions of taking second-generation antihistamines and calling tasks
Usefulness of driver’s eye movement measurement to detect potential risks under combined conditions of taking second-generation antihistamines and calling tasks
Concerns persist regarding the potential reduction in driving performance due to taking second-generation antihistamines o...
Safety and efficacy of oxycodone for refractory dyspnea in end-stage heart failure patients with chronic kidney disease: a case series of eight patients
Safety and efficacy of oxycodone for refractory dyspnea in end-stage heart failure patients with chronic kidney disease: a case series of eight patients
Morphine is effective in palliative care for patients with end-stage heart failure; however, its use is avoided in patient...
A case of successful contribution of therapeutic drug monitoring of valganciclovir as the prophylaxis against cytomegalovirus infection in a lung transplant recipient
A case of successful contribution of therapeutic drug monitoring of valganciclovir as the prophylaxis against cytomegalovirus infection in a lung transplant recipient
Ganciclovir and its prodrug, valganciclovir, are first-line agents for cytomegalovirus infection prophylaxis after lung tr...
Association between roxadustat use and suppression of thyroid function: a systematic review and meta-analysis
Association between roxadustat use and suppression of thyroid function: a systematic review and meta-analysis
Based on several case reports and observational studies, there is a growing concern regarding the potential association be...
Evaluation of starch granules based on hydroxypropylcellulose as a substitute for excipient lactose
Evaluation of starch granules based on hydroxypropylcellulose as a substitute for excipient lactose
The improvement in flowability and adhesion of starch powder (SP) is essential for using starch as an excipient for lactos...
Case report of QT interval prolongation induced by anamorelin in an obese patient with non-small cell lung cancer
Case report of QT interval prolongation induced by anamorelin in an obese patient with non-small cell lung cancer
Anamorelin, a drug to treat cancer cachexia, binds to ghrelin receptors and improves body weight and appetite. In clinical...
Comparison of anticoagulation control and outcomes between usual medical care and pharmacist-led anticoagulation service in ambulatory patients taking warfarin at tertiary hospital in Ethiopia: a quasi-experimental study
Comparison of anticoagulation control and outcomes between usual medical care and pharmacist-led anticoagulation service in ambulatory patients taking warfarin at tertiary hospital in Ethiopia: a quasi-experimental study
We aimed to compare anticoagulation control and outcomes between usual medical care (UMC) and pharmacist-led anticoagulati...
Relationship between antihypertensive drug use and number of people with high blood pressure in FY 2018: a descriptive epidemiological study based on the National Database of Health Insurance Claims and Specific Health Checkups of Japan open data
Relationship between antihypertensive drug use and number of people with high blood pressure in FY 2018: a descriptive epidemiological study based on the National Database of Health Insurance Claims and Specific Health Checkups of Japan open data
In most countries barring Japan, antihypertensive drug use has been reported using the defined daily doses/1000 inhabitant...
Adherence of denosumab treatment for low bone mineral density in Japanese people living with HIV: a retrospective observational study
Adherence of denosumab treatment for low bone mineral density in Japanese people living with HIV: a retrospective observational study
Long-term care issues, specifically metabolic bone disorders, are a concern for people living with human immunodeficiency ...
Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem cell transplantation
Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem cell transplantation
Methotrexate (MTX) is used to treat graft-versus-host disease (GVHD) following allogeneic hematopoietic stem cell transpla...
Induction of CYP3A activity by dexamethasone may not be strong, even at high doses: insights from a case of tacrolimus co-administration
Induction of CYP3A activity by dexamethasone may not be strong, even at high doses: insights from a case of tacrolimus co-administration
Dexamethasone (DEX) induces CYP3A activity in a concentration-dependent manner. However, no study has examined changes in ...
Effect of rapid cefpodoxime disk screening for early detection of third-generation cephalosporin resistance in Escherichia coli and Klebsiella pneumoniae bacteremia
Effect of rapid cefpodoxime disk screening for early detection of third-generation cephalosporin resistance in Escherichia coli and Klebsiella pneumoniae bacteremia
Several methods have been reported for detecting resistance genes or phenotypic testing on the day of positive blood cultu...
