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Engineering the T6SS of Pseudomonas for targeted delivery of antibacterial and antifungal effectors
Engineering the T6SS of Pseudomonas for targeted delivery of antibacterial and antifungal effectors
Bacteria employ diverse molecular systems, such as the type VI secretion system (T6SS) to outcompete other microorganisms ...
Development of a CRISPR-based cytosine base editor for restriction-modification system inactivation to enhance transformation efficiency in Vibrio Sp. dhg
Development of a CRISPR-based cytosine base editor for restriction-modification system inactivation to enhance transformation efficiency in Vibrio Sp. dhg
Vibrio sp. dhg is a fast-growing, alginate-utilizing, marine bacterium being developed as a platform host for macroalgae b...
Termination sequence between an inducible promoter and ubiquitous chromatin opening element (UCOE) reduces gene expression leakage and silencing
Termination sequence between an inducible promoter and ubiquitous chromatin opening element (UCOE) reduces gene expression leakage and silencing
Inducible gene expression circuits enable precise control over target gene activation and are widely used in direct reprog...
Biomaterial-based chitosan nanohydrogel films: combination of Bistorta officinalis and Ca-doped carbon dots for improved blood clotting
Biomaterial-based chitosan nanohydrogel films: combination of Bistorta officinalis and Ca-doped carbon dots for improved blood clotting
Bleeding and traumatic injuries are still a major issue necessitating the development of advanced hemostatic materials tha...
Unsilencing a cryptic xylose metabolic pathway in Rhodococcus jostii RHA1 for efficient lipid production from lignocellulosic biomass
Unsilencing a cryptic xylose metabolic pathway in Rhodococcus jostii RHA1 for efficient lipid production from lignocellulosic biomass
Rhodococcus jostii RHA1 is an oleaginous bacterium that has attracted considerable attention due to its capacity to use di...
Chitosan biomineralized with ions-doped nano-hydroxyapatite tunes osteoblasts metabolism and DNA damage
Chitosan biomineralized with ions-doped nano-hydroxyapatite tunes osteoblasts metabolism and DNA damage
Hydroxyapatite (HA) is a bioceramic material widely used as a bone biomimetic substitute and can be synthesized by biomine...
Integrative analysis of gene expression, protein abundance, and metabolomic profiling elucidates complex relationships in chronic hyperglycemia-induced changes in human aortic smooth muscle cells
Integrative analysis of gene expression, protein abundance, and metabolomic profiling elucidates complex relationships in chronic hyperglycemia-induced changes in human aortic smooth muscle cells
Type 2 diabetes mellitus (T2DM) is a major public health concern with significant cardiovascular complications (CVD). Desp...
Biovalorization of whey waste as economic nutriment for mycogenic production of single cell oils with promising antibiofilm and anticancer potentiality
Biovalorization of whey waste as economic nutriment for mycogenic production of single cell oils with promising antibiofilm and anticancer potentiality
The production of value-added bio-compounds from rejuvenated sources and their recruitment for healthcare services are par...
Evaluating ATP testing for distribution system monitoring: comparison to HPC, impact of chlorine quenching, and hold time dependency
Evaluating ATP testing for distribution system monitoring: comparison to HPC, impact of chlorine quenching, and hold time dependency
Adenosine triphosphate (ATP) assays have a faster turnaround time and higher sensitivity than traditional cultivation meth...
Chitosan as a promising materials for the construction of nanocarriers for diabetic retinopathy: an updated review
Chitosan as a promising materials for the construction of nanocarriers for diabetic retinopathy: an updated review
Diabetic retinopathy (DR) is a condition that causes swelling of the blood vessels of the retina and leaks blood and fluid...
An innovative lab-scale production for a novel therapeutic DNA vaccine candidate against rheumatoid arthritis
An innovative lab-scale production for a novel therapeutic DNA vaccine candidate against rheumatoid arthritis
Recent therapeutic-plasmid DNA vaccine strategies for rheumatoid arthritis (RA) have significantly improved. Our pcDNA-CCO...
Structural and practical identifiability analysis in bioengineering: a beginner’s guide
Structural and practical identifiability analysis in bioengineering: a beginner’s guide
Advancements in digital technology have brought modelling to the forefront in many disciplines from healthcare to architec...
Construction and applications of the EOMA spheroid model of Kaposiform hemangioendothelioma
Construction and applications of the EOMA spheroid model of Kaposiform hemangioendothelioma
Kaposiform hemangioendothelioma (KHE) is a rare intermediate vascular tumor with unclear pathogenesis. Recently, three dim...
3D-printed nanohydroxyapatite/methylacrylylated silk fibroin scaffold for repairing rat skull defects
3D-printed nanohydroxyapatite/methylacrylylated silk fibroin scaffold for repairing rat skull defects
The repair of bone defects remains a major challenge in the clinic, and treatment requires bone grafts or bone replacement...
Systematic comparison of nonviral gene delivery strategies for efficient co-expression of two transgenes in human mesenchymal stem cells
Systematic comparison of nonviral gene delivery strategies for efficient co-expression of two transgenes in human mesenchymal stem cells
Human mesenchymal stem cells (hMSCs) are being researched for cell-based therapies due to a host of unique properties, how...
