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Role of the Thalamic Reticular Nucleus in Social Memory
Role of the Thalamic Reticular Nucleus in Social Memory
This highlight was supported by grants from the National Natural Science Foundation of China (32125018 and 32071005), Zhej...
A Novel Astrocyte-Neuron Interaction to Control Complex Animal Behavior
A Novel Astrocyte-Neuron Interaction to Control Complex Animal Behavior
Zhou X, Xiao Q, Liu Y, Chen S, Xu X, Zhang Z. Astrocyte-mediated regulation of BLAWFS1 neurons alleviates risk-assessment ...
Histamine H1 Receptor in Medial Septum Cholinergic Circuit: New Hope for Fear-related Disorders?
Histamine H1 Receptor in Medial Septum Cholinergic Circuit: New Hope for Fear-related Disorders?
Merians AN, Spiller T, Harpaz-Rotem I, Krystal JH, Pietrzak RH. Post-traumatic stress disorder. Med Clin North Am 2023, 10...
Neural Basis of Categorical Representations of Animal Body Silhouettes
Neural Basis of Categorical Representations of Animal Body Silhouettes
Neural activities differentiating bodies versus non-body stimuli have been identified in the occipitotemporal cortex of bo...
Spatiotemporal Mapping of the Oxytocin Receptor at Single-Cell Resolution in the Postnatally Developing Mouse Brain
Spatiotemporal Mapping of the Oxytocin Receptor at Single-Cell Resolution in the Postnatally Developing Mouse Brain
The oxytocin receptor (OXTR) has garnered increasing attention for its role in regulating both mature behaviors and brain ...
Triple-Target Inhibition of Cholinesterase, Amyloid Aggregation, and GSK3β to Ameliorate Cognitive Deficits and Neuropathology in the Triple-Transgenic Mouse Model of Alzheimer’s Disease
Triple-Target Inhibition of Cholinesterase, Amyloid Aggregation, and GSK3β to Ameliorate Cognitive Deficits and Neuropathology in the Triple-Transgenic Mouse Model of Alzheimer’s Disease
Alzheimer’s disease (AD) poses one of the most urgent medical challenges in the 21st century as it affects millions ...
Dysregulated Pathways During Pregnancy Predict Drug Candidates in Neurodevelopmental Disorders
Dysregulated Pathways During Pregnancy Predict Drug Candidates in Neurodevelopmental Disorders
Maternal health during pregnancy has a direct impact on the risk and severity of neurodevelopmental disorders (NDDs) in th...
Zona Incerta: A Bridge for Infant-Mother Interaction
Zona Incerta: A Bridge for Infant-Mother Interaction
This highlight was supported by grants from the National Natural Science Foundation of China (32125018, 32071005, and 3217...
Non-invasive Modulation of Deep Brain Nuclei by Temporal Interference Stimulation
Non-invasive Modulation of Deep Brain Nuclei by Temporal Interference Stimulation
Temporal interference (TI) is a form of stimulation that epitomizes an innovative and non-invasive approach for profound n...
Mapping Fear-Related Neural Activity and Circuitry Changes Following Prophylactic Administration of (R,S)-Ketamine and (2S,6S)-Hydroxynorketamine
Mapping Fear-Related Neural Activity and Circuitry Changes Following Prophylactic Administration of (R,S)-Ketamine and (2S,6S)-Hydroxynorketamine
Merians AN, Spiller T, Harpaz-Rotem I, Krystal JH, Pietrzak RH. Post-traumatic stress disorder. Med Clin N Am 2023, 107: 8...
Fto-dependent Vdac3 m6A Modification Regulates Neuronal Ferroptosis Induced by the Post-ICH Mass Effect and Transferrin
Fto-dependent Vdac3 m6A Modification Regulates Neuronal Ferroptosis Induced by the Post-ICH Mass Effect and Transferrin
During the hyperacute phase of intracerebral hemorrhage (ICH), the mass effect and blood components mechanically lead to b...
Bridge RNA-Guided Genetic Recombination Tools for Treating Neurodegenerative Nucleotide Repeat Disorders
Bridge RNA-Guided Genetic Recombination Tools for Treating Neurodegenerative Nucleotide Repeat Disorders
McClintock B. The origin and behavior of mutable loci in maize. Proc Natl Acad Sci U S A 1950, 36: 344–355.Article  CA...
Fibrinogen-tau Aggregates Exacerbate Tau Pathology and Memory Deficits in Alzheimer’s Disease Model Mice
Fibrinogen-tau Aggregates Exacerbate Tau Pathology and Memory Deficits in Alzheimer’s Disease Model Mice
Vascular damage plays a significant role in the onset and progression of Alzheimer’s disease (AD). However, the prec...
Embracing Internal States: A Review of Optimization of Repetitive Transcranial Magnetic Stimulation for Treating Depression
Embracing Internal States: A Review of Optimization of Repetitive Transcranial Magnetic Stimulation for Treating Depression
Repetitive transcranial magnetic stimulation (rTMS) is a rapid and effective therapy for major depressive disorder; howeve...