Efficacy of combined use of Suvorexant and Ramelteon in preventing postoperative delirium: a retrospective comparative study
Efficacy of combined use of Suvorexant and Ramelteon in preventing postoperative delirium: a retrospective comparative study
Suvorexant and ramelteon have been presented as useful for preventing postoperative delirium. Previous studies reported on...
Recovery from indomethacin-induced gastrointestinal bleeding by treatment with teprenone
Recovery from indomethacin-induced gastrointestinal bleeding by treatment with teprenone
Gastrointestinal injuries caused by nonsteroidal anti-inflammatory drugs (NSAIDs) is a serious side effect in patients wit...
Heart failure drug classes and 30-day unplanned hospital readmission among patients with heart failure in Ethiopia
Heart failure drug classes and 30-day unplanned hospital readmission among patients with heart failure in Ethiopia
Drug therapy is a crucial aspect of heart failure management and has been shown to reduce morbidity and mortality in heart...
Trends in teicoplanin loading dose implementation from 2010 to 2019 and evaluation of safety and efficacy factors: a retrospective cohort study based on a Japanese administrative claims database
Trends in teicoplanin loading dose implementation from 2010 to 2019 and evaluation of safety and efficacy factors: a retrospective cohort study based on a Japanese administrative claims database
The loading dose of teicoplanin (TEIC) is recommended for implementation. However, there is significant discrepancy betwee...
Faculty publication trends in a Japanese national university: a diachronic document analysis
Faculty publication trends in a Japanese national university: a diachronic document analysis
We previously demonstrated that in a Japanese national university’s medical faculty, overall paper publication frequ...
Poor removal of tedizolid during continuous hemodiafiltration: experiments using an in vitro continuous hemodiafiltration model
Poor removal of tedizolid during continuous hemodiafiltration: experiments using an in vitro continuous hemodiafiltration model
Tedizolid is an oxazolidinone anti-MRSA drug with included in the National Health Insurance Drug Price List in 2018. The e...
Synovial fluid and plasma concentrations of tedizolid in patients with osteoarthritis infected with Staphylococcus aureus effectively determined with fluorescence detection
Synovial fluid and plasma concentrations of tedizolid in patients with osteoarthritis infected with Staphylococcus aureus effectively determined with fluorescence detection
Tedizolid is a new oxazolidinone antibiotic with high potency for the treatment of infections caused by methicillin-resist...
Evaluation of the clinical and quantitative performance of a practical HPLC-UV platform for in-hospital routine therapeutic drug monitoring of multiple drugs
Evaluation of the clinical and quantitative performance of a practical HPLC-UV platform for in-hospital routine therapeutic drug monitoring of multiple drugs
In-hospital therapeutic drug monitoring (TDM) requires a suitable quantification method for target drugs from the viewpoin...
Analysis of factors affecting pharmacists' ability to identify and solve problems
Analysis of factors affecting pharmacists' ability to identify and solve problems
Among Japanese pharmacists, there is a gap in their commitment to self-improvement and a possible gap in their ability to ...
A systematic review of sodium-glucose cotransporter 2 inhibitors and renal profiles among Japanese patients with type 2 diabetes mellitus
A systematic review of sodium-glucose cotransporter 2 inhibitors and renal profiles among Japanese patients with type 2 diabetes mellitus
We conducted a systematic review and meta-analysis to summarize the available literature and comprehensively appraise the ...
Significance of pharmacist intervention to oral antithrombotic therapy in the pharmaceutical outpatient clinic of cardiovascular internal medicine: a retrospective cohort study
Significance of pharmacist intervention to oral antithrombotic therapy in the pharmaceutical outpatient clinic of cardiovascular internal medicine: a retrospective cohort study
Optimised antithrombotic therapy requires clinical experience and an understanding of the current guidelines. This retrosp...
Differences in the growth of microorganisms depends on the type of semi-solid enteral nutritional supplements
Differences in the growth of microorganisms depends on the type of semi-solid enteral nutritional supplements
Enteral nutritional supplements are used in many medical facilities and home care, but require appropriate management beca...
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