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Alpha-Synuclein Inhibits the Secretion of Extracellular Vesicles through Disruptions in YKT6 Lipidation
Alpha-Synuclein Inhibits the Secretion of Extracellular Vesicles through Disruptions in YKT6 Lipidation
Parkinson's disease is characterized by the presence of alpha-synuclein (α-syn) primarily containing Lewy bodies in neuron...
Neural Dynamics of the Processing of Speech Features: Evidence for a Progression of Features from Acoustic to Sentential Processing
Neural Dynamics of the Processing of Speech Features: Evidence for a Progression of Features from Acoustic to Sentential Processing
When we listen to speech, our brain’s neurophysiological responses “track” its acoustic features, but it is less well unde...
Local Regulation of Striatal Dopamine Release Shifts from Predominantly Cholinergic in Mice to GABAergic in Macaques
Local Regulation of Striatal Dopamine Release Shifts from Predominantly Cholinergic in Mice to GABAergic in Macaques
IntroductionDopamine projections to the striatum underlie many important functions, including movement control and reinfor...
The Temporal Organization of Learned Vocal Behavior Is Predicted by Species Rather Than Experience
The Temporal Organization of Learned Vocal Behavior Is Predicted by Species Rather Than Experience
Birdsong is hierarchically organized in time, like speech and other communication behaviors. Syllables are produced in seq...
Prioritizing Working Memory Resources Depends on the Prefrontal Cortex
Prioritizing Working Memory Resources Depends on the Prefrontal Cortex
How the prefrontal cortex contributes to working memory remains controversial, as theories differ in their emphasis on its...
Pallidothalamic Circuit-Selective Manipulation Ameliorates Motor Symptoms in a Rat Model of Parkinsonian
Pallidothalamic Circuit-Selective Manipulation Ameliorates Motor Symptoms in a Rat Model of Parkinsonian
Deep brain stimulation (DBS) effectively treats motor symptoms of advanced Parkinson's disease (PD), with the globus palli...
Compromising Tyrosine Hydroxylase Function Extends and Blunts the Temporal Profile of Reinforcement by Dopamine Neurons in Drosophila
Compromising Tyrosine Hydroxylase Function Extends and Blunts the Temporal Profile of Reinforcement by Dopamine Neurons in Drosophila
For a proper representation of the causal structure of the world, it is adaptive to consider both evidence for and evidenc...
Reference Frames for Encoding of Translation and Tilt in the Caudal Cerebellar Vermis
Reference Frames for Encoding of Translation and Tilt in the Caudal Cerebellar Vermis
Many daily behaviors rely on estimates of our body's motion and orientation in space. Vestibular signals are essential for...
Does Amplitude Compression Help or Hinder Attentional Neural Speech Tracking?
Does Amplitude Compression Help or Hinder Attentional Neural Speech Tracking?
Amplitude compression is an indispensable feature of contemporary audio production and especially relevant in modern heari...
Erratum: Navarri et al., "Cells and Molecules Underpinning Cannabis-Related Variations in Cortical Thickness during Adolescence"
Erratum: Navarri et al., "Cells and Molecules Underpinning Cannabis-Related Variations in Cortical Thickness during Adolescence"
In the article, “Cells and Molecules Underpinning Cannabis-Related Variations in Cortical Thickness during Adolescence” by...
Retraction: Larson et al., "The Complex PrPc-Fyn Couples Human Oligomeric A{beta} with Pathological Tau Changes in Alzheimers Disease"
Retraction: Larson et al., "The Complex PrPc-Fyn Couples Human Oligomeric A{beta} with Pathological Tau Changes in Alzheimers Disease"
The Editorial Board is retracting the article “The Complex PrPc-Fyn Couples Human Oligomeric Aβ with Pathological Tau Chan...
Retraction: Larson et al., "Soluble {alpha}-Synuclein is a Novel Modulator of Alzheimers Disease Pathophysiology"
Retraction: Larson et al., "Soluble {alpha}-Synuclein is a Novel Modulator of Alzheimers Disease Pathophysiology"
The Editorial Board is retracting the article “Soluble α-synuclein is a novel modulator of Alzheimer’s disease pathophysio...
Erratum: DNA G-Quadruplex Is a Transcriptional Control Device That Regulates Memory
Erratum: DNA G-Quadruplex Is a Transcriptional Control Device That Regulates Memory
In the article “DNA G-Quadruplex Is a Transcriptional Control Device That Regulates Memory,” by Paul R. Marshall, Joshua D...
Early Life Stress Impairs VTA Coordination of BLA Network and Behavioral States
Early Life Stress Impairs VTA Coordination of BLA Network and Behavioral States
AbstractMotivated behaviors, such as social interactions, are governed by the interplay between mesocorticolimbic structur...
Characterizing Olfactory Brain Responses in Young Infants
Characterizing Olfactory Brain Responses in Young Infants
Odor perception plays a critical role in early human development, but the underlying neural mechanisms are not fully under...
