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Multi-trait Genome-Wide Analysis Identified 20 Novel Loci for Sarcopenia-Related Traits in UK Biobank
Multi-trait Genome-Wide Analysis Identified 20 Novel Loci for Sarcopenia-Related Traits in UK Biobank
This study aims to identify novel loci associated with sarcopenia-related traits in UK Biobank (UKB) through multi-trait g...
Base of Skull & Spinal Canal Narrowing in an Adolescent with Autosomal Recessive Hypophosphatemic Rickets Type 2
Base of Skull & Spinal Canal Narrowing in an Adolescent with Autosomal Recessive Hypophosphatemic Rickets Type 2
Autosomal recessive hypophosphatemic rickets type 2 (ARHR2) is an uncommon hereditary form of rickets characterised by chr...
The Management of Bone Defects in Rett Syndrome
The Management of Bone Defects in Rett Syndrome
Rett syndrome (RS) is a rare neurodevelopmental disorder primarily caused by mutations in the X-linked methyl-CpG binding ...
Conflating the Operational Definition of Osteoporosis with Intervention Thresholds
Conflating the Operational Definition of Osteoporosis with Intervention Thresholds
Wáng YXJ, Griffith JF, Blake GM, Diacinti D, Xiao BH, Yu W, Su Y, Jiang Y, Guglielmi G, Guermazi A, Kwok TCY (2024) Revisi...
Treatment Advances in Tumor-Induced Osteomalacia
Treatment Advances in Tumor-Induced Osteomalacia
Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by hypersecretion of fibroblast growth factor 23...
Effects of Pregnancy and Lactation on Bone Microstructure and Material Properties in a Rat Model of Bariatric Surgery
Effects of Pregnancy and Lactation on Bone Microstructure and Material Properties in a Rat Model of Bariatric Surgery
Obesity is a major public health issue worldwide. Despite various approaches to weight loss, the most effective technique ...
Serum Pentosidine in Relation to Obesity in Patients with Type 2 Diabetes and Healthy Controls
Serum Pentosidine in Relation to Obesity in Patients with Type 2 Diabetes and Healthy Controls
Pentosidine (PEN), a surrogate marker of advanced glycation end-product formation, reflects increased non-enzymatic cross-...
Adipose-Derived Stromal Cell Conditioned Medium on Bone Remodeling: Insights from a 3D Osteoblast–Osteoclast Co-Culture Model
Adipose-Derived Stromal Cell Conditioned Medium on Bone Remodeling: Insights from a 3D Osteoblast–Osteoclast Co-Culture Model
This study describes the potential of the conditioned medium (CM) from adipose-derived mesenchymal stromal cells (ASCs) to...
Effect of Eight Months of Swimming on Bone Quality of Different Anatomical Regions: A Study on Wistar Rat Models
Effect of Eight Months of Swimming on Bone Quality of Different Anatomical Regions: A Study on Wistar Rat Models
Swimming is a popular sport with several health benefits, but its effects on bone quality are controversial possibly due t...
Tibial Skeletal Adaptations in Male and Female Marine Corps Officer Candidates Undergoing 10 Weeks of Military Training
Tibial Skeletal Adaptations in Male and Female Marine Corps Officer Candidates Undergoing 10 Weeks of Military Training
Military training improves tibial density, structure, and estimated strength; however, men and women may adapt differently...
The Multifactorial Relationship Between Bone Tissue Water and Stiffness at the Proximal Femur
The Multifactorial Relationship Between Bone Tissue Water and Stiffness at the Proximal Femur
Bone mechanical function is determined by multiple factors, some of which are still being elucidated. Here, we present a m...
18F-Sodium Fluoride PET/CT as a Tool to Assess Enthesopathies in X-Linked Hypophosphatemia
18F-Sodium Fluoride PET/CT as a Tool to Assess Enthesopathies in X-Linked Hypophosphatemia
X-linked hypophosphatemia (XLH) is a rare metabolic disorder characterized by elevated FGF23 and chronic hypophosphatemia,...
Unusual Association of Partial Fanconi Syndrome and Tumor-Induced Osteomalacia Revealed by Multiple Vertebral Fractures
Unusual Association of Partial Fanconi Syndrome and Tumor-Induced Osteomalacia Revealed by Multiple Vertebral Fractures
Tumor-induced osteomalacia (TIO) is a rare acquired paraneoplastic syndrome caused by a mesenchymal tumor secreting a phos...
Zebrafish Models for Skeletal and Extraskeletal Osteogenesis Imperfecta Features: Unveiling Pathophysiology and Paving the Way for Drug Discovery
Zebrafish Models for Skeletal and Extraskeletal Osteogenesis Imperfecta Features: Unveiling Pathophysiology and Paving the Way for Drug Discovery
In the last decades, the easy genetic manipulation, the external fertilization, the high percentage of homology with human...
Effect of Fibroblast Growth Factor (FGF) 19 and 21 on Hip Geometry and Strength in Post-menopausal Osteoporosis (PMO)
Effect of Fibroblast Growth Factor (FGF) 19 and 21 on Hip Geometry and Strength in Post-menopausal Osteoporosis (PMO)
Fibroblast Growth Factor (FGF) receptor signalling is important for skeletal development. The FGF19 subfamily which includ...
Causes of Musculoskeletal Pain in Paget’s Disease of Bone
Causes of Musculoskeletal Pain in Paget’s Disease of Bone
Paget’s disease of bone (PDB) is characterised by increased and disorganised bone remodelling leading to various com...
