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Gene expression profiles of endothelium, microglia and oligodendrocytes in hippocampus of post-stroke depression rat at single cell resolution
Gene expression profiles of endothelium, microglia and oligodendrocytes in hippocampus of post-stroke depression rat at single cell resolution
Post-stroke depression (PSD) is a common but severe mental complication after stroke. However, the cellular and molecular ...
Neural stem and progenitor cells support and protect adult hippocampal function via vascular endothelial growth factor secretion
Neural stem and progenitor cells support and protect adult hippocampal function via vascular endothelial growth factor secretion
Adult neural stem and progenitor cells (NSPCs) reside in the dentate gyrus (DG) of the hippocampus throughout the lifespan...
Genome-wide copy number variation association study in anorexia nervosa
Genome-wide copy number variation association study in anorexia nervosa
This study represents the first large-scale investigation of rare (<1% population frequency) copy number variants (...
Age-related loss of large dendritic spines in the precuneus is statistically mediated by proteins which are predicted targets of existing drugs
Age-related loss of large dendritic spines in the precuneus is statistically mediated by proteins which are predicted targets of existing drugs
Preservation of dendritic spines is a putative mechanism of protection against cognitive impairment despite development of...
Respiratory disease in people with bipolar disorder: a systematic review and meta-analysis
Respiratory disease in people with bipolar disorder: a systematic review and meta-analysis
People with bipolar disorder (BD) have an increased risk of premature mortality and the respiratory mortality rate is high...
The role of co-occurring conditions and genetics in the associations of eating disorders with attention-deficit/hyperactivity disorder and autism spectrum disorder
The role of co-occurring conditions and genetics in the associations of eating disorders with attention-deficit/hyperactivity disorder and autism spectrum disorder
Eating disorders (EDs) commonly co-occur with other psychiatric and neurodevelopmental disorders including attention-defic...
ErbB inhibition rescues nigral dopamine neuron hyperactivity and repetitive behaviors in a mouse model of fragile X syndrome
ErbB inhibition rescues nigral dopamine neuron hyperactivity and repetitive behaviors in a mouse model of fragile X syndrome
Repetitive stereotyped behaviors are core symptoms of autism spectrum disorders (ASD) and fragile X syndrome (FXS), the pr...
Hippocampal area CA2 activity supports social investigation following an acute social stress
Hippocampal area CA2 activity supports social investigation following an acute social stress
Neuronal activity in the hippocampus is critical for many types of memory acquisition and retrieval and influences an anim...
Rasd2 regulates depression-like behaviors via DRD2 neurons in the prelimbic cortex afferent to nucleus accumbens core circuit
Rasd2 regulates depression-like behaviors via DRD2 neurons in the prelimbic cortex afferent to nucleus accumbens core circuit
Depressive symptoms, such as anhedonia, decreased social interaction, and lack of motivation, implicate brain reward syste...
Latent profiles of modifiable dementia risk factors in later midlife: relationships with incident dementia, cognition, and neuroimaging outcomes
Latent profiles of modifiable dementia risk factors in later midlife: relationships with incident dementia, cognition, and neuroimaging outcomes
In 2020, the Lancet Commission identified 12 modifiable factors that increase population-level dementia risk. It is unclea...
Single-cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2R47H Alzheimer’s risk gene mutation
Single-cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2R47H Alzheimer’s risk gene mutation
The R47H missense mutation of the TREM2 gene is a known risk factor for development of Alzheimer’s Disease. In this ...
Mapping the neurodevelopmental predictors of psychopathology
Mapping the neurodevelopmental predictors of psychopathology
Neuroimaging research has uncovered a multitude of neural abnormalities associated with psychopathology, but few predictio...
The universe is asymmetric, the mouse brain too
The universe is asymmetric, the mouse brain too
Hemispheric brain asymmetry is a basic organizational principle of the human brain and has been implicated in various psyc...
A meta-analysis of genome-wide studies of resilience in the German population
A meta-analysis of genome-wide studies of resilience in the German population
Resilience is the capacity to adapt to stressful life events. As such, this trait is associated with physical and mental f...
