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Kuoxin Decoction Alleviated Left Ventricular Remodeling by Inhibiting Cardiomyocyte Apoptosis Through ASK1/JNK/Cx43 Signaling Pathway in cTnTR141W Transgenic Mice and in vitro
Kuoxin Decoction Alleviated Left Ventricular Remodeling by Inhibiting Cardiomyocyte Apoptosis Through ASK1/JNK/Cx43 Signaling Pathway in cTnTR141W Transgenic Mice and in vitro
To explore the potential of KXD in mitigating gap junction remodeling and apoptosis in DCM and to elucidate the complex mo...
Ursolic Acid Ameliorates Diabetic Nephropathy by Inhibiting JAK2/STAT3-Driven Ferroptosis: Mechanistic Insights from Network Pharmacology and Experimental Validation
Ursolic Acid Ameliorates Diabetic Nephropathy by Inhibiting JAK2/STAT3-Driven Ferroptosis: Mechanistic Insights from Network Pharmacology and Experimental Validation
Exploring the underlying mechanism of UA protection against DN by blocking JAK2/STAT3-mediated ferroptosis. Read more
Comparison of Oliceridine and Morphine in Postoperative Analgesia in Laparoscopic Total Hysterectomy, a Randomized Double-Blind Controlled Trial
Comparison of Oliceridine and Morphine in Postoperative Analgesia in Laparoscopic Total Hysterectomy, a Randomized Double-Blind Controlled Trial
To identify safer and more effective postoperative analgesic methods for patients undergoing laparoscopic total hysterecto...
Synergistic Potential of Trikatu Essential Oil as an Aromatherapy Agent: A Chemical and Mechanistic Review
Synergistic Potential of Trikatu Essential Oil as an Aromatherapy Agent: A Chemical and Mechanistic Review
Reviewing the antioxidant, anti-inflammatory, anxiolytic, and neuroprotective properties of the bioactive compounds in Tri...
Effects of Remimazolam-Propofol with Flumazenil Reversal on the Emergence Time and Hemodynamics of Patients Undergoing Laparoscopic Partial Hepatectomy: A Prospective Randomized Controlled Trial
Effects of Remimazolam-Propofol with Flumazenil Reversal on the Emergence Time and Hemodynamics of Patients Undergoing Laparoscopic Partial Hepatectomy: A Prospective Randomized Controlled Trial
Evaluating remimazolam-propofol with flumazenil reversal on the emergence time and hemodynamics of patients undergoing lap...
Therapeutic Implications of Traditional Chinese Medicine in Clinically Relevant Diseases: Perspectives From microRNA-Modulated Apoptotic Signaling
Therapeutic Implications of Traditional Chinese Medicine in Clinically Relevant Diseases: Perspectives From microRNA-Modulated Apoptotic Signaling
We comprehensively examine contemporary research investigating the correlation between miRNAs and anti-tumor TCMs alongsid...
Phase I Trial of Pegylated Liposomal Doxorubicin Combined with Ifosfamide for Advanced Soft Tissue Sarcoma
Phase I Trial of Pegylated Liposomal Doxorubicin Combined with Ifosfamide for Advanced Soft Tissue Sarcoma
This phase I study aimed to determine the MTD and to assess the safety of escalated doses of PLD in combination with a fix...
Stimuli-Responsive Drug Delivery Systems for Enhanced Melanoma Immunotherapy
Stimuli-Responsive Drug Delivery Systems for Enhanced Melanoma Immunotherapy
To clarify how stimuli-responsive DDSs enhance melanoma immunotherapy and guide their use as therapeutic agents. Read more
Determining the Preventive Effect of Topical Magnesium Sulfate Administration on Postoperative Sore Throat [Letter]
Determining the Preventive Effect of Topical Magnesium Sulfate Administration on Postoperative Sore Throat [Letter]
Letter for the article Comparison of Preoperative Topical Magnesium Sulfate Spraying and Magnesium Sulfate Gargling for th...
Bibliometric Analysis of Exosome Research in Spinal Cord Injury (2000–May 2024). Trends, Collaborations, and Emerging Insights
Bibliometric Analysis of Exosome Research in Spinal Cord Injury (2000–May 2024). Trends, Collaborations, and Emerging Insights
The present study was conducted to provide a systematic bibliometric analysis of research trends related to SCI and exosomes.
