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A deep dive into the orchard of health: Exploring the anti-cancer and anti-aging potential of apple polyphenols
Apples, a ubiquitous and beloved fruit, harbor a treasure trove of bioactive compounds, with apple polyphenols (APs) takin...
Method development for the determination of phosphine residues in foods
Phosphine (PH3) is a fumigant used for pest control of stored products and foods. In Taiwan, PH3 has the maximum residue l...
Within-trial cost-effectiveness of novel macrophage-regulating treatment on wound healing in patients with diabetic foot ulcers
An M1/M2 macrophage-regulating treatment, ON101 cream, has shown its superior healing efficacy for diabetic foot ulcers (D...
Xanthohumol as a potential therapeutic strategy for acute myeloid leukemia: Targeting the FLT3/SRPK1 signaling axis
Xanthohumol (XN) is an isoprene chalcone found in hops (Humulus lupulus L.), a food ingredient with a wide range of pharma...
Protective role of Hsian-tsao ethanol extract against body fat, serum lipid profiles, and hepatic lipid profiles in high-fat diet-fed rats
This study investigated the preventive effects of a 40% ethanol extract of Hsian-tsao (40EEHT) on obesity in high-fat diet...
Bacillus coagulans 198 and L-glutamine in combination attenuated intestinal mucositis in a 5-FU-induced BALB/c mouse model via modulation of gut microbial community structure and diversity
5-Fluorouracil (5-FU) disrupts intestinal cells and causes dysbiosis in the gut microbiota. This study explores the potent...
Aspergillosis: A comprehensive review of pathogenesis, drug resistance, and emerging therapeutics
Aspergillosis stands as a primary opportunistic fungal infection which mainly results from Aspergillus fumigatus events th...
Regulatory framework and challenges for live biotherapeutic products in Taiwan
Products containing live microorganisms may be classified as food or drugs depending on their intended use; live biotherap...
Jiao San Xian granule containing prebiotic alleviate functional dyspepsia by regulating intestinal flora and the secretion of inflammatory response
Jiao Sanxian (JSX) consists of three traditional Chinese medicine including charred hawthorn, malt and Liu Shen Qu, they a...
Integrating network analysis and experimental validation to reveal the ferroptosis-associated mechanism of velvet antler in the treatment of chronic atrophic gastritis
Chronic atrophic gastritis (CAG) is precancerosis with limited treatment options. This study investigated the therapeutic ...
In Vitro metabolic profiling of methylenedioxy-substituted synthetic cathinones for enhanced detection in urine sample analysis
Synthetic cathinones are a widely abused class of new psychoactive substances that pose significant challenges in forensic...
Ping-Chong-Jiang-Ni Formula effectively inhibits migration and invasion of endometriosis 12Z cell line via TRIP13
The Ping-Chong-Jiang-Ni Formula (PCJNF), a compound of Traditional Chinese Medicine (TCM), has demonstrated remarkable cli...
Evaluating the cost-effectiveness of atezolizumab-bevacizumab in advanced hepatocellular carcinoma: Insights from Taiwan
Following the observed significant improvements in overall survival and progression-free survival in clinical trials, the ...
Yiqi Yangyin Tongluo prescription targets lncRNA VIM-AS1 to regulate FOXK2/mTOR to promote autophagy and inhibit renal tubular epithelial cell apoptosis
Diabetic nephropathy (DN) is one dominating reason for death in diabetic patients, and its incidence is high. It has been ...
Mechanobactericidal Nanotopographies for food industry: A promising strategy for eradicating foodborne pathogens - progress and challenges
Nowadays, food preservation, quality maintenance, and safety are major emerging concerns in the food industry. Methods for...
Updates on the conversion of nanosuspensions to solid oral dosage forms
Pharmaceutical nanosuspensions, also called nanocrystals, are heterogeneous mainly aqueous dispersions of insoluble drug p...
Therapeutic approach of carbon nanotube: Revolutionize nanomaterial in biomedical and pharmaceutical sector
Carbon nanotubes (CNTs) has emerged as a promising nanomaterial with a wide range of potential applications due to their u...
Herbal nanoemulsions in cosmetic science: A comprehensive review of design, preparation, formulation, and characterization
The rapid development of delivery systems for cosmetics has revealed two critical challenges in the field: enhancing the s...
A novel selective medium for isolation of Limosilactobacillus reuteri from dietary supplements
Limosilactobacillus reuteri is a probiotic bacterium known for its numerous beneficial effects on human health and is comm...
Determination and validation of polycyclic aromatichydrocarbons (PAH4) in katsuobushi, plant-basedfood supplements, and cocoa bean shells using GC-MS/MS
Polycyclic aromatic hydrocarbons (PAHs) are primarily generated through the incomplete combustion or pyrolysis oforganic m...
The effects of fermentation by different species oflactic acid bacteria on betalains and polyphenol profile and in vitro bioactive potential of red beetroot juice
In the current study, the effects of fermentation by Lactobacillus acidophilus, Levilactobacillus brevis or Lactiplantibac...
Development and industrial application of geographical origin identification for Taiwanese oolong tea
Taiwanese oolong tea is renowned for its excellent quality and enjoys a prestigious reputation both domestically and inter...
Bitter acids from Humulus lupulus L. alleviate D-galactose induced osteoblastic senescence and bone loss via regulating AKT/mTOR-mediated autophagy
Bitter acids (BA) are main component of Humulus lupulus L. (hops). They are known for beer brewing and have various biolog...
Bio-inspired chitosan/polydopamine-nanoparticle based sorbent bead: A versatile platform for separation and HPLC analysis of tetracycline antibiotics from various sample matrix
This study introduces an innovative bio-based sorbent bead crafted by integrating chitosan (CS) biopolymers, Fe(NO3)3 and ...
Aromatic compounds and organic acids identified from Ganoderma formosanum exhibit synergistic anti-melanogenic effects
This study reveals the anti-tyrosinase activity of Ganoderma formosanum extracts, pinpointing compounds including gluconic...
Fluorescent “on–off–on” sensor based on N, P co-doped carbon nanoparticles for specific detection of Fe3+ and ascorbic acid
Ascorbic acid (AA) is used as a food additive for its antibacterial and antioxidant properties. However, excessive intake ...
Effectiveness of pharmacist-managed oncology ambulatory care for patients with non–small cell lung cancer in Taiwan
Non-small cell lung cancer (NSCLC) is commonly treated with tyrosine kinase inhibitors (TKIs). However, adverseevents from...
Cost-effectiveness analysis of pembrolizumab with chemotherapy for metastatic nonsquamous non-small cell lung cancer in Taiwan
This study was aimed to evaluate the cost-effectiveness of pembrolizumab with chemotherapy (pembrolizumabcombination thera...
Cinnamic acid lowers blood pressure and reversesvascular endothelial dysfunction in rats
Cinnamic acid (CA) possesses important cardiovascular effects such as cardioprotective, antiatherogenic, anti-hyperlipidem...
Alanine supplementation enhancing cordycepin production in Cordyceps militaris via upregulation of Cns2 and Cns3 genes expression levels
Cordycepin, a key bioactive compound produced by Cordyceps militaris, faces the challenge of low productivity forcommercia...
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