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Lecanemab demonstrates highly selective binding to Aβ protofibrils isolated from Alzheimer's disease brains
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Ionic mechanisms involved in arginine vasopressin-mediated excitation of auditory cortical and thalamic neurons
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Sphingosine kinase 2 regulates protein ubiquitination networks in neurons
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Reduced platelet activation and thrombus formation in male transgenic model mice of Alzheimer's disease suggests early sex-specific differences in platelet pathophysiology
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Activation of angiotensin converting enzyme 2 promotes hippocampal neurogenesis via activation of Wnt/β-catenin signaling in hypertension
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iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death
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β2-adrenoceptor agonist formoterol attenuates NLRP3 inflammasome activation and GSDMD-mediated pyroptosis in microglia through enhancing IκBα/NF-κB inhibition, SQSTM1/p62-dependent selective autophagy and ESCRT-III-mediated plasma membrane repair
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Study on the involvement of microglial S100A8 in neuroinflammation and microglia activation during migraine attacks
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Interneurons in the CA1 stratum oriens expressing αTTP may play a role in the delayed-ageing Pol μ mouse model
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Cannabinoid receptor 2 agonist AM1241 alleviates epileptic seizures and epilepsy-associated depression via inhibiting neuroinflammation in a pilocarpine-induced chronic epilepsy mouse model
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Corrigendum to “Progress of reprogramming astrocytes into neuron” [Molecular and Cellular Neuroscience, Volume 130, September 2024, 103947, DOI: 10.1016/j.mcn.2024.103947]
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β-Hydroxybutyrate enhances astrocyte glutamate uptake through EAAT1 expression regulation
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Transcriptomic changes in the hypothalamus of mice with chronic migraine: Activation of pathways associated with neuropathic inflammation and central sensitization
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SUMOylation modulates mitochondrial dynamics in an in vitro rotenone model of Parkinson's disease
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Knockdown of BMP7 induced oligodendrocyte apoptosis, demyelination and motor function loss
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The neuroprotective effect of short-chain fatty acids against hypoxia-reperfusion injury
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Astrocytes initiate autophagic flux and maintain cell viability after internalizing non-active native extracellular α-synuclein
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Vulnerability of neurofilament-expressing neurons in frontotemporal dementia
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Inhibition of phosphodiesterase 10A mitigates neuronal injury by modulating apoptotic pathways in cold-induced traumatic brain injury
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TAT-PPA1 protects against oxidative stress-induced loss of dopaminergic neurons
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The exocyst subunit Sec15 is critical for proper synaptic development and function at the Drosophila NMJ
The exocyst subunit Sec15 is critical for proper synaptic development and function at the Drosophila NMJ
The exocyst protein complex is important for targeted vesicle fusion in a variety of cell types, however, its function in ...
Role and mechanism of EphB3 in epileptic seizures and epileptogenesis through Kalirin
Role and mechanism of EphB3 in epileptic seizures and epileptogenesis through Kalirin
BackgroundThe EphB receptor tyrosine kinase family participates in intricate signaling pathways that orchestrate neural ne...
Amyloid-β deposits in human astrocytes contain truncated and highly resistant proteoforms
Amyloid-β deposits in human astrocytes contain truncated and highly resistant proteoforms
Alzheimer's disease (AD) is a neurodegenerative disorder that develops over decades. Glial cells, including astrocytes are...
Alpha-synuclein pathology is associated with astrocyte senescence in a midbrain organoid model of familial Parkinson's disease
Alpha-synuclein pathology is associated with astrocyte senescence in a midbrain organoid model of familial Parkinson's disease
Volume 128, March 2024, 103919Author links open overlay panel, , , , , , Highlights•Patient specific midbrain organoids mo...
A neural mass model for disturbance of alpha rhythm in the minimal hepatic encephalopathy
A neural mass model for disturbance of alpha rhythm in the minimal hepatic encephalopathy
Hepatic encephalopathy (HE) is a spectrum of neuropsychiatric abnormalities associated with liver dysfunction, which is a ...
Plexin-B1 and Plexin-B2 play non-redundant roles in GABAergic synapse formation
Plexin-B1 and Plexin-B2 play non-redundant roles in GABAergic synapse formation
Proper circuit function in the mammalian brain relies upon cell-cell communication through two main types of chemical syna...
TREM2 in Alzheimer's disease: Structure, function, therapeutic prospects, and activation challenges
TREM2 in Alzheimer's disease: Structure, function, therapeutic prospects, and activation challenges
Triggering receptor expressed on myeloid cells 2 (TREM2) is a membrane glycoprotein that plays a crucial role in the regul...
Cdc42 activation is necessary for heterosynaptic cooperation and competition
Cdc42 activation is necessary for heterosynaptic cooperation and competition
Synapses change their weights in response to neuronal activity and in turn, neuronal networks alter their response propert...
Systemic inflammation activates coagulation and immune cell infiltration pathways in brains with propagating α-synuclein fibril aggregates
Systemic inflammation activates coagulation and immune cell infiltration pathways in brains with propagating α-synuclein fibril aggregates
Atp1a2ATPase Na+/K+ transporting subunit Alpha2Atp1b2ATPase Na+/K+ transporting subunit Beta2DlatMitochondrial dehydrogena...
Suppression of BMP signaling restores mitral cell development impaired by FGF signaling deficits in mouse olfactory bulb
Suppression of BMP signaling restores mitral cell development impaired by FGF signaling deficits in mouse olfactory bulb
The olfactory bulb (OB) is found in all vertebrates and is the first relay station of the olfactory information in the bra...
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