SCI Abstract

search
+
Real-world application of comprehensive genomic profiling for gynecological malignancies: a multicenter observational study
Real-world application of comprehensive genomic profiling for gynecological malignancies: a multicenter observational study
The actual status of comprehensive genomic profiling (CGP) applications in Japan has not been clarified. We conducted a mu...
Lateral node metastasis in low rectal cancer as a hallmark to predict recurrence patterns
Lateral node metastasis in low rectal cancer as a hallmark to predict recurrence patterns
Lateral node metastasis confers a poor prognosis in rectal cancer. Several multidisciplinary treatments have been proposed...
Effects of aging on complications following robot-assisted radical prostatectomy
Effects of aging on complications following robot-assisted radical prostatectomy
For prostate cancer (PCa) in the elderly, including patients ≥ 80 years, the safety of robot-as...
Discovery and validation of Hsa-microRNA-3665 promoter methylation as a potential biomarker for the prognosis of esophageal squaous cell carcinoma
Discovery and validation of Hsa-microRNA-3665 promoter methylation as a potential biomarker for the prognosis of esophageal squaous cell carcinoma
Methylation of microRNA (miRNA) promoters associated with diseases is a common epigenetic mechanism in the development of ...
The efficacy and safety of lenvatinib plus pembrolizumab in vulnerable patients with metastatic or recurrent endometrial cancer: a single institution experience
The efficacy and safety of lenvatinib plus pembrolizumab in vulnerable patients with metastatic or recurrent endometrial cancer: a single institution experience
Effective management with second-line therapy with the lenvatinib + pembrolizumab regimen for patients with ad...
Efficacy and safety of mosunetuzumab monotherapy for Japanese patients with relapsed/refractory follicular lymphoma: FLMOON-1
Efficacy and safety of mosunetuzumab monotherapy for Japanese patients with relapsed/refractory follicular lymphoma: FLMOON-1
In a global phase I/II study (GO29781; NCT02500407), single-agent mosunetuzumab had a manageable safety profile and induce...
Characterization of PSA dynamics and oncological outcomes in patients with metastatic hormone-sensitive prostate cancer treated with androgen receptor signaling inhibitors
Characterization of PSA dynamics and oncological outcomes in patients with metastatic hormone-sensitive prostate cancer treated with androgen receptor signaling inhibitors
This study investigated the characteristics of prostate-specific antigen (PSA) dynamics when androgen receptor signaling i...
Impact of presurgical systemic therapy on perioperative outcomes of renal cell carcinoma with inferior vena cava tumor thrombus
Impact of presurgical systemic therapy on perioperative outcomes of renal cell carcinoma with inferior vena cava tumor thrombus
Surgery for inferior vena cava tumor thrombus (IVC-TT) in patients with renal cell carcinoma (RCC) is highly invasive and ...
Evaluating the impact of atezolizumab on febrile neutropenia occurrence in patients with NSCLC undergoing chemotherapy in Japan: a real-world post-marketing database study
Evaluating the impact of atezolizumab on febrile neutropenia occurrence in patients with NSCLC undergoing chemotherapy in Japan: a real-world post-marketing database study
Febrile neutropenia (FN) is a recognised adverse event associated with chemotherapy. This study investigates the impact of...
Treatment-related skin reactions in enfortumab vedotin as a surrogate marker of survival and treatment response
Treatment-related skin reactions in enfortumab vedotin as a surrogate marker of survival and treatment response
Treatment-related skin reactions (TRSRs) induced by enfortumab vedotin (EV) targeting nectin-4 are among the most common a...
Age-related genomic alterations and chemotherapy sensitivity in osteosarcoma: insights from cancer genome profiling analyses
Age-related genomic alterations and chemotherapy sensitivity in osteosarcoma: insights from cancer genome profiling analyses
Osteosarcoma, the most common primary bone malignancy, has a complex genetic basis and two incidence peaks. In younger pat...
Improved prognosis of de novo metastatic prostate cancer after an introduction of life-prolonging agents for castration-resistant prostate cancer
Improved prognosis of de novo metastatic prostate cancer after an introduction of life-prolonging agents for castration-resistant prostate cancer
In Japan, since 2014, new treatments such as androgen receptor signaling inhibitors and cabazitaxel have become applicable...
Efficacy of androgen receptor signaling inhibitors in combination with androgen deprivation therapy for castration-sensitive metastatic prostate cancer: a retrospective analysis in a Japanese cohort
Efficacy of androgen receptor signaling inhibitors in combination with androgen deprivation therapy for castration-sensitive metastatic prostate cancer: a retrospective analysis in a Japanese cohort
This study aimed to evaluate the efficacy of androgen receptor signaling inhibitors (ARSIs) combined with androgen depriva...
Prognostic significance of lymph node metastasis of soft tissue sarcoma of the extremities. National cancer institute experience
Prognostic significance of lymph node metastasis of soft tissue sarcoma of the extremities. National cancer institute experience
Lymph node metastasis (LNM) in soft tissue sarcoma (STS) of the extremities is relatively rare. We aimed to evaluate the p...
Robotic dual-docking surgery for para-aortic lymphadenectomy in endometrial cancer: a prospective feasibility study
Robotic dual-docking surgery for para-aortic lymphadenectomy in endometrial cancer: a prospective feasibility study
The standard for robotic para-aortic lymphadenectomy has not been fully established. Para-aortic lymphadenectomy performed...
