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Identifying targetable metabolic dependencies across colorectal cancer progression
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Hepatic retinol dehydrogenase 11 dampens stress associated with the maintenance of cellular cholesterol levels
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miR-10a regulates cell death and inflammation in adipose tissue of male mice with diet-induced obesity
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Mammalian D-Cysteine controls insulin secretion in the pancreas
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Protein kinase D2 modulates hepatic insulin sensitivity in male mice
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Hypothalamic tanycytes internalize ghrelin from the cerebrospinal fluid: Molecular mechanisms and functional implications
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Distinct roles for the domains of the mitochondrial aspartate/glutamate carrier citrin in organellar localization and substrate transport
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Distinct genetic signals at the FGF21 locus complicate studies of FGF21's role in diet regulation using human cohort data
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A novel long non-coding RNA connects obesity to impaired adipocyte function
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FITM2 deficiency results in ER lipid accumulation, ER stress, and reduced apolipoprotein B lipidation and VLDL triglyceride secretion in vitro and in mouse liver
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TGF-β antagonism synergizes with PPARγ agonism to reduce fibrosis and enhance beige adipogenesis
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RNA-binding protein YBX3 promotes PPARγ-SLC3A2 mediated BCAA metabolism fueling brown adipogenesis and thermogenesis
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cAMP driven UCP1 induction in human adipocytes requires ATGL-catalyzed lipolysis
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Multi-omics after O-GlcNAc alteration identified cellular processes promoting aneuploidy after loss of O-GlcNAc transferase
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Macrophages on the run: Exercise balances macrophage polarization for improved health
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TOMM40 regulates hepatocellular and plasma lipid metabolism via an LXR-dependent pathway
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GLIS3: A novel transcriptional regulator of mitochondrial functions and metabolic reprogramming in postnatal kidney and polycystic kidney disease
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Linking metabolism and histone acetylation dynamics by integrated metabolic flux analysis of Acetyl-CoA and histone acetylation sites
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Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners
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Corrigendum to “The BBSome regulates mitochondria dynamics and function molecular metabolism” [Mol Metabol 67 (2023) 101654]
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VCD-induced menopause mouse model reveals reprogramming of hepatic metabolism
VCD-induced menopause mouse model reveals reprogramming of hepatic metabolism
ObjectiveMenopause adversely impacts systemic energy metabolism and increases the risk of metabolic disease(s) including h...
Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition
Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition
ObjectiveSkeletal muscle plasticity and remodeling are critical for adapting tissue function to use, disuse, and regenerat...
Adipose tissue peroxisomal lipid synthesis orchestrates obesity and insulin resistance through LXR-dependent lipogenesis
Adipose tissue peroxisomal lipid synthesis orchestrates obesity and insulin resistance through LXR-dependent lipogenesis
ObjectiveAdipose tissue mass is maintained by a balance between lipolysis and lipid storage. The contribution of adipose t...
Maternal exercise preserves offspring cardiovascular health via oxidative regulation of the ryanodine receptor
Maternal exercise preserves offspring cardiovascular health via oxidative regulation of the ryanodine receptor
ObjectiveThe intrauterine environment during pregnancy is a critical factor in the development of obesity, diabetes, and c...
Corrigendum to “Lack of Gαi2 proteins in adipocytes attenuates diet-induced obesity” [Mol Metab 40 (2020 Oct) 101029]
Corrigendum to “Lack of Gαi2 proteins in adipocytes attenuates diet-induced obesity” [Mol Metab 40 (2020 Oct) 101029]
Volume 82, April 2024, 101910Author links open overlay panelVeronika Leiss 1 9, Annika Schönsiegel 1 9, Thorsten Gnad 2, J...
Corrigendum to “Beta cell specific cannabinoid 1 receptor deletion counteracts progression to hyperglycemia in non-obese diabetic mice” [Mol Metab 82 (2024 April) 101906]
Corrigendum to “Beta cell specific cannabinoid 1 receptor deletion counteracts progression to hyperglycemia in non-obese diabetic mice” [Mol Metab 82 (2024 April) 101906]
Volume 82, April 2024, 101917Author links open overlay panelKanikkai Raja Aseer 1 2, Caio Henrique Mazucanti 1, Jennifer F...
Ablation of IFNγ in myeloid cells suppresses liver inflammation and fibrogenesis in mice with hepatic small heterodimer partner (SHP) deletion
Ablation of IFNγ in myeloid cells suppresses liver inflammation and fibrogenesis in mice with hepatic small heterodimer partner (SHP) deletion
BackgroundMetabolic dysfunction-associated steatotic liver disease (MASLD) is a common complication of obesity and in seve...
Mesenchymal-specific Alms1 knockout in mice recapitulates metabolic features of Alström syndrome
Mesenchymal-specific Alms1 knockout in mice recapitulates metabolic features of Alström syndrome
ObjectiveAlström Syndrome (AS), caused by biallelic ALMS1 mutations, includes obesity with disproportionately severe insul...
Corrigendum to “Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells” [Mol Metab 2016 May; 5 (5): 366–378]
Corrigendum to “Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells” [Mol Metab 2016 May; 5 (5): 366–378]
Available online 8 April 2024, 101935Author links open overlay panelTobias Boothe 1, Gareth E. Lim 1, Haoning Cen 1, Søs S...
Hepatic ketone body regulation of renal gluconeogenesis
Hepatic ketone body regulation of renal gluconeogenesis
Available online 9 April 2024, 101934Author links open overlay panel, , , , , , , , , Highlights•Renal gluconeogenic gene ...
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