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SCI Abstract
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ALL
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Value-Based Healthcare in Practice: IDEATE, a Collaboration to Design and Test an Outcomes-Based Agreement for a Medicine in Wales
To develop a sustainable, scalable methodology for the design of outcome-based agreements (OBAs) that works on the ground ...
Pharmacoeconomics
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Recurrence of Cardiovascular Events After an Acute Myocardial Infarction in Patients with Multivessel Disease and Associated Healthcare Costs: A German Claims Data Analysis
This study sought to quantify the healthcare costs of multivessel disease (MVD) and determine the prevalence and incidence...
Pharmacoeconomics
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EQ-5D-5L or EQ-HWB-S: Which is the Better Instrument for Capturing Spillover Effects in Parental Carers of Children with COVID-19?
‘Caregiver health spillovers’ refer to the broader impacts of an individual’s illness and interventions ...
Pharmacoeconomics
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Towards Recommendations for Cost-Effectiveness Analysis of Predictive, Prognostic, and Serial Biomarker Tests in Oncology
Cost-effectiveness analysis (CEA) of biomarkers is challenging due to the indirect impact on health outcomes and the lack ...
Pharmacoeconomics
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A Taxonomy for Assessing Whether HRQoL Value Sets Are Obsolete
Providing health-related quality of life (HRQoL) value sets to enable estimation of quality adjusted life years (QALYs) is...
Pharmacoeconomics
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Cost-Effectiveness Analysis of Nirsevimab for Preventing Respiratory Syncytial Virus-Related Lower Respiratory Tract Disease in Dutch Infants: An Analysis Including All-Infant Protection
This study aimed to assess the cost effectiveness of nirsevimab, a recently authorized monoclonal antibody (mAb) for the p...
Pharmacoeconomics
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Innovative Payment Models for Sickle-Cell Disease Gene Therapies in Medicaid: Leveraging Real-World Data and Insights from CMMI’s Gene Therapy Access Model
This study aims to evaluate the financial implications of implementing various payment models, including outcome-based agr...
Pharmacoeconomics
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Making Composite Time Trade-Off Sensitive for Worse-than-Dead Health States
The utilities elicited with the composite time trade-off (cTTO) method for health states worse-than-dead (WTD) often corre...
Pharmacoeconomics
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Immediate Versus 5-Year Risk-Guided Initiation of Treatment for Primary Prevention of Cardiovascular Disease for Australians Aged 40 Years: A Health Economic Analysis
Current Australian cardiovascular disease (CVD) prevention guidelines calculate 5-year CVD risk and recommend treatment wh...
Pharmacoeconomics
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A Multistate Model Incorporating Relative Survival Extrapolation and Mixed Time Scales for Health Technology Assessment
Multistate models have been widely applied in health technology assessment. However, extrapolating survival in a multistat...
Pharmacoeconomics
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Economic Evaluations of Non-Pharmacological Interventions for Treating Disorders of Gut-Brain Interaction: A Scoping Review
Disorders of gut-brain interaction are highly prevalent and burdensome conditions for both patients and healthcare systems...
Pharmacoeconomics
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Cost Effectiveness of Tremelimumab Plus Durvalumab for Unresectable Hepatocellular Carcinoma in the USA
Treating unresectable hepatocellular carcinoma (uHCC) is challenging. Clinical trials have shown that Single Tremelimumab ...
Pharmacoeconomics
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Application of Multi-level Network Meta-Regression in the NICE Technology Appraisal of Quizartinib for Induction, Consolidation and Maintenance Treatment of Newly Diagnosed FLT3-ITD-Positive Acute Myeloid Leukaemia: An External Assessment Group Perspective
NICE invited Daiichi Sankyo UK to submit evidence for the clinical and cost effectiveness of quizartinib (Vanflyta®) for t...
Pharmacoeconomics
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Public Health Impact of Introducing a Pentavalent Vaccine Against Invasive Meningococcal Disease in the United States
Invasive meningococcal disease (IMD) is primarily associated with five Neisseria meningitidis serogroups: A, B, C, W, or Y...
