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Prognostic Effect of CEA Cut-Off in Patients with Resectable Colorectal Liver Metastases: A Meta-Analysis and Meta-Regression
Prognostic Effect of CEA Cut-Off in Patients with Resectable Colorectal Liver Metastases: A Meta-Analysis and Meta-Regression
Although preoperative carcinoembryonic antigen (CEA) is a variable used in most prognostic scores assessing the outcome of...
Validation of tumor burden score as a prognostic factor in colorectal cancer liver metastases patients: a retrospective analysis
Validation of tumor burden score as a prognostic factor in colorectal cancer liver metastases patients: a retrospective analysis
The assessment of resectability in patients with colorectal cancer (CRC) and multiple liver metastases is primarily a tech...
Patterns of Lymph Node Recurrence after Esophagectomy of pT2-3 N0M0 Esophageal Squamous Cell Carcinoma
Patterns of Lymph Node Recurrence after Esophagectomy of pT2-3 N0M0 Esophageal Squamous Cell Carcinoma
This study aims to elucidate the distribution patterns of lymph node recurrence (LNR) in patients with pT2-3N0M0 esophagea...
Statin use and Pancreatic Cancer: A Meta-analysis of its Association with Incidence in the General Population and Survival in Patients
Statin use and Pancreatic Cancer: A Meta-analysis of its Association with Incidence in the General Population and Survival in Patients
Statins have been appearing as a potential anti-cancer agent in numerous studies. The study aimed to unravel the impact of...
Gastric Carcinoma Patients with Advanced Pathological Lymph Node Stage Benefit from Postoperative Radiotherapy: A Retrospective Analysis
Gastric Carcinoma Patients with Advanced Pathological Lymph Node Stage Benefit from Postoperative Radiotherapy: A Retrospective Analysis
The relationship between regional pathological lymph node status and the benefit of postoperative radiotherapy for gastric...
Correlation between Tomographic and Histopathological Staging in Upfront Resected Gastric Cancer: Enhancing Diagnostic Accuracy in the Era of Perioperative Therapy
Correlation between Tomographic and Histopathological Staging in Upfront Resected Gastric Cancer: Enhancing Diagnostic Accuracy in the Era of Perioperative Therapy
This study aimed to assess the diagnostic accuracy of multidetector contrast-enhanced computerised tomography (MDCT) and t...
Adherence to Multidisciplinary Tumor Board Recommendations and Its Association with Survival: A Retrospective Observational Study of Colorectal Cancer Patients
Adherence to Multidisciplinary Tumor Board Recommendations and Its Association with Survival: A Retrospective Observational Study of Colorectal Cancer Patients
Multidisciplinary tumor boards (MTBs) intend to increase the quality of cancer care. Research on the association of adhere...
Melanoma and Colorectal Cancer as Second Primary Cancers: A Scoping Review of Their Association and the Underlying Biological, Lifestyle, and Genetic Factors
Melanoma and Colorectal Cancer as Second Primary Cancers: A Scoping Review of Their Association and the Underlying Biological, Lifestyle, and Genetic Factors
Second primary cancers (SPCs) are independent primary cancers that develop separately from pre-existing malignancies, dist...
Long-Term Oncological Outcomes After Complete Mesocolic Excision Versus Standard Resection for Right-Sided Colon Cancer: A Propensity Score Matching Analysis
Long-Term Oncological Outcomes After Complete Mesocolic Excision Versus Standard Resection for Right-Sided Colon Cancer: A Propensity Score Matching Analysis
Complete mesocolic excision (CME) has not gained wide diffusion, mainly due to its technical complexity and unclear oncolo...
Impact of Environmental Quality on Pancreatic Cancer Outcomes Post Pancreatoduodenectomy: A Retrospective Cohort Study
Impact of Environmental Quality on Pancreatic Cancer Outcomes Post Pancreatoduodenectomy: A Retrospective Cohort Study
The Environmental Quality Index (EQI), a composite measure of county-level environmental burden, has been linked to cancer...