Wedelolactone Ameliorates Ischemic Stroke by Inhibiting Oxidative Damage and Ferroptosis via HIF-1α/SLC7A11/GPX4 Signaling
Wedelolactone Ameliorates Ischemic Stroke by Inhibiting Oxidative Damage and Ferroptosis via HIF-1α/SLC7A11/GPX4 Signaling
Revealing that the Wel could alleviate ischemic stroke by inhibiting oxidative damage and ferroptosis via HIF-1α/ SL...
Model Prediction of Infection Risk After Glucocorticoid Treatment for Severe Drug-Induced Liver Injury: Globulin is a Core Predictive Factor
Model Prediction of Infection Risk After Glucocorticoid Treatment for Severe Drug-Induced Liver Injury: Globulin is a Core Predictive Factor
This study developed a predictive model for infection after glucocorticoid therapy in patients with drug-induced liver inj...
Efficacy and Safety of Guben Kechuan Granules in the Treatment of Chronic Bronchitis: A Multi-Center and Randomized Controlled Trial
Efficacy and Safety of Guben Kechuan Granules in the Treatment of Chronic Bronchitis: A Multi-Center and Randomized Controlled Trial
Guben Kechuan Granules demonstrated significant efficacy and safety in CB management, alleviating clinical symptoms, reduc...
Danggui Buxue Decoction Alleviates Acute Hypoxia-Induced Sleep Disorders: Insights from in vivo and in silico Analyses
Danggui Buxue Decoction Alleviates Acute Hypoxia-Induced Sleep Disorders: Insights from in vivo and in silico Analyses
Danggui Buxue decoction as a promising candidate for mitigating AHISD through neuroprotective and anti-inflammatory mechan...
Thoracic Paravertebral Block with Liposomal Bupivacaine Versus Plain Bupivacaine in Patients Undergoing Thoracoscopic Lung Resection: A Randomized Controlled Study
Thoracic Paravertebral Block with Liposomal Bupivacaine Versus Plain Bupivacaine in Patients Undergoing Thoracoscopic Lung Resection: A Randomized Controlled Study
We designed a prospective, randomized controlled trial to compare the analgesic effectiveness of a thoracic paravertebral ...
Intranasal Esketamine Premedication Reduces Sevoflurane Requirements During Laryngeal Mask Airway Insertion in Pediatric Patients: A Randomized Controlled Trial
Intranasal Esketamine Premedication Reduces Sevoflurane Requirements During Laryngeal Mask Airway Insertion in Pediatric Patients: A Randomized Controlled Trial
This study evaluated whether intranasal esketamine premedication reduces sevoflurane requirements for laryngeal mask airwa...
Analysis of Blood Components and Target Prediction for the Combined Use of Dendrobium officinale Compound and Western Medicine in Antihypertensive Therapy Based on Network Pharmacology and Molecular Docking
Analysis of Blood Components and Target Prediction for the Combined Use of Dendrobium officinale Compound and Western Medicine in Antihypertensive Therapy Based on Network Pharmacology and Molecular Docking
Investigating the primary monomer components and the associated mechanisms of action of DOC in exerting antihypertensive e...
Xian Huang Fang Inhibits the PKCδ/MAPK Signaling Pathway to Attenuate Renal Tubular Epithelial Cell Senescence and Thereby Delay Renal Interstitial Fibrosis
Xian Huang Fang Inhibits the PKCδ/MAPK Signaling Pathway to Attenuate Renal Tubular Epithelial Cell Senescence and Thereby Delay Renal Interstitial Fibrosis
The objective of this study was to investigate the protective effects of Xian Huang Fang against renal fibrosis and the un...
Palmitoylethanolamide in the Treatment of Pain and Its Clinical Application Prospects
Palmitoylethanolamide in the Treatment of Pain and Its Clinical Application Prospects
To provide readers with a systematic review of the mechanisms of action and clinical applications of Palmitoylethanolamide...
Impact of Remimazolam on Postoperative Delirium in Elderly Non-Cardiac Surgery Patients Admitted to the ICU: A Retrospective Propensity Score Matched Study
Impact of Remimazolam on Postoperative Delirium in Elderly Non-Cardiac Surgery Patients Admitted to the ICU: A Retrospective Propensity Score Matched Study
This study selected patients who were transferred to the ICU postoperatively for evaluation, as the enhanced monitoring in...
