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Association of the triglyceride-glucose index combined with a body shape index with all-cause and cardiovascular mortality in individuals with cardiovascular-kidney-metabolic syndrome stage 0–3: findings from two prospective cohorts
Association of the triglyceride-glucose index combined with a body shape index with all-cause and cardiovascular mortality in individuals with cardiovascular-kidney-metabolic syndrome stage 0–3: findings from two prospective cohorts
The triglyceride-glucose (TyG) index, as a measure of insulin resistance, has been confirmed to be associated with adverse...
Fixed-dose vs loose-dose combination antidiabetic therapy and cardiorenal outcomes in type 2 diabetes: a nationwide comparative effectiveness study
Fixed-dose vs loose-dose combination antidiabetic therapy and cardiorenal outcomes in type 2 diabetes: a nationwide comparative effectiveness study
Combination therapy is gaining attention in type 2 diabetes management due to its potential to reach glycaemic goals withi...
Treatment and associated outcomes of type 2 diabetes mellitus patients with a cardiovascular comorbidity and comparison with guideline recommendations: a German claims data analysis
Treatment and associated outcomes of type 2 diabetes mellitus patients with a cardiovascular comorbidity and comparison with guideline recommendations: a German claims data analysis
Type 2 diabetes mellitus (T2DM) patients are at high risk for micro- and macrovascular complications, and cardiovascular (...
The association between triglyceride-glucose index and all-cause/cardiovascular mortality in patients with different glucose metabolism statuses
The association between triglyceride-glucose index and all-cause/cardiovascular mortality in patients with different glucose metabolism statuses
The triglyceride-glucose index (TyG) is an emerging marker of metabolic health, yet its association with mortality across ...
Association between the GMI/HbA1c ratio and preclinical carotid atherosclerosis in type 1 diabetes: impact of the fast-glycator phenotype across age groups
Association between the GMI/HbA1c ratio and preclinical carotid atherosclerosis in type 1 diabetes: impact of the fast-glycator phenotype across age groups
Since the arrival of continuous glucose monitoring (CGM), the relationship between the glucose management indicator (GMI) ...
Cardiac autonomic neuropathy is associated with ectopic fat distribution in autoimmune but not in type 2 diabetes
Cardiac autonomic neuropathy is associated with ectopic fat distribution in autoimmune but not in type 2 diabetes
Cardiac autonomic neuropathy (CAN) is a life-threatening complication of diabetes. While obesity is a well-known risk fact...
Association between the systemic immune-inflammation index and metabolic syndrome and its components: results from the multi-ethnic study of atherosclerosis (MESA)
Association between the systemic immune-inflammation index and metabolic syndrome and its components: results from the multi-ethnic study of atherosclerosis (MESA)
The Systemic Immune-Inflammation Index (SII) is a novel biomarker of systemic inflammation. We explored the association be...
Predicting major adverse cardiac events in diabetes and chronic kidney disease: a machine learning study from the Silesia Diabetes-Heart Project
Predicting major adverse cardiac events in diabetes and chronic kidney disease: a machine learning study from the Silesia Diabetes-Heart Project
People living with diabetes mellitus (DM) and chronic kidney disease (CKD) are at significantly high risk of cardiovascula...
Stress hyperglycemia ratio and machine learning model for prediction of all-cause mortality in patients undergoing cardiac surgery
Stress hyperglycemia ratio and machine learning model for prediction of all-cause mortality in patients undergoing cardiac surgery
The stress hyperglycemia ratio (SHR) was developed to reduce the effects of long-term chronic glycemic factors on stress h...
Endothelial cells derived extracellular vesicles promote diabetic arterial calcification via circ_0008362/miR-1251-5p/Runx2 axial
Endothelial cells derived extracellular vesicles promote diabetic arterial calcification via circ_0008362/miR-1251-5p/Runx2 axial
Arterial calcification, an independent predictor of cardiovascular events, increases morbidity and mortality in patients w...
Reduced circulating CD63+ extracellular vesicle levels associate with atherosclerosis in hypercholesterolaemic mice and humans
Reduced circulating CD63+ extracellular vesicle levels associate with atherosclerosis in hypercholesterolaemic mice and humans
The association and co-isolation of low-density lipoproteins (LDL) and extracellular vesicles (EVs) have been shown in blo...
Altered RBC deformability in diabetes: clinical characteristics and RBC pathophysiology
Altered RBC deformability in diabetes: clinical characteristics and RBC pathophysiology
Reduced red blood cell deformability (RBCD) is associated with diabetic vascular complications, but early pathophysiologic...
Impaired GK-GKRP interaction rather than direct GK activation worsens lipid profiles and contributes to long-term complications: a Mendelian randomization study
Impaired GK-GKRP interaction rather than direct GK activation worsens lipid profiles and contributes to long-term complications: a Mendelian randomization study
Glucokinase (GK) plays a key role in glucose metabolism. In the liver, GK is regulated by GK regulatory protein (GKRP) wit...
Roles of non-coding RNA in diabetic cardiomyopathy
Roles of non-coding RNA in diabetic cardiomyopathy
In recent years, the incidence of diabetes has been increasing rapidly, posing a serious threat to human health. Diabetic ...
Nonlinear association between atherogenic index of plasma and type 2 diabetes mellitus in overweight and obesity patients: evidence from Chinese medical examination data
Nonlinear association between atherogenic index of plasma and type 2 diabetes mellitus in overweight and obesity patients: evidence from Chinese medical examination data
The atherogenic index of plasma (AIP) is closely associated with the onset of diabetes, with obesity being a significant r...
