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HOXC10 promotes hypertrophic scar fibroblast fibrosis through the regulation of STMN2 and the TGF-β/Smad signaling pathway
HOXC10 promotes hypertrophic scar fibroblast fibrosis through the regulation of STMN2 and the TGF-β/Smad signaling pathway
The pathophysiology of hypertrophic scar (HS) shares similarities with cancer. HOXC10, a gene significantly involved in ca...
Somatostatin-immunoreactive neurons of the rat gut during the development
Somatostatin-immunoreactive neurons of the rat gut during the development
Somatostatin (SST) is a peptide expressed in the peripheral and central nervous systems, as well as in endocrine and immun...
An alternative approach of TUNEL assay to specifically characterize DNA fragmentation in cell model systems
An alternative approach of TUNEL assay to specifically characterize DNA fragmentation in cell model systems
DNA damage is one of the most important effects induced by chemical agents. We report a comparative analysis of DNA fragme...
Complex shape markers can detect alterations in the spatial distribution of cell nuclei in human lung squamous cell carcinoma: a useful tool for automatic analysis?
Complex shape markers can detect alterations in the spatial distribution of cell nuclei in human lung squamous cell carcinoma: a useful tool for automatic analysis?
Lung cancer is the leading cause of cancer-related death. The use of computational methods to quantify changes that are no...
Identification and culture of functional salivary gland ductal epithelial cells
Identification and culture of functional salivary gland ductal epithelial cells
Sialadenitis is a prevalent salivary gland disease resulting in decreased salivary flow rate. To date, little is known abo...
Expression of mRNA for molecules that regulate angiogenesis, endothelial cell survival, and vascular permeability is altered in endothelial cells isolated from db/db mouse hearts
Expression of mRNA for molecules that regulate angiogenesis, endothelial cell survival, and vascular permeability is altered in endothelial cells isolated from db/db mouse hearts
Metabolic syndrome (MetS) is a condition that includes symptoms, such as obesity, hyperglycemia, and hypertension, which e...
Anti-inflammatory and glial response maintain normal colon function in trimethyltin-treated rats
Anti-inflammatory and glial response maintain normal colon function in trimethyltin-treated rats
Studies on the contribution of enteric neuropathy and intestinal homeostasis to central nervous system degeneration using ...
Specificity of widely used lectins as probed with oligosaccharide and plant polysaccharide arrays
Specificity of widely used lectins as probed with oligosaccharide and plant polysaccharide arrays
Glycan-binding specificity was studied for Jacalin, RCA 120, SBA, PHA-L, PHA-E, WGA, UEA, AAL, LTL, LEL, SNA, DSA, LCA, MA...
Be bold, start cold! cold formalin fixation of colorectal cancer specimens granted superior DNA and RNA quality for downstream molecular analysis
Be bold, start cold! cold formalin fixation of colorectal cancer specimens granted superior DNA and RNA quality for downstream molecular analysis
The use of cold formalin fixation (CFF; i.e., fixating tissue samples with 4 °C precooled formalin) recently...
Expression of SARS-CoV-2 entry molecules ACE2, NRP1, TMPRSS2, and FURIN in the reproductive tissues of male macaques
Expression of SARS-CoV-2 entry molecules ACE2, NRP1, TMPRSS2, and FURIN in the reproductive tissues of male macaques
Coronavirus disease 2019 (COVID-19) reportedly affects male reproductive function by causing spermatogenesis dysfunction a...
Changes in human skin composition due to intrinsic aging: a histologic and morphometric study
Changes in human skin composition due to intrinsic aging: a histologic and morphometric study
Skin represents the main barrier against the external environment, but also plays a role in human relations, as one of the...
Short and long-term 2100 MHz radiofrequency radiation causes endoplasmic reticulum stress in rat testis
Short and long-term 2100 MHz radiofrequency radiation causes endoplasmic reticulum stress in rat testis
Long-term radiofrequency radiation (RFR) exposure, which adversely affects organisms, deteriorates testicular functions. M...
Immunohistochemical analysis and distribution of epithelial mast cells in the rat larynx and trachea
Immunohistochemical analysis and distribution of epithelial mast cells in the rat larynx and trachea
Mast cells (MCs) in rat airways have been classified into two subtypes: epithelial MCs and connective tissue MCs (CTMCs). ...
FOXM1 requires IDH1 for late genes expression in mitotic cells
FOXM1 requires IDH1 for late genes expression in mitotic cells
Isocitrate dehydrogenase 1 (IDH1) is a metabolic enzyme that converts isocitrate to α-ketoglutarate in cells. However...
Establishment of a 3D organoid culture model for the investigation of adult slow-cycling putative intestinal stem cells
Establishment of a 3D organoid culture model for the investigation of adult slow-cycling putative intestinal stem cells
The study of intestinal stem cells is a prerequisite for the development of therapies aimed at regenerating the gut. To en...