Pharmacoeconomics
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Cost-Effectiveness of Capivasertib as a Second-Line Therapy for Advanced Breast Cancer
Capivasertib, a first-in-class AKT inhibitor, was recently approved as a second-line treatment for advanced breast cancer....
Pharmacoeconomics
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Unravelling the Association Between Uncertainties in Model-based Economic Analysis and Funding Recommendations of Medicines in Australia
Health technology assessment is used extensively by the Pharmaceutical Benefits Advisory Committee (PBAC) to inform medici...
Pharmacoeconomics
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How Much Better is Faster? Empirical Tests of QALY Assumptions in Health-Outcome Sequences
This study was designed to test hypotheses regarding the path dependence of health-outcome values in the form of linear ad...
Pharmacoeconomics
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Managed Entry Agreements for High-Cost, One-Off Potentially Curative Therapies: A Framework and Calculation Tool to Determine Their Suitability
To construct a framework and calculation tool to compare the consequences of implementing different payment models for hig...
Pharmacoeconomics
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The Impact of Tocilizumab Coverage on Health Equity for Inpatients with COVID-19 in the USA: A Distributional Cost-Effectiveness Analysis
We conducted a distributional cost-effectiveness analysis to evaluate how coverage of tocilizumab for inpatients with COVI...
Pharmacoeconomics
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Economic Burden Associated with Pulmonary Arterial Hypertension in the United States
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by elevated pressure in the pulmonary arterie...
Pharmacoeconomics
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Universal Health Coverage of Opioid Agonist Treatment in Norway: An Equity-Adjusted Economic Evaluation
Detailed information on the efficiency of health services targeting opioid use disorder (OUD) and treatment with opioid ag...
Pharmacoeconomics
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Estimating the Incremental Cost Per QALY Produced by the Spanish NHS: A Fixed-Effect Econometric Approach
Knowing the health opportunity costs of funding decisions is crucial to assess whether the health gains associated with ne...
Pharmacoeconomics
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Treatment Effect Waning in Immuno-oncology Health Technology Assessments: A Review of Assumptions and Supporting Evidence with Proposals to Guide Modelling
Treatment effect waning (TEW) refers to the attenuation of treatment effects over time. Assumptions of a sustained immuno-...
Pharmacoeconomics
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Improving Transparency of Decision Models Through the Application of Decision Analytic Models with Omitted Objects Displayed (DAMWOOD)
The coronavirus disease 2019 (COVID-19) pandemic has increased public awareness of the influence of epidemiological and ec...
Pharmacoeconomics
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Barriers and Facilitators of Using R for Decision Analytic Modeling in Health Technology Assessment: Focus Group Results
Decision models for health technology assessment (HTA) are largely submitted to HTA agencies using commercial software, wh...
Pharmacoeconomics
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Cost-of-Illness of Skin Cancer: A Systematic Review
Skin cancer’s rising incidence demands understanding of its economic impact. The current understanding is fragmented...
Pharmacoeconomics
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Cost-Effectiveness of Plasma Microbial Cell-Free DNA Sequencing When Added to Usual Care Diagnostic Testing for Immunocompromised Host Pneumonia
Immunocompromised host pneumonia (ICHP) is an important cause of morbidity and mortality, yet usual care (UC) diagnostic t...
Pharmacoeconomics
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Estimating an EQ-5D-Y-3L Value Set for Brazil
The EQ-5D-Y-3L is a generic measure of health-related quality of life in children and adolescents. Although the Brazilian-...
Pharmacoeconomics
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Evaluating the Public Health and Health Economic Impacts of Baloxavir Marboxil and Oseltamivir for Influenza Pandemic Control in China: A Cost-Effectiveness Analysis Using a Linked Dynamic Transmission–Economic Evaluation Model
Pandemic influenza poses a recurring threat to public health. Antiviral drugs are vital in combating influenza pandemics. ...
Pharmacoeconomics
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Measuring the Direct Medical Costs of Hospital-Onset Infections Using an Analogy Costing Framework
The majority of recent estimates on the direct medical cost attributable to hospital-onset infections (HOIs) has focused o...
Pharmacoeconomics
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