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Development of a checklist for cognitive assessment requirements (CARE) based on a Delphi consensus study
Development of a checklist for cognitive assessment requirements (CARE) based on a Delphi consensus study
Situational factors can influence cognitive performance and should be considered for conducting cognitive assessments. The...
The brainstem reticular formation pivots abnormal neural transmission in the course of Anorexia Nervosa
The brainstem reticular formation pivots abnormal neural transmission in the course of Anorexia Nervosa
Anorexia nervosa (AN) represents an eating disorder, which features the highest rate of mortality among all psychiatric di...
Surgery impairs glymphatic activity and cognitive function in aged mice
Surgery impairs glymphatic activity and cognitive function in aged mice
Delirium is a common complication in elderly surgical patients and is associated with an increased risk of dementia. Altho...
Developmental deficits, synapse and dendritic abnormalities in a Clcn4 KO autism mice model: endophenotypic target for ASD
Developmental deficits, synapse and dendritic abnormalities in a Clcn4 KO autism mice model: endophenotypic target for ASD
Autism spectrum disorder (ASD) is linked to ion channel dysfunction, including chloride voltage-gated channel-4 (CLCN4). W...
Behavioral and Psychological Symptoms (BPSD) in Alzheimer’s Disease (AD): Development and Treatment
Behavioral and Psychological Symptoms (BPSD) in Alzheimer’s Disease (AD): Development and Treatment
Behavioral and psychological symptoms of dementia (BPSD), such as agitation, apathy, and psychosis, are highly prevalent a...
Feasibility pilot of a novel coaching intervention to optimize cannabis use for chronic pain management among Veterans
Feasibility pilot of a novel coaching intervention to optimize cannabis use for chronic pain management among Veterans
Chronic pain is common among Veterans, some of whom use cannabis for pain. We conducted a feasibility pilot study of a nov...
Safety and Efficacy of Ecopipam in Patients with Tourette Syndrome: A Systematic Review and Meta-analysis
Safety and Efficacy of Ecopipam in Patients with Tourette Syndrome: A Systematic Review and Meta-analysis
Ecopipam is a selective antagonist of the dopamine D1 receptor, and its efficacy and safety have recently been explored in...
Adjunctive PCSK9 Inhibitor Evolocumab in the Prevention of Early Neurological Deterioration in Non-cardiogenic Acute Ischemic Stroke: A Multicenter, Prospective, Randomized, Open-Label, Clinical Trial
Adjunctive PCSK9 Inhibitor Evolocumab in the Prevention of Early Neurological Deterioration in Non-cardiogenic Acute Ischemic Stroke: A Multicenter, Prospective, Randomized, Open-Label, Clinical Trial
Early neurological deterioration (END) is associated with a poor prognosis in acute ischemic stroke (AIS). Effectively low...
Emerging Pharmacological Approaches for Psychosis and Agitation in Alzheimer’s Disease
Emerging Pharmacological Approaches for Psychosis and Agitation in Alzheimer’s Disease
Psychosis and agitation are among the most distressing neuropsychiatric symptoms (NPSs) of Alzheimer’s disease (AD),...
The Complex Relationship Between Cannabis Use and Mental Health: Considering the Influence of Cannabis Use Patterns and Individual Factors
The Complex Relationship Between Cannabis Use and Mental Health: Considering the Influence of Cannabis Use Patterns and Individual Factors
The relationship between cannabis use and mental health is complex, as studies often report seemingly contradictory findin...
Safety and Efficacy of Deutetrabenazine at High versus Lower Daily Dosages in the ARC-HD Study to Treat Chorea in Huntington Disease
Safety and Efficacy of Deutetrabenazine at High versus Lower Daily Dosages in the ARC-HD Study to Treat Chorea in Huntington Disease
Huntington disease (HD) is a progressive neurodegenerative disease that causes psychiatric and neurological symptoms, incl...
Parsing the Prospective Links from Externalizing and Internalizing Symptoms to Substance Use: A Systematic Review and Meta-Analysis
Parsing the Prospective Links from Externalizing and Internalizing Symptoms to Substance Use: A Systematic Review and Meta-Analysis
The purpose of this study was to systematically analyze the prospective relationships between externalizing and internaliz...
Efficacy of Cariprazine in the Psychosis Spectrum: A Systematic Review and Network Meta-Analysis of Randomised Controlled Trials in Schizophrenia and Bipolar Disorder
Efficacy of Cariprazine in the Psychosis Spectrum: A Systematic Review and Network Meta-Analysis of Randomised Controlled Trials in Schizophrenia and Bipolar Disorder
Psychosis represents one of the most challenging clinical presentations in psychiatry. Schizophrenia and bipolar disorder ...
Association between cannabis use and physical activity in the United States based on legalization and health status
Association between cannabis use and physical activity in the United States based on legalization and health status
Studies investigating the association between cannabis use and physical activity have had mixed results. This study provid...
