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SCI Abstract
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Developmental brain injury and social determinants of health: opportunities to combine preclinical models for mechanistic insights into recovery
Epidemiological studies show that social determinants of health are amongst the strongest factors associated with developm...
Developmental Neuroscience
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In utero exposure to valproic acid throughout pregnancy causes phenotypes of autism in offspring mice
Valproic acid (VPA) is an antiepileptic drug that inhibits the epileptic activity of neurons mainly by inhibiting sodium c...
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Paternal Deprivation and Female Biparental Family Rearing Induce Dendritic and Synaptic Changes in Octodon degus: II. Nucleus Accumbens
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Sexual dimorphism in the closure of the hippocampal postnatal critical period of synaptic plasticity after intrauterine growth restriction – link to oligodendrocyte and glial dysregulation
Intrauterine growth restriction (IUGR) resulting from hypertensive disease of pregnancy (HDP) leads to sexually dimorphic ...
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Beyond the rainbow: a review of advanced lineage tracing methodologies for interrogating the initiation, evolution, and recurrence of brain tumors
The mammalian forebrain is perhaps the pinnacle of evolution and one of the most complex structures in known existence. Th...
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Prenatal stress induces translational disruption associated with myelination deficits
Background: Disruptions to neurodevelopment is known to be linked to behavioural disorders in childhood and into adulthood...
Developmental Neuroscience
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Dendrimer conjugated glutamate carboxypeptidase II inhibitor restores microglial changes in a rabbit model of cerebral palsy
We have previously shown that maternal endotoxin exposure leads to a phenotype of cerebral palsy and pro-inflammatory micr...
Developmental Neuroscience
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A Proposed Human Structural Brain Connectivity Matrix in the Center for Morphometric Analysis Harvard-Oxford Atlas Framework: A historical perspective and future direction for enhancing the precision of human structural connectivity with a novel neuroanatomical typology.
A complete structural definition of the human nervous system must include delineation of its wiring diagram (e.g., [1]). T...
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The Outcomes of Maternal Immune Activation Induced with the Viral Mimetic Poly I:C on Microglia in Exposed Rodent Offspring
Maternal immune activation (MIA) can result from a variety of maternal inflammatory factors, including metabolic disorders...
Developmental Neuroscience
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Paternal Deprivation and Female Biparental Family Rearing Induce Dendritic and Synaptic Changes in Octodon degus: II. Nucleus Accumbens
While the majority of studies on the importance of parental caregiving on offspring behavioral and brain development focus...
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Alterations in the proteome of developing neocortical synaptosomes in the absence of MET signaling revealed by comparative proteomics
Alterations in the expression of genes encoding proteins involved in synapse formation, maturation and function are a hall...
Developmental Neuroscience
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Impact of macrocephaly, as an isolated trait, on EEG signal as measured by spectral power and multiscale entropy during the first year of life
Macrocephaly has been associated with neurodevelopmental disorders; however, it has been mainly studied in the context of ...
Developmental Neuroscience
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Contents Vol. 44, 2022
Developmental...
Developmental Neuroscience
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Microglial Characterization in Transient Human Neurodevelopmental Structures
Human neurodevelopment is characterized by the appearance, development, and disappearance or transformation of various tra...
Developmental Neuroscience
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Maternal immune activation by poly (I:C) exposure causes cerebral cortical dysgenesis through dysregulated cell cycle kinetics of neural stem/progenitor cells
Maternal immune activation reportedly causes dysregulation of the cell cycle in stem cells, and impairment of higher corti...
Developmental Neuroscience
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Cilia at the Crossroads of Tumor Treating Fields and Chemotherapy
Glioblastoma (GBM), the most common and lethal primary brain tumor in adults, requires multi-treatment intervention which ...
Developmental Neuroscience
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Caspase-3 inhibition toward perinatal protection of the developing brain from environmental stress
Throughout our lives, we are exposed to a variety of hazards, such as environmental pollutants and chemical substances tha...
Developmental Neuroscience
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