SCI Abstract

search
+
TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis
TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis
TWIST1 is known to promote glycolysis and contribute to pancreatic cancer development; however, its underlying mechanisms ...
Comprehensive analysis of α2,3-sialyltransferases as prognostic biomarkers and immunotherapy targets in kidney renal clear cell carcinoma
Comprehensive analysis of α2,3-sialyltransferases as prognostic biomarkers and immunotherapy targets in kidney renal clear cell carcinoma
Kidney renal clear cell carcinoma (KIRC), a therapy-resistant aggressive kidney cancer, exhibits resistance to immune chec...
Do wolframin, P-glycoprotein, and GRP78/BiP cooperate to alter the response of L1210 cells to endoplasmic reticulum stress or drug sensitivity?
Do wolframin, P-glycoprotein, and GRP78/BiP cooperate to alter the response of L1210 cells to endoplasmic reticulum stress or drug sensitivity?
In previous research, we revealed that murine leukemia cells L1210 with induced expression of P-glycoprotein (P-gp, a memb...
Characterization of G2/M checkpoint classifier for personalized treatment in uterine corpus endometrial carcinoma
Characterization of G2/M checkpoint classifier for personalized treatment in uterine corpus endometrial carcinoma
Uterine Corpus Endometrial Carcinoma (UCEC) is a highly heterogeneous tumor, and limitations in current diagnostic methods...
PI3Kδ inhibitor linperlisib combined with gemcitabine and oxaliplatin for relapsed or refractory diffuse large B-cell lymphoma: a multicenter, single-arm phase Ib/II trial
PI3Kδ inhibitor linperlisib combined with gemcitabine and oxaliplatin for relapsed or refractory diffuse large B-cell lymphoma: a multicenter, single-arm phase Ib/II trial
This investigation assessed the therapeutic potential of combining linperlisib, a targeted inhibitor of phosphatidylinosit...
Serum exosomal small nucleolar RNA (snoRNA) signatures as a predictive biomarker for benign and malignant pulmonary nodules
Serum exosomal small nucleolar RNA (snoRNA) signatures as a predictive biomarker for benign and malignant pulmonary nodules
Low-dose CT (LDCT) is increasingly recognized as the preferred method for detecting pulmonary nodules. However, distinguis...
RhoA-ROCK2 signaling possesses complex pathophysiological functions in cancer progression and shows promising therapeutic potential
RhoA-ROCK2 signaling possesses complex pathophysiological functions in cancer progression and shows promising therapeutic potential
The Rho GTPase signaling pathway is responsible for cell-specific processes, including actin cytoskeleton organization, ce...
CD74 is a potential biomarker predicting the response to immune checkpoint blockade
CD74 is a potential biomarker predicting the response to immune checkpoint blockade
Immune checkpoint blockade (ICB) has been improving the patient outcome in multiple cancer types. However, not all patient...
Pan-cancer analysis of Sp1 with a focus on immunomodulatory roles in gastric cancer
Pan-cancer analysis of Sp1 with a focus on immunomodulatory roles in gastric cancer
Sp1, a transcription factor, regulates essential cellular processes and plays important tumorigenic roles across diverse c...
Targeting of 3D oral cancer spheroids by αVβ6 integrin using near-infrared peptide-conjugated IRDye 680
Targeting of 3D oral cancer spheroids by αVβ6 integrin using near-infrared peptide-conjugated IRDye 680
In the treatment of oral cavity cancer, margin status is one of the most critical prognostic factors. Positive margins are...
LINC00665 promotes the progression and immune evasion of lung cancer by facilitating the translation of TCF7 protein through dependence on IRES
LINC00665 promotes the progression and immune evasion of lung cancer by facilitating the translation of TCF7 protein through dependence on IRES
To investigate the influence of LINC00665 on the development and immune evasion of lung cancer. Tumor tissues and correspo...
Blood-based molecular and cellular biomarkers of early response to neoadjuvant PD-1 blockade in patients with non-small cell lung cancer
Blood-based molecular and cellular biomarkers of early response to neoadjuvant PD-1 blockade in patients with non-small cell lung cancer
Despite the improved survival observed in PD-1/PD-L1 blockade therapy, a substantial proportion of cancer patients, includ...
Human peritoneal fluid exerts ovulation- and nonovulation-sourced oncogenic activities on transforming fallopian tube epithelial cells
Human peritoneal fluid exerts ovulation- and nonovulation-sourced oncogenic activities on transforming fallopian tube epithelial cells
Secretory cells in the fallopian tube fimbria epithelium (FTE) are regarded as the main cells of origin of ovarian high-gr...
Prognostic significance of hemoglobin, albumin, lymphocyte, and platelet (HALP) score in breast cancer: a propensity score-matching study
Prognostic significance of hemoglobin, albumin, lymphocyte, and platelet (HALP) score in breast cancer: a propensity score-matching study
The hemoglobin-albumin-lymphocyte-platelet (HALP) score functions as a comprehensive index that assesses the systemic infl...
ACADL-YAP axis activity in non-small cell lung cancer carcinogenicity
ACADL-YAP axis activity in non-small cell lung cancer carcinogenicity
The role of Acyl-CoA dehydrogenase long chain (ACADL) in different tumor types had different inhibiting or promoting effec...