Multi-omics profiling of DNA methylation and gene expression alterations in human cocaine use disorder
Multi-omics profiling of DNA methylation and gene expression alterations in human cocaine use disorder
Structural and functional changes of the brain are assumed to contribute to excessive cocaine intake, craving, and relapse...
A systematic review of unique methods for measuring discount rates
A systematic review of unique methods for measuring discount rates
Discount rates play a pivotal role in various fields, capturing the trade-off between present and future, influencing pred...
The Safety of Alcohol Pharmacotherapies in Pregnancy: A Scoping Review of Human and Animal Research
The Safety of Alcohol Pharmacotherapies in Pregnancy: A Scoping Review of Human and Animal Research
Alcohol pharmacotherapies pose unknown teratogenic risks in pregnancy and are therefore recommended to be avoided. This li...
Orexin mechanisms in the prelimbic cortex modulate the expression of contextual conditioned fear
Orexin mechanisms in the prelimbic cortex modulate the expression of contextual conditioned fear
Despite the existing anatomical and physiological evidence pointing to the involvement of orexinergic projections from the...
Nucleus reuniens: Modulating emotional overgeneralization in peri-adolescents with anxiety
Nucleus reuniens: Modulating emotional overgeneralization in peri-adolescents with anxiety
Anxiety affects 4.4-million children in the USA with an onset between childhood and adolescence, a period marked by neural...
Problem Solving in Dance/Movement Therapy Research: Developing an Intervention Protocol for Adults Living with Treatment Resistant Depression
Problem Solving in Dance/Movement Therapy Research: Developing an Intervention Protocol for Adults Living with Treatment Resistant Depression
Dance/movement therapy (DMT) research requires creative and innovative thinking; this paper includes two parts demonstrati...
Cutaneous Signs of Nutritional Deficiencies
Cutaneous Signs of Nutritional Deficiencies
This review article highlights cutaneous findings of nutritional deficiencies with a particular focus on conditions that i...
Cutaneous Signs of Internal Malignancy
Cutaneous Signs of Internal Malignancy
The risk of internal malignancies increases with age with approximately 60% of malignancies occurring in patients greater ...
Effect of the glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide on alcohol consumption in alcohol-preferring male vervet monkeys
Effect of the glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide on alcohol consumption in alcohol-preferring male vervet monkeys
Glucagon-like peptide-1 (GLP-1) receptor agonists reduce alcohol consumption in rodents and non-human primates. Semaglutid...
Inhibition of cortical synaptic transmission, behavioral nociceptive, and anxiodepressive-like responses by arecoline in adult mice
Inhibition of cortical synaptic transmission, behavioral nociceptive, and anxiodepressive-like responses by arecoline in adult mice
Areca nut, the seed of Areca catechu L., is one of the most widely consumed addictive substances in the world after nicoti...
Rapid induction of transdermal buprenorphine to subcutaneous extended-release buprenorphine for the treatment of opioid use disorder
Rapid induction of transdermal buprenorphine to subcutaneous extended-release buprenorphine for the treatment of opioid use disorder
Buprenorphine is an effective and safe treatment for opioid use disorder, but the requirement for moderate opioid withdraw...
Scopoletin mitigates maternal separation-induced anxiety-like and depression-like behaviors in male mice through modulation of the Sirt1/NF-κB pathway
Scopoletin mitigates maternal separation-induced anxiety-like and depression-like behaviors in male mice through modulation of the Sirt1/NF-κB pathway
Early-life maternal separation can lead to anxiety-like and depression-like behaviors in mice reared under maternal separa...
Nimodipine-associated standard dose reductions and neurologic outcomes after aneurysmal subarachnoid hemorrhage: the era of pharmacogenomics
Nimodipine-associated standard dose reductions and neurologic outcomes after aneurysmal subarachnoid hemorrhage: the era of pharmacogenomics
Nimodipine, an L-type cerebroselective calcium channel antagonist, is the only drug approved by the US Food and Drug Admin...
Semi-physiological Pharmacokinetic Model of Clozapine and Norclozapine in Healthy, Non-smoking Volunteers: The Impact of Race and Genetics
Semi-physiological Pharmacokinetic Model of Clozapine and Norclozapine in Healthy, Non-smoking Volunteers: The Impact of Race and Genetics
Clozapine is the medication of choice for treatment-resistant schizophrenia. However, it has a complex metabolism and unex...
A Framework for the Administration of Anti-amyloid Monoclonal Antibody Treatments in Early-Stage Alzheimer’s Disease
A Framework for the Administration of Anti-amyloid Monoclonal Antibody Treatments in Early-Stage Alzheimer’s Disease
The US Food and Drug Administration (FDA) approval of lecanemab for early-stage Alzheimer’s disease (AD) represents ...
Intervening in the Premonitory Phase to Prevent Migraine: Prospects for Pharmacotherapy
Intervening in the Premonitory Phase to Prevent Migraine: Prospects for Pharmacotherapy
Migraine is a common brain condition characterised by disabling attacks of headache with sensory sensitivities. Despite in...
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