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Should We Consider Water and Antibiotics to Be Geroprotectors?
Should We Consider Water and Antibiotics to Be Geroprotectors?
The authors try to consider the current situation with experimental gerontological research aimed at finding means to slow...
Larval Heat Stress Affects the Lifespan and Stress Resistance of Drosophila melanogaster Adults
Larval Heat Stress Affects the Lifespan and Stress Resistance of Drosophila melanogaster Adults
In modern conditions of constant adverse effects on living organisms, such as environmental pollution or global climate ch...
Role of BKCa Channels in Pial-Vessel Dilation in Rats of Different Ages
Role of BKCa Channels in Pial-Vessel Dilation in Rats of Different Ages
Studying the mechanisms of age-related changes in vascular reactions and applying the acquired knowledge in clinics can he...
On the Concentration of Vitamins A and E in the Tissues of the Bank Vole (Myodes (Clethrionomys) glareolus) and Common Shrew (Sorex araneus) Inhabiting Karelia
On the Concentration of Vitamins A and E in the Tissues of the Bank Vole (Myodes (Clethrionomys) glareolus) and Common Shrew (Sorex araneus) Inhabiting Karelia
We have studied the concentration of vitamins A (retinol) and E (α-tocopherol) in the tissues of the bank vole (Myode...
Comparative Analysis of Cell Senescence Induced by the Chemotherapeutic Agents Doxorubicin, Cisplatin and Arsenic Trioxide in Human Myoblasts MB135
Comparative Analysis of Cell Senescence Induced by the Chemotherapeutic Agents Doxorubicin, Cisplatin and Arsenic Trioxide in Human Myoblasts MB135
Genotoxic and cytotoxic drugs, widely used in anticancer therapy, target proliferating cells and induce cell death through...
Association between Telomere Length and Geriatric Status in Centenarians
Association between Telomere Length and Geriatric Status in Centenarians
Aim: To evaluate the association between telomere length and frailty and individual geriatric syndromes in older adults. M...
Geroprotective Effect of the Mitochondrial-Targeted Antioxidant SkQBerb in a Model of the Chronological Aging of MB135 Human Myoblasts
Geroprotective Effect of the Mitochondrial-Targeted Antioxidant SkQBerb in a Model of the Chronological Aging of MB135 Human Myoblasts
Background: The field of gerontology is actively seeking senolytics and senomorphs that can influence the quantity and act...
Senolytic Drugs: Implications for Clinical Practice
Senolytic Drugs: Implications for Clinical Practice
Studying the mechanisms of aging is one of the most important goals of modern science. A significant amount of data on the...
Brain Aging
Brain Aging
Brain aging is part of the aging of the whole body, largely determining the success of general aging and the quality of li...
Patterns of Expression of the Key Genes of the BDNF System and Serotonin Receptors in the Brain of OXYS Rats in the Development of the Signs of Alzheimer’s Disease
Patterns of Expression of the Key Genes of the BDNF System and Serotonin Receptors in the Brain of OXYS Rats in the Development of the Signs of Alzheimer’s Disease
In spite of numerous studies, pathogenesis of the sporadic (not inherited) form of Alzheimer’s disease (AD) still re...
The Role of the Serotonin Pathway of Tryptophan Metabolism in the Development of Neuroinflammation in Alzheimer’s Disease
The Role of the Serotonin Pathway of Tryptophan Metabolism in the Development of Neuroinflammation in Alzheimer’s Disease
Despite the fact that more than 90% of tryptophan is metabolized via the kynurenine pathway, the serotonin pathway is of g...
Age-Related Changes and Loss of Damage Resistance of Kidney Tissue: The Role of a Decrease in the Number of Kidney Resident Progenitor Cells
Age-Related Changes and Loss of Damage Resistance of Kidney Tissue: The Role of a Decrease in the Number of Kidney Resident Progenitor Cells
Many organs undergo negative changes during aging that affect their functions and ability to regenerate. In particular, th...
Demographic Indicators of Probability Models
Demographic Indicators of Probability Models
Describing mortality dynamics using average indicators without considering variability can yield average results, impeding...
Mechanisms of Neurocognitive Adaptation during Aging Process
Mechanisms of Neurocognitive Adaptation during Aging Process
Human aging is associated with an increased risk of various geriatric syndromes, cognitive impairment being among the most...
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