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Transient Receptor Potential (TRP) Channels in Cochlear Function: Looking Beyond Mechanotransduction
Transient Receptor Potential (TRP) Channels in Cochlear Function: Looking Beyond Mechanotransduction
Transient receptor potential (TRP) channels play key roles in sensory biology as transducers of various stimuli. Although ...
The Ins and Outs of Distortion Product Otoacoustic Emission Growth: A Review
The Ins and Outs of Distortion Product Otoacoustic Emission Growth: A Review
Otoacoustic emissions (OAEs) are low-level signals generated from active processes related to outer hair cell transduction...
Investigating the Effect of Blurring and Focusing Current in Cochlear Implant Users with the Panoramic ECAP Method
Investigating the Effect of Blurring and Focusing Current in Cochlear Implant Users with the Panoramic ECAP Method
For some cochlear implants (CIs), it is possible to focus electrical stimulation by partially returning current from the a...
Vital Dye Uptake of YO-PRO-1 and DASPEI Depends Upon Mechanoelectrical Transduction Function in Zebrafish Hair Cells
Vital Dye Uptake of YO-PRO-1 and DASPEI Depends Upon Mechanoelectrical Transduction Function in Zebrafish Hair Cells
Vital dyes allow the visualization of cells in vivo without causing tissue damage, making them a useful tool for studying ...
Tuning and Timing of Organ of Corti Vibrations at the Apex of the Intact Chinchilla Cochlea
Tuning and Timing of Organ of Corti Vibrations at the Apex of the Intact Chinchilla Cochlea
The goal of this research was to record sound-evoked vibrations in the organ of Corti at the apex of the intact cochlea of...
Evaluating the Correlation Between Stimulus Frequency Otoacoustic Emission Group Delays and Tuning Sharpness in a Cochlear Model
Evaluating the Correlation Between Stimulus Frequency Otoacoustic Emission Group Delays and Tuning Sharpness in a Cochlear Model
Purpose: A theoretical framework based on coherent reflection and filter theory predicts that the phase-gradient delays of...
What Do Mismatch Negativity (MMN) Responses Tell Us About Tinnitus?
What Do Mismatch Negativity (MMN) Responses Tell Us About Tinnitus?
Due to the heterogeneous causes, symptoms and associated comorbidities with tinnitus, there remains an unmet need for a cl...
Human Olivocochlear Effects: A Statistical Detection Approach Applied to the Cochlear Microphonic Evoked by Swept Tones
Human Olivocochlear Effects: A Statistical Detection Approach Applied to the Cochlear Microphonic Evoked by Swept Tones
The human medial olivocochlear (MOC) reflex was assessed by observing the effects of contralateral acoustic stimulation (C...
Experimental Study of Needle Insertion into Gerbil Tympanic Membrane
Experimental Study of Needle Insertion into Gerbil Tympanic Membrane
The perforation characteristics and fracture-related mechanical properties of the tympanic membrane (TM) greatly affect su...
The Origin Along the Cochlea of Otoacoustic Emissions Evoked by Mid-Frequency Tone Pips
The Origin Along the Cochlea of Otoacoustic Emissions Evoked by Mid-Frequency Tone Pips
Tone-pip-evoked otoacoustic emissions (PEOAEs) are transient-evoked otoacoustic emissions (OAEs) that are hypothesized to ...
Asymmetry in the Perception of Electrical Chirps Presented to Cochlear Implant Listeners
Asymmetry in the Perception of Electrical Chirps Presented to Cochlear Implant Listeners
Although a broadband acoustic click is physically the shortest duration sound we can hear, its peripheral neural represent...
Electron Microscopic Mapping of Mitochondrial Morphology in the Cochlear Nerve Fibers
Electron Microscopic Mapping of Mitochondrial Morphology in the Cochlear Nerve Fibers
To enable nervous system function, neurons are powered in a use-dependent manner by mitochondria undergoing morphological-...
DNA Methylation Patterns Associated with Tinnitus in Young Adults—A Pilot Study
DNA Methylation Patterns Associated with Tinnitus in Young Adults—A Pilot Study
Tinnitus, the perception of sound without any external sound source, is a prevalent hearing health concern. Mounting evide...
Enhanced Place Specificity of the Parallel Auditory Brainstem Response: An Electrophysiological Study
Enhanced Place Specificity of the Parallel Auditory Brainstem Response: An Electrophysiological Study
This study investigates the effect of parallel stimulus presentation on the place specificity of the auditory brainstem re...
Otoacoustic Estimate of Astronauts’ Intracranial Pressure Changes During Spaceflight
Otoacoustic Estimate of Astronauts’ Intracranial Pressure Changes During Spaceflight
To investigate the potential correlation between prolonged exposure to microgravity on the International Space Station and...
