SCI Abstract

search
+
Inpatient referrals to a specialist falls and syncope service: prevalence of STOPPFall FRIDs and review of deprescribing patterns
Inpatient referrals to a specialist falls and syncope service: prevalence of STOPPFall FRIDs and review of deprescribing patterns
Falls are the commonest cause of accidental death in older people and the most frequent reason for their presentation to h...
Association between sodium-glucose cotransporter-2 inhibitor and adverse events in patients with moderate to severe chronic kidney disease: a systematic review and meta-analysis of randomized controlled trials
Association between sodium-glucose cotransporter-2 inhibitor and adverse events in patients with moderate to severe chronic kidney disease: a systematic review and meta-analysis of randomized controlled trials
Although there is concern about the association of sodium-glucose cotransporter-2 inhibitor (SGLT2i) use with musculoskele...
Evaluating the safety and effectiveness of tolvaptan in patients with heart failure and renal impairment: a systematic review and meta-analysis
Evaluating the safety and effectiveness of tolvaptan in patients with heart failure and renal impairment: a systematic review and meta-analysis
Patients with heart failure and concomitant renal impairment are often prescribed loop diuretics, such as furosemide, as t...
Effects of drugs on the oxygen dissociation curve—a scoping review
Effects of drugs on the oxygen dissociation curve—a scoping review
The shape and position of the hemoglobin-oxygen dissociation curve (ODC) is of critical importance in medicine, as it dete...
The impact of age and renal function on the pharmacokinetics and protein binding characteristics of fludarabine in paediatric and adult patients undergoing allogeneic haematopoietic stem cell transplantation conditioning
The impact of age and renal function on the pharmacokinetics and protein binding characteristics of fludarabine in paediatric and adult patients undergoing allogeneic haematopoietic stem cell transplantation conditioning
To evaluate the population pharmacokinetics of unbound F-Ara-A (the circulating metabolite of fludarabine) in 211 patients...
Sodium-glucose cotransporter 2 inhibitors and renal cancer in the US FDA adverse event reporting system
Sodium-glucose cotransporter 2 inhibitors and renal cancer in the US FDA adverse event reporting system
Recent evidence suggests an association between sodium-glucose cotransporter 2 (SGLT2) inhibitors and a higher risk of ren...
Comment on “Use of statins and risks of ovarian, uterine, and cervical diseases: a cohort study in the UK Biobank”
Comment on “Use of statins and risks of ovarian, uterine, and cervical diseases: a cohort study in the UK Biobank”
Cite this articleChung, PY., Liao, KF. & Lai, SW. Comment on “Use of statins and risks of ovarian, uterine, and cervic...
Dose reduction and discontinuation due to the combination of CDK4/6 inhibitors and endocrine drugs: a systematic review and meta-analysis
Dose reduction and discontinuation due to the combination of CDK4/6 inhibitors and endocrine drugs: a systematic review and meta-analysis
With the widespread use of CDK4/6 inhibitors, the number of discontinuations and reductions due to adverse events is incre...
The cost-effectiveness analysis of semaglutide for the treatment of adult and adolescent patients with overweight and obesity: a systematic review
The cost-effectiveness analysis of semaglutide for the treatment of adult and adolescent patients with overweight and obesity: a systematic review
The present study aimed to systematically collect and synthesize available cost-effectiveness studies of semaglutide in pa...
Efficacy of tacrolimus versus cyclosporine after lung transplantation: an updated systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials
Efficacy of tacrolimus versus cyclosporine after lung transplantation: an updated systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials
Little data supports using tacrolimus versus cyclosporin for immunosuppression concerning acute rejection and bronchioliti...
Preventive effects of first-generation antihistamine on emergence agitation or delirium: a systematic review
Preventive effects of first-generation antihistamine on emergence agitation or delirium: a systematic review
The effects of first-generation antihistamines in preventing postoperative emergence agitation or delirium are unclear. De...
Evaluation of the predictive performance of an online voriconazole dose calculator in children
Evaluation of the predictive performance of an online voriconazole dose calculator in children
The dosing of voriconazole is challenging in pediatrics. One approach to improve the dosing is through the use of Bayesian...
A critical review on approaches to generate and validate virtual population for physiologically based pharmacokinetic models: Methodologies, case studies and way forward
A critical review on approaches to generate and validate virtual population for physiologically based pharmacokinetic models: Methodologies, case studies and way forward
In silico modeling and simulation techniques such as physiologically based pharmacokinetic (PBPK) and physiologically base...
Pharmacokinetics-pharmacodynamics of first-line antitubercular drugs: a comparative study in tuberculosis patients with and without concomitant diabetes mellitus
Pharmacokinetics-pharmacodynamics of first-line antitubercular drugs: a comparative study in tuberculosis patients with and without concomitant diabetes mellitus
To observe the variability in the plasma concentrations and pharmacokinetic-pharmacodynamic (PK-PD) profiles of first-line...
Efficacy and safety of ticagrelor monotherapy following a brief DAPT vs. prolonged 12-month DAPT in ACS patients post-PCI: a meta-analysis of RCTs
Efficacy and safety of ticagrelor monotherapy following a brief DAPT vs. prolonged 12-month DAPT in ACS patients post-PCI: a meta-analysis of RCTs
As per current guidelines, acute coronary syndrome (ACS) patients who undergo percutaneous coronary intervention (PCI) sho...
