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Pneumococci remain the main cause of complicated pediatric pneumonia in the post-pandemic era despite extensive pneumococcal vaccine use
Pneumococci remain the main cause of complicated pediatric pneumonia in the post-pandemic era despite extensive pneumococcal vaccine use
Nucleic acid amplification tests (NAATs) greatly enhance the capacity to identify the etiology of pediatric complicated pn...
Oxygenation indices and early prediction of outcome in hypoxemic patients with COVID-19 pneumonia requiring noninvasive respiratory support in pulmonary intermediate care unit
Oxygenation indices and early prediction of outcome in hypoxemic patients with COVID-19 pneumonia requiring noninvasive respiratory support in pulmonary intermediate care unit
Early prediction of non-invasive respiratory therapy (NIRT) failure is crucial to avoid needless prolongation of respirato...
Pre-vaccination carriage prevalence of Streptococcus pneumoniae serotypes among internally displaced people in Somaliland: a cross-sectional study
Pre-vaccination carriage prevalence of Streptococcus pneumoniae serotypes among internally displaced people in Somaliland: a cross-sectional study
Populations affected by humanitarian crises likely experience high burdens of pneumococcal disease. Streptococcus pneumoni...
Mortality reduction with 23-valent pneumococcal polysaccharide vaccine: a systematic review and meta-analysis
Mortality reduction with 23-valent pneumococcal polysaccharide vaccine: a systematic review and meta-analysis
Pneumococcal disease, caused by Streptococcus pneumoniae, imposes a significant global health burden, particularly affecti...
Can clinical findings at admission allow withholding of antibiotics in patients hospitalized for community acquired pneumonia when a test for a respiratory virus is positive?
Can clinical findings at admission allow withholding of antibiotics in patients hospitalized for community acquired pneumonia when a test for a respiratory virus is positive?
Current guidelines recommend empiric antibiotic therapy for patients who require hospitalization for community-acquired pn...
Relationships between human serum albumin levels and septic shock, in-hospital, and out-of-hospital mortality in elderly patients with pneumonia in different BMI ranges
Relationships between human serum albumin levels and septic shock, in-hospital, and out-of-hospital mortality in elderly patients with pneumonia in different BMI ranges
This retrospective cohort identified the association of human serum albumin (HSA) with adverse outcomes (septic shock, in-...
Radiographically confirmed pneumonia in Malawian children and associated pneumococcal carriage after introduction of the 13-valent pneumococcal conjugate vaccine
Radiographically confirmed pneumonia in Malawian children and associated pneumococcal carriage after introduction of the 13-valent pneumococcal conjugate vaccine
The 13-valent pneumococcal conjugate vaccine (PCV-13) was introduced in Malawi in 2011 with an expected impact of reducing...
Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae in China among children under 14 years of age post-implementation of the PCV13: a systematic review and meta-analysis (2017–2024)
Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae in China among children under 14 years of age post-implementation of the PCV13: a systematic review and meta-analysis (2017–2024)
Streptococcus pneumoniae (S. pneumoniae) is a major cause of morbidity and mortality in children worldwide, and its evolvi...
Pneumonic-type lung adenocarcinoma with KRAS G12V mutation and sustained response to Afatinib
Pneumonic-type lung adenocarcinoma with KRAS G12V mutation and sustained response to Afatinib
Pneumonic-type lung adenocarcinoma (P-ADC) is a rare and challenging subtype of primary lung cancer that can be difficult ...
Accuracy of the recording of pneumonia events in English electronic healthcare record data in patients with chronic obstructive pulmonary disease
Accuracy of the recording of pneumonia events in English electronic healthcare record data in patients with chronic obstructive pulmonary disease
In primary care, identifying pneumonia events in people with chronic obstructive pulmonary disease (COPD) may be challengi...
Invasive pulmonary aspergillosis among patients with severe community-acquired pneumonia and influenza in ICUs: a retrospective cohort study
Invasive pulmonary aspergillosis among patients with severe community-acquired pneumonia and influenza in ICUs: a retrospective cohort study
The prevalence, clinical characteristics, and outcomes of invasive pulmonary aspergillosis in patients with severe communi...
Back to the future: the novel art of digital auscultation applied in a prospective observational study of critically ill Covid-19 patients
Back to the future: the novel art of digital auscultation applied in a prospective observational study of critically ill Covid-19 patients
The Covid-19 pandemic has caused immense pressure on Intensive Care Units (ICU). In patients with severe ARDS due to Covid...
Obtaining patient phenotypes in SARS-CoV-2 pneumonia, and their association with clinical severity and mortality
Obtaining patient phenotypes in SARS-CoV-2 pneumonia, and their association with clinical severity and mortality
There exists consistent empirical evidence in the literature pointing out ample heterogeneity in terms of the clinical evo...
Serum soluble toll-like receptor 4 and risk for clinical severity in COVID-19 patients
Serum soluble toll-like receptor 4 and risk for clinical severity in COVID-19 patients
Toll-like receptor 4 (TLR4) signaling mediates sustained systemic inflammation in(COVID)-19 patients. We aimed to assess t...