Cochlear Aqueduct Post-Natal Growth: A Computed Tomography Study
Cochlear Aqueduct Post-Natal Growth: A Computed Tomography Study
The cochlear aqueduct (CA) is a bony canal located at the base of the scala tympani of the cochlea. It connects the inner ...
Measuring Optokinetic Reflex and Vestibulo-Ocular Reflex in Unilateral Vestibular Organ Damage Model of Zebrafish
Measuring Optokinetic Reflex and Vestibulo-Ocular Reflex in Unilateral Vestibular Organ Damage Model of Zebrafish
One-sided vestibular disorders are common in clinical practice; however, their models have not been fully established. We ...
Swept Along: Measuring Otoacoustic Emissions Using Continuously Varying Stimuli
Swept Along: Measuring Otoacoustic Emissions Using Continuously Varying Stimuli
At the 2004 Midwinter Meeting of the Association for Research in Otolaryngology, Glenis Long and her colleagues introduced...
Exploring the Use of Interleaved Stimuli to Measure Cochlear-Implant Excitation Patterns
Exploring the Use of Interleaved Stimuli to Measure Cochlear-Implant Excitation Patterns
Attempts to use current-focussing strategies with cochlear implants (CI) to reduce neural spread-of-excitation have met wi...
Pneumococcal Meningitis Induces Hearing Loss and Cochlear Ossification Modulated by Chemokine Receptors CX3CR1 and CCR2
Pneumococcal Meningitis Induces Hearing Loss and Cochlear Ossification Modulated by Chemokine Receptors CX3CR1 and CCR2
Pneumococcal meningitis is a major cause of hearing loss and permanent neurological impairment despite widely available an...
Something in Our Ears Is Oscillating, but What? A Modeller’s View of Efforts to Model Spontaneous Emissions
Something in Our Ears Is Oscillating, but What? A Modeller’s View of Efforts to Model Spontaneous Emissions
When David Kemp discovered “spontaneous ear noise” in 1978, it opened up a whole new perspective on how the co...
SVPath: A Deep Learning Tool for Analysis of Stria Vascularis from Histology Slides
SVPath: A Deep Learning Tool for Analysis of Stria Vascularis from Histology Slides
The stria vascularis (SV) may have a significant role in various otologic pathologies. Currently, researchers manually seg...
Conditions Underlying the Appearance of Spontaneous Otoacoustic Emissions in Mammals
Conditions Underlying the Appearance of Spontaneous Otoacoustic Emissions in Mammals
Across the wide range of land vertebrate species, spontaneous otoacoustic emissions (SOAE) are common, but not always foun...
The Rapid Decline in Interaural-Time-Difference Sensitivity for Pure Tones Can Be Explained by Peripheral Filtering
The Rapid Decline in Interaural-Time-Difference Sensitivity for Pure Tones Can Be Explained by Peripheral Filtering
The interaural time difference (ITD) is a primary horizontal-plane sound localization cue computed in the auditory brainst...
Polygenic Risk Score-Based Association Analysis Identifies Genetic Comorbidities Associated with Age-Related Hearing Difficulty in Two Independent Samples
Polygenic Risk Score-Based Association Analysis Identifies Genetic Comorbidities Associated with Age-Related Hearing Difficulty in Two Independent Samples
Age-related hearing loss is the most common form of permanent hearing loss that is associated with various health traits, ...
Optimal Scale-Invariant Wavelet Representation and Filtering of Human Otoacoustic Emissions
Optimal Scale-Invariant Wavelet Representation and Filtering of Human Otoacoustic Emissions
Otoacoustic emissions (OAEs) are generated in the cochlea and recorded in the ear canal either as a time domain waveform o...
Hampshire Sheep as a Large-Animal Model for Cochlear Implantation
Hampshire Sheep as a Large-Animal Model for Cochlear Implantation
Sheep have been proposed as a large-animal model for studying cochlear implantation. However, prior sheep studies report t...
Echolocating Bats Have Evolved Decreased Susceptibility to Noise-Induced Temporary Hearing Losses
Echolocating Bats Have Evolved Decreased Susceptibility to Noise-Induced Temporary Hearing Losses
Glenis Long championed the application of quantitative psychophysical methods to understand comparative hearing abilities ...
Tinnitus in Children
Tinnitus in Children
This perspective reviews the current state of the art and literature on tinnitus in children, prevalence and risk factors,...
FDA-Approved Tedizolid Phosphate Prevents Cisplatin-Induced Hearing Loss Without Decreasing Its Anti-tumor Effect
FDA-Approved Tedizolid Phosphate Prevents Cisplatin-Induced Hearing Loss Without Decreasing Its Anti-tumor Effect
Cisplatin is a low-cost clinical anti-tumor drug widely used to treat solid tumors. However, its use could damage cochlear...
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