Hepatic Yolk Sac Tumor: A Systematic Review of Presentation, Diagnosis, and Treatment
Hepatic Yolk Sac Tumor: A Systematic Review of Presentation, Diagnosis, and Treatment
Primary hepatic yolk sac tumor (HYST) is a rare, extragonadal germ cell neoplasm that arises in hepatic tissue. This revie...
Prehabilitation Reduces Occurrence of Anastomotic Leaks After Esophagectomy—A Retrospective Cohort Analysis and Meta-analysis
Prehabilitation Reduces Occurrence of Anastomotic Leaks After Esophagectomy—A Retrospective Cohort Analysis and Meta-analysis
Esophageal anastomotic leaks (EAL) after esophagectomy strongly increase postoperative mortality and morbidity. Identifyin...
Impact of Prehabilitation in Major Gastrointestinal Oncological Surgery: a Systematic Review
Impact of Prehabilitation in Major Gastrointestinal Oncological Surgery: a Systematic Review
Patients undergoing major gastrointestinal oncologic surgeries often present with frailty, sarcopenia, anemia, and comorbi...
Response Prediction to Neoadjuvant Chemoradiotherapy in Rectal Cancer Based on Systemic Inflammatory Markers (NLR, PLR, and LMR)
Response Prediction to Neoadjuvant Chemoradiotherapy in Rectal Cancer Based on Systemic Inflammatory Markers (NLR, PLR, and LMR)
This study aimed to evaluate whether systemic inflammatory markers—neutrophil-to-lymphocyte ratio (NLR), platelet-to...
Radiofrequency Ablation Technology in Liver Malignancies: A Systematic Review of Economic Evaluations
Radiofrequency Ablation Technology in Liver Malignancies: A Systematic Review of Economic Evaluations
Liver malignancies, including hepatocellular carcinoma (HCC), present significant treatment challenges, with limited curat...
Prognostic Impact of Thoracic Extra-regional Lymph Node Metastasis Defined By the 12th Japanese Classification Following Definitive Radiotherapy for Esophageal Squamous Cell Carcinoma
Prognostic Impact of Thoracic Extra-regional Lymph Node Metastasis Defined By the 12th Japanese Classification Following Definitive Radiotherapy for Esophageal Squamous Cell Carcinoma
The aim of this study was to investigate the prognostic impact of thoracic extra-regional lymph node metastasis (M1b-LYM, ...
Clinical Efficacy and Safety of Apatinib Combined with Irinotecan in HER2-negative Patients with Advanced Gastric or Gastroesophageal Junction Adenocarcinoma after First-Line Treatment Failure: A Single-Arm, Single-Center Retrospective Study
Clinical Efficacy and Safety of Apatinib Combined with Irinotecan in HER2-negative Patients with Advanced Gastric or Gastroesophageal Junction Adenocarcinoma after First-Line Treatment Failure: A Single-Arm, Single-Center Retrospective Study
In this study, the clinical efficacy and safety of apatinib combined with irinotecan in HER2-negative patients with first-...
Factors Influencing Immunotherapy Utilization in Stage IV Pancreatic Cancer: Impact of Race and Socioeconomics in the U.S
Factors Influencing Immunotherapy Utilization in Stage IV Pancreatic Cancer: Impact of Race and Socioeconomics in the U.S
Pancreatic ductal adenocarcinoma (PDAC), a highly lethal cancer with a poor prognosis, is expected to become the second de...
Immunohistochemical Expression of ROR2 in Gastrointestinal Stromal Tumor
Immunohistochemical Expression of ROR2 in Gastrointestinal Stromal Tumor
Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors affecting the digestive tract, comprising ap...
Role of Interleukins in Pancreatic Cancer: A Literature Review
Role of Interleukins in Pancreatic Cancer: A Literature Review
This review article summarizes the pathophysiological aspects of interleukins (ILs) including IL-1, IL-2, IL-3, IL-4, IL-5...