Estimation of linezolid exposure in patients with hepatic impairment using machine learning based on a population pharmacokinetic model
Estimation of linezolid exposure in patients with hepatic impairment using machine learning based on a population pharmacokinetic model
To investigate the pharmacokinetic changes of linezolid in patients with hepatic impairment and to explore a method to pre...
Assessment of body mass-related covariates for rifampicin pharmacokinetics in healthy Caucasian volunteers
Assessment of body mass-related covariates for rifampicin pharmacokinetics in healthy Caucasian volunteers
Currently, body weight-based dosing of rifampicin is recommended. But lately, fat-free mass (FFM) was reported to be super...
The safety and efficacy of bevacizumab in treatment of recurrent low-grade glioma: a systematic review and meta-analysis
The safety and efficacy of bevacizumab in treatment of recurrent low-grade glioma: a systematic review and meta-analysis
Central nervous system (CNS) tumors are among the most common malignancies in various age ranges. Low-grade glioma (LGG) c...
Reliability and validity of the Swedish indicator ‘Drugs that should be avoided in older people’—an appraisal of a set of potentially inappropriate medications
Reliability and validity of the Swedish indicator ‘Drugs that should be avoided in older people’—an appraisal of a set of potentially inappropriate medications
To analyse the reliability and validity of the Swedish indicator ‘Drugs that should be avoided in older people’...
Activities of clinical pharmacologists across Europe: A survey by the European association of clinical pharmacology and therapeutics
Activities of clinical pharmacologists across Europe: A survey by the European association of clinical pharmacology and therapeutics
In order to explore clinical pharmacology and therapeutics (CPT) teaching and practices across continental Europe, the Eur...
The polymorphisms of candidate pharmacokinetic and pharmacodynamic genes and their pharmacogenetic impacts on the effectiveness of risperidone maintenance therapy among Saudi children with autism
The polymorphisms of candidate pharmacokinetic and pharmacodynamic genes and their pharmacogenetic impacts on the effectiveness of risperidone maintenance therapy among Saudi children with autism
Antipsychotics, including risperidone (RIS), are frequently indicated for various autism spectrum disorder (ASD) manifesta...
Use of statins and risks of ovarian, uterine, and cervical diseases: a cohort study in the UK Biobank
Use of statins and risks of ovarian, uterine, and cervical diseases: a cohort study in the UK Biobank
To examine the associations between use of statins and risks of various ovarian, uterine, and cervical diseases, including...
Real-world characteristics and use patterns of patients treated with vericiguat: A nationwide longitudinal cohort study in Germany
Real-world characteristics and use patterns of patients treated with vericiguat: A nationwide longitudinal cohort study in Germany
Vericiguat reduced clinical endpoints in patients experiencing worsening heart failure in clinical trials, but its impleme...
The effect of concomitant beta-blocker use on survival in patients with metastatic renal cell carcinoma treated with a vascular endothelial growth factor receptor inhibitors in the first line
The effect of concomitant beta-blocker use on survival in patients with metastatic renal cell carcinoma treated with a vascular endothelial growth factor receptor inhibitors in the first line
Vascular endothelial growth factor (VEGF) inhibition is one of the cornerstones of treatment in the treatment of metastati...
Pharmacokinetics of polymyxin B in different populations: a systematic review
Pharmacokinetics of polymyxin B in different populations: a systematic review
Despite being clinically utilized for the treatment of infections, the limited therapeutic range of polymyxin B (PMB), alo...
Evaluation of methods measuring medication adherence in patients with polypharmacy: a longitudinal and patient perspective
Evaluation of methods measuring medication adherence in patients with polypharmacy: a longitudinal and patient perspective
To explore patients’ willingness to have medication adherence measured using different methods and evaluate the feas...
Impact of combined propranolol and oxytocin on the process and outcomes of labor: a meta-analysis of randomized controlled trials
Impact of combined propranolol and oxytocin on the process and outcomes of labor: a meta-analysis of randomized controlled trials
To systematically review the impact of propranolol combined with oxytocin on the process and outcomes of labor. A comprehe...
Tyrosine kinase inhibitor–induced hypothyroidism: mechanism and clinical implications
Tyrosine kinase inhibitor–induced hypothyroidism: mechanism and clinical implications
Since the first experimentally proven tyrosine kinase inhibitor (TKI) imatinib was introduced in the clinical setting, TKI...
Long-acting B-2 agonists (LABA) or long-acting muscarinic antagonists (LAMA): which one may be the first option in group A COPD patients?
Long-acting B-2 agonists (LABA) or long-acting muscarinic antagonists (LAMA): which one may be the first option in group A COPD patients?
Long-acting muscarinic antagonists (LAMA) or beta-2 agonists (LABA) have been recommended for symptom control in group A C...
The effects of drug-drug interaction on linezolid pharmacokinetics: A systematic review
The effects of drug-drug interaction on linezolid pharmacokinetics: A systematic review
Linezolid is a commonly used antibiotic in the clinical treatment of gram-positive bacterial infections. The impacts of dr...
Load More
format_indent_increase