Astrocyte Modulation of Synaptic Plasticity Mediated by Activity-Dependent Sonic Hedgehog Signaling
Astrocyte Modulation of Synaptic Plasticity Mediated by Activity-Dependent Sonic Hedgehog Signaling
IntroductionActivity-dependent gene expression is a fundamental property of neurons by which they modify synapses in respo...
The Evolving Cerebellar and Cerebello-cortical Functional Connectivity Architecture during Infancy
The Evolving Cerebellar and Cerebello-cortical Functional Connectivity Architecture during Infancy
The conventional understanding of the cerebellum as a sole movement control center has become obsolete, given its role in ...
Local Differences in Network Organization in the Auditory and Parietal Cortex, Revealed with Single Neuron Activation
Local Differences in Network Organization in the Auditory and Parietal Cortex, Revealed with Single Neuron Activation
AbstractThe structure of local circuits is highly conserved across the cortex, yet the spatial and temporal properties of ...
Coronin1A Regulates the Trafficking of Alpha Synuclein in Microglia
Coronin1A Regulates the Trafficking of Alpha Synuclein in Microglia
Microglia respond to cytotoxic protein aggregates associated with the progression of neurodegenerative disease. Pathologic...
Neuregulin1 Nuclear Signaling Influences Adult Neurogenesis and Regulates a Schizophrenia Susceptibility Gene Network within the Mouse Dentate Gyrus
Neuregulin1 Nuclear Signaling Influences Adult Neurogenesis and Regulates a Schizophrenia Susceptibility Gene Network within the Mouse Dentate Gyrus
Generation of the Nrg1 V321L mutant mouse to study γ-secretase-mediated Nrg1 signalingNrg1 proteins can back signal throug...
PDE4B Missense Variant Increases Susceptibility to Post-traumatic Stress Disorder-Relevant Phenotypes in Mice
PDE4B Missense Variant Increases Susceptibility to Post-traumatic Stress Disorder-Relevant Phenotypes in Mice
AbstractLarge-scale genome-wide association studies (GWASs) have associated intronic variants in PDE4B, encoding cAMP-spec...
Distinct Neuron Types Contribute to Hybrid Auditory Spatial Coding
Distinct Neuron Types Contribute to Hybrid Auditory Spatial Coding
Neural decoding is a tool for understanding how activities from a population of neurons inside the brain relate to the out...
Sequential Activation of Lateral Hypothalamic Neuronal Populations during Feeding and Their Assembly by Gamma Oscillations
Sequential Activation of Lateral Hypothalamic Neuronal Populations during Feeding and Their Assembly by Gamma Oscillations
AbstractNeural circuits supporting innate behaviors, such as feeding, exploration, and social interaction, intermingle in ...
Coupling of Slow Oscillations in the Prefrontal and Motor Cortex Predicts Onset of Spindle Trains and Persistent Memory Reactivations
Coupling of Slow Oscillations in the Prefrontal and Motor Cortex Predicts Onset of Spindle Trains and Persistent Memory Reactivations
Sleep is known to drive the consolidation of motor memories. During nonrapid eye movement (NREM) sleep, the close temporal...
{mu}-Opioid Receptor Modulation of the Glutamatergic/GABAergic Midbrain Inputs to the Mouse Dorsal Hippocampus
{mu}-Opioid Receptor Modulation of the Glutamatergic/GABAergic Midbrain Inputs to the Mouse Dorsal Hippocampus
We used virus-mediated anterograde and retrograde tracing, optogenetic modulation, immunostaining, in situ hybridization, ...
Dynamic Organization of Neuronal Extracellular Matrix Revealed by HaloTag-HAPLN1
Dynamic Organization of Neuronal Extracellular Matrix Revealed by HaloTag-HAPLN1
The brain's extracellular matrix (ECM) regulates neuronal plasticity and animal behavior. ECM staining shows a net-like st...
Atp13a5 Marker Reveals Pericyte Specification in the Mouse Central Nervous System
Atp13a5 Marker Reveals Pericyte Specification in the Mouse Central Nervous System
AbstractPerivascular mural cells including vascular smooth cells (VSMCs) and pericytes are integral components of the vasc...
Beyond Barrels: Diverse Thalamocortical Projection Motifs in the Mouse Ventral Posterior Complex
Beyond Barrels: Diverse Thalamocortical Projection Motifs in the Mouse Ventral Posterior Complex
Thalamocortical pathways from the rodent ventral posterior (VP) thalamic complex to the somatosensory cerebral cortex area...
Spinal Cord Microglia in the Development of Touch
Spinal Cord Microglia in the Development of Touch
Adaptive interactions with environmental stressors are crucial to survival and are heavily reliant on detection and percep...
Erratum: Rosenberg et al., "{beta}-Adrenergic Signaling Promotes Morphological Maturation of Astrocytes in Female Mice"
Erratum: Rosenberg et al., "{beta}-Adrenergic Signaling Promotes Morphological Maturation of Astrocytes in Female Mice"
In the article “β-Adrenergic Signaling Promotes Morphological Maturation of Astrocytes in Female Mice,” by Marci F. Rosenb...
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