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Combined hepatocellular-cholangiocarcinoma: biology, diagnosis, and management
Combined hepatocellular-cholangiocarcinoma: biology, diagnosis, and management
Background Combined hepatocellular-cholangiocarcinoma (cHCC-iCCA) is a rare type of primary liver cancer displaying charac...
HBV DNA Integration into Telomerase or MLL4 Genes and TERT Promoter Point Mutation as Three Independent Signatures in Subgrouping HBV-related HCC with distinct features
HBV DNA Integration into Telomerase or MLL4 Genes and TERT Promoter Point Mutation as Three Independent Signatures in Subgrouping HBV-related HCC with distinct features
Introduction: A set of genetic mutations to classify hepatocellular carcinoma (HCC) useful to clinical studies is an unmet...
Real-time fluorescence imaging to identify cholangiocarcinoma in the extrahepatic biliary tree using an enzyme-activatable probe
Real-time fluorescence imaging to identify cholangiocarcinoma in the extrahepatic biliary tree using an enzyme-activatable probe
Introduction Complete resection is the only possible treatment for cholangiocarcinoma in the extrahepatic biliary tree (eC...
Albumin-Bilirubin Grade Analyses of Atezolizumab plus Bevacizumab versus Sorafenib in Patients with Unresectable Hepatocellular Carcinoma: A Post Hoc Analysis of the Phase III IMbrave150 Study
Albumin-Bilirubin Grade Analyses of Atezolizumab plus Bevacizumab versus Sorafenib in Patients with Unresectable Hepatocellular Carcinoma: A Post Hoc Analysis of the Phase III IMbrave150 Study
<b><i>Introduction:</i></b> Atezolizumab + bevacizumab showed survival benefit in patients with un...
Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2022 Edition)
Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2022 Edition)
Background: Primary liver cancer, around 75%–85% are hepatocellular carcinoma in China, is the fourth most common malignan...
TACE for treatment-naive HCC has different treatment effects depending on central or peripheral tumor-location
TACE for treatment-naive HCC has different treatment effects depending on central or peripheral tumor-location
Introduction: The purpose of this study was to evaluate the treatment efficacy of transcatheter arterial chemo-embolizatio...
Genomic and Immune Features in an Intrahepatic Cholangiocarcinoma Patient with Microsatellite Instability-High Suffered Rapid Acquired Resistance to PD-1 Inhibitor
Genomic and Immune Features in an Intrahepatic Cholangiocarcinoma Patient with Microsatellite Instability-High Suffered Rapid Acquired Resistance to PD-1 Inhibitor
Introduction: Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive liver malignancy with poor prognosis. Recently,...
Survival Trends in Sorafenib for Advanced Hepatocellular Carcinoma: A Reconstructed Individual Patient Data Meta-analysis of Randomized Trials
Survival Trends in Sorafenib for Advanced Hepatocellular Carcinoma: A Reconstructed Individual Patient Data Meta-analysis of Randomized Trials
Background: Emerging data suggest that outcomes for advanced hepatocellular carcinoma (HCC) treated with sorafenib may hav...
Reply to “Surgical resection or radiofrequency ablation for small hepatocellular carcinoma”
Reply to “Surgical resection or radiofrequency ablation for small hepatocellular carcinoma”
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Computed Tomography-Defined Sarcopenia in Outcomes of Patients with Unresectable Hepatocellular Carcinoma Undergoing Radioembolization: Assessment with Total Abdominal, Psoas, and Paraspinal Muscles
Computed Tomography-Defined Sarcopenia in Outcomes of Patients with Unresectable Hepatocellular Carcinoma Undergoing Radioembolization: Assessment with Total Abdominal, Psoas, and Paraspinal Muscles
<b><i>Introduction:</i></b> Sarcopenia is an adverse prognostic factor in patients with liver cirr...
Definitive liver radiotherapy for intrahepatic cholangiocarcinoma with extrahepatic metastases
Definitive liver radiotherapy for intrahepatic cholangiocarcinoma with extrahepatic metastases
Introduction: Tumor-related liver failure (TRLF) is the most common cause of death in patients with intrahepatic cholangio...
Contrast-Enhanced Ultrasound Liver Imaging Reporting and Data System in Hepatocellular Carcinoma ≤5 cm: Biological Characteristics and Patient Outcomes
Contrast-Enhanced Ultrasound Liver Imaging Reporting and Data System in Hepatocellular Carcinoma ≤5 cm: Biological Characteristics and Patient Outcomes
<b><i>Introduction:</i></b> The present study aimed to evaluate the influence of biological charac...
