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Increased blood-brain barrier permeability is associated with dysfunctional α band connectivity in early-stage Parkinson’s disease
Increased blood-brain barrier permeability is associated with dysfunctional α band connectivity in early-stage Parkinson’s disease
The blood-brain barrier (BBB) is disrupted in Parkinson’s disease (PD); however, whether its alteration precedes neu...
Motor and non-motor features in progressive supranuclear palsy: the impact of microtubule associated protein tau haplotypes among a Tunisian cohort
Motor and non-motor features in progressive supranuclear palsy: the impact of microtubule associated protein tau haplotypes among a Tunisian cohort
Progressive supranuclear palsy (PSP) is a neurodegenerative disorder that impacts movement and cognition,caused by abnorma...
Olfaction function improves in a specialised unit for Parkinson’s disease
Olfaction function improves in a specialised unit for Parkinson’s disease
In-patient treatment of patients with Parkinson’s disease is common in specialized units. Reports on the efficacy of...
The effect of recombinant botulinum neurotoxin A on neuropathic pain in the spared nerve injury mouse model
The effect of recombinant botulinum neurotoxin A on neuropathic pain in the spared nerve injury mouse model
Neuropathic pain following traumatic nerve injury is a disabling chronic pain disorder characterized by sensory abnormalit...
Opicapone in Parkinson’s disease: a real-world, multicenter, retrospective study to identify patient characteristics for sustained treatment benefit
Opicapone in Parkinson’s disease: a real-world, multicenter, retrospective study to identify patient characteristics for sustained treatment benefit
Fluctuations often complicate the course of Parkinson’s disease (PD). The third-generation catechol-O-methyltransfer...
COMT inhibition with entacapone for patients with Parkinson’s disease and motor complications: the novelty of continuous infusion
COMT inhibition with entacapone for patients with Parkinson’s disease and motor complications: the novelty of continuous infusion
Enhancing levodopa efficacy through peripheral COMT inhibition and using continuous infusion are both established strategi...
State-dependent reactivity of anterior cingulate cortex neurochemistry and downstream autonomic arousal in intrusive thinking
State-dependent reactivity of anterior cingulate cortex neurochemistry and downstream autonomic arousal in intrusive thinking
Unwanted intrusive thoughts play a key role in the onset, maintenance, and relapse of stress-related psychopathological co...
Pharmacotherapy for psychiatric inpatients with alcohol use disorder or acute intoxication: results from an observational pharmacovigilance program—status and changes between 2000 and 2016
Pharmacotherapy for psychiatric inpatients with alcohol use disorder or acute intoxication: results from an observational pharmacovigilance program—status and changes between 2000 and 2016
Alcohol use disorder (AUD) is a mental disorder with a high prevalence and is one of the most common diagnoses requiring i...
Revisiting Parkinson’s disease definition and classification: insights from two emerging biological frameworks
Revisiting Parkinson’s disease definition and classification: insights from two emerging biological frameworks
Parkinson’s disease (PD) is increasingly recognized as a heterogeneous neurodegenerative entity with diverse clinica...
Challenges in the treatment of Tourette syndrome in the Philippines
Challenges in the treatment of Tourette syndrome in the Philippines
Tourette Syndrome (TS), the most recognized primary tic disorder, affects about 0.9% of patients in movement disorders cli...
Language dysfunction as a primary feature of cognitive decline in neurological populations
Language dysfunction as a primary feature of cognitive decline in neurological populations
Cognitive decline is a common feature of neurologic conditions, with language functions often affected. Word finding diffi...
MRI markers of neuroinflammation in untreated patients with subclinical generalized anxiety disorder
MRI markers of neuroinflammation in untreated patients with subclinical generalized anxiety disorder
Generalized Anxiety Disorder (GAD) is characterized by excessive worry and physical symptoms of prolonged anxiety. Patient...
Tiredness/fatigue and sexuality in everyday life: Findings from an ecological momentary assessment
Tiredness/fatigue and sexuality in everyday life: Findings from an ecological momentary assessment
Tiredness may be associated with increased or decreased sexual experience and behavior while fatigue seems to have a predo...
In-vivo evidence of synucleinopathy in parkinsonism due to VCP mutation
In-vivo evidence of synucleinopathy in parkinsonism due to VCP mutation
Multisystem proteinopathy 1 (MSP1) is a rare autosomal dominant disorder caused by mutations in the valosin-containing pro...
“Dozing off” in the car and excessive daytime sleepiness (EDS) in Parkinson’s disease: a survey of 125 patients
“Dozing off” in the car and excessive daytime sleepiness (EDS) in Parkinson’s disease: a survey of 125 patients
Parkinson’s disease patients are at increased risk of road traffic and car accidents and those with excessive daytim...
Impulsivity in cerebellar ataxia: an online, multidimensional assessment
Impulsivity in cerebellar ataxia: an online, multidimensional assessment
While considered a motor control structure, the cerebellum contributes to non-motor functions, including impulsivity. Howe...
