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Tumor Treating Fields (TTFields) Therapy in Unresectable Pleural Mesothelioma: Overview of Efficacy, Safety, and Future Outlook
Tumor Treating Fields (TTFields) Therapy in Unresectable Pleural Mesothelioma: Overview of Efficacy, Safety, and Future Outlook
Pleural mesothelioma is an incurable cancer with unmet diagnostic and therapeutic needs. Due to its pattern of local sprea...
The Improving Outcomes in Relapsed-Refractory Diffuse Large B Cell Lymphoma: The Role of CAR T-Cell Therapy
The Improving Outcomes in Relapsed-Refractory Diffuse Large B Cell Lymphoma: The Role of CAR T-Cell Therapy
Diffuse large B cell lymphoma, not otherwise specified (DLBCL-NOS) is the most common aggressive lymphoma and can be cured...
Advances in Targeted Therapy for Metastatic Prostate Cancer
Advances in Targeted Therapy for Metastatic Prostate Cancer
Over the past few years, treatment for advanced prostate cancer has begun shifting away from a one-size-fits-all approach ...
Addressing Sexual Health in Breast Cancer Survivors: Evidence-Based Practices and Clinical Considerations
Addressing Sexual Health in Breast Cancer Survivors: Evidence-Based Practices and Clinical Considerations
Sexual health concerns are extremely prevalent among breast cancer survivors. The treatments used to treat and cure breast...
Role of Radiotherapy in PCNSL within the Current Therapeutic Landscape: a Comprehensive Review
Role of Radiotherapy in PCNSL within the Current Therapeutic Landscape: a Comprehensive Review
The therapeutic landscape for primary central nervous system lymphoma (PCNSL) continues to evolve, raising critical questi...
Immunotherapy-Boosted Stereotactic Ablative Radiotherapy in Inoperable Early-Stage Non-Small Cell Lung Cancer
Immunotherapy-Boosted Stereotactic Ablative Radiotherapy in Inoperable Early-Stage Non-Small Cell Lung Cancer
The combination of stereotactic ablative radiotherapy (SABR) with immune checkpoint inhibitors, known as iSABR, marks a si...
Epithelioid Hemangioendothelioma: Treatment Landscape and Innovations for an Ultra-Rare Sarcoma
Epithelioid Hemangioendothelioma: Treatment Landscape and Innovations for an Ultra-Rare Sarcoma
Epithelioid hemangioendothelioma (EHE) is an ultra-rare sarcoma with a paucity of data on best practices for management. P...
Research Progress of Natural Compounds from Chinese Herbal Medicine in the Treatment of Melanoma
Research Progress of Natural Compounds from Chinese Herbal Medicine in the Treatment of Melanoma
Melanoma is a malignant tumor that originates from activated or genetically altered epidermal melanocytes, resulting from ...
Nanomedicine-Based Treatments for Rare and Aggressive Ocular Cancers: Advances in Drug Delivery
Nanomedicine-Based Treatments for Rare and Aggressive Ocular Cancers: Advances in Drug Delivery
Ocular cancers, though rare, present significant therapeutic challenges due to their aggressive nature, high metastatic po...
Unmasking the Rare but Lethal Cardiac Complications of Immune Checkpoint Inhibitor Therapy: A Review of Mechanisms, Risk Factors, and Management Strategies
Unmasking the Rare but Lethal Cardiac Complications of Immune Checkpoint Inhibitor Therapy: A Review of Mechanisms, Risk Factors, and Management Strategies
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by enabling the immune system to effectively targ...
The Evolving Landscape of Ovarian Cancer: Innovations in Biotechnology and Artificial Intelligence- Based Screening and Treatment
The Evolving Landscape of Ovarian Cancer: Innovations in Biotechnology and Artificial Intelligence- Based Screening and Treatment
Ovarian Cancer (OC) is a serious health problem that affects a great number of women globally. It is still one of the dead...
Desmoplastic Small Round Cell Tumors and the Role of Androgen Receptors
Desmoplastic Small Round Cell Tumors and the Role of Androgen Receptors
Desmoplastic small round cell tumor (DSRCT) is an aggressive soft-tissue sarcoma driven by the EWSR1::WT1 fusion protein r...
Interventional Therapies to Treat Cancer Associated Pain
Interventional Therapies to Treat Cancer Associated Pain
Cancer associated pain (CAP) is challenging to treat and may be complicated by type of cancer, location, presence of metas...
Looking Beyond the Surface: Olutasidenib and Ivosidenib for Treatment of mIDH1 Acute Myeloid Leukemia
Looking Beyond the Surface: Olutasidenib and Ivosidenib for Treatment of mIDH1 Acute Myeloid Leukemia
Mutations in isocitrate dehydrogenase-1 (IDH1) are recurrent in several malignancies and prevalent in acute myeloid leukem...
