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3-Hydroxybutyrate, a metabolite in sustaining neuronal cell vitality: a mendelian randomization and in vitro experimentation
3-Hydroxybutyrate, a metabolite in sustaining neuronal cell vitality: a mendelian randomization and in vitro experimentation
Recent research has implicated mitochondrial DNA copy number (mtDNA-CN) and Tau protein levels in the blood as potential b...
Dietary antioxidants and mortality in early-stage CKM syndrome: insights from NHANES
Dietary antioxidants and mortality in early-stage CKM syndrome: insights from NHANES
Cardiovascular-kidney-metabolic (CKM) syndrome is a newly recognized multisystem disorder, with over 90% of cases occurrin...
Effects of skipping breakfast, lunch or dinner on subsequent postprandial blood glucose levels among healthy young adults
Effects of skipping breakfast, lunch or dinner on subsequent postprandial blood glucose levels among healthy young adults
Meal skipping has become increasingly common in modern society due to changes in lifestyle. While the adverse effects of s...
Multi-omics analyses the effect of Bifidobacterium longum subsp. longum BL21 supplementation on overweight and obese subjects: a randomized, double-blind, placebo-controlled study
Multi-omics analyses the effect of Bifidobacterium longum subsp. longum BL21 supplementation on overweight and obese subjects: a randomized, double-blind, placebo-controlled study
Bifidobacterium longum subsp. longum BL21 has demonstrated promise in alleviating gut microbiota disturbances and metaboli...
Omega-3 supplementation and cardiometabolic risk factors in obese/overweight children and adolescents: a GRADE assessed systematic review and meta-analysis
Omega-3 supplementation and cardiometabolic risk factors in obese/overweight children and adolescents: a GRADE assessed systematic review and meta-analysis
Omega-3 polyunsaturated fatty acids (ɷ3 PUFA), have been proposed as a supplement to improve cardiometabolic risk fac...
Aortic pulse wave velocity predicts cardiovascular mortality among middle-aged metabolic syndrome subjects without overt cardiovascular disease
Aortic pulse wave velocity predicts cardiovascular mortality among middle-aged metabolic syndrome subjects without overt cardiovascular disease
The objective of this cohort study was to assess the predictive value of main arterial markers for cardiovascular death in...
L-arginine mitigates cardiac lipid and glucose accumulation through leptin modulation and enhancement of PIK3 activities in high fat-fed male Wistar rats
L-arginine mitigates cardiac lipid and glucose accumulation through leptin modulation and enhancement of PIK3 activities in high fat-fed male Wistar rats
Insulin resistance and other metabolic risk factors are associated with increased cardiovascular diseases in animals fed w...
Association between modified dietary inflammation index score and lumbar vertebrae bone mineral density in patients with hypertension: data from NHANES—a population-based study
Association between modified dietary inflammation index score and lumbar vertebrae bone mineral density in patients with hypertension: data from NHANES—a population-based study
The modified Dietary Inflammation Index Score (M-DIS) is a scoring system used to quantify the inflammatory effects of nut...
The role of circulating polyunsaturated fatty acids in mediating the effect of BMI on leukocyte telomere length: analysis using Mendelian randomization
The role of circulating polyunsaturated fatty acids in mediating the effect of BMI on leukocyte telomere length: analysis using Mendelian randomization
polyunsaturated fatty acids (PUFAs) are a category of fatty acids that contain omega-3 and omega-6 fatty acids, which cons...
Impact of vitamins A, D, and homocysteine on cardiometabolic multimorbidity in Northwest China
Impact of vitamins A, D, and homocysteine on cardiometabolic multimorbidity in Northwest China
To investigate the impact of vitamin A (VA), vitamin D (VD), and homocysteine (Hcy) on cardiometabolic multimorbidity (CMM...
Free fatty acids and mortality among adults in the United States: a report from US National Health and Nutrition Examination Survey (NHANES)
Free fatty acids and mortality among adults in the United States: a report from US National Health and Nutrition Examination Survey (NHANES)
The relationship between free fatty acids (FFAs) and the risk of mortality remains unclear. There is a scarcity of prospec...
Turkish coffee has an antitumor effect on breast cancer cells in vitro and in vivo
Turkish coffee has an antitumor effect on breast cancer cells in vitro and in vivo
Breast cancer is the most diagnosed cancer in women. Its pathogenesis includes several pathways in cancer proliferation, a...
Amelioration of Atherosclerosis by lycopene is linked to the modulation of gut microbiota dysbiosis and related gut-heart axis activation in high-fat diet-fed ApoE−/− mice
Amelioration of Atherosclerosis by lycopene is linked to the modulation of gut microbiota dysbiosis and related gut-heart axis activation in high-fat diet-fed ApoE−/− mice
Interplay between gut microbiota and heart, termed “gut-heart” axis, has a crucial role in the pathogenesis of...
Correction: The association between dietary quality scores with C-reactive protein and novel biomarkers of inflammation platelet-activating factor and lipoprotein-associated phospholipase A2: a cross-sectional study
Correction: The association between dietary quality scores with C-reactive protein and novel biomarkers of inflammation platelet-activating factor and lipoprotein-associated phospholipase A2: a cross-sectional study
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Intrauterine growth restriction alters kidney metabolism at the end of nephrogenesis
Intrauterine growth restriction alters kidney metabolism at the end of nephrogenesis
This study investigated the effect of uteroplacental insufficiency (UPI) on renal development by detecting metabolic alter...