Nonpharmacological interventions on glycated haemoglobin in youth with type 1 diabetes: a Bayesian network meta-analysis
Nonpharmacological interventions on glycated haemoglobin in youth with type 1 diabetes: a Bayesian network meta-analysis
The available evidence on the impact of specific non-pharmacological interventions on glycaemic control is currently limit...
Fatty liver index is an independent risk factor for all-cause mortality and major cardiovascular events in type 1 diabetes: an 11-year observational study
Fatty liver index is an independent risk factor for all-cause mortality and major cardiovascular events in type 1 diabetes: an 11-year observational study
Non-alcoholic fatty liver disease (NAFLD), identified by the Fatty Liver Index (FLI), is associated with increased mortali...
The prognostic value of the stress hyperglycemia ratio for all-cause and cardiovascular mortality in patients with diabetes or prediabetes: insights from NHANES 2005–2018
The prognostic value of the stress hyperglycemia ratio for all-cause and cardiovascular mortality in patients with diabetes or prediabetes: insights from NHANES 2005–2018
The Stress hyperglycemia ratio (SHR) is a novel marker reflecting the true acute hyperglycemia status and is associated wi...
The SGLT2 inhibitor Empagliflozin promotes post-stroke functional recovery in diabetic mice
The SGLT2 inhibitor Empagliflozin promotes post-stroke functional recovery in diabetic mice
Type-2 diabetes (T2D) worsens stroke recovery, amplifying post-stroke disabilities. Currently, there are no therapies targ...
Effects of exenatide on coronary stent’s endothelialization in subjects with type 2 diabetes: a randomized controlled trial. The Rebuild study
Effects of exenatide on coronary stent’s endothelialization in subjects with type 2 diabetes: a randomized controlled trial. The Rebuild study
Subjects with type 2 diabetes (T2D) have a higher risk of in-stent restenosis and stent thrombosis. The activation of the ...
Isthmin-1 (ISM1), a novel adipokine that reflects abdominal adipose tissue distribution in individuals with obesity
Isthmin-1 (ISM1), a novel adipokine that reflects abdominal adipose tissue distribution in individuals with obesity
The assessment of obesity-related health risks has traditionally relied on the Body Mass Index and waist circumference, bu...
Effects of diabetes mellitus and glycemic traits on cardiovascular morpho-functional phenotypes
Effects of diabetes mellitus and glycemic traits on cardiovascular morpho-functional phenotypes
The effects of diabetes on the cardiac and aortic structure and function remain unclear. Detecting and intervening these v...
Impact of stress hyperglycemia ratio, derived from glycated albumin or hemoglobin A1c, on mortality among ST-segment elevation myocardial infarction patients
Impact of stress hyperglycemia ratio, derived from glycated albumin or hemoglobin A1c, on mortality among ST-segment elevation myocardial infarction patients
Stress hyperglycemia ratio (SHR), associated with adverse outcomes in patients with ST-segment elevation myocardial infarc...
An elevated triglyceride-glucose index predicts adverse outcomes and interacts with the treatment strategy in patients with three-vessel disease
An elevated triglyceride-glucose index predicts adverse outcomes and interacts with the treatment strategy in patients with three-vessel disease
Insulin resistance is a pivotal risk factor for cardiovascular diseases, and the triglyceride-glucose (TyG) index is a wel...
Temporal relationship between triglyceride-glucose index and blood pressure and their joint cumulative effect on cardiovascular disease risk: a longitudinal cohort study
Temporal relationship between triglyceride-glucose index and blood pressure and their joint cumulative effect on cardiovascular disease risk: a longitudinal cohort study
Concurrent insulin resistance and elevated blood pressure are commonly observed in cardiovascular disease (CVD) and have l...
Cost-effectiveness of screening of coronary artery disease in patients with type 2 diabetes at a very high cardiovascular risk (SCADIAB) study. Updated study design: emulation of a randomised target trial using electronic health records
Cost-effectiveness of screening of coronary artery disease in patients with type 2 diabetes at a very high cardiovascular risk (SCADIAB) study. Updated study design: emulation of a randomised target trial using electronic health records
Type 2 diabetes mellitus (T2DM) is a substantial health problem with a high clinical and economic burden [1, 2]. Despite a...
Effects of dapagliflozin and dapagliflozin-saxagliptin on erythropoiesis, iron and inflammation markers in patients with type 2 diabetes and chronic kidney disease: data from the DELIGHT trial
Effects of dapagliflozin and dapagliflozin-saxagliptin on erythropoiesis, iron and inflammation markers in patients with type 2 diabetes and chronic kidney disease: data from the DELIGHT trial
This post-hoc analysis of the DELIGHT trial assessed effects of the SGLT2 inhibitor dapagliflozin on iron metabolism and m...
Cost-effectiveness of finerenone in chronic kidney disease associated with type 2 diabetes in The Netherlands
Cost-effectiveness of finerenone in chronic kidney disease associated with type 2 diabetes in The Netherlands
In the Netherlands, more than one million patients have type 2 diabetes (T2D), and approximately 36% of these patients hav...
Safety and efficacy of bempedoic acid: a systematic review and meta-analysis of randomised controlled trials
Safety and efficacy of bempedoic acid: a systematic review and meta-analysis of randomised controlled trials
Bempedoic Acid (BA) is a novel Lipid-Lowering Therapy (LLT). We performed a systematic review and meta-analysis to assess ...
Association between the triglyceride–glucose index and left ventricular global longitudinal strain in patients with coronary heart disease in Jilin Province, China: a cross-sectional study
Association between the triglyceride–glucose index and left ventricular global longitudinal strain in patients with coronary heart disease in Jilin Province, China: a cross-sectional study
This study aimed to investigate the association between the triglyceride–glucose (TyG) index and left ventricular gl...
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