An Update on the Management of Rectal Neuroendocrine Neoplasms
An Update on the Management of Rectal Neuroendocrine Neoplasms
Rectal neuroendocrine neoplasms (NENs) are increasing in incidence. Most lesions are low grade, well-differentiated neuroe...
Respiratory Depression Associated with Opioids: A Narrative Review
Respiratory Depression Associated with Opioids: A Narrative Review
All opioids have a risk of causing respiratory depression and reduced cerebral circulation. Fentanyl has the greatest risk...
Current Drug Resistance Mechanisms and Treatment Options in Gastrointestinal Stromal Tumors: Summary and Update
Current Drug Resistance Mechanisms and Treatment Options in Gastrointestinal Stromal Tumors: Summary and Update
Gastrointestinal stromal tumor (GIST) is characterized by well-defined oncogenes. Despite the significant improvement in t...
Tarlatamab-dlle: A New Hope for Patients with Extensive-Stage Small-Cell Lung Cancer
Tarlatamab-dlle: A New Hope for Patients with Extensive-Stage Small-Cell Lung Cancer
Lung cancer is expected to contribute to about 0.234 million new cases and about 0.125 million mortalities in the United S...
Updates in Treatment of HER2-positive Metastatic Breast Cancer
Updates in Treatment of HER2-positive Metastatic Breast Cancer
The therapeutic landscape for HER2-positive metastatic breast cancer has exploded in the last two decades following the in...
New Therapeutic Targets in RAS Wild-type Pancreatic Cancer
New Therapeutic Targets in RAS Wild-type Pancreatic Cancer
The landscape of treatment of advanced PDAC is witnessing significant changes. This is in part due to the advent of molecu...
Molecular Secrets Revealed: How Diabetes may be Paving the Way for Leukemia
Molecular Secrets Revealed: How Diabetes may be Paving the Way for Leukemia
Type 2 Diabetes Mellitus (T2DM) and leukemia are two major global health concerns, both contributing significantly to morb...
“When Less is More”: Paradigm Shifts in Radiation Treatment for Early-Stage Breast Cancer
“When Less is More”: Paradigm Shifts in Radiation Treatment for Early-Stage Breast Cancer
Recent advancements in the treatment of early-stage breast cancer have significantly shifted the radiotherapy landscape. T...
From Subtypes to Solutions: Integrating CMS Classification with Precision Therapeutics in Colorectal Cancer
From Subtypes to Solutions: Integrating CMS Classification with Precision Therapeutics in Colorectal Cancer
The biological heterogeneity of colorectal cancer makes its molecular characteristics essential for therapeutic decision-m...
Treatment Options for IDH-Mutant Malignant Gliomas
Treatment Options for IDH-Mutant Malignant Gliomas
As the peak incidence of isocitrate dehydrogenase (IDH)-mutant gliomas is amongst young adults, there is a need to balance...
A Review of Current and Future Antibody Drug Conjugates in Breast Cancer
A Review of Current and Future Antibody Drug Conjugates in Breast Cancer
Antibody–drug conjugates (ADCs) are a novel class of anti-cancer agents that have changed the standard of care for p...
Unveiling the Potential of Cyclin-Dependent Kinases 4 and 6 Inhibitors Beyond Progression in Hormone Receptor Positive/Human Epidermal Growth Factor Negative Advanced Breast Cancer – A Clinical Review
Unveiling the Potential of Cyclin-Dependent Kinases 4 and 6 Inhibitors Beyond Progression in Hormone Receptor Positive/Human Epidermal Growth Factor Negative Advanced Breast Cancer – A Clinical Review
Cyclin-dependent kinases 4 and 6 inhibitors (CDK4/6i) have revolutionized the management of hormone receptor-positive (HR&...
Who Should Receive Immunotherapy for Advanced Gastroesophageal Cancer?
Who Should Receive Immunotherapy for Advanced Gastroesophageal Cancer?
This paper shines a light on the exciting progress being made in using immunotherapy to treat advanced gastroesophageal ca...
Pioneering the Way: The Revolutionary Potential of Antibody–Drug Conjugates in NSCLC
Pioneering the Way: The Revolutionary Potential of Antibody–Drug Conjugates in NSCLC
Despite targeted therapy and immunotherapy being recognized as established frontline treatments for advanced non-small cel...
Role of Metastasis-Directed Therapy in Genitourinary Cancers
Role of Metastasis-Directed Therapy in Genitourinary Cancers
The treatment of oligometastatic genitourinary cancers is a rapidly advancing field with ablative radiotherapy as one of t...
Post-Radiotherapy Dysphagia in Head and Neck Cancer: Current Management by Speech-Language Pathologists
Post-Radiotherapy Dysphagia in Head and Neck Cancer: Current Management by Speech-Language Pathologists
Dysphagia, difficulty in eating and drinking, remains the most common side effect of radiotherapy treatment for head and n...
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