Influence of Menstrual Cycle and Oral Contraceptive Phases on Bone (re)modelling Markers in Response to Interval Running
Influence of Menstrual Cycle and Oral Contraceptive Phases on Bone (re)modelling Markers in Response to Interval Running
To explore how sex hormone fluctuations may affect bone metabolism, this study aimed to examine P1NP and β-CTX-1 conc...
Evaluation of the Nordic Musculoskeletal Questionnaire for Measuring Prevalence and the Consequence of Pain in a Danish Adult OI Population: A Pilot Study
Evaluation of the Nordic Musculoskeletal Questionnaire for Measuring Prevalence and the Consequence of Pain in a Danish Adult OI Population: A Pilot Study
Pain is a challenge in persons with OI and causes much concern in the Osteogenesis Imperfecta (OI) population. We aim to e...
Association Between Dietary Acid Load and Grip Strength in Adults 50 Years and Older: A Cross-Sectional Study
Association Between Dietary Acid Load and Grip Strength in Adults 50 Years and Older: A Cross-Sectional Study
Minimal data exist on whether the acid–base balance of the diet is linked to muscle strength. The aim of th...
The Characteristics of Gut Microbiota and Its Relation with Diet in Postmenopausal Osteoporosis
The Characteristics of Gut Microbiota and Its Relation with Diet in Postmenopausal Osteoporosis
The gut microbiome is linked to osteoporosis. Previous clinical studies showed inconsistent results. This study aimed to c...
Evaluation of Potential Roles of Zinc Finger Homeobox 3 (Zfhx3) Expressed in Chondrocytes and Osteoblasts on Skeletal Growth in Mice
Evaluation of Potential Roles of Zinc Finger Homeobox 3 (Zfhx3) Expressed in Chondrocytes and Osteoblasts on Skeletal Growth in Mice
Bone formation is tightly modulated by genetically encoded molecular proteins that interact to regulate cellular different...
Developing Cut-off Values for Low and Very Low Bone Mineral Density at the Thoracic Spine Using Quantitative Computed Tomography
Developing Cut-off Values for Low and Very Low Bone Mineral Density at the Thoracic Spine Using Quantitative Computed Tomography
Osteoporosis is under-diagnosed while detectable by measuring bone mineral density (BMD) using quantitative computer tomog...
The Relationship between Sclerostin and Kidney Transplantation Mineral Bone Disorders: A Molecule of Controversies
The Relationship between Sclerostin and Kidney Transplantation Mineral Bone Disorders: A Molecule of Controversies
Kidney transplantation is the most effective treatment option for most patients with end-stage kidney disease due to reduc...
Muscle Performance as a Predictor of Bone Health: Among Community-Dwelling Postmenopausal Japanese Women from Setagaya-Aoba Study
Muscle Performance as a Predictor of Bone Health: Among Community-Dwelling Postmenopausal Japanese Women from Setagaya-Aoba Study
Osteoporosis is a significant health concern for postmenopausal women, necessitating efficient screening methods for bone ...
Exogenous Angiotensin-(1–7) Provides Protection Against Inflammatory Bone Resorption and Osteoclastogenesis by Inhibition of TNF-α Expression in Macrophages
Exogenous Angiotensin-(1–7) Provides Protection Against Inflammatory Bone Resorption and Osteoclastogenesis by Inhibition of TNF-α Expression in Macrophages
Renin–angiotensin–aldosterone system plays a crucial role in the regulation of blood pressure and fluid homeos...
3D U-Net Neural Network Architecture-Assisted LDCT to Acquire Vertebral Morphology Parameters: A Vertebral Morphology Comprehensive Analysis in a Chinese Population
3D U-Net Neural Network Architecture-Assisted LDCT to Acquire Vertebral Morphology Parameters: A Vertebral Morphology Comprehensive Analysis in a Chinese Population
To evaluate the feasibility of acquiring vertebral height from chest low-dose computed tomography (LDCT) images using an a...
Short-Term Changes in Bone Metabolism Among Transgender Men Starting Gender-Affirming Hormone Therapy: A Systematic Review and Meta-analysis
Short-Term Changes in Bone Metabolism Among Transgender Men Starting Gender-Affirming Hormone Therapy: A Systematic Review and Meta-analysis
Transgender and gender diverse individuals experience a gender identity that differs from the sex assigned at birth. Some ...
Long-Term Follow-up After Ovariectomy Reveals Correlations Between Bone Marrow Adiposity and Trabecular Bone Quality in the Proximal Metaphysis of Tibiae in Rats
Long-Term Follow-up After Ovariectomy Reveals Correlations Between Bone Marrow Adiposity and Trabecular Bone Quality in the Proximal Metaphysis of Tibiae in Rats
This study aimed to evaluate the correlation between BMAT and bone quality, describe the long-term effects of ovariectomy ...
Sex-Specific Association Patterns of Bone Microstructure and Lower Leg Arterial Calcification
Sex-Specific Association Patterns of Bone Microstructure and Lower Leg Arterial Calcification
In conversations about bone loss and the importance of calcium homeostasis, patients frequently inquire about the associat...
Enzymatic and Non-enzymatic Collagen Cross-Links and Fracture Occurrence in Type 1 Diabetes Patients
Enzymatic and Non-enzymatic Collagen Cross-Links and Fracture Occurrence in Type 1 Diabetes Patients
Increased fracture risk in type 1 diabetes (T1D) patients is not fully captured by bone mineral density (BMD) by DXA. Adva...
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