Time to recovery and its determinant factors among patients with COVID-19 in Assosa COVID-19 treatment center, Western Ethiopia
Time to recovery and its determinant factors among patients with COVID-19 in Assosa COVID-19 treatment center, Western Ethiopia
The Novel Coronavirus disease (COVID-19) pandemic has become a global threat. Determining the time to recovery from COVID-...
A high α1-antitrypsin/interleukin-10 ratio predicts bacterial pneumonia in adults with community-acquired pneumonia: a prospective cohort study
A high α1-antitrypsin/interleukin-10 ratio predicts bacterial pneumonia in adults with community-acquired pneumonia: a prospective cohort study
Current microbiological tests fail to identify the causative microorganism in more than half of all pneumonia cases. We ex...
Risk of subsequent lower respiratory tract infection (LRTI) after hospitalization for COVID-19 LRTI and non-COVID-19 LRTI: a retrospective cohort study
Risk of subsequent lower respiratory tract infection (LRTI) after hospitalization for COVID-19 LRTI and non-COVID-19 LRTI: a retrospective cohort study
Respiratory pathogens, including SARS-CoV-2, can cause pulmonary structural damage and physiologic impairment, which may i...
Thymalfasin therapy accelerates COVID-19 pneumonia rehabilitation through anti-inflammatory mechanisms
Thymalfasin therapy accelerates COVID-19 pneumonia rehabilitation through anti-inflammatory mechanisms
Thymosin drugs are commonly used for the treatment of viral infections due to their immunomodulatory effects. The comprehe...
Risk of pneumonia in the vicinity of goat farms: a comparative assessment of temporal variation based on longitudinal health data
Risk of pneumonia in the vicinity of goat farms: a comparative assessment of temporal variation based on longitudinal health data
Although the association between living in the vicinity of a goat farm and the occurrence of pneumonia is well-documented,...
A brief history of and future prospects for pneumococcal vaccination in Malaysia
A brief history of and future prospects for pneumococcal vaccination in Malaysia
Pneumococcal pneumonia remains a significant global public health issue. Malaysia has recently added the 10 valent pneumoc...
Clinical algorithm reduces antibiotic use among children presenting with respiratory symptoms to hospital in central Vietnam
Clinical algorithm reduces antibiotic use among children presenting with respiratory symptoms to hospital in central Vietnam
To assess the safety and utility of a pragmatic clinical algorithm to guide rational antibiotic use in children presenting...
Effects of pneumococcal conjugate vaccines on reducing the risk of respiratory disease associated with coronavirus infection
Effects of pneumococcal conjugate vaccines on reducing the risk of respiratory disease associated with coronavirus infection
Pneumococcal conjugate vaccines (PCVs) provide protection against vaccine-type pneumococcal disease in both children and a...
Correction: Promoting the use of social networks in pneumonia
Correction: Promoting the use of social networks in pneumonia
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whic...
Incidence of non-invasive all-cause pneumonia in children in the United States before and after the introduction of pneumococcal conjugate vaccines: a retrospective claims database analysis
Incidence of non-invasive all-cause pneumonia in children in the United States before and after the introduction of pneumococcal conjugate vaccines: a retrospective claims database analysis
Pneumonia is the most serious form of acute respiratory infection and Streptococcus pneumoniae is a leading cause of pedia...
Healthcare resource utilization and cost of pneumococcal disease in children in Germany, 2014–2019: a retrospective cohort study
Healthcare resource utilization and cost of pneumococcal disease in children in Germany, 2014–2019: a retrospective cohort study
Since the introduction of higher valency pneumococcal conjugate vaccines in 2009, recent estimates on the economic burden ...
Innate immune responses in pneumonia
Innate immune responses in pneumonia
The lungs are an immunologically unique environment; they are exposed to innumerable pathogens and particulate matter dail...
Acute organ injury and long-term sequelae of severe pneumococcal infections
Acute organ injury and long-term sequelae of severe pneumococcal infections
Streptococcus pneumoniae (Spn) is a major public health problem, as it is a main cause of otitis media, community-acquired...
In memory of Allan William Cripps AO (1950–2022)
In memory of Allan William Cripps AO (1950–2022)
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whic...
Pulse oximetry: why oxygen saturation is still not a part of standard pediatric guidelines in low-and-middle-income countries (LMICs)
Pulse oximetry: why oxygen saturation is still not a part of standard pediatric guidelines in low-and-middle-income countries (LMICs)
With the high frequency of acute respiratory infections in children worldwide, particularly so in low-resource countries, ...
Incidence of pneumococcal disease from 2003 to 2019 in children ≤17 years in England
Incidence of pneumococcal disease from 2003 to 2019 in children ≤17 years in England
Pneumococcal disease is a leading cause of communicable disease morbidity and mortality globally. We aimed to estimate inv...
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