Prognostic significance of inflammatory markers in patients with advanced renal cell carcinoma receiving nivolumab plus ipilimumab
Prognostic significance of inflammatory markers in patients with advanced renal cell carcinoma receiving nivolumab plus ipilimumab
A useful biomarker for the efficacy of immune checkpoint inhibitors (ICIs) in advanced renal cell carcinoma (RCC) has not ...
Re-administration of platinum-based chemotherapy for recurrent endometrial cancer: an ancillary analysis of the SGSG-012/GOTIC-004/Intergroup study
Re-administration of platinum-based chemotherapy for recurrent endometrial cancer: an ancillary analysis of the SGSG-012/GOTIC-004/Intergroup study
We previously demonstrated the applicability of the concept of “platinum sensitivity” in recurrent endometrial...
Association between hospital palliative care team intervention volume and patient outcomes
Association between hospital palliative care team intervention volume and patient outcomes
The benefits of palliative care in patients with advanced cancer are well established. However, the effect of the skills o...
Measurement of the distance between tumor micro-foci and gross tumor in rectal cancer pathological specimens: implication on margin distance of clinical target volume treated with high-dose radiotherapy for rectal cancer
Measurement of the distance between tumor micro-foci and gross tumor in rectal cancer pathological specimens: implication on margin distance of clinical target volume treated with high-dose radiotherapy for rectal cancer
To measure the micro-foci distance away from gross tumor and to provide reference to create the clinical target volume (CT...
Prognostic value of pretreatment temporal muscle thickness after curative surgery for oral cavity squamous cell carcinoma
Prognostic value of pretreatment temporal muscle thickness after curative surgery for oral cavity squamous cell carcinoma
Sarcopenia is a poor prognostic factor in various diseases. Temporal muscle thickness (TMT) has been reported to be associ...
Correction to: Real‑world practice of estrogen therapy after surgery for endometrial cancer: a descriptive study using a Japanese claims database
Correction to: Real‑world practice of estrogen therapy after surgery for endometrial cancer: a descriptive study using a Japanese claims database
In Figs. 1, 2A, 5 of this article, the shadings were not shown; the Figs. 1, 2A, 5 sh...
A phase 2 study of mobocertinib as first-line treatment in Japanese patients with non-small cell lung cancer harboring EGFR exon 20 insertion mutations
A phase 2 study of mobocertinib as first-line treatment in Japanese patients with non-small cell lung cancer harboring EGFR exon 20 insertion mutations
Mobocertinib is a novel, synthetic, orally administered tyrosine kinase inhibitor that inhibits many activated forms of ep...
Long-term outcomes of the first prospective study of active surveillance for prostate cancer in Japan
Long-term outcomes of the first prospective study of active surveillance for prostate cancer in Japan
Active surveillance for prostate cancer was initiated in the early 2000s. We assessed the long-term outcomes of active sur...
Endoscopic and exoscopic surgery for brain tumors
Endoscopic and exoscopic surgery for brain tumors
Nerves and blood vessels must be protected during brain tumor surgery, which has traditionally relied on microscopes. In t...
Granulocyte colony-stimulating factor has the potential to attenuate the therapeutic efficacy of chemo-immunotherapy for extensive-stage small-cell lung cancer
Granulocyte colony-stimulating factor has the potential to attenuate the therapeutic efficacy of chemo-immunotherapy for extensive-stage small-cell lung cancer
Granulocyte colony-stimulating factor (G-CSF) has the potential to attenuate the anti-tumor immune responses of T-cells by...
Long-term consequences of positive surgical margin after partial nephrectomy for renal cell carcinoma: multi‐institutional analysis
Long-term consequences of positive surgical margin after partial nephrectomy for renal cell carcinoma: multi‐institutional analysis
The aim of the study was to determine the impact of positive surgical margins (PSM) after PN on very long-term recurrence ...
Comparative analysis of dual immune checkpoint inhibitor combination therapy versus immune checkpoint inhibitor plus tyrosine kinase inhibitor combination therapy for renal cell carcinoma with inferior vena cava tumor thrombosis
Comparative analysis of dual immune checkpoint inhibitor combination therapy versus immune checkpoint inhibitor plus tyrosine kinase inhibitor combination therapy for renal cell carcinoma with inferior vena cava tumor thrombosis
Whether immune checkpoint inhibitor (ICI) plus ICI combination therapy or ICI plus tyrosine kinase inhibitor (TKI) combina...
Clinical impact of a dose-escalation strategy for lenvatinib in differentiated thyroid cancer
Clinical impact of a dose-escalation strategy for lenvatinib in differentiated thyroid cancer
 Treatment options for patients with differentiated thyroid cancer (DTC) who experience disease progression on le...
A novel prognostic model of de novo metastatic hormone-sensitive prostate cancer to optimize treatment intensity
A novel prognostic model of de novo metastatic hormone-sensitive prostate cancer to optimize treatment intensity
The treatment and prognosis of de novo metastatic hormone-sensitive prostate cancer (mHSPC) vary. We established and valid...
Impact of interstitial lung disease gender-age-physiology index in surgically treated lung cancer
Impact of interstitial lung disease gender-age-physiology index in surgically treated lung cancer
The postoperative prognosis of patients with interstitial lung disease (ILD) and lung cancer is poor. Recently, the ILD-ge...
Load More
format_indent_increase