Emerging trends in the coexistence of primary lung Cancer and hematologic malignancy: a comprehensive analysis of clinicopathological features and genetic abnormalities
Emerging trends in the coexistence of primary lung Cancer and hematologic malignancy: a comprehensive analysis of clinicopathological features and genetic abnormalities
The incidence of multiple primary cancers (MPC), especially involving primary lung cancer (PLC) and primary hematologic ma...
SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway
SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway
SLC25A17, a peroxisomal solute carrier, has been implicated in various physiological and pathological processes. However, ...
Genome-wide CRISPR screen identifies ESPL1 limits the response of gastric cancer cells to apatinib
Genome-wide CRISPR screen identifies ESPL1 limits the response of gastric cancer cells to apatinib
Apatinib was the first anti-angiogenic agent approved for treatment of metastatic gastric cancer (GC). However, the emerge...
Leveraging a disulfidptosis‑related lncRNAs signature for predicting the prognosis and immunotherapy of glioma
Leveraging a disulfidptosis‑related lncRNAs signature for predicting the prognosis and immunotherapy of glioma
Gliomas, a prevalent form of primary brain tumors, are linked with a high mortality rate and unfavorable prognoses. Disulf...
The emerging role of glycolysis and immune evasion in gastric cancer
The emerging role of glycolysis and immune evasion in gastric cancer
Gastric cancer (GC) is the fifth most common malignancy and the third leading cause of cancer-related deaths worldwide. Si...
Tumour cells can escape antiproliferative pressure by interferon-β through immunoediting of interferon receptor expression
Tumour cells can escape antiproliferative pressure by interferon-β through immunoediting of interferon receptor expression
Type I interferons (IFNs) play a central role not only in innate immunity against viral infection, but also in the antitum...
Single-cell RNA sequencing in cancer research: discovering novel biomarkers and therapeutic targets for immune checkpoint blockade
Single-cell RNA sequencing in cancer research: discovering novel biomarkers and therapeutic targets for immune checkpoint blockade
Immune checkpoint blockade (ICB) has become a promising strategy in treating advanced cancers, providing significant survi...
Technical comparison of Abbott’s UroVysion® and Biocare’s CytoFISH urine fluorescence in situ hybridization (FISH) assays
Technical comparison of Abbott’s UroVysion® and Biocare’s CytoFISH urine fluorescence in situ hybridization (FISH) assays
This study aims to compare the technical performance of Abbott’s UroVysion and Biocare’s CytoFISH urine cytolo...
The nexus of natural killer cells and melanoma tumor microenvironment: crosstalk, chemotherapeutic potential, and innovative NK cell-based therapeutic strategies
The nexus of natural killer cells and melanoma tumor microenvironment: crosstalk, chemotherapeutic potential, and innovative NK cell-based therapeutic strategies
The metastasis of melanoma cells to regional lymph nodes and distant sites is an important contributor to cancer-related m...
Disclosing a metabolic signature of cisplatin resistance in MDA-MB-231 triple-negative breast cancer cells by NMR metabolomics
Disclosing a metabolic signature of cisplatin resistance in MDA-MB-231 triple-negative breast cancer cells by NMR metabolomics
This work compared the metabolic profile of a parental MDA-MB-231 cisplatin-sensitive triple negative breast cancer (TNBC)...
Single-cell histone chaperones patterns guide intercellular communication of tumor microenvironment that contribute to breast cancer metastases
Single-cell histone chaperones patterns guide intercellular communication of tumor microenvironment that contribute to breast cancer metastases
Histone chaperones (HCs) are crucial for governing genome stability and gene expression in multiple cancers. However, the ...
The function and mechanism of PSMD14 in promoting progression and resistance to anlotinib in osteosarcoma
The function and mechanism of PSMD14 in promoting progression and resistance to anlotinib in osteosarcoma
Osteosarcoma is a rare bone malignancy that frequently affects adolescents and poses formidable obstacles in its advanced ...
Circular RNA circEYA3 promotes the radiation resistance of hepatocellular carcinoma via the IGF2BP2/DTX3L axis
Circular RNA circEYA3 promotes the radiation resistance of hepatocellular carcinoma via the IGF2BP2/DTX3L axis
Hepatocellular carcinoma (HCC) has a high incidence and mortality rate despite various treatment options, including 125I s...
Prognostic significance of Lymphocyte-activation gene 3 (LAG3) in patients with solid tumors: a systematic review, meta-analysis and pan-cancer analysis
Prognostic significance of Lymphocyte-activation gene 3 (LAG3) in patients with solid tumors: a systematic review, meta-analysis and pan-cancer analysis
Lymphocyte-activation gene 3 (LAG3) is a recently discovered immune checkpoint molecule that has been linked to immunosupp...
A pan-cancer analysis indicates long noncoding RNA HAND2-AS1 as a potential prognostic, immunomodulatory and therapeutic biomarker in various cancers including colorectal adenocarcinoma
A pan-cancer analysis indicates long noncoding RNA HAND2-AS1 as a potential prognostic, immunomodulatory and therapeutic biomarker in various cancers including colorectal adenocarcinoma
The HAND2-AS1 (HAND2 Antisense RNA 1) Long noncoding RNA (lncRNA) has emerged as a participant in the initiation of variou...
Load More
format_indent_increase