Surveillance, Diagnosis, and Treatment Outcome of Hepatocellular Carcinoma in Japan: 2023 Update
Surveillance, Diagnosis, and Treatment Outcome of Hepatocellular Carcinoma in Japan: 2023 Update
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Albumin-Bilirubin Grade Analyses of Atezolizumab Plus Bevacizumab vs Sorafenib in Patients With Unresectable Hepatocellular Carcinoma: A Post Hoc Analysis of the Phase III IMbrave150 Study
Albumin-Bilirubin Grade Analyses of Atezolizumab Plus Bevacizumab vs Sorafenib in Patients With Unresectable Hepatocellular Carcinoma: A Post Hoc Analysis of the Phase III IMbrave150 Study
Introduction: Atezolizumab + bevacizumab showed survival benefit in patients with unresectable hepatocellular carcinoma (H...
Pembrolizumab as Second-Line Therapy for Advanced Hepatocellular Carcinoma: Longer-Term Follow-Up From the Phase 3 KEYNOTE-240 Trial
Pembrolizumab as Second-Line Therapy for Advanced Hepatocellular Carcinoma: Longer-Term Follow-Up From the Phase 3 KEYNOTE-240 Trial
Introduction: KEYNOTE-240 showed a favorable benefit/risk profile for pembrolizumab versus placebo in patients with sorafe...
Association Between Smoking Cessation and the Risk of Cholangiocarcinoma and Ampulla of Vater Cancer: A Nationwide Cohort Study
Association Between Smoking Cessation and the Risk of Cholangiocarcinoma and Ampulla of Vater Cancer: A Nationwide Cohort Study
Introduction: The association between smoking cessation and intrahepatic and extrahepatic cholangiocarcinoma (iCCA and eCC...
Impact of Intrahepatic External Beam Radiotherapy in Advanced Hepatocellular Carcinoma Patients Treated with Tyrosine Kinase Inhibitors
Impact of Intrahepatic External Beam Radiotherapy in Advanced Hepatocellular Carcinoma Patients Treated with Tyrosine Kinase Inhibitors
Introduction: We aimed to investigate whether concurrent use of intrahepatic external beam radiotherapy (EBRT) is a viable...
Achievement of Complete Response and Drug-free Status by Atezolizumab Plus Bevacizumab Combined with or without Curative Conversion in Patients with Transarterial Chemoembolization-Unsuitable, Intermediate-stage Hepatocellular Carcinoma: A Multicenter Proof-of-Concept Study
Achievement of Complete Response and Drug-free Status by Atezolizumab Plus Bevacizumab Combined with or without Curative Conversion in Patients with Transarterial Chemoembolization-Unsuitable, Intermediate-stage Hepatocellular Carcinoma: A Multicenter Proof-of-Concept Study
Introduction: Atezolizumab plus bevacizumab therapy is extremely effective in the treatment of intermediate-stage hepatoce...
Contrast-enhanced ultrasound Liver Imaging Reporting and Data System (LI-RADS) in hepatocellular carcinoma ≤ 5cm: biological characteristics and patient outcomes
Contrast-enhanced ultrasound Liver Imaging Reporting and Data System (LI-RADS) in hepatocellular carcinoma ≤ 5cm: biological characteristics and patient outcomes
Introduction: The present study aimed to evaluate the influence of biological characteristics of hepatocellular carcinoma ...
Optimizing survival benefit by surgical resection by the seven-eleven criteria in Barcelona clinic liver cancer stage A/B hepatocellular carcinoma beyond the Milan criteria
Optimizing survival benefit by surgical resection by the seven-eleven criteria in Barcelona clinic liver cancer stage A/B hepatocellular carcinoma beyond the Milan criteria
Introduction: Optimal treatment of hepatocellular carcinoma (HCC) beyond the Milan criteria is in debate. We aimed to ide...
Efficacy of Local Treatment in Lymph Node Metastasis from Hepatocellular Carcinoma
Efficacy of Local Treatment in Lymph Node Metastasis from Hepatocellular Carcinoma
Introduction: We aimed to investigate the significance of lymph node metastasis from hepatocellular carcinoma and the effi...
Long-term regression after discontinuation of regorafenib administered for sorafenib-refractory hepatocellular carcinoma
Long-term regression after discontinuation of regorafenib administered for sorafenib-refractory hepatocellular carcinoma
A patient with hepatocellular carcinoma(HCC) staged Barcelona Clinic for Liver Cancer stage B started chemotherapy because...
Predictive and prognostic potential of liver function assessment in patients with advanced hepatocellular carcinoma: a systematic literature review
Predictive and prognostic potential of liver function assessment in patients with advanced hepatocellular carcinoma: a systematic literature review
Introduction We conducted a systematic literature review to assess the utility of liver function assessments for predicti...
The 12th Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE 2022)
The 12th Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE 2022)
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