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Predictors of weaning failure in ventilated intensive care patients: a systematic evidence map
Predictors of weaning failure in ventilated intensive care patients: a systematic evidence map
Ventilator weaning is of great importance for intensive care patients in order to avoid complications caused by prolonged ...
Based -evidence, an intervention study to improve sleep quality in awake adult ICU patients: a prospective, single-blind, clustered controlled trial
Based -evidence, an intervention study to improve sleep quality in awake adult ICU patients: a prospective, single-blind, clustered controlled trial
Evidence-based guidelines advocate promoting sleep in intensive care unit (ICU) patients, yet many patients experience poo...
Impact of fever on the outcome non-anoxic acute brain injury patients: a systematic review and meta-analysis
Impact of fever on the outcome non-anoxic acute brain injury patients: a systematic review and meta-analysis
Fever is a common condition in intensive care unit (ICU) patients, with an incidence between 30 and 50% in non-neurologica...
The long-term conditional mortality rate in older ICU patients compared to the general population
The long-term conditional mortality rate in older ICU patients compared to the general population
Understanding how preexisting comorbidities may interact with a critical illness is important for the assessment of long-t...
Redefining urine output thresholds for acute kidney injury criteria in critically Ill patients: a derivation and validation study
Redefining urine output thresholds for acute kidney injury criteria in critically Ill patients: a derivation and validation study
The current definition of acute kidney injury (AKI) includes increased serum creatinine (sCr) concentration and decreased ...
The role of lipid emulsions containing omega-3 fatty acids for medical and surgical critical care patients
The role of lipid emulsions containing omega-3 fatty acids for medical and surgical critical care patients
In critical illness the regulation of inflammation and oxidative stress can improve patient outcomes, and thus omega-3 pol...
High expression of L-GILZ transcript variant 1 (GILZ TV 1) is associated with increased 30-day sepsis mortality, and a high expression ratio possibly contraindicates hydrocortisone administration
High expression of L-GILZ transcript variant 1 (GILZ TV 1) is associated with increased 30-day sepsis mortality, and a high expression ratio possibly contraindicates hydrocortisone administration
Sepsis presents a challenge due to its complex immune responses, where balance between inflammation and anti-inflammation ...
Effects of different VV ECMO blood flow rates on lung perfusion assessment by hypertonic saline bolus-based electrical impedance tomography
Effects of different VV ECMO blood flow rates on lung perfusion assessment by hypertonic saline bolus-based electrical impedance tomography
Our study aimed to investigate the effects of different extracorporeal membrane oxygenation (ECMO) blood flow rates on lun...
Lower airway microbiota compositions differ between influenza, COVID-19 and bacteria-related acute respiratory distress syndromes
Lower airway microbiota compositions differ between influenza, COVID-19 and bacteria-related acute respiratory distress syndromes
Acute respiratory distress syndrome (ARDS) is responsible for 400,000 deaths annually worldwide. Few improvements have bee...
Rapidly improving ARDS differs clinically and biologically from persistent ARDS
Rapidly improving ARDS differs clinically and biologically from persistent ARDS
Rapidly improving acute respiratory distress syndrome (RIARDS) is an increasingly appreciated subgroup of ARDS in which hy...
Respiratory drive heterogeneity associated with systemic inflammation and vascular permeability in acute respiratory distress syndrome
Respiratory drive heterogeneity associated with systemic inflammation and vascular permeability in acute respiratory distress syndrome
In acute respiratory distress syndrome (ARDS), respiratory drive often differs among patients with similar clinical charac...
Case study observational research: inflammatory cytokines in the bronchial epithelial lining fluid of COVID-19 patients with acute hypoxemic respiratory failure
Case study observational research: inflammatory cytokines in the bronchial epithelial lining fluid of COVID-19 patients with acute hypoxemic respiratory failure
In this study, the concentrations of inflammatory cytokines were measured in the bronchial epithelial lining fluid (ELF) a...
Early administration of high protein for critically ill patients with acute kidney injury?
Early administration of high protein for critically ill patients with acute kidney injury?
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Reflections from the bedside: a nursing perspective on three decades of intensive care
Reflections from the bedside: a nursing perspective on three decades of intensive care
Since critical care’s inception in the 1950s, nursing has been central in its development. Critical care nurses were and r...
Whole blood transcriptomics identifies subclasses of pediatric septic shock
Whole blood transcriptomics identifies subclasses of pediatric septic shock
Sepsis is a highly heterogeneous syndrome, which has hindered the development of effective therapies. This has prompted in...