The Effect of Intravenous Lidocaine on EC50 of Remifentanil for Preventing Cough During Emergence in Female for Thyroid Surgery Anesthesia
The Effect of Intravenous Lidocaine on EC50 of Remifentanil for Preventing Cough During Emergence in Female for Thyroid Surgery Anesthesia
The effect of intravenous lidocaine on EC50 of remifentanil for preventing cough during emergence in female for thyroid su...
A Novel Quaternary Ammonium N-Propylamiodarone Bromide Provides Long-Lasting Analgesia Against Corneal Pain
A Novel Quaternary Ammonium N-Propylamiodarone Bromide Provides Long-Lasting Analgesia Against Corneal Pain
N-propylamiodarone bromide (NPA) produced long-lasting analgesia against corneal injury without hampering corneal recovery...
Effect of Position-Based Dosing Strategy for Metaraminol on Neonatal Acid–Base Status During Elective Caesarean Delivery: A Noninferiority Randomised Controlled Trial
Effect of Position-Based Dosing Strategy for Metaraminol on Neonatal Acid–Base Status During Elective Caesarean Delivery: A Noninferiority Randomised Controlled Trial
A higher starting dose of metaraminol in the supine position will result in a non-inferior umbilical arterial pH compared ...
The Efficacy of Chaihu-Guizhi-Ganjiang Decoction on Chronic Non-Atrophic Gastritis with Gallbladder Heat and Spleen Cold Syndrome and Its Metabolomic Analysis: An Observational Controlled Before-After Clinical Trial [Response to Letter]
The Efficacy of Chaihu-Guizhi-Ganjiang Decoction on Chronic Non-Atrophic Gastritis with Gallbladder Heat and Spleen Cold Syndrome and Its Metabolomic Analysis: An Observational Controlled Before-After Clinical Trial [Response to Letter]
Response to Letter in regards to The Efficacy of Chaihu-Guizhi-Ganjiang Decoction on Chronic Non-Atrophic Gastritis with G...
Factors Affecting Vancomycin Trough Concentration; a Population Pharmacokinetic Model in Non-Critical Care Saudi Patients
Factors Affecting Vancomycin Trough Concentration; a Population Pharmacokinetic Model in Non-Critical Care Saudi Patients
A large between subject variability for clearance was best presented by the large variability in vancomycin trough concent...
Network Pharmacology and Metabolomics Reveal Anti-Ferroptotic Effects of Curcumin in Acute Kidney Injury
Network Pharmacology and Metabolomics Reveal Anti-Ferroptotic Effects of Curcumin in Acute Kidney Injury
Investigating the effects of Curcumin on acute kidney injury ferroptosis.
Using Network Pharmacology and in vivo Experiments to Uncover the Mechanisms of Radix Paeoniae Rubra and Radix Angelicae Sinensis Granules in Treating Diabetes Mellitus-Induced Erectile Dysfunction
Using Network Pharmacology and in vivo Experiments to Uncover the Mechanisms of Radix Paeoniae Rubra and Radix Angelicae Sinensis Granules in Treating Diabetes Mellitus-Induced Erectile Dysfunction
The mechanisms and targets of Radix Paeoniae Rubra and Radix Angelicae Sinensis Granules (RAG) in treating DMED using netw...
Comprehensive Assessment of PCSK9 Inhibitors for Lipid Management: Scientific Guidance Based on Drug Selection Recommendations for Chinese Medical Institutions
Comprehensive Assessment of PCSK9 Inhibitors for Lipid Management: Scientific Guidance Based on Drug Selection Recommendations for Chinese Medical Institutions
This study evaluated four pcsk9 inhibitors: evolocumab, alirocumab, inclisiran & tafolecimab marketed in China by usin...
Unveiling the Mechanisms and Therapeutic Effects of Xiaoyao Sanjie Decoction in Triple-Negative Breast Cancer: A Network Pharmacology and Experimental Validation Approach
Unveiling the Mechanisms and Therapeutic Effects of Xiaoyao Sanjie Decoction in Triple-Negative Breast Cancer: A Network Pharmacology and Experimental Validation Approach
Verifying the efficacy of Xiaoyao Sanjie Decoction and its active component in the treatment of TNBC and explored its pote...
External Validation of the Population Pharmacokinetic Models of Amisulpride and Remedial Strategies for Delayed or Missed Doses
External Validation of the Population Pharmacokinetic Models of Amisulpride and Remedial Strategies for Delayed or Missed Doses
Evaluating the predictive performance of published amisulpride population pharmacokinetic models in schizophrenia patients...
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