Deletion of murine astrocytic vesicular nucleotide transporter increases anxiety and depressive-like behavior and attenuates motivation for reward
Deletion of murine astrocytic vesicular nucleotide transporter increases anxiety and depressive-like behavior and attenuates motivation for reward
Astrocytes are multi-functional glial cells in the central nervous system that play critical roles in modulation of metabo...
Melatonin: A potential nighttime guardian against Alzheimer’s
Melatonin: A potential nighttime guardian against Alzheimer’s
In the context of the escalating global health challenge posed by Alzheimer’s disease (AD), this comprehensive revie...
Correction: Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression
Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USAMiklos Argyelan, Brian Angul...
Oxytocin activity in the paraventricular and supramammillary nuclei of the hypothalamus is essential for social recognition memory in rats
Oxytocin activity in the paraventricular and supramammillary nuclei of the hypothalamus is essential for social recognition memory in rats
Oxytocin plays an important role in modulating social recognition memory. However, the direct implication of oxytocin neur...
Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence
Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence
Maternal educational attainment (MEA) shapes offspring health through multiple potential pathways. Differential DNA methyl...
“Puberty age gap”: new method of assessing pubertal timing and its association with mental health problems
“Puberty age gap”: new method of assessing pubertal timing and its association with mental health problems
Puberty is linked to mental health problems during adolescence, and in particular, the timing of puberty is thought to be ...
Choroid plexus and perivascular space enlargement in neuropsychiatric systemic lupus erythematosus
Choroid plexus and perivascular space enlargement in neuropsychiatric systemic lupus erythematosus
Choroid plexus (CP) enlargement is proposed as a marker of neuroinflammation in immune-mediated conditions. CP involvement...
The neural signature of psychomotor disturbance in depression
The neural signature of psychomotor disturbance in depression
Up to 70% of patients with major depressive disorder present with psychomotor disturbance (PmD), but at the present time u...
Germline PTEN genotype-dependent phenotypic divergence during the early neural developmental process of forebrain organoids
Germline PTEN genotype-dependent phenotypic divergence during the early neural developmental process of forebrain organoids
PTEN germline mutations account for ~0.2–1% of all autism spectrum disorder (ASD) cases, as well as ~17% of ASD pati...
Molecular consequences of PQBP1 deficiency, involved in the X-linked Renpenning syndrome
Molecular consequences of PQBP1 deficiency, involved in the X-linked Renpenning syndrome
Mutations in the PQBP1 gene (polyglutamine-binding protein-1) are responsible for a syndromic X-linked form of neurodevelo...
The role of polyunsaturated fatty acids in the neurobiology of major depressive disorder and suicide risk
The role of polyunsaturated fatty acids in the neurobiology of major depressive disorder and suicide risk
Long-chain polyunsaturated fatty acids (LC-PUFAs) are obtained from diet or derived from essential shorter-chain fatty aci...
Microglia shape AgRP neuron postnatal development via regulating perineuronal net plasticity
Microglia shape AgRP neuron postnatal development via regulating perineuronal net plasticity
The hypothalamus plays a crucial role in controlling metabolism and energy balance, with Agouti-related protein (AgRP) neu...
Clarity on the blazing trail: clearing the way for amyloid-removing therapies for Alzheimer’s disease
Clarity on the blazing trail: clearing the way for amyloid-removing therapies for Alzheimer’s disease
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with a complex pathogenesis. Senile plaques com...
Intrinsic plasticity of Purkinje cell serves homeostatic regulation of fear memory
Intrinsic plasticity of Purkinje cell serves homeostatic regulation of fear memory
Two forms of plasticity, synaptic and intrinsic, are neural substrates for learning and memory. Abnormalities in homeostat...
Correction: Targeting NLRP3 inflammasome for neurodegenerative disorders
Correction to: Molecular Psychiatry, published online 5 September 2023In this article, an incorrect table...
Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression
Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression
Neurostimulation is a mainstream treatment option for major depression. Neuromodulation techniques apply repetitive magnet...
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