Challenges and progress of neurodrug: bioactivities, production and delivery strategies of nerve growth factor protein
Challenges and progress of neurodrug: bioactivities, production and delivery strategies of nerve growth factor protein
Nerve growth factor (NGF) is a vital cytokine that plays a crucial role in the development and regeneration of the nervous...
Research progress of biomimetic materials in oral medicine
Research progress of biomimetic materials in oral medicine
Biomimetic materials are able to mimic the structure and functional properties of native tissues especially natural oral t...
Discrimination between the effects of pulsed electrical stimulation and electrochemically conditioned medium on human osteoblasts
Discrimination between the effects of pulsed electrical stimulation and electrochemically conditioned medium on human osteoblasts
Electrical stimulation is used for enhanced bone fracture healing. Electrochemical processes occur during the electrical s...
Preparation and in vitro evaluation of biological agents based on Zinc-laponite- curcumin incorporated in alginate hydrogel
Preparation and in vitro evaluation of biological agents based on Zinc-laponite- curcumin incorporated in alginate hydrogel
Due to their outstanding structures and properties, three-dimensional (3D) hydrogels and nanoparticles have been widely st...
Bilayer osteochondral graft in rabbit xenogeneic transplantation model comprising sintered 3D-printed bioceramic and human adipose-derived stem cells laden biohydrogel
Bilayer osteochondral graft in rabbit xenogeneic transplantation model comprising sintered 3D-printed bioceramic and human adipose-derived stem cells laden biohydrogel
Reconstruction of severe osteochondral defects in articular cartilage and subchondral trabecular bone remains a challengin...
Follicular reconstruction and neo-oogenesis in xenotransplantation of human ovarian isolated cells derived from chemotherapy-induced POF patients
Follicular reconstruction and neo-oogenesis in xenotransplantation of human ovarian isolated cells derived from chemotherapy-induced POF patients
Developing new strategies to restore fertility in patients with chemotherapy-induced Premature Ovarian Failure (Chemo-POF)...
Dual-drug (Curcumin/Ciprofloxacin) loading and release from chitosan-based hydrogels embedded with magnetic Montmorillonite/Hyaluronic acid for enhancing wound healing
Dual-drug (Curcumin/Ciprofloxacin) loading and release from chitosan-based hydrogels embedded with magnetic Montmorillonite/Hyaluronic acid for enhancing wound healing
Montmorillonite (MMt) is extensively applied as an efficient drug-carrier in designing drug delivery systems (DDS) due to ...
Antler stem cell-derived exosomes promote regenerative wound healing via fibroblast-to-myofibroblast transition inhibition
Antler stem cell-derived exosomes promote regenerative wound healing via fibroblast-to-myofibroblast transition inhibition
The typical outcome of mammalian wound healing is scarring, a fibrotic process mediated by myofibroblast aggregation. Perf...
Label-free multimodal electro-thermo-mechanical (ETM) phenotyping as a novel biomarker to differentiate between normal, benign, and cancerous breast biopsy tissues
Label-free multimodal electro-thermo-mechanical (ETM) phenotyping as a novel biomarker to differentiate between normal, benign, and cancerous breast biopsy tissues
Technologies for quick and label-free diagnosis of malignancies from breast tissues have the potential to be a significant...
Seaweed-based alginate/hydroxyapatite composite for the effective removal of bacteria, cyanobacteria, algae, and crystal violet from water
Seaweed-based alginate/hydroxyapatite composite for the effective removal of bacteria, cyanobacteria, algae, and crystal violet from water
A novel cost-effective and multifunctional nanocomposite was developed based on sustainable macroalgae biomass. The brown ...
Engineered live bacteria as disease detection and diagnosis tools
Engineered live bacteria as disease detection and diagnosis tools
Sensitive and minimally invasive medical diagnostics are essential to the early detection of diseases, monitoring their pr...
Novel ultra-stretchable and self-healing crosslinked poly (ethylene oxide)-cationic guar gum hydrogel
Novel ultra-stretchable and self-healing crosslinked poly (ethylene oxide)-cationic guar gum hydrogel
Hydrogels are three-dimensional structures with specific features that render them useful for biomedical applications, suc...
The lyophilized chloroplasts store synthetic DARPin G3 as bioactive encapsulated organelles
The lyophilized chloroplasts store synthetic DARPin G3 as bioactive encapsulated organelles
The high cost of fermentation, purification, cold storage and transportation, short shelf life, and sterile delivery metho...
Biomolecular and cellular effects in skin wound healing: the association between ascorbic acid and hypoxia-induced factor
Biomolecular and cellular effects in skin wound healing: the association between ascorbic acid and hypoxia-induced factor
The skin serves as a barrier to protect the body from environmental microorganisms and is the largest tissue of the body a...
Biosynthesis of ternary NiCoFe2O4 nanoflowers: investigating their 3D structure and potential use in gene delivery
Biosynthesis of ternary NiCoFe2O4 nanoflowers: investigating their 3D structure and potential use in gene delivery
Multicomponent nanoparticle systems are known for their varied properties and functions, and have shown potential as gene ...
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