Exceptional Response to Pembrolizumab in HER2-Positive Gallbladder Carcinoma with High Tumor Mutational Burden
Exceptional Response to Pembrolizumab in HER2-Positive Gallbladder Carcinoma with High Tumor Mutational Burden
Patients with advanced cholangiocarcinoma, including gallbladder cancer, typically have a poor prognosis owing to limited ...
Both Th1 and Th2 CD4 + T-Cell Lineage Infiltrations Decrease in Post-hematopoietic Stem Cell Transplantation Colon Adenoma
Both Th1 and Th2 CD4 + T-Cell Lineage Infiltrations Decrease in Post-hematopoietic Stem Cell Transplantation Colon Adenoma
As long-term survival improves after allogeneic hematopoietic stem cell transplantation (HSCT), the risk for secondary sol...
Patterns and Predictors of Recurrence After Curative Resection of Colorectal Liver Metastasis (CRLM)
Patterns and Predictors of Recurrence After Curative Resection of Colorectal Liver Metastasis (CRLM)
Our study aims to determine the predictors and patterns of relapses after curative colorectal liver metastasis (CRLM) rese...
Synergistic Effects of Fruquintinib Combined with Immune Checkpoint Inhibitors on Metastatic Colorectal Cancer
Synergistic Effects of Fruquintinib Combined with Immune Checkpoint Inhibitors on Metastatic Colorectal Cancer
Fruquintinib has received approval for the management of patients with chemotherapy-resistant metastatic colorectal cancer...
Primary Intrahepatic Mesothelioma: Case Series and Systematic Review of Literature
Primary Intrahepatic Mesothelioma: Case Series and Systematic Review of Literature
Primary intrahepatic mesothelioma (PIHMM) has been rarely reported. Its typical clinical presentation, radiological featur...
Colorectal Leiomyosarcoma: Demographics Patterns, Treatment Characteristics, and Survival Analysis in the U.S. Population
Colorectal Leiomyosarcoma: Demographics Patterns, Treatment Characteristics, and Survival Analysis in the U.S. Population
Colorectal leiomyosarcoma (CR-LMS) is a rare neoplasm arising from smooth muscle cells. It accounts for less than 0.1% of ...
Comparative Cost-Effectiveness of Gemcitabine and Cisplatin in Combination with S-1, Durvalumab, or Pembrolizumab as First-Line Triple Treatment for Advanced Biliary Tract Cancer
Comparative Cost-Effectiveness of Gemcitabine and Cisplatin in Combination with S-1, Durvalumab, or Pembrolizumab as First-Line Triple Treatment for Advanced Biliary Tract Cancer
The clinical effectiveness of triple chemotherapy consisting of gemcitabine, cisplatin plus either S-1 (GCS), durvalumab (...
Advanced Imaging of Hepatocellular Carcinoma: A Review of Current and Novel Techniques
Advanced Imaging of Hepatocellular Carcinoma: A Review of Current and Novel Techniques
Hepatocellular carcinoma (HCC) is the most common primary carcinoma arising from the liver. Although HCC can arise de novo...
Temporal Trends in Racial and Gender Disparities of Early Onset Colorectal Cancer in the United States: An Analysis of the CDC WONDER Database
Temporal Trends in Racial and Gender Disparities of Early Onset Colorectal Cancer in the United States: An Analysis of the CDC WONDER Database
The mortality rates of early-onset colorectal cancer (EOCRC) have surged globally over the past two decades. While the und...
Long-Term Survivor of Intrahepatic Cholangiocarcinoma for over 18 Years: Case Study with Longitudinal Histo-molecular and Tumor Immune Microenvironment Characterization and Systematic Review of the Literature
Long-Term Survivor of Intrahepatic Cholangiocarcinoma for over 18 Years: Case Study with Longitudinal Histo-molecular and Tumor Immune Microenvironment Characterization and Systematic Review of the Literature
Intrahepatic cholangiocarcinoma is a biliary neoplasm usually showing a dismal prognosis. In early stages, surgical resect...
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