Distribution and morphologic characterization of telocytes in rat ovary and uterus: insights from ultrastructural and immunohistochemical analysis
Distribution and morphologic characterization of telocytes in rat ovary and uterus: insights from ultrastructural and immunohistochemical analysis
Telocytes (TCs) are characterized by a small oval-shaped cell body with long prolongations that are called telopods (Tps)....
Stage-specific expression of Toll-like receptors in the seminiferous epithelium of mouse testis
Stage-specific expression of Toll-like receptors in the seminiferous epithelium of mouse testis
Genes encoding Toll-like receptors (TLRs) are expressed by germ cells in the mouse testis. Nevertheless, the expression of...
MEIKIN expression and its C-terminal phosphorylation by PLK1 is closely related the metaphase–anaphase transition by affecting cyclin B1 and Securin stabilization in meiotic oocyte
MEIKIN expression and its C-terminal phosphorylation by PLK1 is closely related the metaphase–anaphase transition by affecting cyclin B1 and Securin stabilization in meiotic oocyte
Oocyte meiotic maturation failure and chromosome abnormality is one of the main causes of infertility, abortion, and disea...
Effects of ∆-9 tetrahydrocannabinol on the small intestine altered by high fructose diet: A Histopathological study
Effects of ∆-9 tetrahydrocannabinol on the small intestine altered by high fructose diet: A Histopathological study
The consumption of fructose is increasing day by day. Understanding the impact of increasing fructose consumption on the s...
iRhom2 deficiency reduces sepsis-induced mortality associated with the attenuation of lung macrophages in mice
iRhom2 deficiency reduces sepsis-induced mortality associated with the attenuation of lung macrophages in mice
Sepsis has a high mortality rate and leads to multi-organ failure, including lung injury. Inactive rhomboid protease famil...
Identification of neutrophils and eosinophils in upper airway mucosa with immunofluorescence multiplex image cytometry
Identification of neutrophils and eosinophils in upper airway mucosa with immunofluorescence multiplex image cytometry
Characterization of inflammation in chronic rhinosinusitis with (CRSwNP) and without nasal polyps (CRSsNP) is an ongoing r...
The emerging role of the semaphorin family in cartilage and osteoarthritis
The emerging role of the semaphorin family in cartilage and osteoarthritis
In the pathogenesis of osteoarthritis, various signaling pathways may influence the bone joint through a common terminal p...
Development and functional testing of a novel in vitro delayed scratch closure assay
Development and functional testing of a novel in vitro delayed scratch closure assay
As the development of chronic wound therapeutics continues to expand, the demand for advanced assay systems mimicking the ...
Effect of elevated temperature and hydrocortisone addition on the proliferation of fibroblasts
Effect of elevated temperature and hydrocortisone addition on the proliferation of fibroblasts
Hyperthermia along with hydrocortisone (HC) are proven teratogens that can negatively influence embryo development during ...
Antioxidant supplementation may effect DNA methylation patterns, apoptosis, and ROS levels in developing mouse embryos
Antioxidant supplementation may effect DNA methylation patterns, apoptosis, and ROS levels in developing mouse embryos
This study was designed to address the question: does antioxidant-containing embryo culture media affect DNA methyltransfe...
Allyl isothiocyanate regulates oxidative stress, inflammation, cell proliferation, cell cycle arrest, apoptosis, angiogenesis, invasion and metastasis via interaction with multiple cell signaling pathways
Allyl isothiocyanate regulates oxidative stress, inflammation, cell proliferation, cell cycle arrest, apoptosis, angiogenesis, invasion and metastasis via interaction with multiple cell signaling pathways
Cancer growth is a molecular mechanism initiated by genetic and epigenetic modifications that are involved in cell prolife...
Placental progesterone and its receptor in HIV-infected pre-eclamptic women
Placental progesterone and its receptor in HIV-infected pre-eclamptic women
Given the high prevalence of HIV infection and pre-eclampsia (PE) in South Africa, this study evaluated and compared the p...
Editorial: Histochemistry and Cell Biology implements new submission guidelines for image presentation and image analysis
Editorial: Histochemistry and Cell Biology implements new submission guidelines for image presentation and image analysis
Journal “Instructions for authors” typically describe in more or less detail how manuscript figures should be prepared for...
Local fractal dimension of collagen detects increased spatial complexity in fibrosis
Local fractal dimension of collagen detects increased spatial complexity in fibrosis
Increase of collagen content and reorganization characterizes fibrosis but quantifying the latter remains challenging. Spa...
Cleaved caspase-3 is present in the majority of glial cells in the intact rat spinal cord during postnatal life
Cleaved caspase-3 is present in the majority of glial cells in the intact rat spinal cord during postnatal life
Cell death is an essential process that occurs during the development of the central nervous system. Despite the availabil...
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