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American Society of Hematology (ASH) update 2023—chronic lymphocytic leukemia
American Society of Hematology (ASH) update 2023—chronic lymphocytic leukemia
In recent years, there has been massive advances in the treatment of chronic lymphocytic leukemia (CLL) from chemoimmunoth...
Unclassifiable acute leukemia with blastic plasmacytoid dendritic cell neoplasm: deciding on the appropriate therapy
Unclassifiable acute leukemia with blastic plasmacytoid dendritic cell neoplasm: deciding on the appropriate therapy
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, clinically aggressive tumor derived from the precursors of...
Implantable catheter chambers: a 14-year descriptive study
Implantable catheter chambers: a 14-year descriptive study
Implantable catheter chambers are widely used devices during the treatment of cancer whether for taking blood samples or f...
State-of-the-art therapy and innovative treatment strategies in esophageal squamous cell cancer
State-of-the-art therapy and innovative treatment strategies in esophageal squamous cell cancer
Recent advances in the development of new therapeutic agents and the execution of numerous randomized controlled trials ha...
Impact of the WHO-5 classification of haematolymphoid tumours on clinical practice
Impact of the WHO-5 classification of haematolymphoid tumours on clinical practice
The long-awaited 2022 World Health Organization Classification of Haematolymphoid Tumours (WHO-5-HAEM) has finally been pu...
Pulmonary puzzles: salivary gland-type tumors of the lung and their metastatic equivalents
Pulmonary puzzles: salivary gland-type tumors of the lung and their metastatic equivalents
In the last decade, the understanding of lung neoplasms, particularly rare salivary gland-type tumors (SGT), has deepened ...
Liquid profiling for patients with advanced cancer is ready for clinical integration
Liquid profiling for patients with advanced cancer is ready for clinical integration
Molecular profiling of circulating tumor DNA (ctDNA) to guide treatment decisions has found its way into routine managemen...
GATA2 deficiency: a mystery myelodysplasia
GATA2 deficiency: a mystery myelodysplasia
GATA2 deficiency, arising from mutations in the GATA2 gene, is a rare genetic disorder with profound implications...
Novel mutated Dubin–Johnson syndrome diagnosed during acute promyelocytic leukemia treatment
Novel mutated Dubin–Johnson syndrome diagnosed during acute promyelocytic leukemia treatment
Coexistence of acute promyelocytic leukemia and Dubin–Johnson syndrome (DJS) has not been previously reported in the...
Importance of allogeneic stem cell transplantation in myelofibrosis
Importance of allogeneic stem cell transplantation in myelofibrosis
Allogeneic stem cell transplantation (alloSCT) is the only curative treatment option for patients with high-risk myelofibr...
KRAS (Kirsten rat sarcoma) in modern oncology—The molecular pathological point of view
KRAS (Kirsten rat sarcoma) in modern oncology—The molecular pathological point of view
The Rat sarcoma protein (RAS) was the first proto-oncogene to be discovered and is one of the best researched tumor driver...
ASCO 2023: highlights in breast cancer
ASCO 2023: highlights in breast cancer
The 2023 annual meeting of the American Society of Clinical Oncology (ASCO) was again held in June 2023 in Chicag...
Cancer of unknown primary—state of the art
Cancer of unknown primary—state of the art
The Cancer of Unknown Primary (CUP) syndrome does not represent a single clinical entity but comprises a diverse group of ...
Emerging treatment strategies in chronic B-cell malignancies—News from ICML 2023
Emerging treatment strategies in chronic B-cell malignancies—News from ICML 2023
Implementation of targeted drugs in the treatment landscape of indolent B‑cell malignancies has facilitated long-ter...
Supportive management
Supportive management
The introduction of checkpoint inhibitor therapy and advances in targeted therapy...
Prostate cancer special—part 1
Prostate cancer special—part 1
Conflict of interest S.F. Shariat declares the following competing interes...
HER2 in focus—gastric cancer
HER2 in focus—gastric cancer
Conflict of interest A. Ilhan-Mutlu: Participation in advisory boards orga...
WNT3 and LEF1 as markers for diagnosis and survival prediction in chronic lymphocytic leukemia patients
WNT3 and LEF1 as markers for diagnosis and survival prediction in chronic lymphocytic leukemia patients
The Wnt pathway is aberrantly activated in chronic lymphocytic leukemia (CLL) and contributes to the antiapoptotic and mit...
Genetic testing and management of prostate cancer patients with pathogenic germline variants
Genetic testing and management of prostate cancer patients with pathogenic germline variants
Prostate cancer (PCa) is an androgen-receptor signaling-dependent disease with a subset of patients harboring pat...
Management of malignant hypercalcemia in cancer patients—a short review
Management of malignant hypercalcemia in cancer patients—a short review
Hypercalcemia of malignancy (HCM) can be the first symptom leading to diagnosis and initiation of treatment in cancer pati...
Renal cell carcinoma
Renal cell carcinoma
Kidney cancer accounts for 5% and 3% of all adult malignancies in men and women. Renal cell carcinoma (RCC) accounts for a...
Focal therapy in intermediate- and high-risk prostate cancer
Focal therapy in intermediate- and high-risk prostate cancer
Focal therapy is a treatment option for clinically localized prostate cancer, finding increased use in recent yea...
Essential news from ASCO 2023 in primary resectable and advanced or metastatic pancreatic cancer
Essential news from ASCO 2023 in primary resectable and advanced or metastatic pancreatic cancer
In this short review, we aim to summarize the essential news and highlights in pancreatic cancer that were presented at AS...
Imaging and therapy targeting PSMA receptors for enhanced vision and precise treatment
Imaging and therapy targeting PSMA receptors for enhanced vision and precise treatment
In Europe, it is estimated that more than 65,000 men die each year from the consequences of advanced and metastatic prosta...
Fifth-line HER2-directed therapy for metastatic adenocarcinoma of the gastroesophageal junction
Fifth-line HER2-directed therapy for metastatic adenocarcinoma of the gastroesophageal junction
Evaluation of HER2 status and programmed death-ligand 1 (PD-L1) combined positive score (CPS) is mandatory in all...