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Methylation of T and B Lymphocytes in Autoimmune Rheumatic Diseases
Methylation of T and B Lymphocytes in Autoimmune Rheumatic Diseases
The role of abnormal epigenetic modifications, particularly DNA methylation, in the pathogenesis of autoimmune rheumatic d...
Single-Cell Sequencing: High-Resolution Analysis of Cellular Heterogeneity in Autoimmune Diseases
Single-Cell Sequencing: High-Resolution Analysis of Cellular Heterogeneity in Autoimmune Diseases
Autoimmune diseases (AIDs) are complex in etiology and diverse in classification but clinically show similar symptoms such...
Atopic Dermatitis and Psoriasis: Similarities and Differences in Metabolism and Microbiome
Atopic Dermatitis and Psoriasis: Similarities and Differences in Metabolism and Microbiome
Atopic dermatitis and psoriasis are common chronic inflammatory diseases of high incidence that share some clinical featur...
Allergen Testing: A Review of the Indications, Procedures, and Limitations in Ocular Allergy
Allergen Testing: A Review of the Indications, Procedures, and Limitations in Ocular Allergy
Allergen-based diagnostics are essential in the management algorithm of allergic diseases. Unlike systemic allergy, where ...
Neutrophils in Atopic Dermatitis
Neutrophils in Atopic Dermatitis
Neutrophils have a critical role in inflammation. Recent studies have identified their distinctive presence in certain typ...
Efficacy of Capsaicin for Non-allergic Rhinitis: An Updated Systematic Review and Meta-analysis
Efficacy of Capsaicin for Non-allergic Rhinitis: An Updated Systematic Review and Meta-analysis
Non-allergic rhinitis (NAR) is a prevalent condition with limited effective treatments. Capsaicin, an agonist of the trans...
MDA5 Is a Major Determinant of Developing Symptoms in Critically Ill COVID-19 Patients
MDA5 Is a Major Determinant of Developing Symptoms in Critically Ill COVID-19 Patients
Apart from the skin and mucosal immune barrier, the first line of defense of the human immune system includes MDA5 (ifih1 ...
A Novel Subset of Regulatory T Cells Induced by B Cells Alleviate the Severity of Immunological Diseases
A Novel Subset of Regulatory T Cells Induced by B Cells Alleviate the Severity of Immunological Diseases
Regulatory T (Treg) cells are crucial for maintaining immune tolerance by suppressing response to self-antigens and harmle...
Hereditary Angioedema Attacks in Patients Receiving Long-Term Prophylaxis: A Systematic Review
Hereditary Angioedema Attacks in Patients Receiving Long-Term Prophylaxis: A Systematic Review
Long-term prophylaxis (LTP) has been shown to reduce the frequency of hereditary angioedema (HAE) attacks; however, attack...
Acute Aseptic Meningitis Temporally Associated with Intravenous Polyclonal Immunoglobulin Therapy: A Systematic Review
Acute Aseptic Meningitis Temporally Associated with Intravenous Polyclonal Immunoglobulin Therapy: A Systematic Review
An acute aseptic meningitis has been occasionally observed on intravenous polyclonal human immunoglobulin therapy. Since c...
The Immunology of Psoriasis—Current Concepts in Pathogenesis
The Immunology of Psoriasis—Current Concepts in Pathogenesis
Psoriasis is one of the most common inflammatory skin diseases with a chronic, relapsing-remitting course. The last decade...
Shrimp Extract Exacerbates Allergic Immune Responses in Mice: Implications on Clinical Diagnosis of Shellfish Allergy
Shrimp Extract Exacerbates Allergic Immune Responses in Mice: Implications on Clinical Diagnosis of Shellfish Allergy
Tropomyosin has been identified as the major cross-reactive shellfish allergen, but recent studies showed the presence of ...
From Skin to Solution: Exploring Epicutaneous Immunotherapy for Peanut Allergy—A Systematic Review and Meta-Analysis
From Skin to Solution: Exploring Epicutaneous Immunotherapy for Peanut Allergy—A Systematic Review and Meta-Analysis
Peanut allergy is a leading cause of severe food reactions. This meta-analysis evaluates the efficacy and safety of epicut...
Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis
Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis
Osteoporosis is a major clinical problem in many autoimmune diseases, including primary biliary cholangitis (PBC), the mos...
Down Syndrome and Autoimmune Disease
Down Syndrome and Autoimmune Disease
Down syndrome is the most common genetic cause of intellectual disability and has previously been associated with a variet...
Fibroblast: A Novel Target for Autoimmune and Inflammatory Skin Diseases Therapeutics
Fibroblast: A Novel Target for Autoimmune and Inflammatory Skin Diseases Therapeutics
Fibroblasts are crucial components of the skin structure. They were traditionally believed to maintain the skin’s st...
CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy
CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy
NKT cells, unique lymphocytes bridging innate and adaptive immunity, offer significant potential for managing inflammatory...
Fungal Head and Neck Dermatitis: Current Understanding and Management
Fungal Head and Neck Dermatitis: Current Understanding and Management
Head and neck dermatitis (HND) is a form of atopic dermatitis (AD) that affects the seborrheic areas of the body and cause...
Tumor Necrosis Factor Alpha Inhibitors and Cardiovascular Risk in Rheumatoid Arthritis
Tumor Necrosis Factor Alpha Inhibitors and Cardiovascular Risk in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by an increased risk of cardiovascular events, d...
Diverse Endotypes of Chronic Rhinosinusitis and Clinical Implications
Diverse Endotypes of Chronic Rhinosinusitis and Clinical Implications
Chronic rhinosinusitis (CRS) is a highly heterogeneous disease characterized by inflammation in the nasal and sinus mucosa...
Cellular and Molecular Mechanisms of Mast Cells in Atherosclerotic Plaque Progression and Destabilization
Cellular and Molecular Mechanisms of Mast Cells in Atherosclerotic Plaque Progression and Destabilization
Mast cells (MCs) are commonly recognized for their crucial involvement in the pathogenesis of allergic diseases, but over ...
B-Cell Receptor Repertoire: Recent Advances in Autoimmune Diseases
B-Cell Receptor Repertoire: Recent Advances in Autoimmune Diseases
In the field of contemporary medicine, autoimmune diseases (AIDs) are a prevalent and debilitating group of illnesses. How...
Is Food-Triggered Atopic Dermatitis a Form of Systemic Contact Dermatitis?
Is Food-Triggered Atopic Dermatitis a Form of Systemic Contact Dermatitis?
Food allergy in atopic dermatitis is mediated by complex immune interactions between genetics, diet, environment, and the ...
Tissue-Resident Memory T Cells in Allergy
Tissue-Resident Memory T Cells in Allergy
Tissue-resident memory T (TRM) cells constitute a distinct subset within the memory T cell population, serving as the vang...