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HPV-Mediated Radiosensitivity in Oropharyngeal Squamous Cell Carcinoma: Molecular Mechanisms and Cellular Pathways
HPV-Mediated Radiosensitivity in Oropharyngeal Squamous Cell Carcinoma: Molecular Mechanisms and Cellular Pathways
While the oncogenic potential of HPV has been well-established in other disease sites (e.g. cervix, vulva, anus), it is in...
Mesenteric Fibrosis in Neuroendocrine Neoplasms: a Systematic Review of New Thoughts on Causation and Potential Treatments
Mesenteric Fibrosis in Neuroendocrine Neoplasms: a Systematic Review of New Thoughts on Causation and Potential Treatments
Mesenteric fibrosis (MF) is a hallmark of small intestinal neuroendocrine neoplasms (SI-NEN) and is frequently associated ...
Targeting Lung Cancer with Precision: The ADC Therapeutic Revolution
Targeting Lung Cancer with Precision: The ADC Therapeutic Revolution
This review explores the evolving role of antibody–drug conjugates (ADCs) in lung cancer treatment, with a focus on ...
Plant Terpenoids in Combination with Conventional Therapeutics in Colorectal Cancer: A Promising Option
Plant Terpenoids in Combination with Conventional Therapeutics in Colorectal Cancer: A Promising Option
Colorectal cancer accounts for approximately 10% of cancer-related mortality in Western countries. The p...
Linking Hyperuricemia to Cancer: Emerging Evidence on Risk and Progression
Linking Hyperuricemia to Cancer: Emerging Evidence on Risk and Progression
Metabolic disorders significantly contribute to cancer burden globally. Uric acid (UA), a recognized metabolic risk factor...
Current State of Bladder Preservation in High Grade Non-Muscle Invasive Bladder Cancer and Localized Muscle Invasive Bladder Cancer
Current State of Bladder Preservation in High Grade Non-Muscle Invasive Bladder Cancer and Localized Muscle Invasive Bladder Cancer
In recent years, new, effective bladder sparing techniques have emerged as favorable options for patients with BCG-unrespo...
Social Needs in Cancer Survivors: A Scoping Review and Future Directions
Social Needs in Cancer Survivors: A Scoping Review and Future Directions
We conducted a scoping review to determine what is known about the prevalence and consequences of unmet social needs in U....
Liquid Biopsy in Hepatocellular Carcinoma: ctDNA as a Potential Biomarker for Diagnosis and Prognosis
Liquid Biopsy in Hepatocellular Carcinoma: ctDNA as a Potential Biomarker for Diagnosis and Prognosis
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, with rising incidence and mortali...
Correction to: Tivozanib Monotherapy in the Frontline Setting for Patients with Metastatic Renal Cell Carcinoma and Favorable Prognosis
Correction to: Tivozanib Monotherapy in the Frontline Setting for Patients with Metastatic Renal Cell Carcinoma and Favorable Prognosis
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Effectiveness and Safety of Immune Checkpoint Inhibitors in Colorectal Cancer: A Systematic Review of Real-World Studies
Effectiveness and Safety of Immune Checkpoint Inhibitors in Colorectal Cancer: A Systematic Review of Real-World Studies
Immune checkpoint inhibitors (ICIs) have demonstrated significant efficacy in the treatment of colorectal cancer (CRC). Ho...
State-of-the-art in Metastatic Uveal Melanoma Treatment: A 2025 Update
State-of-the-art in Metastatic Uveal Melanoma Treatment: A 2025 Update
Uveal melanoma (UM) is the most common intraocular malignancy in adults, representing a rare but aggressive melanoma subty...
Imiquimod for Anal High Grade Intraepithelial Neoplasia: A Systematic Review
Imiquimod for Anal High Grade Intraepithelial Neoplasia: A Systematic Review
This study aimed to investigate the efficacy of imiquimod in Anal High Grade Squamous Intraepithelial Lesion (HSI...
Acute Management of Hypercalcemia of Malignancy – A Review of Pathophysiology, Diagnosis, and Treatment
Acute Management of Hypercalcemia of Malignancy – A Review of Pathophysiology, Diagnosis, and Treatment
Hypercalcemia of malignancy is one of the most common metabolic disorders in patients with cancer and is associated with s...
Therapeutic Management of Metastatic Thymoma and Thymic Carcinoma
Therapeutic Management of Metastatic Thymoma and Thymic Carcinoma
Assess new options and best sequence or combination strategies for the treatment of metastatic thymic epithelial tumors. B...
Management of Metastatic Hormone Receptor-Positive Breast Cancer Beyond CDK4/6 Inhibitors
Management of Metastatic Hormone Receptor-Positive Breast Cancer Beyond CDK4/6 Inhibitors
Since the introduction of cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) in combination with endocrine therapy (ET) ...