Cation Channel TMEM63A Autonomously Facilitates Oligodendrocyte Differentiation at an Early Stage
Cation Channel TMEM63A Autonomously Facilitates Oligodendrocyte Differentiation at an Early Stage
Accurate timing of myelination is crucial for the proper functioning of the central nervous system. Here, we identified a ...
Cortical Dysplasia Beyond mTOR: Cellular Senescence Takes a Toll
Cortical Dysplasia Beyond mTOR: Cellular Senescence Takes a Toll
Lamberink HJ, Otte WM, Blümcke I, Braun KPJ, European Epilepsy Brain Bank writing group, Study Group, et al. Seizure outco...
The Role of Neuroinflammation and Network Anomalies in Drug-Resistant Epilepsy
The Role of Neuroinflammation and Network Anomalies in Drug-Resistant Epilepsy
Epilepsy affects over 50 million people worldwide. Drug-resistant epilepsy (DRE) accounts for up to a third of these cases...
Cancer-Associated Fibroblasts Interact with Schwann Cells for Tumor Perineural Invasion by Oral Squamous Cell Carcinoma
Cancer-Associated Fibroblasts Interact with Schwann Cells for Tumor Perineural Invasion by Oral Squamous Cell Carcinoma
Perineural invasion (PNI) by tumor cells is a key phenotype of highly-invasive oral squamous cell carcinoma (OSCC). Since ...
Altered Cortical Information Interaction During Respiratory Events in Children with Obstructive Sleep Apnea-Hypopnea Syndrome
Altered Cortical Information Interaction During Respiratory Events in Children with Obstructive Sleep Apnea-Hypopnea Syndrome
Obstructive sleep apnea-hypopnea syndrome (OSAHS) significantly impairs children’s growth and cognition. This study ...
A Cysteinyl-tRNA Synthetase Mutation Causes Novel Autosomal-Dominant Inheritance of a Parkinsonism/Spinocerebellar-Ataxia Complex
A Cysteinyl-tRNA Synthetase Mutation Causes Novel Autosomal-Dominant Inheritance of a Parkinsonism/Spinocerebellar-Ataxia Complex
This study aimed to identify possible pathogenic genes in a 90-member family with a rare combination of multiple neurodege...
Disentangling the Hippocampal Projectome
Disentangling the Hippocampal Projectome
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishin...
A New Acquaintance of Oligodendrocyte Precursor Cells in the Central Nervous System
A New Acquaintance of Oligodendrocyte Precursor Cells in the Central Nervous System
Oligodendrocyte precursor cells (OPCs) are a heterogeneous multipotent population in the central nervous system (CNS) that...
Deletion of Luzp2 Does Not Cause Hearing Loss in Mice
Deletion of Luzp2 Does Not Cause Hearing Loss in Mice
Deafness is the prevailing sensory impairment among humans, impacting every aspect of one's existence. Half of congeni...
Correction to: Deletion of Luzp2 Does Not Cause Hearing Loss in Mice
Correction to: Deletion of Luzp2 Does Not Cause Hearing Loss in Mice
Department of Otolaryngology-Head and Neck Surgery, Drum Tower Hospital, Affiliated Hospital of the Medical School, Jiangs...
Inhibition of YIPF2 Improves the Vulnerability of Oligodendrocytes to Human Islet Amyloid Polypeptide
Inhibition of YIPF2 Improves the Vulnerability of Oligodendrocytes to Human Islet Amyloid Polypeptide
Excessive secretion of human islet amyloid polypeptide (hIAPP) is an important pathological basis of diabetic encephalopat...
Thalamic Nucleus Reuniens Glutamatergic Neurons Mediate Colorectal Visceral Pain in Mice via 5-HT2B Receptors
Thalamic Nucleus Reuniens Glutamatergic Neurons Mediate Colorectal Visceral Pain in Mice via 5-HT2B Receptors
Irritable bowel syndrome (IBS) is a common functional bowel disorder characterized by abdominal pain and visceral hypersen...
Development and Application of a Mitochondrial Genetically Encoded Voltage Indicator in Narcosis
Development and Application of a Mitochondrial Genetically Encoded Voltage Indicator in Narcosis
Mitochondrial membrane potential (MMP) plays a crucial role in the function of cells and organelles, involving various cel...
Putative Risk Biomarkers of Bipolar Disorder in At-risk Youth
Putative Risk Biomarkers of Bipolar Disorder in At-risk Youth
Bipolar disorder is a highly heritable and functionally impairing disease. The recognition and intervention of BD especial...
Sex-Differential Neural Circuits and Behavioral Responses for Empathy
Sex-Differential Neural Circuits and Behavioral Responses for Empathy
This research highlight was supported by grants from the National Natural Science Foundation of China (32125018 and 320710...
Loss of TET Activity in the Postnatal Mouse Brain Perturbs Synaptic Gene Expression and Impairs Cognitive Function
Loss of TET Activity in the Postnatal Mouse Brain Perturbs Synaptic Gene Expression and Impairs Cognitive Function
Conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) by ten-eleven translocation (TET) family proteins l...
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