Do critical illness survivors with multimorbidity need a different model of care?
Do critical illness survivors with multimorbidity need a different model of care?
There is currently a lack of evidence on the optimal strategy to support patient recovery after critical illness. Previous...
Meta-analysis of pulse pressure variation (PPV) and stroke volume variation (SVV) studies: a few rotten apples can spoil the whole barrel
Meta-analysis of pulse pressure variation (PPV) and stroke volume variation (SVV) studies: a few rotten apples can spoil the whole barrel
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Proenkephalin as a biomarker correlates with acute kidney injury: a systematic review with meta-analysis and trial sequential analysis
Proenkephalin as a biomarker correlates with acute kidney injury: a systematic review with meta-analysis and trial sequential analysis
Proenkephalin A 119-159 (PENK) is freely filtered in the glomerulus with plasma levels correlating with glomerular filtrat...
Association of autoimmune diseases with the occurrence and 28-day mortality of sepsis: an observational and Mendelian randomization study
Association of autoimmune diseases with the occurrence and 28-day mortality of sepsis: an observational and Mendelian randomization study
Observational studies have indicated a potential association between autoimmune diseases and the occurrence of sepsis, wit...
Potential confounders in linking elevated S100A8/A9 to left ventricular dysfunction in septic shock patients
Potential confounders in linking elevated S100A8/A9 to left ventricular dysfunction in septic shock patients
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Targeting the host response in sepsis: current approaches and future evidence
Targeting the host response in sepsis: current approaches and future evidence
Sepsis, a dysregulated host response to infection characterized by organ failure, is one of the leading causes of death wo...
Comparing outcomes of out-of-hospital cardiac arrest patients with initial shockable rhythm in Singapore and Osaka using population-based databases
Comparing outcomes of out-of-hospital cardiac arrest patients with initial shockable rhythm in Singapore and Osaka using population-based databases
Previous research indicated outcomes among refractory out-of-hospital cardiac arrest (OHCA) patients with initial shockabl...
Critical illness among patients experiencing homelessness: a retrospective cohort study
Critical illness among patients experiencing homelessness: a retrospective cohort study
To understand the epidemiology and healthcare use of critically ill patients experiencing homelessness compared to critica...
Prognostic value of capillary refill time in adult patients: a systematic review with meta-analysis
Prognostic value of capillary refill time in adult patients: a systematic review with meta-analysis
Acute circulatory failure leads to tissue hypoperfusion. Capillary refill time (CRT) has been widely studied, but its pred...
Iron as an emerging therapeutic target in critically ill patients
Iron as an emerging therapeutic target in critically ill patients
The multiple roles of iron in the body have been known for decades, particularly its involvement in iron overload diseases...
Remimazolam besylate versus propofol for deep sedation in critically ill patients: a randomized pilot study
Remimazolam besylate versus propofol for deep sedation in critically ill patients: a randomized pilot study
To compare the efficacy and safety of remimazolam besylate and propofol for deep sedation in critically ill patients. In t...
Combination of serum and peritoneal 1.3-beta-d-glucan can rule out intra-abdominal candidiasis in surgical critically ill patients: a multicenter prospective study
Combination of serum and peritoneal 1.3-beta-d-glucan can rule out intra-abdominal candidiasis in surgical critically ill patients: a multicenter prospective study
Intra-abdominal candidiasis (IAC) is difficult to predict in critically ill patients with intra-abdominal infection, leadi...
Publisher Correction to: Critical Illness Weakness, Polyneuropathy and Myopathy: Diagnosis, treatment, and long‑term outcomes
Publisher Correction to: Critical Illness Weakness, Polyneuropathy and Myopathy: Diagnosis, treatment, and long‑term outcomes
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Prognostic differences in sepsis caused by gram-negative bacteria and gram-positive bacteria: a systematic review and meta-analysis
Prognostic differences in sepsis caused by gram-negative bacteria and gram-positive bacteria: a systematic review and meta-analysis
Bacteria are the main pathogens that cause sepsis. The pathogenic mechanisms of sepsis caused by gram-negative and gram-po...
Dysnatremia at ICU admission and functional outcome of cardiac arrest: insights from four randomised controlled trials
Dysnatremia at ICU admission and functional outcome of cardiac arrest: insights from four randomised controlled trials
To evaluate the potential association between early dysnatremia and 6-month functional outcome after cardiac arrest. We po...
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