Exploring the underlying mechanisms of fisetin in the treatment of hepatic insulin resistance via network pharmacology and in vitro validation
Exploring the underlying mechanisms of fisetin in the treatment of hepatic insulin resistance via network pharmacology and in vitro validation
To characterize potential mechanisms of fisetin on hepatic insulin resistance (IR) using network pharmacology and in vitro...
A comparative study on indicators of vitamin A status and risk factors for sensitivity and specificity of the methods to detect vitamin A deficiency
A comparative study on indicators of vitamin A status and risk factors for sensitivity and specificity of the methods to detect vitamin A deficiency
Serum retinol (SR) and retinol-binding protein (RBP) are commonly used indicators, but they are affected by infections and...
The association of serum betaine concentrations with the risk of new-onset cancers: results from two independent nested case-control studies
The association of serum betaine concentrations with the risk of new-onset cancers: results from two independent nested case-control studies
Evidence from epidemiologic studies on the association of circulating betaine levels with the incident risk of cancer has ...
Early adulthood weight change, midlife “Life’s essential 8” health status and risk of cardiometabolic diseases: a chinese nationwide cohort study
Early adulthood weight change, midlife “Life’s essential 8” health status and risk of cardiometabolic diseases: a chinese nationwide cohort study
The association between weight change during early adulthood and cardiometabolic diseases remains uncertain in Chinese pop...
Healthy lifestyle scores associate with incidence of type 2 diabetes mediated by uric acid
Healthy lifestyle scores associate with incidence of type 2 diabetes mediated by uric acid
Whether and to what extent serum uric acid (SUA) mediates the association between combined lifestyle behaviors and type 2 ...
Does dietary nitrate boost the effects of caloric restriction on brain health? Potential physiological mechanisms and implications for future research
Does dietary nitrate boost the effects of caloric restriction on brain health? Potential physiological mechanisms and implications for future research
Dementia is a highly prevalent and costly disease characterised by deterioration of cognitive and physical capacity due to...
Differential effects of plant-based flours on metabolic homeostasis and the gut microbiota in high-fat fed rats
Differential effects of plant-based flours on metabolic homeostasis and the gut microbiota in high-fat fed rats
The gut microbiome is a salient contributor to the development of obesity, and diet is the greatest modifier of the gut mi...
The effect of the modified fat-protein unit algorithm compared with that of carbohydrate counting on postprandial glucose in adults with type-1 diabetes when consuming meals with differing macronutrient compositions: a randomized crossover trial
The effect of the modified fat-protein unit algorithm compared with that of carbohydrate counting on postprandial glucose in adults with type-1 diabetes when consuming meals with differing macronutrient compositions: a randomized crossover trial
The optimization of glucose control in type-1 diabetes is challenged by postprandial glycemic variability. This study aime...
New insights into the nutritional genomics of adult-onset riboflavin-responsive diseases
New insights into the nutritional genomics of adult-onset riboflavin-responsive diseases
Riboflavin, or vitamin B2, is an essential nutrient that serves as a precursor to flavin adenine dinucleotide (FAD) and fl...
Prospective association between an obesogenic dietary pattern in early adolescence and metabolomics derived and traditional cardiometabolic risk scores in adolescents and young adults from the ALSPAC cohort
Prospective association between an obesogenic dietary pattern in early adolescence and metabolomics derived and traditional cardiometabolic risk scores in adolescents and young adults from the ALSPAC cohort
Dietary intake during early life may be a modifying factor for cardiometabolic risk (CMR). Metabolomic profiling may enabl...
METTL3 exacerbates insulin resistance in hepatocytes by regulating m6A modification of cytochrome P450 2B6
METTL3 exacerbates insulin resistance in hepatocytes by regulating m6A modification of cytochrome P450 2B6
Insulin resistance (IR) in hepatocytes endangers human health, and frequently results in the development of non-alcoholic ...
Effect of weight change on the association between overall and source of carbohydrate intake and risk of metabolic syndrome: Tehran lipid and glucose study
Effect of weight change on the association between overall and source of carbohydrate intake and risk of metabolic syndrome: Tehran lipid and glucose study
In this prospective cohort study, we aimed to evaluate the association between dietary carbohydrates, whole grains, refine...
The association between dietary quality scores with C-reactive protein and novel biomarkers of inflammation platelet-activating factor and lipoprotein-associated phospholipase A2: a cross-sectional study
The association between dietary quality scores with C-reactive protein and novel biomarkers of inflammation platelet-activating factor and lipoprotein-associated phospholipase A2: a cross-sectional study
Healthy dietary patterns are associated with lower inflammation and cardiovascular disease (CVD) risk and adherence can be...
The impact of macrosomia on cardiometabolic health in preteens: findings from the ROLO longitudinal birth cohort study
The impact of macrosomia on cardiometabolic health in preteens: findings from the ROLO longitudinal birth cohort study
Macrosomia (birthweight ≥ 4 kg or ≥ 4.5 kg) is strongly associated w...
The effect of conjugated linoleic acids on inflammation, oxidative stress, body composition and physical performance: a comprehensive review of putative molecular mechanisms
The effect of conjugated linoleic acids on inflammation, oxidative stress, body composition and physical performance: a comprehensive review of putative molecular mechanisms
Conjugated linoleic acids (CLAs) are polyunsaturated fatty acids primarily found in dairy products and ruminant animal pro...
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