Effects of opioid blockade on taste perception across smoking status: an analysis of detection thresholds, intensity, and pleasantness
Effects of opioid blockade on taste perception across smoking status: an analysis of detection thresholds, intensity, and pleasantness
The endogenous opioid system (EOS) is a neuromodulator of taste, and nicotine can modify both EOS signaling and taste perc...
Regulation of circadian gene activity in fibroblasts from ADHD patients through Rosiglitazone: a pilot study
Regulation of circadian gene activity in fibroblasts from ADHD patients through Rosiglitazone: a pilot study
Attention-deficit/hyperactivity disorder (ADHD) is a frequently observed condition, with about 70% of individuals diagnose...
Therapeutic drug monitoring in children and adolescents with schizophrenia-spectrum, affective, behavioural, tic and other psychiatric disorders treated with aripiprazole: results of the TDM-VIGIL pharmacovigilance study
Therapeutic drug monitoring in children and adolescents with schizophrenia-spectrum, affective, behavioural, tic and other psychiatric disorders treated with aripiprazole: results of the TDM-VIGIL pharmacovigilance study
Aripiprazole is approved for various severe mental disorders in adults and adolescents. However, off-label prescribing is ...
Sex-specific associations between 10-year cardiovascular risk, clinical symptoms and cognitive impairments in schizophrenia
Sex-specific associations between 10-year cardiovascular risk, clinical symptoms and cognitive impairments in schizophrenia
Schizophrenia (SCZ) shortens life expectancy, with cardiovascular disease (CVD) as the leading cause of death. The links b...
The corticospinal tract in multiple sclerosis: correlation between cortical excitability and magnetic resonance imaging measures
The corticospinal tract in multiple sclerosis: correlation between cortical excitability and magnetic resonance imaging measures
Multiple sclerosis (MS) is a central nervous system disease involving gray and white matters. Transcranial magnetic stimul...
Cholinergic neurotransmission in the brain of streptozotocin-induced rat model of sporadic Alzheimer’s disease: long-term follow up
Cholinergic neurotransmission in the brain of streptozotocin-induced rat model of sporadic Alzheimer’s disease: long-term follow up
Rats treated intracerebroventricularly with streptozotocin (STZ-icv) develop pathologic features, which resemble those in ...
Camillo Golgi’s contributions to the anatomic basis of sensitivity in tendons
Camillo Golgi’s contributions to the anatomic basis of sensitivity in tendons
Between 1878 and 1880 Camillo Golgi, professor of Histology and General Pathology at the University of Pavia, studied the ...
Exploring transferability in psychiatric interventions: a conceptual framework
Exploring transferability in psychiatric interventions: a conceptual framework
The growing significance of generalization in psychiatric interventions stems from the need for effective and applicable t...
Predisposing factors to pattern change in cervical dystonia
Predisposing factors to pattern change in cervical dystonia
Background: Cervical dystonia (CD) patterns may change with Botulinum toxin (BoNT) treatment. Objective: To evaluate the t...
Atrophy of cerebellar lobule VI and primary motor cortex in cervical dystonia - a region of interest-based study
Atrophy of cerebellar lobule VI and primary motor cortex in cervical dystonia - a region of interest-based study
Recently, a network model of cervical dystonia (CD) has been adopted that implicates nodes and pathways involving cerebell...
TMEM119-positive microglial cells in cerebrospinal fluid, a potential new marker for neuroinflammatory response after aneurysmal subarachnoid hemorrhage
TMEM119-positive microglial cells in cerebrospinal fluid, a potential new marker for neuroinflammatory response after aneurysmal subarachnoid hemorrhage
Aneurysmal subarachnoid hemorrhage (aSAH) is a debilitating condition with significant morbidity and mortality rates. Desp...
Protein misfolding: understanding biology to classify and treat synucleinopathies
Protein misfolding: understanding biology to classify and treat synucleinopathies
Protein misfolding and aggregation is a major pathological hallmark in a variety of human conditions, including cancer, di...
Enigmatic intractable Epilepsy patients have antibodies that bind glutamate receptor peptides, kill neurons, damage the brain, and cause Generalized Tonic Clonic Seizures
Enigmatic intractable Epilepsy patients have antibodies that bind glutamate receptor peptides, kill neurons, damage the brain, and cause Generalized Tonic Clonic Seizures
Epilepsy affects 1–2% of the world population, is enigmatic in 30% of cases, and is often intractable, unresponsive ...
In situ stoichiometry amounts of p62 and poly-ubiquitin exceed the increase of alpha-synuclein during degeneration of catecholamine cells induced by autophagy inhibition in vitro
In situ stoichiometry amounts of p62 and poly-ubiquitin exceed the increase of alpha-synuclein during degeneration of catecholamine cells induced by autophagy inhibition in vitro
Neurodegenerative disorders are typically featured by the occurrence of neuronal inclusions. In the case of Parkinson̵...
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