Risk Stratification, Screening and Treatment of BRAF/MEK Inhibitors-Associated Cardiotoxicity
Risk Stratification, Screening and Treatment of BRAF/MEK Inhibitors-Associated Cardiotoxicity
In this review article we describe the cardiovascular adverse events associated with BRAF and MEK inhibitors as well as th...
Emerging Indications for Interventional Oncology: A Comprehensive Systematic Review of Image-Guided Thermal Ablation for Metastatic Non-cervical Lymph Node Disease
Emerging Indications for Interventional Oncology: A Comprehensive Systematic Review of Image-Guided Thermal Ablation for Metastatic Non-cervical Lymph Node Disease
Lymphatic node metastatic disease encompasses a distinct oncological entity which has been associated with poor prognosis....
CAR T-cell Therapy for Central Nervous System Lymphoma
CAR T-cell Therapy for Central Nervous System Lymphoma
While anti-CD19 CAR T-cell therapy represents a major advance in systemic diffuse large B-cell lymphomas, central nervous ...
Return to Intended Oncological Therapy: State of the Art and Perspectives
Return to Intended Oncological Therapy: State of the Art and Perspectives
Despite advances in surgical procedures, cancer recurrence still affects a substantial proportion of patients for whom sur...
First-Line Therapy in Metastatic, RAS Wild-Type, Left-Sided Colorectal Cancer: Should Everyone Receive Anti-EGFR Therapy?
First-Line Therapy in Metastatic, RAS Wild-Type, Left-Sided Colorectal Cancer: Should Everyone Receive Anti-EGFR Therapy?
This narrative review explores the efficacy and applicability of anti-EGFR therapy as the first-line treatment for patient...
The Difficult Airway in Patients with Cancer
The Difficult Airway in Patients with Cancer
The goal of this review is to provide an overview of difficult airway management in the cancer population. Difficult airwa...
Balancing Fertility Preservation and Treatment Efficacy in (Neo)adjuvant Therapy for Adolescent and Young Adult Breast Cancer Patients: a Narrative Review
Balancing Fertility Preservation and Treatment Efficacy in (Neo)adjuvant Therapy for Adolescent and Young Adult Breast Cancer Patients: a Narrative Review
Adolescent and young adult (AYA) breast cancer survivors face a significant risk of infertility due to the gonadotoxic eff...
Paediatric Acute Lymphoblastic Leukaemia: A Narrative Review of Current Knowledge and Advancements
Paediatric Acute Lymphoblastic Leukaemia: A Narrative Review of Current Knowledge and Advancements
This review aims to provide an update on current knowledge regarding paediatric acute lymphoblastic leukaemia (ALL), focus...
Tivozanib Monotherapy in the Frontline Setting for Patients with Metastatic Renal Cell Carcinoma and Favorable Prognosis
Tivozanib Monotherapy in the Frontline Setting for Patients with Metastatic Renal Cell Carcinoma and Favorable Prognosis
In this review, we discuss which patients with metastatic clear cell renal cell carcinoma (mRCC) may be most suitable for ...
Multiple Options: How to Choose Therapy in Frontline Metastatic Melanoma
Multiple Options: How to Choose Therapy in Frontline Metastatic Melanoma
Given the rapid development of multiple targeted and immune therapies for patients with advanced melanoma, it can be chall...
Management of Localized Melanoma in the Anti-PD-1 Era
Management of Localized Melanoma in the Anti-PD-1 Era
The management of cutaneous melanoma has rapidly progressed over the past decade following the introduction of effective s...
Screening and Testing for Homologous Recombination Repair Deficiency (HRD) in Breast Cancer: an Overview of the Current Global Landscape
Screening and Testing for Homologous Recombination Repair Deficiency (HRD) in Breast Cancer: an Overview of the Current Global Landscape
Homologous recombination repair deficiency (HRD) increases breast cancer susceptibility and influences both prophylactic a...
Perioperative Blood Transfusions and Cancer Progression: A Narrative Review
Perioperative Blood Transfusions and Cancer Progression: A Narrative Review
To examine the most recent evidence about known controversies on the effect of perioperative transfusion on cancer progres...
From Detection to Cure – Emerging Roles for Urinary Tumor DNA (utDNA) in Bladder Cancer
From Detection to Cure – Emerging Roles for Urinary Tumor DNA (utDNA) in Bladder Cancer
This review sought to define the emerging roles of urinary tumor DNA (utDNA) for diagnosis, monitoring, and treatment of b...
Palliative Rehabilitation in Patients with Cancer: Definitions, Structures, Processes and Outcomes
Palliative Rehabilitation in Patients with Cancer: Definitions, Structures, Processes and Outcomes
This review examines the literature on palliative rehabilitation for patients with advanced cancer, focusing on definition...
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